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The EMBO Journal, ISSN 0261-4189, 02/2019, Volume 38, Issue 4, pp. e101526 - n/a
In the last decade, the generation and maintenance of organotypic structures has been propelled to the center stage of biomedical research. In the lung, a... 
STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Respiratory tract | Cell culture | Organoids | Lung | Lung diseases | Mimicry
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2019, Volume 9, Issue 1, pp. 6479 - 6479
Lung epithelial cell damage and dysfunctional repair play a role in the development of lung disease. Effective repair likely requires the normal functioning of... 
RENEWAL | REPAIR | AIRWAY | MULTIDISCIPLINARY SCIENCES | MOUSE | INJURY | EXPRESSION
Journal Article
by Lee, JH and Kim, CF
SCIENCE, ISSN 0036-8075, 11/2014, Volume 346, Issue 6211, pp. 810 - 811
  Lung development relies on temporal and spatial cues to pattern the structures that sustain life through oxygen exchange. Signals from mesenchymal cells that... 
MULTIDISCIPLINARY SCIENCES | MOUSE LUNG | Lungs | Cellular biology | Developmental biology | Stem cells | Exchange | Cues | Lining (process) | Cells (biology) | Differentiation | Mammals | Pools
Journal Article
Cell, ISSN 0092-8674, 05/2017, Volume 169, Issue 4, pp. 563 - 565
Tumors have long been suspected of hijacking stem cell mechanisms used for tissue maintenance and repair. Ge et al. now show that skin tumors exhibit merged... 
PROPAGATING CELLS | CARCINOMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Stem Cells | Cell Lineage | Chromatin | Wound Healing | Humans | Skin Neoplasms | Stem cells | Skin cancer | Respiratory tract diseases | Index Medicus
Journal Article
European respiratory review : an official journal of the European Respiratory Society, 06/2017, Volume 26, Issue 144
Journal Article
Cancer Research, ISSN 0008-5472, 05/2018, Volume 78, Issue 10 Supplement, pp. A22 - A22
Journal Article
Cancer Research, ISSN 0008-5472, 01/2016, Volume 76, Issue 2 Supplement, pp. A39 - A39
Journal Article
Science, ISSN 0036-8075, 11/2014, Volume 346, Issue 6211, pp. 810 - 811
Journal Article
Cancer Research, ISSN 0008-5472, 04/2011, Volume 71, Issue 8 Supplement, pp. SY12-01 - SY12-01
Journal Article
Cell, ISSN 0092-8674, 05/2017, Volume 169, Issue 4, pp. 563 - 565
Tumors have long been suspected of hijacking stem cell mechanisms used for tissue maintenance and repair. Ge et al. now show that skin tumors exhibit merged... 
Journal Article
Journal Article
GENES & DEVELOPMENT, ISSN 0890-9369, 12/2005, Volume 19, Issue 24, pp. 3043 - 3054
Genetic and cytologic data from Saccharomyces cerevisiae and mammals implicate the Mre11 complex, consisting of Mre11, Rad50, and Nbs1, as a sensor of DNA... 
ACTIVATION | PROTEIN | checkpoints | DNA damage signaling | apoptosis | DOUBLE-STRAND BREAKS | HISTONE H2AX | DEVELOPMENTAL BIOLOGY | S-PHASE CHECKPOINT | CELL BIOLOGY | TARGETED DISRUPTION | REPAIR | GENETICS & HEREDITY | IONIZING-RADIATION | ATAXIA-TELANGIECTASIA | CELLULAR-RESPONSE | Allelomorphism | Genetic research | Ataxia telangiectasia | Genetic aspects | Research | DNA damage
Journal Article
Nature, ISSN 0028-0836, 04/2015, Volume 520, Issue 7546, pp. 239 - 242
Non-small-cell lung cancer is the leading cause of cancer-related death worldwide(1). Chemotherapies such as the topoisomerase II (TopoII) inhibitor etoposide... 
