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1. Full Text Role of HHV-6 subtypes in accelerating EAE progression
by Zahednasab, Hamid and Keyvani, Hossein and Karampour, Sajad and Harirchian, Mohammad Hossein
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2018, Volume 115, Issue 52, pp. E12126 - E12126
Zahednasab et al comment on a study by Leibovitch et al in which they show that intranasal inoculations with human herpesvirus (HHV)-6A and HHV-6B accelerate... 
MULTIDISCIPLINARY SCIENCES | Multiple Sclerosis | Primates | Animals | Herpesviridae | Disease Progression | Herpesvirus 6, Human | Encephalitis | Immunization | Multiple sclerosis | Encephalomyelitis | Herpes viruses | Experimental allergic encephalomyelitis | Letter | Biological Sciences
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2. Full Text Metalloproteinase 9 as a biomarker of progressive multifocal leukoencephalopathy development in multiple sclerosis patients receiving natalizumab
by Zahednasab, Hamid and Harirchian, Mohammad Hossein and Karampoor, Sajad and Keyvani, Hossein
Annals of Neurology, ISSN 0364-5134, 10/2017, Volume 82, Issue 4, pp. 647 - 647
NEUROSCIENCES | CLINICAL NEUROLOGY | Multiple Sclerosis | Multiple Sclerosis, Relapsing-Remitting | Natalizumab | Humans | Biomarkers | Leukoencephalopathy, Progressive Multifocal | Matrix Metalloproteinase 9 | Multiple sclerosis | Metalloproteinase | Leukoencephalopathy | Progressive multifocal leukoencephalopathy
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3. Full Text The first clinical use of a recombinant Lactococcus lactis expressing human papillomavirus type 16 E7 oncogene oral vaccine: A phase I safety and immunogenicity trial in healthy women volunteers
by Mohseni, Amir Hossein and Taghinezhad-S, Sedigheh and Keyvani, Hossein
Molecular Cancer Therapeutics, ISSN 1535-7163, 10/2019, p. molcanther.0375.2019
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4. Full Text Extracellular overproduction of E7 oncoprotein of Iranian human papillomavirus type 16 by genetically engineered Lactococcus lactis
by Mohseni, Amir Hossein and Mohseni, Amir Hossein and Taghinezhad-S, Sedigheh and Taghinezhad-S, Sedigheh and Keyvani, Hossein and Keyvani, Hossein and Razavilar, Vadood and Razavilar, Vadood
BMC biotechnology, ISSN 1472-6750, 01/2019, Volume 19, Issue 1, pp. 8 - 13
BackgroundWe aimed at constructing Lactococcus lactis strains expressing HPV-16 recombinant E7 (rE7) oncoprotein and examining its overproduction ability... 
Batch and fed-batch fermentation | HPV-16 | Lactococcus lactis | Protein secretion | Optimization | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | NISIN PRODUCTION | EFFICIENT | Lactococcus lactis - genetics | Gene Expression | Immunization | Humans | Mice, Inbred C57BL | Papillomavirus E7 Proteins - immunology | Models, Molecular | Recombinant Proteins - biosynthesis | Fermentation | Animals | Genetic Engineering | Iran | Female | Papillomavirus E7 Proteins - biosynthesis | Batch Cell Culture Techniques - methods | Usage | Patient outcomes | Oral vaccines | Development and progression | Research | Recombinant proteins | Risk factors | Prevention | Complications and side effects | Lactococcus | Physiological aspects | Papillomavirus infections | Cervical cancer | Cell culture | Batch culture | Yeast | Peptides | CD8 antigen | Mucosa | Immunoglobulin G | Vaccination | Lymphocytes T | Vaccines | Immunoglobulin A | Experiments | Proteins | Cancer vaccines | Human papillomavirus | Microorganisms | Interleukin 2 | Lymphocytes | Intestine | Splenocytes | Bacteria | Recombinant | Antigens | Cultivation | Immune response (cell-mediated) | Vagina | Gene expression | Cervix | Immune response (humoral) | CD4 antigen | Immunogenicity | γ-Interferon | Protein expression | Genetic engineering | Mice
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5. Full Text Oral immunization with recombinant Lactococcus lactis NZ9000 expressing human papillomavirus type 16 E7 antigen and evaluation of its immune effects in female C57BL/6 mice
by Mohseni, Amir Hossein and Razavilar, Vadood and Keyvani, Hossein and Razavi, Mohammad Reza and Khavari‐Nejad, Ramazan Ali
Journal of Medical Virology, ISSN 0146-6615, 02/2019, Volume 91, Issue 2, pp. 296 - 307
The ORFs of both native and codon‐optimized E7 genes were successfully fused to SPusp45 signal peptide and expressed by a nisin‐controlled gene expression... 
