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ACS Medicinal Chemistry Letters, ISSN 1948-5875, 02/2011, Volume 2, Issue 2, pp. 91 - 96
Fatty acid amide hydrolase (FAAH) is an integral membrane serine hydrolase that degrades the fatty acid amide family of signaling lipids, including the... 
endocannabinoid | FAAH | irreversible inhibitor | clinical candidate | ALPHA-KETOHETEROCYCLE INHIBITORS | TARGET | URB597 | CHEMISTRY, MEDICINAL | MECHANISM | ANANDAMIDE | INACTIVATION | ENZYME | ACID AMIDE HYDROLASE | ESTERS | CHEMISTRY
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 1998, Volume 8, Issue 12, pp. 1499 - 1502
PD 108635 (1) was identified as a potent dopamine D-4 ligand and we wanted to replace the benzylic alcohol with a metabolically more stable moiety.... 
CLOZAPINE | REDUCED HALOPERIDOL | CHEMISTRY, MEDICINAL | ANTAGONIST | NEUROLEPTICS | CHEMISTRY, ORGANIC | D4 RECEPTORS | BINDING
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 06/1998, Volume 8, Issue 12, pp. 1499 - 1502
PD 108635 (1) was identified as a potent dopamine D ligand and we wanted to replace the benzylic alcohol with a metabolically more stable moiety.... 
Animals | Receptors, Dopamine D4 | Stereoisomerism | X-Ray Diffraction | Receptors, Dopamine D2 - drug effects | Motor Activity - drug effects | Rats | Indoles - pharmacology | Structure-Activity Relationship | Indoles - chemistry | Receptors, Serotonin - metabolism
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 2006, Volume 16, Issue 9, pp. 2337 - 2340
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2000, Volume 43, Issue 5, pp. 984 - 994
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 09/1997, Volume 7, Issue 18, pp. 2403 - 2408
The dopamine D receptor is an attractive target for the treatment of schizophrenia. We identified PD137557 (V) as a ligand for the D receptor and desired to... 
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 1997, Volume 7, Issue 18, pp. 2403 - 2408
The dopamine D-3 receptor is an attractive target for the treatment of schizophrenia. We identified PD137557 (V) as a ligand for the D-2 receptor and desired... 
CHEMISTRY, ORGANIC | K EE CHEMISTRY, ORGANIC | CHEMISTRY, MEDICINAL | RAT-BRAIN | BINDING | K DX CHEMISTRY, MEDICINAL
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 06/1996, Volume 6, Issue 12, pp. 1361 - 1366
A series of 4-bromo-1-methoxy-N-[2-(4-aryl-1-piperazinyl)ethyl]-2- naphthalenecarboxamide dopamine (DA) D receptor agonists has been identified. These... 
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 1996, Volume 6, Issue 12, pp. 1361 - 1366
A series of 4-bromo-1-methoxy-N-[2-(4-aryl-1-piperazinyl)ethyl]-2-naphthalenecarboxamide dopamine (DA) D-3 receptor agonists has been identified. These... 
CHEMISTRY, ORGANIC | CHEMISTRY, MEDICINAL
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 1991, Volume 1, Issue 3, pp. 147 - 150
An oxazolidinone analogue of pilocarpine demonstrates muscarinic agonist-like properties in vitro at the acetylcholine-receptor. Replacement of the carbon... 
CHEMISTRY, ORGANIC | (+)-PILOCARPINE | CHEMISTRY, MEDICINAL
Journal Article
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