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1. Full Text Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research
by Maas, Andrew I R and Menon, David K and Adelson, P David and Andelic, Nada and Bell, Michael J and Belli, Antonio and Bragge, Peter and Brazinova, Alexandra and Büki, András and Chesnut, Randall M and Citerio, Giuseppe and Coburn, Mark and Cooper, D Jamie and Crowder, A Tamara and Czeiter, Endre and Czosnyka, Marek and Diaz-Arrastia, Ramon and Dreier, Jens P and Duhaime, Ann-Christine and Ercole, Ari and van Essen, Thomas A and Feigin, Valery L and Gao, Guoyi and Giacino, Joseph and Gonzalez-Lara, Laura E and Gruen, Russell L and Gupta, Deepak and Hartings, Jed A and Hill, Sean and Jiang, Ji-yao and Ketharanathan, Naomi and Kompanje, Erwin J O and Lanyon, Linda and Laureys, Steven and Lecky, Fiona and Levin, Harvey and Lingsma, Hester F and Maegele, Marc and Majdan, Marek and Manley, Geoffrey and Marsteller, Jill and Mascia, Luciana and McFadyen, Bradford and McFadyen, Charles and Mondello, Stefania and Newcombe, Virginia and Palotie, Aarno and Parizel, Paul M and Peul, Wilco and Piercy, James and Polinder, Suzanne and Puybasset, Louis and Rasmussen, Todd E and Rossaint, Rolf and Smielewski, Peter and Söderberg, Jeannette and Stanworth, Simon J and Stein, Murray B and von Steinbüchel, Nicole and Stewart, William and Steyerberg, Ewout W and Stocchetti, Nino and Synnot, Anneliese and Te Ao, Braden and Tenovuo, Olli and Theadom, Alice and Tibboel, Dick and Videtta, Walter and Wang, Kevin K W and Williams, W Huw and Williams, Guy and Wilson, Lindsay and Yaffe, Kristine and Adams, Hadie and Agnoletti, Vanni and Allanson, Judith and Amrein, Krisztina and Andaluz, Norberto and Anke, Audny and Antoni, Anna and van As, Arjan Bastiaan and Audibert, Gérard and Azaševac, Antun and Azouvi, Philippe and Azzolini, Maria Luisa and Baciu, Camelia and Badenes, Rafael and Barlow, Karen M and Bartels, Ronald and Bauerfeind, Ursula and Beauchamp, Miriam and Beer, Darcy and Beer, Ronny and Belda, Francisco Javier and Bellander, Bo-Michael and Bellier, Rémy and Benali, Habib and Benard, Thierry and Beqiri, Valzerda and Beretta, Luigi and ... and InTBIR Participants Investigators and InTBIR Participants and Investigators
The Lancet Neurology, ISSN 1474-4422, 12/2017, Volume 16, Issue 12, pp. 987 - 1048
[...]it might also be possible to specifically target individuals to address their patterns of risk-taking behaviour.183 Irrespective of the target population,... 
DIAGNOSTIC MANAGEMENT STRATEGIES | UNITED-STATES | EMERGENCY-DEPARTMENT VISITS | ACUTE SUBDURAL-HEMATOMA | GLASGOW COMA SCALE | MILD HEAD-INJURY | RANDOMIZED CONTROLLED-TRIAL | HIGH-SCHOOL FOOTBALL | CLINICAL NEUROLOGY | PATIENT-REPORTED OUTCOMES | EVIDENCE-BASED MEDICINE | Brain Injuries, Traumatic - prevention & control | Brain Injuries, Traumatic - therapy | Brain Injuries - etiology | Brain Injuries, Traumatic - epidemiology | Humans | Brain Injuries - prevention & control | Nuclear magnetic resonance--NMR | Traumatic brain injury | Mortality | Health care policy | Patients | Trauma | Epidemiology | Evidence-based medicine | Medicine | Consortia | Disease prevention | Disability | Brain research | Researchers | Research methodology | Trauma centers | Clinical medicine | Public health
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2. Full Text Combining Brain Microdialysis and Translational Pharmacokinetic Modeling to Predict Drug Concentrations in Pediatric Severe Traumatic Brain Injury: The Next Step Toward Evidence-Based Pharmacotherapy?