Lactococcus lactis | oral immunization | vaccine | human papillomavirus type 16 (HPV‐16) | pNZ8123 | enzyme‐linked immunospot (ELISPOT) | enzyme-linked immunospot (ELISPOT) | human papillomavirus type 16 (HPV-16) | SYSTEM | CANCER | TUMORS | VACCINE VECTORS | LIVE VECTOR | STRATEGIES | VIROLOGY | NICE | OPTIMIZATION | MUCOSAL DELIVERY | Papillomaviruses | Antigens | Immunization | Analysis | Mice | T cells | Enzyme-linked immunosorbent assay | Cell culture | CD8 antigen | Mucosa | Vaccination | Antibodies | Lymphocytes T | Optimization | Anticancer properties | Proteins | Human papillomavirus | Lymphocytes | Intestine | Splenocytes | Recombinant | Nisin | Enzymes | Cytokines | Secretion | Oral administration | Gene expression | Immune response (humoral) | CD4 antigen | Antitumor activity | Interferon | Tumors
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6. Full Text Molecular screening and single nucleotide polymorphism typing of molluscum contagiosum virus (MCV) from genital specimens, between 2012 and 2015
by Taghinezhad-S, Sedigheh and Mohseni, Amir Hossein and Keyvani, Hossein and Ghobadi, Narges
Iranian Biomedical Journal, ISSN 1028-852X, 04/2018, Volume 22, Issue 2, pp. 129 - 133
The present study is the first comprehensive report of the Molluscum contagiosum virus (MCV) in Iran based on the molecular technique for differentiation and... 
Polymerase chain reaction | Molluscum contagiosum virus | Single nucleotide polymorphism | Warts | Typing | Pathogenesis | Molluscum contagiosum | Human immunodeficiency virus--HIV | Viruses | Single-nucleotide polymorphism | Epidemiology | Polymorphism | Short Communication
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7. Full Text Prevalence of Non-Alcoholic Fatty Liver Disease and Its Predictors in North of Iran
by Amirkalali, B and Poustchi, H and Keyvani, H and Khansari, MR and Ajdarkosh, H and Maadi, M and Sohrabi, MR and Zamani, F
IRANIAN JOURNAL OF PUBLIC HEALTH, ISSN 2251-6085, 09/2014, Volume 43, Issue 9, pp. 1275 - 1283
Background: Nonalcoholic fatty liver disease (NAFLD) is one of the aspects of metabolic syndrome (MetS). Due to the increase of MetS in Iran, this study was... 
Non-Alcoholic fatty liver disease (NAFLD) | URBAN-POPULATION | RISK-FACTORS | ADULT-POPULATION | ALANINE AMINOTRANSFERASE | Metabolic syndrome | NATURAL-HISTORY | Risk factors | METABOLIC-SYNDROME | OBESITY | IMPACT | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | STEATOHEPATITIS | HEPATIC STEATOSIS | Hepatitis | Obesity | Insulin resistance | Liver | Original
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8. Full Text Fatty liver index (FLI) and prediction of new cases of non-alcoholic fatty liver disease: A population-based study of northern Iran
by Motamed, Nima and Faraji, Amir Hossein and Khonsari, Mahmood Reza and Maadi, Mansooreh and Tameshkel, Fahimeh Safarnezhad and Keyvani, Hossein and Ajdarkosh, Hossein and Karbalaie Niya, Mohammad Hadi and Rezaie, Nader and Zamani, Farhad
Clinical Nutrition, ISSN 0261-5614, 2019
Background and aims: Non-alcoholic fatty liver disease is considered a major public health concern. The prediction of individuals who can acquire this disease... 
