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Journal Article
Journal Article
Diabetes, ISSN 0012-1797, 09/2006, Volume 55, Issue 9, pp. 2470 - 2478
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2005, Volume 115, Issue 6, pp. 1627 - 1635
Journal Article
Scientific Reports, ISSN 2045-2322, 2013, Volume 3, Issue 1, p. 2767
Myocardial ischemia, while causing cardiomyocyte injury, can activate innate protective processes, enhancing myocardial tolerance to ischemia. Such processes... 
BETA-KLOTHO | SURVIVAL | ENDOTHELIAL PROGENITOR CELLS | ARTERIAL ELASTIC LAMINAE | PPAR-ALPHA | ACTIVATION | MULTIDISCIPLINARY SCIENCES | REPERFUSION INJURY | BONE-MARROW | C-KIT | AKT | Up-Regulation | Liver - pathology | Phosphorylation | Cardiotonic Agents - metabolism | Adipose Tissue - physiopathology | Caspase 3 - metabolism | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | Glucuronidase | Liver - physiopathology | Phosphatidylinositol 3-Kinases | Myocardial Reperfusion Injury - enzymology | Myocytes, Cardiac - enzymology | Adipose Tissue - metabolism | Fibroblast Growth Factors - metabolism | Myocardial Reperfusion Injury - pathology | Endocrine System - metabolism | Myocardial Ischemia - physiopathology | bcl-Associated Death Protein - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Heart Function Tests | Heart Ventricles - pathology | Signal Transduction | Liver - metabolism | Adipose Tissue - pathology | Gene Silencing | Myocardial Ischemia - prevention & control | Myocardial Ischemia - enzymology | Myocardial Reperfusion Injury - physiopathology | Endocrine System - pathology | Myocardial Ischemia - pathology | Myocytes, Cardiac - pathology | Animals | Heart Ventricles - physiopathology | Protein Binding | Heart Ventricles - metabolism | Mice | Hemodynamics | RNA, Small Interfering - metabolism | Myocardial infarction | AKT1 protein | Adipose tissue | Liver | Caspase | Myocardial ischemia | Cardiomyocytes | Adipocytes | Caspase-3 | 1-Phosphatidylinositol 3-kinase | Membrane proteins | Reperfusion | Ischemia | Cell death | Klotho protein | Rodents | Myocardium | Fibroblast growth factor receptor 1
Journal Article
Molecular Metabolism, ISSN 2212-8778, 2013, Volume 3, Issue 3, pp. 221 - 229
Abstract Since the discovery of insulin in 1921, protein therapeutics have become vital tools in the treatment of diabetes mellitus. This heritage has been... 
Endocrinology & Metabolism | Drug discovery | Metabolism | LY2405319 | FGF21 | BETA-KLOTHO | ANTIDIABETIC ACTIONS | PPAR-ALPHA | FIBROBLAST-GROWTH-FACTOR-21 | INSULIN SENSITIVITY | INDUCED OBESE MICE | ENERGY-EXPENDITURE | ENDOCRINOLOGY & METABOLISM | EXPRESSION | GROWTH-FACTOR 21 | GLUCAGON
Journal Article
Diabetes, ISSN 0012-1797, 05/2013, Volume 62, Issue 5, pp. 1453 - 1463
Glucagon, an essential regulator of glucose homeostasis, also modulates lipid metabolism and promotes weight loss, as reflected by the wasting observed in... 
PPAR-ALPHA | BODY-WEIGHT | METABOLISM | FIBROBLAST-GROWTH-FACTOR-21 | PHARMACOLOGY | INCREASES ENERGY-EXPENDITURE | ENDOCRINOLOGY & METABOLISM | DEGRADATION | MICE | INSULIN SENSITIVITY | FGF21 | Obesity - drug therapy | Humans | Peptides - pharmacokinetics | Fibroblast Growth Factors - genetics | Male | Fibroblast Growth Factors - secretion | Obesity - blood | Anti-Obesity Agents - therapeutic use | Glucagon - agonists | Fibroblast Growth Factors - metabolism | Anti-Obesity Agents - pharmacokinetics | Peptides - chemical synthesis | Hepatocytes - secretion | Hypoglycemic Agents - therapeutic use | Receptors, Glucagon - agonists | Receptors, Glucagon - genetics | Hypoglycemic Agents - pharmacokinetics | Peptides - physiology | Rats | Hypoglycemic Agents - pharmacology | Mice, Knockout | Cross-Over Studies | Anti-Obesity Agents - chemical synthesis | Mice | Anti-Obesity Agents - pharmacology | Hepatocytes - pathology | Diabetes Mellitus, Type 2 - metabolism | Hepatocytes - metabolism | Molecular Targeted Therapy | Mice, Mutant Strains | HEK293 Cells | Adult | Female | Hepatocytes - drug effects | Recombinant Proteins - metabolism | Double-Blind Method | Cells, Cultured | Insulin Resistance | Receptors, Glucagon - metabolism | Recombinant Proteins - agonists | Glucagon - pharmacology | Obesity - metabolism | Diabetes Mellitus, Type 2 - blood | Animals | Fibroblast Growth Factors - blood | Hypoglycemic Agents - chemical synthesis | Glucagon - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Peptides - therapeutic use | Physiological aspects | Fibroblast growth factors | Research | Glucagon | Analysis | Original Research
Journal Article