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Pain, ISSN 0304-3959, 2011, Volume 152, Issue 6, pp. 1238 - 1248
Journal Article
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, ISSN 0893-133X, 10/2014, Volume 39, Issue 11, pp. 2694 - 2705
Journal Article
Biological Psychiatry, ISSN 0006-3223, 2015, Volume 79, Issue 11, pp. 917 - 927
Abstract Background GPR88 is an orphan G protein coupled receptor highly enriched in the striatum, and previous studies have focused on GPR88 function in... 
Psychiatry | Ethological scoring of anxiety | GPR88 agonist-induced GTPγS binding | Gene clustering | Medium spiny neurons | Psychiatric disorders | Spatial learning | CENTRAL EXTENDED AMYGDALA | PSYCHIATRY | DEPENDENT BEHAVIORS | PROTRACTED ABSTINENCE | NEUROSCIENCES | ADENOSINE A(2A) RECEPTORS | GPR88 agonist-induced GTP gamma S binding | C-TERMINAL DOMAINS | STRIATOPALLIDAL NEURONS | DORSAL STRIATUM | SELECTIVE INTERACTIONS | OBJECT RECOGNITION | PARKINSON-DISEASE | Naltrexone - analogs & derivatives | Receptors, Opioid, delta - metabolism | Dendrites - pathology | Male | Anxiety - drug therapy | Corpus Striatum - metabolism | Spatial Learning - physiology | Naltrexone - pharmacology | Female | Anxiety - metabolism | Corpus Striatum - pathology | Dopamine - metabolism | Dendrites - drug effects | Dendrites - metabolism | Movement Disorders - pathology | Receptors, Opioid, mu - metabolism | Mice, Inbred C57BL | Spatial Learning - drug effects | Amygdala - metabolism | Hippocampus - pathology | Amygdala - pathology | Anxiety - pathology | Mice, Knockout | Hippocampus - metabolism | Movement Disorders - metabolism | Animals | Receptors, G-Protein-Coupled - deficiency | Narcotic Antagonists - pharmacology | Serotonin - metabolism | Receptors, G-Protein-Coupled - genetics | Movement Disorders - drug therapy | Neurosciences | G proteins | Anxiety | Brain research | Genetic transcription | Neurons | Life Sciences | Human health and pathology | Other | Psychiatrics and mental health | medium spiny neurons | spatial learning | gene clustering | ethological scoring of anxiety | psychiatric disorders
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 08/2018, Volume 61, Issue 15, pp. 6748 - 6758
The orphan G-protein-coupled receptor GPR88 is highly expressed in the striatum. Studies using GPR88 knockout mice have suggested that the receptor is... 
CIRCUITRY | DESIGN | CHEMISTRY, MEDICINAL | BEHAVIOR | GENES | MOTOR | ANTAGONISTS | EXPRESSION | AGONISTS | DEPENDENCE
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/1997, Volume 272, Issue 44, pp. 27605 - 27611
Journal Article
Nature Neuroscience, ISSN 1097-6256, 2011, Volume 14, Issue 8, pp. 1017 - 1022
Zinc is abundant in the central nervous system and regulates pain, but the underlying mechanisms are unknown. In vitro studies have shown that extracellular... 
LOCALIZATION | DOMAIN | SYNAPTICALLY RELEASED ZINC | SPINAL-CORD | MICE | HYPERALGESIA | LONG-TERM POTENTIATION | ANTAGONISTS | NEUROSCIENCES | MOLECULAR-MECHANISMS | ZN2 | Xenopus | Pain Threshold - physiology | Membrane Potentials - genetics | Rotarod Performance Test - methods | Locomotion - genetics | Smell - genetics | Trace Elements - therapeutic use | Receptors, N-Methyl-D-Aspartate - metabolism | Reflex - drug effects | Trace Elements - pharmacology | Receptors, N-Methyl-D-Aspartate - genetics | Dose-Response Relationship, Drug | Smell - drug effects | DNA Mutational Analysis | Pain - drug therapy | Protein Binding - drug effects | Reaction Time - drug effects | Statistics, Nonparametric | Pain - etiology | Pain Threshold - drug effects | Spinal Cord - cytology | Neurons - drug effects | Disease Models, Animal | Locomotion - drug effects | Membrane Potentials - drug effects | Physical Stimulation | Touch Perception - genetics | Acoustic Stimulation | Mice, Inbred C57BL | Histidine - genetics | Serine - genetics | Mice, Transgenic | Reaction Time - genetics | Hippocampus - cytology | Mutation - genetics | Zinc - therapeutic use | Animals | Analysis of Variance | Larva | Pain - physiopathology | Mice | Zinc - pharmacology | In Vitro Techniques | Pain Measurement | Hand Strength - physiology | Touch Perception - drug effects | Neural receptors | Pain | Physiological aspects | Zinc in the body | Cellular signal transduction | Research | Membrane proteins
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2001, Volume 276, Issue 5, pp. 3130 - 3137
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 12/2010, Volume 30, Issue 49, pp. 16459 - 16468
delta-Opioid receptors are G-protein-coupled receptors that regulate nociceptive and emotional responses. It has been well established that distinct agonists... 
SPRAGUE-DAWLEY RATS | NEUROPATHIC PAIN | MICE DEFICIENT | MORPHINE | AGONIST SNC80 | CHRONIC INFLAMMATION | KNOCKOUT MICE | MEMBRANE TRAFFICKING | UP-REGULATION | NEUROSCIENCES | Analgesics - pharmacology | Calcium - metabolism | Drug Tolerance - genetics | Male | Ganglia, Spinal - cytology | Green Fluorescent Proteins - genetics | Drug Interactions | Piperidines - pharmacology | Time Factors | Protein Binding - drug effects | Brain - ultrastructure | Statistics, Nonparametric | Pain - etiology | Cell Membrane - drug effects | Disease Models, Animal | Locomotion - drug effects | Membrane Potentials - drug effects | Mice, Transgenic | Piperazines - therapeutic use | Piperazines - pharmacology | Protein Transport - genetics | Ligands | Mice | Receptors, Opioid, delta - agonists | Inflammation - chemically induced | Receptors, Opioid, delta - metabolism | Pain Threshold - physiology | Locomotion - genetics | Drug Tolerance - physiology | Protein Transport - physiology | Cell Membrane - genetics | Spinal Cord - ultrastructure | Patch-Clamp Techniques - methods | Inflammation - complications | Benzamides - therapeutic use | Pain - drug therapy | Receptors, Opioid, delta - genetics | Pain Threshold - drug effects | Female | Benzamides - pharmacology | Analgesics - therapeutic use | Mice, Inbred C57BL | Sulfur Isotopes - metabolism | Maze Learning - drug effects | Freund's Adjuvant | Hyperalgesia - physiopathology | Guanosine 5'-O-(3-Thiotriphosphate) - metabolism | Animals | Sensory Receptor Cells - drug effects | Hyperalgesia - drug therapy | Piperidines - therapeutic use
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2006, Volume 103, Issue 25, pp. 9691 - 9696
The combination of fluorescent genetically encoded proteins with mouse engineering provides a fascinating means to study dynamic biological processes in... 
Locomotion | Receptors | Endocytosis | Neuroscience | Neurons | Imaging | Fluorescence | Agonists |