Non-alcoholic fatty liver disease | Fatty liver index | Prediction
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9. Full Text Prevalence and risk factors of hepatitis C virus infection in Amol city, north of Iran: A population-Based study (2008-2011)
by Zamani, Farhad and Sohrabi, Masoudreza and Poustchi, Hossein and Keyvani, Hossein and Saeedian, Fatemeh Sima and Ajdarkosh, Hossein and Khoonsari, Mahood and Hemmasi, Gholamreza and Moradilakeh, Maziar and Motamed, Nima and Maadi, Masoumeh
Hepatitis Monthly, ISSN 1735-143X, 12/2013, Volume 13, Issue 12, p. e13313
Background: Hepatitis C Virus (HCV) infection is one of the most important causes of chronic liver disease and related problems in the world. There are few... 
Polymerase chain reaction | Urban population | Epidemiology | Hepacivirus | Rural population | B-VIRUS | Rural Population | Polymerase Chain Reaction | HEMODIALYSIS-PATIENTS | BLOOD-DONORS | Urban Population | HUMAN-IMMUNODEFICIENCY-VIRUS | GASTROENTEROLOGY & HEPATOLOGY
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10. Full Text Comparison of Acyclovir and Multistrain Lactobacillus brevis in Women with Recurrent Genital Herpes Infections: a Double-Blind, Randomized, Controlled Study
by Mohseni, Amir Hossein and Mohseni, Amir Hossein and Taghinezhad-S, Sedigheh and Taghinezhad-S, Sedigheh and Keyvani, Hossein and Keyvani, Hossein and Ghobadi, Narges and Ghobadi, Narges
Probiotics and Antimicrobial Proteins, ISSN 1867-1306, 12/2018, Volume 10, Issue 4, pp. 740 - 747
We performed a randomized double-blind controlled trial to compare the efficacy and safety of multistrain probiotic and acyclovir in women patients with... 
Protein Science | Probiotic | Recurrence | Chemistry | Microbiology | Nutrition | Chemistry/Food Science, general | Lactobacillus brevis | Applied Microbiology | Acyclovir | HSV-2 | SIMPLEX-VIRUS TYPE-2 | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | RESISTANCE | ANTIVIRAL ACTIVITY | ANTIBODY | MICROBIOLOGY | PCR | Probiotics - administration & dosage | Virus Shedding - drug effects | Humans | Middle Aged | Acyclovir - adverse effects | Administration, Intravaginal | Antiviral Agents - administration & dosage | Herpes Genitalis - drug therapy | Young Adult | Antiviral Agents - adverse effects | Adolescent | Adult | Female | Herpesvirus 2, Human - physiology | Herpesvirus 2, Human - drug effects | Acyclovir - administration & dosage | Lactobacillus brevis - physiology | Women | Medical research | Herpes genitalis | Relapse | Gastrointestinal agents | Clinical trials | Medicine, Experimental | Comparative analysis | Health aspects | Diseases
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11. Full Text The Prevalence of Non-alcoholic Fatty Liver Disease and Diabetes Mellitus in an Iranian Population
by Rabiee, Behnam and Roozafzai, Farzin and Hemasi, Gholam Reza and Poustchi, Hossein and Keyvani, Hossein and Khonsari, Mahmood Reza and Ajdarkosh, Hossein and Maadi, Mansooreh and Sima Saeedian, Fatemeh and Zamani, Farhad
Middle East journal of digestive diseases, ISSN 2008-5230, 04/2017, Volume 9, Issue 2, pp. 86 - 93
BACKGROUND Type II diabetes mellitus (T2DM) and non-alcoholic fatty liver disease (NAFLD) are important causes of morbidity and mortality worldwide. We aimed... 
Non-communicable disease | Prevalence | Iran | Non-alcoholic fatty liver disease | Original | Diabetes mellitus
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12. Full Text A population based study on hepatitis B virus in Northern Iran, Amol
by Keyvani, Hossein and Sohrabi, Masoudreza and Zamani, Farhad and Poustchi, Hossein and Ashrafi, Hossein and Saeedian, Fatemeh and Mooadi, Mansooreh and Motamed, Nima and Ajdarkosh, Hossein and Khonsari, Mahmoodreza and Hemmasi, Gholamreza and Ameli, Mitra and Kabir, Ali and Khodadost, Mahmoud
Hepatitis Monthly, ISSN 1735-143X, 08/2014, Volume 14, Issue 8, p. e20540
Background: Viral hepatitis is a major health problem worldwide. Change in transmission patterns of hepatitis B makes it necessary to re-evaluate its... 
