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Autophagy, ISSN 1554-8627, 09/2014, Volume 10, Issue 9, pp. 1683 - 1684
Journal Article
Genes and Development, ISSN 0890-9369, 10/2011, Volume 25, Issue 19, pp. 1999 - 2010
Journal Article
Trends in Cell Biology, ISSN 0962-8924, 11/2017, Volume 27, Issue 11, p. 863
Tumors are dynamic pseudoorgans that contain numerous cell types interacting to create a unique physiology. Within this network, the malignant cells encounter... 
Signaling | Metabolites | Nutrients | Physiology | Metabolism | Drug development | Cancer therapies | Cells | Tumors | Cancer
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2015, Volume 21, Issue 8, pp. 1828 - 1834
Journal Article
Cell Metabolism, ISSN 1550-4131, 05/2017, Volume 25, Issue 5, pp. 1037 - 1043
Autophagy is a critical cellular process that generally protects cells and organisms from stressors such as nutrient deprivation. In addition to its role in... 
HYDROXYCHLOROQUINE | INHIBITION | INFLAMMATION | TARGETING AUTOPHAGY | GROWTH | ENDOCRINOLOGY & METABOLISM | SUPPRESSION | CANCER | TUMORIGENESIS | FIBROBLASTS | PROGRESSION | CELL BIOLOGY | Neoplasms - metabolism | Animals | Cell Proliferation | Metabolic Networks and Pathways | Cell Survival | Humans | Tumor Microenvironment | Neoplasms - pathology | Autophagy | Physiological aspects | Medical colleges | Cancer
Journal Article
CANCER DISCOVERY, ISSN 2159-8274, 09/2019, Volume 9, Issue 9, pp. 1167 - 1181
Autophagy, a multistep lysosomal degradation pathway that supports nutrient recycling and metabolic adaptation, has been implicated as a process that regulates... 
HYDROXYCHLOROQUINE | ADVANCED SOLID TUMORS | SIGNALING ADAPTER | PROTEIN | MTOR INHIBITION | ONCOLOGY | PHASE-I TRIAL | GROWTH | REQUIRE AUTOPHAGY | CELL-SURVIVAL | SELECTIVE AUTOPHAGY
Journal Article
Trends in Cell Biology, ISSN 0962-8924, 11/2017, Volume 27, Issue 11, pp. 863 - 875
Journal Article
Oncotarget, ISSN 1949-2553, 2011, Volume 2, Issue 12, pp. 1302 - 1306
Autophagy inhibition is a novel cancer therapeutic strategy in the early stages of clinical trial testing. The initial rationale for using autophagy inhibition... 
Therapy | Tumor | Metabolism | Ras | Autophagy | Cancer | Chloroquine - pharmacology | Animals | Signal Transduction - drug effects | Humans | Hydroxychloroquine - pharmacology | Neoplasms - radiotherapy | Antineoplastic Agents - pharmacology | Antineoplastic Agents - therapeutic use | Mice | Genes, ras | Autophagy - drug effects | Neoplasms - drug therapy
Journal Article
HAEMATOLOGICA, ISSN 0390-6078, 06/2019, Volume 104, Issue 7, pp. 1342 - 1354
Ncoa4 mediates autophagic degradation of ferritin, the cytosolic iron storage complex, to maintain intracellular iron homeostasis. Recent evidence also... 
POLYCYTHEMIA | HOMEOSTASIS | MACROPHAGES | PROTEIN EXPRESSION | ADAPTATION | MICE | IRON-DEFICIENCY | FERRITIN | HEMATOLOGY | BETA
Journal Article
Genes & Development, ISSN 0890-9369, 10/2011, Volume 25, Issue 19, pp. 1999 - 2010
Macroautophagy (referred to hereafter as autophagy) is a highly regulated cellular process that serves to remove damaged proteins and organelles from the cell.... 
Journal Article
Nature, ISSN 0028-0836, 04/2013, Volume 496, Issue 7443, pp. 101 - 105
Cancer cells have metabolic dependencies that distinguish them from their normal counterparts(1). Among these dependencies is an increased use of the amino... 
GLUCOSE | MULTIDISCIPLINARY SCIENCES | MASS-SPECTROMETRY | ADDICTION | TRANSFORMED-CELLS | Care and treatment | Pancreatic cancer | Physiological aspects | Development and progression | Research | Health aspects | Guanosine triphosphatase | Glutamine | Cancer | Enzymes | Oxidative stress | Glucose | Metabolites | Cancer therapies
Journal Article