by Ketharanathan, Naomi and Yamamoto, Yumi and Rohlwink, Ursula K and Wildschut, Enno D and Mathôt, Ron A.A and de Lange, Elizabeth C.M and de Wildt, Saskia N and Argent, Andrew C and Tibboel, Dick and Figaji, Anthony A
Journal of Neurotrauma, ISSN 0897-7151, 01/2019, Volume 36, Issue 1, pp. 111 - 117
Evidence-based analgosedation in severe pediatric traumatic brain injury (pTBI) management is lacking, and improved pharmacological understanding is needed.... 
Original Articles | pharmacokinetics | traumatic brain injury | microdialysis | morphine | pediatric | GUIDELINES | NEUROSCIENCES | CARE | CLINICAL NEUROLOGY | CRITICAL CARE MEDICINE | Coma | Plasma | Pediatrics | Translation | Intensive care | Traumatic brain injury | Morphine | Pharmacology | Metabolism | Patients | Computer programs | Children & youth | Studies | Brain research | Microdialysis | Metabolites | Population | Physiology | Children | Pharmacokinetics | Drug dosages
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3. Full Text Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI): A Prospective Longitudinal Observational Study
by Maas, Andrew I.R and Menon, David K and Steyerberg, Ewout W and Citerio, Giuseppe and Lecky, Fiona and Manley, Geoffrey T and Hill, Sean and Legrand, Valerie and Sorgner, Annina and CENTER-TBI Participants and CENTER-TBI Participants and Investigators
Neurosurgery, ISSN 0148-396X, 01/2015, Volume 76, Issue 1, pp. 67 - 80
BACKGROUND:Current classification of traumatic brain injury (TBI) is suboptimal, and management is based on weak evidence, with little attempt to personalize... 
Comparative effectiveness research | Traumatic brain injury | Protocol | Clinical study | SURGERY | OUTCOMES | TRENDS | CLINICAL NEUROLOGY | Brain Injuries - classification | Prospective Studies | Outcome Assessment (Health Care) | Europe | Humans | Male | Tomography, X-Ray Computed | Brain Injuries - therapy | Brain Injuries - diagnosis | Comparative Effectiveness Research | Adult | Female | Israel | Child | Longitudinal Studies | Research Design
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4. Full Text Health-related quality of life, emotional and behavioral problems in mild to moderate prematures at (pre-)school age
by Ketharanathan, Naomi and Lee, Weiling and de Mol, Amerik C
Early Human Development, ISSN 0378-3782, 2011, Volume 87, Issue 10, pp. 705 - 709
Abstract Background There is a gap in the knowledge of longterm outcome of mild to moderate prematures compared to the extreme prematures or very low birth... 
Advanced Basic Science | Neonatal and Perinatal Medicine | Premature | Health-related quality of life | Near term | Newborn | Neonate | Behavior | MORTALITY | CHILDREN BORN PRETERM | ADULTHOOD | OBSTETRICS & GYNECOLOGY | PRESCHOOL-CHILDREN | BIRTH-WEIGHT INFANTS | 36 WEEKS GESTATION | MORBIDITY | PEDIATRICS | NEAR-TERM INFANTS | COHORT | OUTCOMES | Continuous Positive Airway Pressure | Child Behavior Disorders - psychology | Infant, Premature - psychology | Follow-Up Studies | Humans | Child, Preschool | Male | Gestational Age | Emotions | Socioeconomic Factors | Child Behavior Disorders - etiology | Sleep | Parents - psychology | Child Behavior Disorders - epidemiology | Quality of Life | Female | Surveys and Questionnaires | Infant, Newborn | Cohort Studies | Infants (Premature) | Children
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5. Full Text Analgosedation in paediatric severe traumatic brain injury (TBI): practice, pitfalls and possibilities
by Ketharanathan, Naomi and Yamamoto, Y and Rohlwink, U and Wildschut, Enno and Hunfeld, Maaike and de Lange, E.C.M and Tibboel, Dick
Child's Nervous System, ISSN 0256-7040, 10/2017, Volume 33, Issue 10, pp. 1703 - 1710
textabstractAnalgosedation is a fundamental part of traumatic brain injury (TBI) treatment guidelines, encompassing both first and second tier supportive... 
