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1. Full Text The New 2018 Cholesterol Guidelines: Filling Gaps and Expanding Opportunities
by Khera, Amit
Circulation, ISSN 0009-7322, 06/2019, Volume 139, Issue 25, pp. 2805 - 2808
cholesterol | PERIPHERAL VASCULAR DISEASE | CARDIAC & CARDIOVASCULAR SYSTEMS | guidelines as topic
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2. Full Text The New 2018 Cholesterol Guidelines
by Khera, Amit
Circulation, 06/2019, Volume 139, Issue 25, pp. 2805 - 2808
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3. Full Text Reply
by Khera, Amit
Journal of the American College of Cardiology, ISSN 0735-1097, 02/2013, Volume 61, Issue 5, p. 597
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4. Full Text Reply
by Khera, Amit
Journal of the American College of Cardiology, ISSN 0735-1097, 02/2013, Volume 61, Issue 5, pp. 597 - 597
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5. Full Text Reply
by Khera, Amit
Journal of the American College of Cardiology, ISSN 0735-1097, 02/2013, Volume 61, Issue 5, p. 597
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6. Full Text Reply
by Amit Khera
Journal of the American College of Cardiology, ISSN 0735-1097, 02/2013, Volume 61, Issue 5, p. 597
  [...]we repeated our analyses using sex-specific tertiles of body fat percentage measured by DXA rather than BMI categories and found essentially the same... 
Obesity | Weight control | Body fat
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7. Full Text Reply
by Khera, Amit
Journal of the American College of Cardiology, ISSN 0735-1097, 02/2013, Volume 61, Issue 5, p. 597
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8. Full Text Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia
by Khera, Amit V., MD and Won, Hong-Hee, PhD and Peloso, Gina M., PhD and Lawson, Kim S., MS and Bartz, Traci M., MS and Deng, Xuan, MSc and van Leeuwen, Elisabeth M and Natarajan, Pradeep, MD, MMSc and Emdin, Connor A., HBSc and Bick, Alexander G., PhD and Morrison, Alanna C., PhD and Brody, Jennifer A., BA and Gupta, Namrata, PhD and Nomura, Akihiro, MD and Kessler, Thorsten, MD and Duga, Stefano, PhD and Bis, Joshua C., PhD and van Duijn, Cornelia M., PhD and Cupples, L. Adrienne, PhD and Psaty, Bruce, MD, PhD and Rader, Daniel J., MD and Danesh, John, DPhil and Schunkert, Heribert, MD and McPherson, Ruth, MD and Farrall, Martin, MD and Watkins, Hugh, MD, PhD and Lander, Eric, PhD and Wilson, James G., MD and Correa, Adolfo, MD, PhD and Boerwinkle, Eric, PhD and Merlini, Piera Angelica, MD and Ardissino, Diego, MD and Saleheen, Danish, MBBS, PhD and Gabriel, Stacey, PhD and Kathiresan, Sekar, MD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 67, Issue 22, pp. 2578 - 2589
Abstract Background Approximately 7% of American adults have severe hypercholesterolemia (untreated low-density lipoprotein [LDL] cholesterol ≥190 mg/dl),... 
Cardiovascular | Internal Medicine | coronary artery disease | gene sequencing | genetics | low-density lipoprotein cholesterol | POPULATION | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | MYOCARDIAL-INFARCTION | RANDOMIZED-TRIALS | AUTOSOMAL-DOMINANT HYPERCHOLESTEROLEMIA | RISK | MUTATION DETECTION RATE | CORONARY-HEART-DISEASE | ASSOCIATION | PARTICIPANTS | Receptors, LDL - genetics | Humans | Middle Aged | Hyperlipoproteinemia Type II - diagnosis | Male | Proprotein Convertase 9 - genetics | Apolipoprotein B-100 - genetics | Case-Control Studies | Genetic Variation | Cholesterol, LDL - blood | Female | Heterozygote | Coronary Artery Disease - epidemiology | Sequence Analysis | Cohort Studies | Hypercholesterolemia - epidemiology | Hyperlipoproteinemia Type II - genetics | Medical colleges | Care and treatment | Low density lipoproteins | Genes | Coronary heart disease | Population genetics | Epidemiology | Blood | Hypercholesterolemia | Analysis and chemistry | Atherosclerosis | Genetic research | Genetic aspects | Diagnosis | Research institutes | Cardiology | Trans fatty acids | Heart attacks | Cardiovascular disease | Lipids | Apolipoproteins | Low density lipoprotein | Cholesterol | Proteins | Studies | Confidence intervals | Consortia | Algorithms | Coronary vessels | Population | Mutation | Deoxyribonucleic acid--DNA | Index Medicus | Abridged Index Medicus
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9. Full Text What's a Malignant Family History?