SURVIVAL | ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | COMPLEXES | SWI/SNF | GENE-EXPRESSION PROFILES | MUTATIONS | DRUG-COMBINATION | POLYCOMB | MICROARRAY DATA | CANCER CELL-LINES | Polycomb Repressive Complex 2 - antagonists & inhibitors | Lung Neoplasms - drug therapy | Apoptosis - drug effects | Humans | Lung Neoplasms - pathology | Molecular Targeted Therapy | Antineoplastic Agents, Phytogenic - therapeutic use | Nuclear Proteins - genetics | DNA Helicases - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Lung Neoplasms - enzymology | Carcinoma, Non-Small-Cell Lung - genetics | Genes, erbB-1 - genetics | Etoposide - pharmacology | Etoposide - therapeutic use | Topoisomerase II Inhibitors - pharmacology | Transcription Factors - genetics | Anaphase - drug effects | Enhancer of Zeste Homolog 2 Protein | Topoisomerase II Inhibitors - therapeutic use | Xenograft Model Antitumor Assays | Animals | Cell Line, Tumor | Mice | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Antineoplastic Agents, Phytogenic - pharmacology | Cell Cycle - drug effects | Protein research | Care and treatment | Oncology, Experimental | Genetic aspects | Research | Lung cancer, Non-small cell | Drug therapy | Gene expression | Cancer | Proteins | Genes | Lung cancer | Genetic engineering | Mutation | Kinases | Cancer therapies | Deoxyribonucleic acid--DNA | Tumors | Apoptosis | Index Medicus | Etoposide | Chemotherapy | EZH2 inhibition | BRG1 | EGFR
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Proceedings of the National Academy of Sciences, ISSN 0027-8424, 04/2014, Volume 111, Issue 13, pp. 4745 - 4746
Journal Article
Cancer Cell, ISSN 1535-6108, 05/2014, Volume 25, Issue 5, pp. 590 - 604
Journal Article
Science (New York, N.Y.), 11/2014, Volume 346, Issue 6211, pp. 810 - 811
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2008, Volume 105, Issue 33, pp. 11857 - 11862
Understanding the pathways that control epithelial carcinogenesis is vital to the development of effective treatments. The Polycomb group family member Bmi1 is... 
Pulmonary alveoli | Cell growth | Messenger RNA | Lungs | Stem cells | Mice | Lesions | Progenitor cells | Tumors | Lung neoplasms | Non-small-cell lung cancer | Ink4a | Arf | p16 | TRANSFORMATION | P19(ARF) | MULTIDISCIPLINARY SCIENCES | SELF-RENEWAL | PROLIFERATION | IDENTIFICATION | CANCER | K-RAS | INK4A LOCUS | AIRWAY STEM | MYC TRANSGENIC MICE | non-small-cell lung cancer | Cell Proliferation | Proto-Oncogene Proteins p21(ras) - genetics | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Stem Cells - cytology | Stem Cells - metabolism | Cell Transformation, Neoplastic - genetics | Nuclear Proteins - deficiency | Proto-Oncogene Proteins p21(ras) - deficiency | Pulmonary Alveoli - metabolism | Pulmonary Alveoli - cytology | Bronchi - metabolism | Nuclear Proteins - genetics | Bronchi - cytology | Repressor Proteins - metabolism | Proto-Oncogene Proteins p21(ras) - metabolism | Lung Neoplasms - genetics | Proto-Oncogene Proteins - metabolism | Cells, Cultured | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Proto-Oncogene Proteins - deficiency | Cell Transformation, Neoplastic - metabolism | Mice, Knockout | Animals | Polycomb Repressive Complex 1 | Cell Transformation, Neoplastic - pathology | Cell proliferation | Lung cancer | Genetic aspects | Research | Carcinogenesis | Health aspects | Oncogenes | Medical treatment | Rodents | Index Medicus | Biological Sciences
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