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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2017, Volume 114, Issue 11, pp. E2243 - E2252
Rapid and efficient protocols to generate oligodendrocytes (OL) from human induced pluripotent stem cells (iPSC) are currently lacking, but may be a key... 
Myelination | Disease modeling | Forward patterning | Human iPSC | Oligodendrocytes | PROGENITOR CELLS | MUTANT TAU-PROTEIN | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | disease modeling | FRONTOTEMPORAL DEMENTIA | human iPSC | oligodendrocytes | PROCESS OUTGROWTH | PROGRESSIVE MULTIPLE-SCLEROSIS | MESSENGER-RNA | IN-VIVO | myelination | MOUSE SPINAL-CORD | DEVELOPMENTAL-CHANGES | forward patterning | Oligodendroglia - metabolism | Spinal Cord - metabolism | Oxidative Stress | Demyelinating Diseases - genetics | Humans | Transcriptome | tau Proteins - metabolism | Gene Expression Profiling | Demyelinating Diseases - metabolism | Neural Stem Cells - cytology | Spinal Cord - ultrastructure | Myelin Sheath - metabolism | Brain - metabolism | Myelin Basic Protein - genetics | Cell Differentiation - genetics | tau Proteins - genetics | Cell Death - genetics | Spinal Cord - pathology | Brain - ultrastructure | Oligodendroglia - cytology | Demyelinating Diseases - pathology | Induced Pluripotent Stem Cells - cytology | Cell Lineage - genetics | Disease Models, Animal | Induced Pluripotent Stem Cells - metabolism | Myelin Basic Protein - metabolism | Cells, Cultured | Ectopic Gene Expression | Transcription Factors - genetics | Transcription Factors - metabolism | Animals | Myelin Sheath - genetics | Biomarkers | Brain - pathology | Mice | Mutation | Neural Stem Cells - metabolism | Cluster Analysis | Cell proliferation | Physiological aspects | Dendritic cells | Observations | Stem cells | Biological Sciences | PNAS Plus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2014, Volume 289, Issue 47, pp. 32512 - 32525
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2016, Volume 291, Issue 27, pp. 14199 - 14212
The viral vector-mediated overexpression of the defined transcription factors, Brn4/Pou3f4, Sox2, Klf4, and c-Myc (BSKM), could induce the direct conversion of... 
regenerative medicine | BIOCHEMISTRY & MOLECULAR BIOLOGY | DIRECT CONVERSION | CNS | CARDIOMYOCYTES | INDUCTION | MODEL | neural stem cell (NSC) | reprogramming | cell biology | cell therapy | NEURONS | GENE-THERAPY | Animals | Transfection | Fibroblasts - cytology | Mice | Genetic Vectors | Neural Stem Cells - cytology | Mice, Inbred C3H | Index Medicus | Cell Biology
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2017, Volume 114, Issue 11, p. E2243
  Rapid and efficient protocols to generate oligodendrocytes (OL) from human induced pluripotent stem cells (iPSC) are currently lacking, but may be a key... 
Rodents | Medical treatment | Stem cells | Gene expression
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 03/2017, Volume 114, Issue 11, pp. E2243 - E2243
Rapid and efficient protocols to generate oligodendrocytes (OL) from human induced pluripotent stem cells (iPSC) are currently lacking, but may be a key... 
Journal Article
ISSN 2213-6711, 2018
Disorders of the biliary epithelium, known as cholangiopathies, cause severe and irreversible liver diseases. The limited accessibility of bile duct precludes... 
cholangiocyte progenitor cells | direct conversion | hepatic stem cells | Notch signal
Journal Article
Cell Reports, ISSN 2211-1247, 04/2016, Volume 15, Issue 4, pp. 814 - 829
Recent studies have shown that defined factors could lead to the direct conversion of fibroblasts into induced hepatocyte-like cells (iHeps). However, reported... 
direct conversion | conversion kinetics | MET | induced hepatocytes | Conversion kinetics | Induced hepatocytes | Direct conversion
Journal Article
Cell, ISSN 0092-8674, 08/2014, Volume 158, Issue 4, pp. 699 - 701
The manufacturing of clinically relevant cells is a widely used strategy in regenerative medicine. Cahan et al. develop a network biology platform named... 
DEFINED FACTORS | STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | FIBROBLASTS | MOUSE | CELL BIOLOGY | Systems Biology - methods | Stem Cells - cytology | Animals | Cell Engineering - methods | Humans | Developmental biology
Journal Article
EMBO reports, ISSN 1469-221X, 02/2017, Volume 18, Issue 2, pp. 319 - 333
Journal Article
Journal Article