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1. Full Text Genetics of coronary artery disease: Discovery, biology and clinical translation
by Khera, Amit V and Kathiresan, Sekar
Nature reviews. Genetics, ISSN 1471-0056, 06/2017, Volume 18, Issue 6, pp. 331 - 344
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Animals | Coronary Artery Disease - therapy | Coronary Artery Disease - physiopathology | Humans | Translational Medical Research | Coronary Artery Disease - genetics | Precision Medicine | Genotype | Genetic aspects | Health aspects | Coronary heart disease | Risk factors | Index Medicus
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2. Full Text Mendelian Randomization
by Emdin, Connor A and Khera, Amit V and Kathiresan, Sekar
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 11/2017, Volume 318, Issue 19, pp. 1925 - 1926
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Clinical trials | Research | Comparative analysis | Genetic variation | Genetic variance | Randomization | Genetics | Meiosis | Epidemiology | Population genetics | Risk factors | Index Medicus | Abridged Index Medicus
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3. Full Text ASPC President’s message: The work must go on
by Khera, Amit
American Journal of Preventive Cardiology, ISSN 2666-6677, 06/2020, Volume 2
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4. Full Text ASPC President’s message: The birth of a new journal and major step forward for preventive cardiology
by Khera, Amit
American Journal of Preventive Cardiology, ISSN 2666-6677, 03/2020, Volume 1
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5. Full Text Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia
by Khera, Amit V., MD and Won, Hong-Hee, PhD and Peloso, Gina M., PhD and Lawson, Kim S., MS and Bartz, Traci M., MS and Deng, Xuan, MSc and van Leeuwen, Elisabeth M and Natarajan, Pradeep, MD, MMSc and Emdin, Connor A., HBSc and Bick, Alexander G., PhD and Morrison, Alanna C., PhD and Brody, Jennifer A., BA and Gupta, Namrata, PhD and Nomura, Akihiro, MD and Kessler, Thorsten, MD and Duga, Stefano, PhD and Bis, Joshua C., PhD and van Duijn, Cornelia M., PhD and Cupples, L. Adrienne, PhD and Psaty, Bruce, MD, PhD and Rader, Daniel J., MD and Danesh, John, DPhil and Schunkert, Heribert, MD and McPherson, Ruth, MD and Farrall, Martin, MD and Watkins, Hugh, MD, PhD and Lander, Eric, PhD and Wilson, James G., MD and Correa, Adolfo, MD, PhD and Boerwinkle, Eric, PhD and Merlini, Piera Angelica, MD and Ardissino, Diego, MD and Saleheen, Danish, MBBS, PhD and Gabriel, Stacey, PhD and Kathiresan, Sekar, MD
Journal of the American College of Cardiology, ISSN 0735-1097, 2016, Volume 67, Issue 22, pp. 2578 - 2589
Cardiovascular | Internal Medicine | coronary artery disease | gene sequencing | genetics | low-density lipoprotein cholesterol | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Receptors, LDL - genetics | Humans | Middle Aged | Hyperlipoproteinemia Type II - diagnosis | Male | Proprotein Convertase 9 - genetics | Apolipoprotein B-100 - genetics | Case-Control Studies | Genetic Variation | Cholesterol, LDL - blood | Female | Heterozygote | Coronary Artery Disease - epidemiology | Sequence Analysis | Cohort Studies | Hypercholesterolemia - epidemiology | Hyperlipoproteinemia Type II - genetics | Medical colleges | Care and treatment | Low density lipoproteins | Genes | Coronary heart disease | Population genetics | Epidemiology | Blood | Hypercholesterolemia | Analysis and chemistry | Atherosclerosis | Genetic research | Genetic aspects | Diagnosis | Research institutes | Cardiology | Trans fatty acids | Heart attacks | Cardiovascular disease | Lipids | Apolipoproteins | Low density lipoprotein | Cholesterol | Proteins | Studies | Confidence intervals | Consortia | Algorithms | Coronary vessels | Population | Mutation | Deoxyribonucleic acid--DNA | Index Medicus | Abridged Index Medicus
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6. Full Text HDL Cholesterol Efflux Capacity and Incident Cardiovascular Events
by Rohatgi, Anand and Khera, Amit and Berry, Jarett D and Givens, Edward G and Ayers, Colby R and Wedin, Kyle E and Neeland, Ian J and Yuhanna, Ivan S and Rader, Daniel R and de Lemos, James A and Shaul, Philip W
The New England journal of medicine, ISSN 0028-4793, 12/2014, Volume 371, Issue 25, pp. 2383 - 2393