Paediatric | Analgesia | Neurosciences | Traumatic brain injury | Medicine & Public Health | Pharmacology | Neurosurgery | Sedation | SURGERY | INTRACRANIAL HYPERTENSION | HEAD-INJURY | EFFICACY | RESPIRATORY DEPRESSION | CRITICAL-CARE | CLINICAL NEUROLOGY | KETAMINE | CHILDREN | PRESSURE | PEDIATRICS | FENTANYL | Pediatrics | Brain | Care and treatment | Analysis | Patient outcomes | Drug therapy | Health aspects | Injuries | Special Annual Issue
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6. Full Text Variation in monitoring and treatment policies for intracranial hypertension in traumatic brain injury: A survey in 66 neurotrauma centers participating in the CENTER-TBI study
by Cnossen, Maryse and Huijben, J.A and van der Jagt, M and Volovici, V and van Essen, T and Polinder, Suzanne and Nelson, David and Ercole, A and Stocchetti, N and Citerio, G and Peul, Wilco and Maas, Anew I.R and Menon, David and Steyerberg, Ewout W and Lingsma, H.F and Adams, H and Alessano, M and Allanson, Judith and Amrein, K and Andaluz, N and Andelic, Nada and Anea, N and Aneassen, Lasse and Anke, A and Antoni, A and Ardon, H and Audibert, G and Auslands, K and Azouvi, P and Baciu, C and Bacon, A and Badenes, R and Baglin, T and Bartels, Ronald and Barzo, P and Bauerfeind, U and Beer, Ronny and Belda, F.J and Bellander, Bo-Michael and Belli, Antonio and Bellier, R and Benali, Habib and Benard, T and Berardino, Maurizio and Beretta, Luigi and Beynon, C and Bilotta, F and Binder, Harald and Biqiri, E and Blaabjerg, M and Lund, S.B and Bouzat, P and Bragge, P and Brazinova, A and Brehar, Felix and Brorsson, C and Buki, A and Bullinger, Monika and Bucková, V and Calappi, E and Cameron, Peter and Carbayo, L.G and Carise, E and Carpenter, Keri L.H and Castaño-León, A.M and Causin, F and Chevallard, G and Chieregato, Arturo and Citerio, Giuseppe and Cnossen, M and Coburn, Mark and Coles, Jonathan P and Cooper, J.D and Correia, M and Covic, Amra and Curry, Nicola and Czeiter, Ene and Czosnyka, Marek and Dahyot-Fizelier, C and Damas, François and Damas, Pierre and Dawes, Helen and De Keyser, V and Corte, Francesco and Depreitere, Bart and Ding, S and Dippel, Diederik and Dizdarevic, Kemal and Dulière, G.-L and Dzeko, A and Eapen, George and Engemann, H and Ercole, Ari and Esser, Patrick and Ezer, E and Fabricius, Martin and Feigin, V and Feng, J and Foks, K and Fossi, Francesca and ... and CENTER-TBI Investigators and CENTER-TBI investigators and on behalf of the CENTER-TBI investigators
Critical Care, ISSN 1364-8535, 09/2017, Volume 21, Issue 1, pp. 233 - 12
textabstractBackground: No definitive evidence exists on how intracranial hypertension should be treated in patients with traumatic brain injury (TBI). It is... 
