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ACS Medicinal Chemistry Letters, ISSN 1948-5875, 02/2011, Volume 2, Issue 2, pp. 91 - 96
Fatty acid amide hydrolase (FAAH) is an integral membrane serine hydrolase that degrades the fatty acid amide family of signaling lipids, including the... 
endocannabinoid | FAAH | irreversible inhibitor | clinical candidate | ALPHA-KETOHETEROCYCLE INHIBITORS | TARGET | URB597 | CHEMISTRY, MEDICINAL | MECHANISM | ANANDAMIDE | INACTIVATION | ENZYME | ACID AMIDE HYDROLASE | ESTERS | CHEMISTRY
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 1996, Volume 6, Issue 12, pp. 1361 - 1366
A series of 4-bromo-1-methoxy-N-[2-(4-aryl-1-piperazinyl)ethyl]-2-naphthalenecarboxamide dopamine (DA) D-3 receptor agonists has been identified. These... 
CHEMISTRY, ORGANIC | CHEMISTRY, MEDICINAL
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 06/1996, Volume 6, Issue 12, pp. 1361 - 1366
A series of 4-bromo-1-methoxy-N-[2-(4-aryl-1-piperazinyl)ethyl]-2- naphthalenecarboxamide dopamine (DA) D receptor agonists has been identified. These... 
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 1992, Volume 35, Issue 19, pp. 3429 - 3447
To improve upon the activity and properties of the 3-aryl-7-chloro-3,4- dihydro-1,9(2H,10H)-acridinediones, a variety of 1-[(alkylamino)alkylene]imino... 
Acridines - chemistry | Acridines - chemical synthesis | Animals | Antimalarials - chemistry | Acridines - therapeutic use | Antimalarials - therapeutic use | Mice | Structure-Activity Relationship | Malaria - drug therapy | Antimalarials - chemical synthesis | Plasmodium berghei - drug effects | Haplorhini
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 09/1992, Volume 35, Issue 19, pp. 3429 - 3447
To improve upon the activity and properties of the 3-aryl-7-chloro-3,4-dihydro-1,9(2H,10H)-acridinediones, a variety of 1-[(alkylamino)alkylene]imino... 
CHEMISTRY, MEDICINAL | AGENTS
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 1987, Volume 30, Issue 5, pp. 906 - 911
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/1987, Volume 30, Issue 5, pp. 906 - 911
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 1991, Volume 1, Issue 3, pp. 147 - 150
An oxazolidinone analogue of pilocarpine demonstrates muscarinic agonist-like properties in vitro at the acetylcholine-receptor. Replacement of the carbon... 
CHEMISTRY, ORGANIC | (+)-PILOCARPINE | CHEMISTRY, MEDICINAL
Journal Article
Journal of Heterocyclic Chemistry, ISSN 0022-152X, 01/1981, Volume 18, Issue 1, pp. 117 - 121
Reactions of 2H‐3,1‐benzoxazine‐2,4‐(1H)dione (isatoic anhydride) (1) with anions of 1,4‐dihydro‐5H‐pyrazol‐5‐ones (2) gave pyrazolo[5,1‐6]quinazolin‐9‐ones... 
Journal Article
04/1981
Certain pyrazolo[5,1-b]quinazolin-9(4H)-ones are disclosed. These compounds prevent the allergic response in mammals. 
METALLURGY | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | ACYCLIC OR CARBOCYCLIC COMPOUNDS
Patent
07/1995, 6
Neurotensin antagonists are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful as central nervous... 
METALLURGY | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | ACYCLIC OR CARBOCYCLIC COMPOUNDS
Patent
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