Infection | HBsAg | Prevalence | Hepatitis B virus | Epidemiology | Hepatitis B Virus | BLOOD-DONORS | SEROPREVALENCE | GENERAL-POPULATION | SEROEPIDEMIOLOGY | MASHHAD | GASTROENTEROLOGY & HEPATOLOGY | HBV INFECTION | BURDEN | ANTIGEN
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13. Full Text The effectiveness of sofosbuvir and daclatasvir in the treatment of hepatitis C in thalassaemia major patients and their effect on haematological factors
by Zamani, Farhad and Ajdarkosh, Hossein and Safarnezhad-Tameshkel, Fahimeh and Azarkeivan, Azita and Keyvani, Hossein and Naserifar, Farshad and Vafaeimanesh, Jamshid
Indian Journal of Medical Microbiology, ISSN 0255-0857, 04/2018, Volume 36, Issue 2, pp. 224 - 229
Context: Patients with thalassaemia arc at risk of infections such as hepatitis C virus (HCV) due to their repeated blood transfusions; meanwhile, the... 
sofosbuvir | hepatitis C virus | thalassaemia major | Anaemia | daclatasvir | VIRUS-INFECTION | HCV GENOTYPE 1 | PHASE-III | RIBAVIRIN | PREVALENCE | IMMUNOLOGY | COMBINATION | LEDIPASVIR | THERAPY | BETA-THALASSEMIA | ADVANCED LIVER-DISEASE | Infection | Antiviral agents | Medical research | Medicine, Experimental | Drug therapy | Hepatitis C virus | Health aspects | Blood transfusion | Blood transfusions | Substance abuse treatment | Transfusion | Disease | Liver | Ferritin | Clinical trials | Viruses | Infections | Iron | Blood | Hepatitis | Hemoglobin | Genotypes | Hematology | Anemia | Complications | Health risks | Thalassemia | Patients | Studies | Interferon | Hepatitis C
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14. Full Text Assessment of the Human Cytomegalovirus UL97 Gene for Identification of Resistance to Ganciclovir in Iranian Immunosuppressed Patients
by Keyvani, H and Saroukalaei, ST and Mohseni, AH
JUNDISHAPUR JOURNAL OF MICROBIOLOGY, ISSN 2008-3645, 05/2016, Volume 9, Issue 5, p. e31733
Background: Human cytomegalovirus (HCMV) infections are a major cause of morbidity and mortality among immunocompromised patients. Prolonged antiviral therapy... 
OPEN READING FRAME | ASSAY | PHOSPHORYLATION | MICROBIOLOGY | TRANSPLANT RECIPIENTS | CONFERS RESISTANCE | REAL-TIME PCR | Ganciclovir | Iran | DNA | DISEASE | Human Cytomegalovirus | UL97 Protein | MUTATIONS | ANTIVIRAL DRUGS
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15. Full Text Molecular evolution and phylodynamics of hepatitis B virus infection circulating in Iran
by Mozhgani, Sayed-Hamidreza and Malekpour, Seyed Amir and Norouzi, Mehdi and Ramezani, Fatemeh and Rezaee, Seyed Abdolrahim and Poortahmasebi, Vahdat and Sadeghi, Mehdi and Alavian, Seyed Moayed and Zarei-Ghobadi, Mohadeseh and Ghaziasadi, Azam and Karimzadeh, Hadi and Malekzadeh, Reza and Ziaee, Masood and Abedi, Farshid and Ataei, Behrooz and Yaran, Majid and Sayad, Babak and Jahantigh, Hamid Reza and Somi, Mohammad hossein and Sarizadeh, Gholamreza and Sanei-Moghaddam, Ismail and Mansour-Ghanaei, Fariborz and Keyvani, Hossein and Kalantari, Ebrahim and Fakhari, Zahra and Geravand, Babak and Jazayeri, Seyed Mohammad
Archives of Virology, ISSN 0304-8608, 6/2018, Volume 163, Issue 6, pp. 1479 - 1488
Previous local and national Iranian publications indicate that all Iranian hepatitis B virus (HBV) strains belong to HBV genotype D. The aim of this study was... 