Comparative effectiveness research | Survey | ICU | Traumatic brain injury | Intracranial hypertension | ICP | MODERATE | MANAGEMENT | CARE | PRESSURE | IMPACT | EUROPEAN-BRAIN | CRITICAL CARE MEDICINE | Medical policy | Brain | Analysis | Research | Drug therapy | Risk factors | Injuries | Studies | Intensive care | Brain research | Collaboration | Mortality | Questionnaires | Critical care | Patients | Trauma
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7. Full Text A review of blood transfusions in a trauma unit for young children
by Salverda, M and Ketharanathan, Naomi and Dijk, Monique and Beltchev, E and Buys, H and Numanoglu, Alp and As, Àrjan Bastiaan
S A M J South African Medical Journal, ISSN 0256-9574, 03/2017, Volume 107, Issue 3, pp. 227 - 231
textabstractBackground. Trauma is the leading cause of mortality and morbidity worldwide. Blood transfusions play an incremental role in the acute phase, yet... 
Children | Blood transfusion | Trauma | Injury | MEDICINE, GENERAL & INTERNAL | STRATEGIES
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8. Full Text Variation in structure and process of care in traumatic brain injury: Provider profiles of European Neurotrauma Centers participating in the CENTER-TBI study
by Cnossen, Maryse and Polinder, Suzanne and Lingsma, H.F and Maas, Anew and Menon, David and Steyerberg, Ewout and Adams, H and Alessano, M and Allanson, Judith and Amrein, K and Andaluz, N and Andelic, Nada and Anea, N and Aneassen, Lasse and Anke, A and Antoni, A and Ardon, H and Audibert, Gérard and Auslands, K and Azouvi, P and Baciu, C and Bacon, A and Badenes, R and Baglin, T and Bartels, R and Barzó, P and Bauerfeind, U and Beer, Ronny and Belda, F.J and Bellander, Bo-Michael and Belli, Antonio and Bellier, R and Benali, Habib and Benard, T and Berardino, Maurizio and Beretta, L and Beynon, C and Bilotta, F and Binder, Harald and Biqiri, E and Blaabjerg, M and Borgen, L.S and Bouzat, P and Bragge, P and Brazinova, Alexana and Brehar, Felix and Brorsson, C and Buki, A and Bullinger, Monika and Bučková, V and Calappi, E and Cameron, Peter and Carbayo, L.G and Carise, E and Carpenter, C and Castaño-León, A.M and Causin, F and Chevallard, G and Chieregato, Arturo and Citerio, Giuseppe and Coburn, Mark and Coles, Jonathan P and Cooper, J.D and Correia, M and Covic, Amra and Curry, Nicola and Czeiter, Ene and Czosnyka, Marek and Dahyot-Fizelier, C and Damas, François and Damas, Pierre and Dawes, Helen and De Keyser, V and Della Corte, Francesco and Depreitere, Bart and Ding, S and Dippel, Diederik and Dizdarevic, Kemal and Dulière, G.-L and Dzeko, A and Eapen, George and Engemann, H and Ercole, Ari and Esser, Patrick and Ezer, E and Fabricius, Martin and Feigin, V and Feng, J and Foks, K and Fossi, Francesca and Francony, G and Frantzén, Janek and Freo, U and Frisvold, Shirin Kordasti and Furmanov, A and Gagliardo, Pablo and Galanaud, Damien and Gao, Guoyi and Geleijns, Karin and Ghuysen, Alexane and ... and CENTER-Tbi Invest Participants and CENTER-TBI Investigators and Participants
PLoS ONE, ISSN 1932-6203, 08/2016, Volume 11, Issue 8, p. e0161367
textabstractIntroduction: The strength of evidence underpinning care and treatment recommendations in traumatic brain injury (TBI) is low. Comparative... 
MANAGEMENT | QUALITY | QUESTIONNAIRE | MULTIDISCIPLINARY SCIENCES | LENGTH | Brain | Complications and side effects | Care and treatment | Diagnosis | Research | Injuries | Medical research | Traumatic brain injury | Experts | Urban areas | Physicians | Critical care | Systematic review | Neurosurgery | Intracranial pressure | Epidemiology | Trauma | Patients | Annual reports | Studies | Brain research | Head injuries | Hospitals | Reproduction (copying) | Collaboration | Questionnaires | Rehabilitation | Variation | Public health
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