X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
chemistry (69) 69
metallurgy (69) 69
biochemistry (60) 60
beer (59) 59
compositions thereof (59) 59
culture media (59) 59
enzymology (59) 59
microbiology (59) 59
microorganisms or enzymes (59) 59
mutation or genetic engineering (59) 59
propagating, preserving or maintaining microorganisms (59) 59
spirits (59) 59
vinegar (59) 59
wine (59) 59
organic chemistry (42) 42
human necessities (39) 39
hygiene (39) 39
medical or veterinary science (39) 39
preparations for medical, dental, or toilet purposes (39) 39
nucleosides (36) 36
derivatives thereof (35) 35
nucleic acids (35) 35
nucleotides (35) 35
sugars (35) 35
index medicus (22) 22
animals (16) 16
mice (15) 15
biochemistry & molecular biology (11) 11
chemistry, medicinal (9) 9
chemistry, organic (8) 8
humans (8) 8
male (8) 8
oligonucleotides, antisense - chemistry (8) 8
structure-activity relationship (8) 8
enzymes (7) 7
hepatocytes (7) 7
mice, inbred balb c (7) 7
rna (7) 7
specific therapeutic activity of chemical compounds ormedicinal preparations (7) 7
hepatocytes - metabolism (6) 6
liver - metabolism (6) 6
oligonucleotides, antisense - pharmacology (6) 6
peptides (6) 6
targeted delivery (6) 6
acetylgalactosamine - chemistry (5) 5
collagen (5) 5
expression (5) 5
mammalian-cells (5) 5
mice, inbred c57bl (5) 5
oligonucleotides, antisense - chemical synthesis (5) 5
acetylgalactosamine - pharmacology (4) 4
antisense oligonucleotides (4) 4
asialoglycoprotein receptor - metabolism (4) 4
base sequence (4) 4
binding sites (4) 4
cell line (4) 4
cells, cultured (4) 4
chemical properties (4) 4
chemistry, multidisciplinary (4) 4
circular-dichroism (4) 4
delivery (4) 4
duplexes (4) 4
hela cells (4) 4
hepatocytes - drug effects (4) 4
liver (4) 4
mechanisms (4) 4
molecular structure (4) 4
oligodeoxynucleotides (4) 4
rna interference (4) 4
rna, small interfering - metabolism (4) 4
acetylgalactosamine - analogs & derivatives (3) 3
argonaute proteins - genetics (3) 3
asialoglycoprotein receptor (3) 3
binding (3) 3
chemical biology and nucleic acid chemistry (3) 3
circular dichroism (3) 3
collagen - chemistry (3) 3
dendrimers (3) 3
dose-response relationship, drug (3) 3
galnac (3) 3
high-affinity (3) 3
mice, transgenic (3) 3
oligonucleotides, antisense - metabolism (3) 3
oligopeptides - chemistry (3) 3
peptide nucleic acids - administration & dosage (3) 3
peptide nucleic acids - chemistry (3) 3
peptide nucleic acids - pharmacokinetics (3) 3
phosphorothioate oligonucleotides - chemistry (3) 3
phosphorothioate oligonucleotides - metabolism (3) 3
pna (3) 3
protein binding (3) 3
rna, messenger - genetics (3) 3
rna, messenger - metabolism (3) 3
rna, small interfering - genetics (3) 3
scavenger receptors, class b - metabolism (3) 3
structure (3) 3
therapeutics (3) 3
acetylgalactosamine - chemical synthesis (2) 2
amino acid sequence (2) 2
analysis (2) 2
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Hepatology, ISSN 0168-8278, 04/2019, Volume 70, Issue 1, pp. e160 - e161
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 03/2017, Volume 45, Issue 5, pp. 2294 - 2306
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 7/2016, Volume 138, Issue 28, pp. 8694 - 8697
Incorporation of chemical modifications into small interfering RNAs (siRNAs) increases metabolic stability and improves tissue distribution. However, how these... 
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 07/2016, Volume 138, Issue 28, pp. 8694 - 8697
Journal Article
Molecules, ISSN 1420-3049, 2019, Volume 24, Issue 2, p. 225
We recently reported that (E)-5-vinylphosphonate (5-VP) is a metabolically-stable phosphate mimic for siRNA and demonstrated that 5-VP improves the potency of... 
Vinylphosphonate | SATE | SiRNA | vinylphosphonate | RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ARGONAUTE | siRNA | INTERFERENCE | DUPLEXES | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | Index Medicus
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 2015, Volume 43, Issue 6, pp. 2993 - 3011
The ss-siRNA activity in vivo requires a metabolically stable 5 '-phosphate analog. In this report we used crystal structure of the 5 '-phosphate binding... 
RNA INTERFERENCE | TARGET | ANIMALS | PHOSPHONATE ANALOGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESTERS | CLEAVAGE | ANTISENSE OLIGONUCLEOTIDES | CHEMICAL-MODIFICATIONS | MAMMALIAN-CELLS | NUCLEIC-ACIDS | Index Medicus
Journal Article
Journal Article
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 06/2017, Volume 45, Issue 11, p. 6994
Journal Article
Journal Article
Journal Article
Inorganic chemistry, ISSN 0020-1669, 02/2006, Volume 45, Issue 3, pp. 961 - 963
The synthesis and characterization of hydroxamic acid containing single-chain and TRIS-assembled (where TRIS is tris(carboxyethoxymethyl)aminomethane) collagen... 
Temperature | Iron - chemistry | Collagen - chemical synthesis | Hydroxamic Acids - chemistry | Collagen - chemistry | Molecular Structure | Structure-Activity Relationship | Binding Sites | Methylamines - chemistry | Iron compounds | Chemical properties | Collagen | Methyl groups | Index Medicus
Journal Article
NUCLEIC ACIDS RESEARCH, ISSN 0305-1048, 07/2019, Volume 47, Issue 12, pp. 6045 - 6058
We determined the effect of attaching palmitate, tocopherol or cholesterol to PS ASOs and their effects on plasma protein binding and on enhancing ASO potency... 
CELL UPTAKE | RNA | TRANSCYTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TISSUE | MOUSE | TRAFFICKING | MECHANISMS | TARGETED DELIVERY
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.