Medical Microbiology | Infectious Diseases | Biomedicine | Virology | GENOTYPES | JMODELTEST | MAXIMUM-LIKELIHOOD | PHYLOGENIES | VIROLOGY | HBV | Hepatitis B virus | Evolutionary biology | Health aspects | Analysis | Hepatitis B | Molecular evolution | Genotype & phenotype | Hepatitis | Blood & organ donations | Vaccination | Evolution | Infections | Sampling | Bayesian analysis | Epidemiology | Genotypes
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16. Full Text Rural residency has a protective effect and marriage is a risk factor for NAFLD
by Motamed, Nima and Maadi, Mansooreh and Sohrabi, Masoudreza and Keyvani, Hossein and Poustchi, Hossein and Zamani, Farhad
Hepatitis Monthly, ISSN 1735-143X, 06/2016, Volume 16, Issue 7, p. e38357
Background: Non-alcoholic fatty liver disease (NAFLD) is considered the leading cause of liver disease worldwide. Although many previous studies have evaluated... 
Rural living | Marriage | NAFLD | MORTALITY | VITAMIN-D | POPULATION | FATTY LIVER-DISEASE | URBAN | NONALCOHOLIC STEATOHEPATITIS | Rural Living | PREVALENCE | GASTROENTEROLOGY & HEPATOLOGY | NORTHERN IRAN
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17. Full Text The Prevalence of HPV Genotypes in Iranian Population: An Update
by Mobini Kesheh, Mina and Keyvani, Hossein
Iranian Journal of Pathology, ISSN 1735-5303, 2019, Volume 14, Issue 3, pp. 197 - 205
INNO-LiPA HPV genotyping | Human papillomavirus (HPV) | Genotype distribution | Iran | Original | Age distribution
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18. Full Text Assessment of the human cytomegalovirus UL97 gene for immunosuppressedidentification of resistancepatientsto ganciclovir in Iranian
by Keyvani, Hossein and Saroukalaei, Sedigheh Taghinezhad and Mohseni, Amir Hossein
Jundishapur Journal of Microbiology, ISSN 2008-3645, 05/2016, Volume 9, Issue 5
UL97 protein | Ganciclovir | Iran | Human cytomegalovirus
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19. Full Text Protection against human papillomavirus type 16-induced tumors in C57BL/6 mice by mucosal vaccination with Lactococcus lactis NZ9000 expressing E6 oncoprotein
by Taghinezhad-S, Sedigheh and Mohseni, Amir Hossein and Keyvani, Hossein and Razavilar, Vadood
Microbial pathogenesis, 11/2018, Volume 126, p. 149
Recombinant strains of Lactococcus lactis NZ9000 that express native and codon-optimized E6 protein (fused to the SPusp45 secretion signal) were successfully... 
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20. Full Text Protection against human papillomavirus type 16-induced tumors in C57BL/6 mice by mucosal vaccination with Lactococcus lactis NZ9000 expressing E6 oncoprotein
by Taghinezhad-S, Sedigheh and Mohseni, Amir Hossein and Keyvani, Hossein and Razavilar, Vadood
Microbial Pathogenesis, ISSN 0882-4010, 01/2019, Volume 126, pp. 149 - 156
Recombinant strains of NZ9000 that express native and codon-optimized E6 protein (fused to the SPusp45 secretion signal) were successfully constructed by using... 
Lactococcus lactis | Protein secretion | Vaccine | pNZ8123 | Oral immunization | HPV | VIRUS | MICROBIOLOGY | ANTIGENS | INDUCTION | IMMUNOLOGY | DELIVERY | IMMUNIZATION | IMMUNE-RESPONSES | PROTEINS | VACCINES | Antigens | Codon | Lymphocytes | Analysis | Vaccination | Genes | Mice | Gene expression | Recombinant proteins | Cervical cancer | Tumors
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