by Khera, Amit and Joshi, Parag
JACC: Cardiovascular Imaging, ISSN 1936-878X, 10/2017, Volume 10, Issue 10, p. 1136
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10. Full Text What's a Malignant Family History?: You'll Know It When You See It
by Khera, Amit and Joshi, Parag
JACC: Cardiovascular Imaging, ISSN 1936-878X, 10/2017, Volume 10, Issue 10, pp. 1136 - 1138
atherosclerosis | coronary artery disease | atherosclerotic | plaque | genetic predisposition to disease | multidetector computed tomography | Heart | Coronary Artery Disease | Plaque, Atherosclerotic | Humans | Index Medicus
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11. Full Text What’s a Malignant Family History?: You’ll Know It When You See It
by Khera, Amit and Joshi, Parag
JACC: Cardiovascular Imaging, ISSN 1936-878X, 10/2017, Volume 10, Issue 10, pp. 1136 - 1138
atherosclerosis | coronary artery disease | atherosclerotic | plaque | multidetector computed tomography | genetic predisposition to disease
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12. Full Text The Addition of Niacin to Statin Therapy Improves High-Density Lipoprotein Cholesterol Levels But Not Metrics of Functionality
by Khera, Amit V., MD and Patel, Parin J., MD and Reilly, Muredach P., MD and Rader, Daniel J., MD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2013, Volume 62, Issue 20, pp. 1909 - 1910
  To the Editor: The role of niacin in the era of widespread statin use has been called into question by 2 recent clinical trials, AIM-HIGH (Atherothrombosis... 
Cardiovascular | Internal Medicine | CAPACITY | CARDIAC & CARDIOVASCULAR SYSTEMS | EFFLUX | Simvastatin - therapeutic use | Niacin - therapeutic use | Carotid Artery Diseases - blood | Humans | Cholesterol, HDL - blood | Female | Male | Aged | Clinical Trials as Topic | Hypolipidemic Agents - therapeutic use | Carotid Artery Diseases - drug therapy | Randomized Controlled Trials as Topic | Niacin | Cholesterol | Statins | Confidence intervals | Plasma | Lipoproteins | Vitamin B | Atherosclerosis | Clinical trials | Cardiovascular disease | Triglycerides | Acute coronary syndromes | Apolipoproteins | Index Medicus | Abridged Index Medicus
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13. Full Text HDL Cholesterol Efflux Capacity and Incident Cardiovascular Events
by Rohatgi, Anand and Khera, Amit and Berry, Jarett D and Givens, Edward G and Ayers, Colby R and Wedin, Kyle E and Neeland, Ian J and Yuhanna, Ivan S and Rader, Daniel R and de Lemos, James A and Shaul, Philip W
The New England Journal of Medicine, ISSN 0028-4793, 12/2014, Volume 371, Issue 25, pp. 2383 - 2393
The ability of HDL to accept cholesterol from macrophages (cholesterol efflux capacity) is a key part of reverse cholesterol transport. In nearly 3000 adults,... 
ATHEROSCLEROSIS | MEDICINE, GENERAL & INTERNAL | DENSITY-LIPOPROTEIN CHOLESTEROL | ABCG1(-/-) BONE-MARROW | HIGH-RISK | ABILITY | Biomarkers - metabolism | Cardiovascular Diseases - metabolism | Follow-Up Studies | Lipoproteins, HDL - blood | Humans | Middle Aged | Risk Factors | Lipoproteins, HDL - metabolism | Male | Atherosclerosis - epidemiology | Atherosclerosis - metabolism | Incidence | Biological Transport | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Adult | Cholesterol, LDL - blood | Female | Diagnosis | Cardiovascular diseases | Cholesterol, HDL | Analysis | Risk factors | Myocardial infarction | Cerebral infarction | Cardiovascular disease | Population studies | Macrophages | Reclassification | Epidemiology | Cholesterol | Lipoproteins | Arteriosclerosis | Lipoproteins (high density) | Index Medicus | Abridged Index Medicus
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14. Full Text ANGPTL3 Deficiency and Protection Against Coronary Artery Disease
by Stitziel, Nathan O., MD, PhD and Khera, Amit V., MD and Wang, Xiao, PhD and Bierhals, Andrew J., MD, MPH and Vourakis, A. Christina, BA and Sperry, Alexandra E., BA and Natarajan, Pradeep, MD and Klarin, Derek, MD and Emdin, Connor A., DPhil and Zekavat, Seyedeh M., BSc and Nomura, Akihiro, MD and Erdmann, Jeanette, PhD and Schunkert, Heribert, MD and Samani, Nilesh J., MD and Kraus, William E., MD and Shah, Svati H., MD, MPH and Yu, Bing, PhD and Boerwinkle, Eric, PhD and Rader, Daniel J., MD and Gupta, Namrata, PhD and Frossard, Philippe M., PhD and Rasheed, Asif, MBBS and Danesh, John, DPhil and Lander, Eric S., PhD and Gabriel, Stacey, PhD and Saleheen, Danish, MBBS, PhD and Musunuru, Kiran, MD, PhD, MPH and Kathiresan, Sekar, MD and PROMIS Myocardial Infarction Genet and PROMIS and Myocardial Infarction Genetics Consortium Investigators
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2017, Volume 69, Issue 16, pp. 2054 - 2063
Abstract Background Familial combined hypolipidemia, a Mendelian condition characterized by substantial reductions in all 3 major lipid fractions, is caused by... 