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Biomarkers - metabolism | Cardiovascular Diseases - metabolism | Follow-Up Studies | Lipoproteins, HDL - blood | Humans | Middle Aged | Risk Factors | Lipoproteins, HDL - metabolism | Male | Atherosclerosis - epidemiology | Atherosclerosis - metabolism | Incidence | Biological Transport | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Adult | Cholesterol, LDL - blood | Female | Diagnosis | Cardiovascular diseases | Cholesterol, HDL | Analysis | Risk factors | Myocardial infarction | Cerebral infarction | Cardiovascular disease | Population studies | Macrophages | Reclassification | Epidemiology | Cholesterol | Lipoproteins | Arteriosclerosis | Lipoproteins (high density) | Index Medicus | Abridged Index Medicus
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7. Full Text Genetic Association of Waist-to-Hip Ratio With Cardiometabolic Traits, Type 2 Diabetes, and Coronary Heart Disease
by Emdin, Connor A and Khera, Amit V and Natarajan, Pradeep and Klarin, Derek and Zekavat, Seyedeh M and Hsiao, Allan J and Kathiresan, Sekar
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 02/2017, Volume 317, Issue 6, pp. 626 - 634
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Body Mass Index | Coronary Disease - blood | Blood Glucose - analysis | Cross-Sectional Studies | Blood Pressure - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Male | Case-Control Studies | Diabetes Mellitus, Type 2 - blood | Coronary Disease - genetics | Mendelian Randomization Analysis | Triglycerides - blood | Blood Glucose - genetics | Female | Polymorphism, Single Nucleotide | Obesity, Abdominal - genetics | Odds Ratio | Waist-Hip Ratio | Studies | Cardiovascular disease | Blood pressure | Statistical analysis | Diabetes | Index Medicus | Abridged Index Medicus
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8. Full Text Reply
by Amit Khera
Journal of the American College of Cardiology, ISSN 0735-1097, 02/2013, Volume 61, Issue 5, p. 597
Obesity | Weight control | Body fat
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9. Full Text Reply
by Khera, Amit
Journal of the American College of Cardiology, ISSN 0735-1097, 02/2013, Volume 61, Issue 5, p. 597
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10. Full Text Reply
by Khera, Amit
Journal of the American College of Cardiology, ISSN 0735-1097, 02/2013, Volume 61, Issue 5, p. 597
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11. Full Text Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes
by Gusarova, Viktoria and O'Dushlaine, Colm and Teslovich, Tanya M and Benotti, Peter N and Mirshahi, Tooraj and Gottesman, Omri and Van Hout, Cristopher V and Murray, Michael F and Mahajan, Anubha and Nielsen, Jonas B and Fritsche, Lars and Wulff, Anders Berg and Gudbjartsson, Daniel F and Sjögren, Marketa and Emdin, Connor A and Scott, Robert A and Lee, Wen-Jane and Small, Aeron and Kwee, Lydia C and Dwivedi, Om Prakash and Prasad, Rashmi B and Bruse, Shannon and Lopez, Alexander E and Penn, John and Marcketta, Anthony and Leader, Joseph B and Still, Christopher D and Kirchner, H. Lester and Mirshahi, Uyenlinh L and Wardeh, Amr H and Hartle, Cassandra M and Habegger, Lukas and Fetterolf, Samantha N and Tusie-Luna, Teresa and Morris, Andrew P and Holm, Hilma and Steinthorsdottir, Valgerdur and Sulem, Patrick and Thorsteinsdottir, Unnur and Rotter, Jerome I and Chuang, Lee-Ming and Damrauer, Scott and Birtwell, David and Brummett, Chad M and Khera, Amit V and Natarajan, Pradeep and Orho-Melander, Marju and Flannick, Jason and Lotta, Luca A and Willer, Cristen J and Holmen, Oddgeir L and Ritchie, Marylyn D and Ledbetter, David H and Murphy, Andrew J and Borecki, Ingrid B and Reid, Jeffrey G and Overton, John D and Hansson, Ola and Groop, Leif and Shah, Svati H and Kraus, William E and Rader, Daniel J and Chen, Yii-Der I and Hveem, Kristian and Wareham, Nicholas J and Kathiresan, Sekar and Melander, Olle and Stefansson, Kari and Nordestgaard, Børge G and Tybjærg-Hansen, Anne and Abecasis, Goncalo R and Altshuler, David and Florez, Jose C and Boehnke, Michael and McCarthy, Mark I and Yancopoulos, George D and Carey, David J and Shuldiner, Alan R and Baras, Aris and Dewey, Frederick E and Gromada, Jesper
Nature communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2252 - 11
