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Circulation, ISSN 0009-7322, 11/2015, Volume 132, Issue Suppl_3 Suppl 3, pp. A17671 - A17671
BackgroundRecently, the TCF21 gene was linked to the highly replicated coronary artery disease (CAD) associated polymorphism in the 6q23 locus. TCF21 is... 
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 10/2019, Volume 9, Issue 1, pp. 1 - 7
High-sensitivity Troponin (hs-Tn) has emerged as a useful marker for patients with myocardial injury or heart failure. However, few studies have compared... 
MORTALITY | IMPACT | ASSAY | PERFORMANCE | MULTIDISCIPLINARY SCIENCES | MYOCARDIAL INJURY | OUTCOMES | ACUTE CORONARY SYNDROME | ASSOCIATION | CARDIOVASCULAR RISK | Brain natriuretic peptide | Phenotypes | Echocardiography | Stenosis | Troponin | Troponin I | Calcium-binding protein | Electrocardiography | Aorta | Blood pressure | Ventricle | Aortic valve | Heart diseases
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 11/2016, Volume 134, Issue Suppl_1 Suppl 1, pp. A18374 - A18374
BackgroundRecently, the TCF21 gene was linked to the highly replicated coronary artery disease (CAD) associated polymorphism in the 6q23 locus. We previously... 
Journal Article
Nature Communications, ISSN 2041-1723, 07/2016, Volume 7, Issue 1, p. 12092
Coronary artery disease (CAD) is the leading cause of mortality and morbidity, driven by both genetic and environmental risk factors. Meta-analyses of... 
MUSCLE-CELL DIFFERENTIATION | SMOOTH-MUSCLE | METAANALYSIS | OPEN CHROMATIN | MULTIDISCIPLINARY SCIENCES | SYSTEMS GENETICS | SUSCEPTIBILITY LOCI | RISK | WIDE ASSOCIATION | EXPRESSION | REVEALS | Chromatin - metabolism | Coronary Vessels - pathology | Genetic Predisposition to Disease | Genome-Wide Association Study | Basic Helix-Loop-Helix Transcription Factors - genetics | Transcription Factor AP-1 - genetics | Coronary Artery Disease - metabolism | Humans | Gene Expression Regulation | Myocytes, Smooth Muscle - pathology | Gene Expression Profiling | Transcription Factor AP-1 - metabolism | Coronary Vessels - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Base Sequence | Alleles | Coronary Artery Disease - genetics | Coronary Artery Disease - pathology | Primary Cell Culture | Genome, Human | Genomics - methods | Quantitative Trait Loci | Myocytes, Smooth Muscle - metabolism | Chromatin - chemistry | Myocardial infarction | Profiling | Smooth muscle | Cardiovascular disease | Smad3 protein | Genomes | Risk factors | Ecological risk assessment | Interleukin 6 | Interleukin 6 receptors | Genetic analysis | Heart diseases | Transforming growth factor-b1 | Bone morphogenetic protein 1 | Coronary artery | Muscles | Risk analysis | Coronary artery disease | Environmental risk | Loci | Morbidity | Quantitative trait loci | Coronary vessels | Regulatory mechanisms (biology) | Infarction | Gene mapping | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A13132 - A13132
BackgroundSmooth muscle cell (SMC) phenotypic modulation, a process by which quiescent SMCs in the arterial wall de-differentiate, proliferate and migrate into... 
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2015, Volume 66, Issue 15, pp. B263 - B264
  Patients were divided into improvement and deterioration groups according to change in LV ejection fraction (EF) before and 1 month after TAVR. 
Cardiovascular | Internal Medicine | Heart valve diseases | Electrocardiography | Heart attacks | Cardiology | Mortality
Journal Article
PLoS Genetics, ISSN 1553-7390, 05/2015, Volume 11, Issue 5
  To functionally link coronary artery disease (CAD) causal genes identified by genome wide association studies (GWAS), and to investigate the cellular and... 
Hypotheses | Transcription factors | Genes | Rodents | Atherosclerosis | Cardiovascular disease | Smooth muscle | Genomes | Binding sites
Journal Article
PLoS Genetics, ISSN 1553-7390, 05/2015, Volume 11, Issue 5
  Recent genome wide association studies have identified a number of genes that contribute to the risk for coronary heart disease. One such gene, TCF21,... 
Studies | Heart | Reporters | Transcription factors | Councils | Cardiovascular disease | Smooth muscle | Genomes | Gene expression
Journal Article
The International Journal of Cardiovascular Imaging, ISSN 1569-5794, 11/2017, Volume 33, Issue 11, pp. 1693 - 1701
Valvulo-arterial impedance (Zva) has been shown to predict worse outcome in medically managed aortic stenosis (AS) patients. We aimed to investigate the... 
Strain imaging | Medicine & Public Health | Ventricular impedance | Cardiology | Imaging / Radiology | Cardiac Imaging | Transcatheter aortic valve replacement | LOW-GRADIENT | CARDIAC & CARDIOVASCULAR SYSTEMS | VALVULOARTERIAL IMPEDANCE | VALVULAR HEART-DISEASE | PRESERVED EJECTION FRACTION | LOW-FLOW | HIGH-RISK PATIENTS | STENOSIS EAE/ASE RECOMMENDATIONS | LEFT-VENTRICULAR AFTERLOAD | 2-DIMENSIONAL SPECKLE-TRACKING | CLINICAL-PRACTICE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Multivariate Analysis | Prospective Studies | Ventricular Function, Left | Humans | Stress, Mechanical | Male | Aortic Valve - surgery | Echocardiography, Doppler, Color | Recovery of Function | Aortic Valve Stenosis - diagnostic imaging | Aortic Valve Stenosis - mortality | Arterial Pressure | Time Factors | Aged, 80 and over | Female | Aortic Valve Stenosis - surgery | Aorta - physiopathology | Transcatheter Aortic Valve Replacement - adverse effects | Severity of Illness Index | Aorta - diagnostic imaging | Aortic Valve - diagnostic imaging | Risk Factors | Aortic Valve Stenosis - physiopathology | Kaplan-Meier Estimate | Aortic Valve - physiopathology | Logistic Models | Treatment Outcome | Chi-Square Distribution | Regional Blood Flow | Stroke Volume | Biomechanical Phenomena | Aged | Transcatheter Aortic Valve Replacement - mortality | Health maintenance organizations | Medical research | Medical colleges | Mortality | Aortic valve stenosis | Medicine, Experimental | Rankings | Cardiovascular agents | Heart | Stroke | Recovery of function | Stenosis | Patients | Stroke volume | Electrocardiography | Aorta | Cutoffs | Blood pressure | Ventricle | Impedance | Heart diseases | Aortic valve
Journal Article
JACC: Heart Failure, ISSN 2213-1779, 12/2017, Volume 5, Issue 12, pp. 930 - 939
This study investigated to define graft dysfunction and to determine its incremental association with long-term outcome after heart transplantation (HT).... 
diastolic dysfunction | heart transplantation | right heart catheterization | rejection
Journal Article