Cardiovascular | Internal Medicine | human genetics | loss-of-function mutations | myocardial infarction | CARDIAC & CARDIOVASCULAR SYSTEMS | VARIANTS | CHOLESTEROL | ATHEROSCLEROSIS | RISK | TRIGLYCERIDES | OF-FUNCTION MUTATIONS | PLASMA-LIPIDS | GENE | ASSOCIATION | FAMILIAL COMBINED HYPOLIPIDEMIA | Myocardial Infarction - blood | Atherosclerosis - genetics | Humans | Mice, Inbred C57BL | Middle Aged | Risk Factors | Angiopoietins - deficiency | Male | Mutation, Missense | Angiopoietins - blood | Case-Control Studies | Mice, Knockout | Animals | Angiopoietin-like Proteins | Lipids - blood | Coronary Artery Disease - genetics | Adult | Female | Angiopoietins - genetics | Medical colleges | Genomics | Research institutes | Cardiology | Population genetics | Coronary heart disease | Cardiovascular agents | Analysis | Myocardial infarction | Angiography | Angiopoietin | Health risks | Coronary artery | Cardiovascular disease | Population studies | Triglycerides | Coronary artery disease | Low density lipoprotein | Cholesterol | Confidence intervals | Reduction | Computed tomography | Rodents | Arteriosclerosis | Atherosclerosis | Biomarkers | Infarction | Mutation | Health risk assessment | Heart diseases | Carrier density | Index Medicus | Abridged Index Medicus | loss of function mutations
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15. Full Text Reply
by Khera, Amit V and Kathiresan, Sekar
Journal of the American College of Cardiology, ISSN 0735-1097, 02/2017, Volume 69, Issue 6, p. 755
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16. Full Text Reply
: Familial Hypercholesterolemia: Independent Malignity andLDLRVariant Databases
by Amit V Khera and Sekar Kathiresan
Journal of the American College of Cardiology, ISSN 0735-1097, 02/2017, Volume 69, Issue 6, p. 755
  With regard to familial hypercholesterolemia, several approaches can aid in pathogenicity determination: computer prediction algorithms, in vivo or in vitro... 
Cardiovascular disease | Mutation | Low density lipoprotein | Cholesterol
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17. Full Text To the editor
by Khera, Amit V and Kathiresan, Sekar
New England Journal of Medicine, ISSN 0028-4793, 02/2017, Volume 376, Issue 5, pp. 498 - 499
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18. Full Text The Anti-Oxidative Capacity of High-Density Lipoprotein Is Reduced in Acute Coronary Syndrome But Not in Stable Coronary Artery Disease
by Patel, Parin J., MD and Khera, Amit V., MD and Jafri, Kashif, BA and Wilensky, Robert L., MD and Rader, Daniel J., MD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2011, Volume 58, Issue 20, pp. 2068 - 2075
Objectives This study examined an anti-inflammatory property of high-density lipoprotein (HDL) in subjects with acute coronary syndrome (ACS) and stable... 