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Diabetes Mellitus, Type 2 - genetics | Humans | Homeostasis | Male | Diabetes Mellitus, Type 2 - metabolism | Case-Control Studies | Genetic Variation | Diabetes Mellitus, Type 2 - etiology | Female | Lipoprotein Lipase - metabolism | Genetic Association Studies | Mice, Inbred C57BL | Risk Factors | Gene Silencing | Angiopoietin-like 4 Protein - deficiency | Mice, Knockout | Whole Exome Sequencing | Animals | Insulin Resistance - genetics | Angiopoietin-like 4 Protein - metabolism | Heterozygote | Mice | Blood Glucose - metabolism | Amino Acid Substitution | Angiopoietin-like 4 Protein - genetics | Deactivation | Angiopoietin | Diabetes mellitus | Health risks | Risk reduction | Risk | Lipoprotein lipase | Glucose | Lipase | Inactivation | Insulin | Proteins | Confidence intervals | Sensitivity | Nutrient loss | Rodents | Arteriosclerosis | Atherosclerosis | Genetics | Diabetes | Diabetes mellitus (non-insulin dependent) | Index Medicus | Medicinsk genetik | Basic Medicine | Medical Genetics | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin | Endocrinology and Diabetes
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12. Full Text ANGPTL3 Deficiency and Protection Against Coronary Artery Disease
by Stitziel, Nathan O., MD, PhD and Khera, Amit V., MD and Wang, Xiao, PhD and Bierhals, Andrew J., MD, MPH and Vourakis, A. Christina, BA and Sperry, Alexandra E., BA and Natarajan, Pradeep, MD and Klarin, Derek, MD and Emdin, Connor A., DPhil and Zekavat, Seyedeh M., BSc and Nomura, Akihiro, MD and Erdmann, Jeanette, PhD and Schunkert, Heribert, MD and Samani, Nilesh J., MD and Kraus, William E., MD and Shah, Svati H., MD, MPH and Yu, Bing, PhD and Boerwinkle, Eric, PhD and Rader, Daniel J., MD and Gupta, Namrata, PhD and Frossard, Philippe M., PhD and Rasheed, Asif, MBBS and Danesh, John, DPhil and Lander, Eric S., PhD and Gabriel, Stacey, PhD and Saleheen, Danish, MBBS, PhD and Musunuru, Kiran, MD, PhD, MPH and Kathiresan, Sekar, MD and PROMIS and Myocardial Infarction Genetics Consortium Investigators and PROMIS Myocardial Infarction Genet
Journal of the American College of Cardiology, ISSN 0735-1097, 2017, Volume 69, Issue 16, pp. 2054 - 2063
Cardiovascular | Internal Medicine | human genetics | loss-of-function mutations | myocardial infarction | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Myocardial Infarction - blood | Atherosclerosis - genetics | Humans | Mice, Inbred C57BL | Middle Aged | Risk Factors | Angiopoietins - deficiency | Male | Mutation, Missense | Angiopoietins - blood | Case-Control Studies | Mice, Knockout | Animals | Angiopoietin-like Proteins | Lipids - blood | Coronary Artery Disease - genetics | Adult | Female | Angiopoietins - genetics | Medical colleges | Genomics | Research institutes | Cardiology | Population genetics | Coronary heart disease | Cardiovascular agents | Analysis | Myocardial infarction | Angiography | Angiopoietin | Health risks | Coronary artery | Cardiovascular disease | Population studies | Triglycerides | Coronary artery disease | Low density lipoprotein | Cholesterol | Confidence intervals | Reduction | Computed tomography | Rodents | Arteriosclerosis | Atherosclerosis | Biomarkers | Infarction | Mutation | Health risk assessment | Heart diseases | Carrier density | Index Medicus | Abridged Index Medicus | loss of function mutations
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13. Full Text Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood
by Khera, Amit V and Chaffin, Mark and Wade, Kaitlin H and Zahid, Sohail and Brancale, Joseph and Xia, Rui and Distefano, Marina and Senol-Cosar, Ozlem and Haas, Mary E and Bick, Alexander and Aragam, Krishna G and Lander, Eric S and Smith, George Davey and Mason-Suares, Heather and Fornage, Myriam and Lebo, Matthew and Timpson, Nicholas J and Kaplan, Lee M and Kathiresan, Sekar
Cell (Cambridge), ISSN 0092-8674, 04/2019, Volume 177, Issue 3, pp. 587 - 596.e9
melanocortin 4 receptor | human genetics | genomic medicine | body mass index | weight | severe obesity | UK Biobank | polygenic score | genetic risk prediction | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Body Mass Index | Severity of Illness Index | Multifactorial Inheritance - genetics | Genome-Wide Association Study | Body Weight | Humans | Middle Aged | Risk Factors | Male | Obesity - genetics | Obesity - pathology | Adolescent | Female | Child | Longitudinal Studies | Infant, Newborn | Databases, Factual | Obesity | Genetic aspects | Health aspects | Genomics | Risk factors | World health | Index Medicus
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