Cardiovascular | Internal Medicine | coronary artery disease | HDL function | HDL inflammatory index | oxidized LDL | acute coronary syndrome(s) | RHEUMATOID-ARTHRITIS | FRACTIONAL ESTERIFICATION RATE | OXIDATIVE STRESS | METABOLIC SYNDROME | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | ENDOTHELIAL FUNCTION | HEART-DISEASE | HDL-CHOLESTEROL | TRANSFER PROTEIN GENE | ATHEROGENIC INDEX | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Acute Coronary Syndrome - metabolism | Lipoproteins, HDL - drug effects | Coronary Artery Disease - metabolism | Humans | Middle Aged | Risk Factors | Lipoproteins, HDL - metabolism | Female | Male | Aged | Case-Control Studies | Medical colleges | Coronary heart disease | Low density lipoproteins | Medical students | Cardiovascular agents | Confidence intervals | Lipoproteins | Heart attacks | Coronary vessels | Colleges & universities | Atherosclerosis | Cardiovascular disease | Triglycerides | Intubation | Acute coronary syndromes | Cholesterol | Chronic illnesses | Index Medicus | Abridged Index Medicus
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19. Full Text Reply
by Khera, Amit V and Kathiresan, Sekar
Journal of the American College of Cardiology, ISSN 0735-1097, 02/2017, Volume 69, Issue 6, p. 755
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20. Full Text Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes
by Gusarova, Viktoria and O'Dushlaine, Colm and Teslovich, Tanya M and Benotti, Peter N and Mirshahi, Tooraj and Gottesman, Omri and Van Hout, Cristopher V and Murray, Michael F and Mahajan, Anubha and Nielsen, Jonas B and Fritsche, Lars and Wulff, Anders Berg and Gudbjartsson, Daniel F and Sjögren, Marketa and Emdin, Connor A and Scott, Robert A and Lee, Wen-Jane and Small, Aeron and Kwee, Lydia C and Dwivedi, Om Prakash and Prasad, Rashmi B and Bruse, Shannon and Lopez, Alexander E and Penn, John and Marcketta, Anthony and Leader, Joseph B and Still, Christopher D and Kirchner, H. Lester and Mirshahi, Uyenlinh L and Wardeh, Amr H and Hartle, Cassandra M and Habegger, Lukas and Fetterolf, Samantha N and Tusie-Luna, Teresa and Morris, Andrew P and Holm, Hilma and Steinthorsdottir, Valgerdur and Sulem, Patrick and Thorsteinsdottir, Unnur and Rotter, Jerome I and Chuang, Lee-Ming and Damrauer, Scott and Birtwell, David and Brummett, Chad M and Khera, Amit V and Natarajan, Pradeep and Orho-Melander, Marju and Flannick, Jason and Lotta, Luca A and Willer, Cristen J and Holmen, Oddgeir L and Ritchie, Marylyn D and Ledbetter, David H and Murphy, Andrew J and Borecki, Ingrid B and Reid, Jeffrey G and Overton, John D and Hansson, Ola and Groop, Leif and Shah, Svati H and Kraus, William E and Rader, Daniel J and Chen, Yii-Der I and Hveem, Kristian and Wareham, Nicholas J and Kathiresan, Sekar and Melander, Olle and Stefansson, Kari and Nordestgaard, Børge G and Tybjærg-Hansen, Anne and Abecasis, Goncalo R and Altshuler, David and Florez, Jose C and Boehnke, Michael and McCarthy, Mark I and Yancopoulos, George D and Carey, David J and Shuldiner, Alan R and Baras, Aris and Dewey, Frederick E and Gromada, Jesper and Diabetes - Cardiovascular Disease and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Diabetes - kardiovaskulär sjukdom and Lund University and Genomics, Diabetes and Endocrinology and EpiHealth: Epidemiology for Health and Genomik, diabetes och endokrinologi and Institutionen för kliniska vetenskaper, Malmö and Lunds universitet and Department of Clinical Sciences, Malmö
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2252 - 11
Angiopoietin-like 4 (ANGPTL4) is an endogenous inhibitor of lipoprotein lipase that modulates lipid levels, coronary atherosclerosis risk, and nutrient... 
HEART-DISEASE | REMNANT CHOLESTEROL | PLASMA-LIPIDS | MULTIDISCIPLINARY SCIENCES | MICE | ANGIOPOIETIN-LIKE PROTEIN-4 | LIPOPROTEIN-LIPASE | HAN CHINESE | CHINESE POPULATION | GENOME-WIDE ASSOCIATION | ADIPOSE-TISSUE | Diabetes Mellitus, Type 2 - genetics | Humans | Homeostasis | Male | Diabetes Mellitus, Type 2 - metabolism | Case-Control Studies | Genetic Variation | Diabetes Mellitus, Type 2 - etiology | Female | Lipoprotein Lipase - metabolism | Genetic Association Studies | Mice, Inbred C57BL | Risk Factors | Gene Silencing | Angiopoietin-like 4 Protein - deficiency | Mice, Knockout | Whole Exome Sequencing | Animals | Insulin Resistance - genetics | Angiopoietin-like 4 Protein - metabolism | Heterozygote | Mice | Blood Glucose - metabolism | Amino Acid Substitution | Angiopoietin-like 4 Protein - genetics | Deactivation | Angiopoietin | Diabetes mellitus | Health risks | Risk reduction | Risk | Lipoprotein lipase | Glucose | Lipase | Inactivation | Insulin | Proteins | Confidence intervals | Sensitivity | Nutrient loss | Rodents | Arteriosclerosis | Atherosclerosis | Genetics | Diabetes | Diabetes mellitus (non-insulin dependent) | Index Medicus | Medicinsk genetik | Basic Medicine | Medical Genetics | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin | Endocrinology and Diabetes
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