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Nature, ISSN 0028-0836, 2013, Volume 497, Issue 7447, pp. 108 - 112
Cancers acquire resistance to systemic treatment as a result of clonal evolution and selection(1,2). Repeat biopsies to study genomic evolution as a result of... 
HETEROGENEITY | LUNG-CANCER | ACTIVATION | EVOLUTION | VARIANTS | AXL | MULTIDISCIPLINARY SCIENCES | TAMOXIFEN RESISTANCE | TUMOR-CELLS | MUTATIONS | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Genomics | Humans | Ovarian Neoplasms - pathology | Lung Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Ovarian Neoplasms - genetics | Neoplasms - genetics | DNA Mutational Analysis | Female | Antineoplastic Agents - pharmacology | DNA, Neoplasm - analysis | Ovarian Neoplasms - drug therapy | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Intercellular Signaling Peptides and Proteins - genetics | Breast Neoplasms - drug therapy | Genome, Human - genetics | Neoplasms - drug therapy | Phosphatidylinositol 3-Kinases - genetics | Drug Resistance, Neoplasm - genetics | Exome - genetics | Breast Neoplasms - genetics | Class I Phosphatidylinositol 3-Kinases | Breast Neoplasms - pathology | Retinoblastoma Protein - genetics | Plasma - chemistry | Alleles | Carcinoma, Non-Small-Cell Lung - drug therapy | DNA, Neoplasm - genetics | Neoplasms - pathology | Mediator Complex Subunit 1 - genetics | Drug Resistance, Neoplasm - drug effects | Evolution, Molecular | Antimitotic agents | Care and treatment | Physiological aspects | Dosage and administration | Genetic aspects | Research | Nucleotide sequencing | Drug resistance | Antineoplastic agents | DNA sequencing | Blood plasma | Cancer | Plasma | Biopsy | Breast cancer | Genomes | Mutation | Patients | Deoxyribonucleic acid--DNA | Tumors | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 11/2015, Volume 6, Issue 1, pp. 8760 - 8760
Circulating tumour DNA analysis can be used to track tumour burden and analyse cancer genomes non-invasively but the extent to which it represents metastatic... 
HETEROGENEITY | ACTIVATION | VARIANTS | PATHWAY | MULTIDISCIPLINARY SCIENCES | KINASE | ACQUIRED-RESISTANCE | SEQUENCING DATA | Carcinoma, Ductal, Breast - genetics | Receptors, Estrogen - metabolism | Humans | Receptor, ErbB-2 - metabolism | Clonal Evolution - genetics | Tamoxifen - administration & dosage | Case-Control Studies | Breast Neoplasms - metabolism | Brain Neoplasms - secondary | Carcinoma, Ductal, Breast - drug therapy | Neoplasm Metastasis | Lung Neoplasms - secondary | Adult | Carcinoma, Ductal, Breast - pathology | Female | Quinazolines - administration & dosage | Liver Neoplasms - secondary | Carcinoma, Ductal, Breast - metabolism | Lung Neoplasms - genetics | Liver Neoplasms - genetics | Deoxycytidine - administration & dosage | Brain Neoplasms - genetics | Trastuzumab - administration & dosage | Breast Neoplasms - drug therapy | Sequence Analysis, DNA | Spinal Neoplasms - secondary | Breast Neoplasms - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Spinal Neoplasms - genetics | Bayes Theorem | DNA, Neoplasm - genetics | Mutation | Deoxycytidine - analogs & derivatives | Biological evolution | Breast cancer | Genomes | Metastasis | ErbB-2 protein | Patients | Metastases | Heterogeneity | Biopsy | Breast | Evolution | Deoxyribonucleic acid--DNA | Cancer | Tumors | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 01/2010, Volume 463, Issue 7278, pp. 191 - 196
Journal Article
by Loch, Jennifer A and Li, Heng and Walter, Klaudia and Liao, Arnold K and Chris Pinkard, D and Ivanov, Denis V and O'Neill, Michael J and Aniebo, Ify C and Haudenschild, Christian D and Ewan, Mark R and Earnshaw, David J and Ernest Sohna Sohna, Jean and Spence, Eric J and Worsley, Graham J and Goddard, Colin P and Bailey, David M. D and Ling Ng, Bee and Moon, Keith W and Carter, Richard J and Khrebtukova, Irina and Mullikin, James C and Parkinson, Michael L and Banerjee, Saibal and Harnish, Kevin and Sizto, Ning L and Etchin, Sergey S and Smith, Mark E and Shaw, Richard J and Novo, Sonia M and Ning, Zemin and Diakoumakos, Konstantinos D and Alam, Mohammed D and Bridgham, John A and Sluis, Johannes P and Mammen, Radhika M and Lok, Mitch and Egbujor, Ugonna C and Pickering, Lea and Scott Furey, W and Kumar, Anil and Mehta, Parul and Barbour, Selena G and Brown, Clive G and Rae, Vicki H and Luo, Shujun and Zuerlein, Mike and Torrance, Peta E and Hoschler, Katya and Rogers, Jane and Smith, Vincent P and Elmore, David W and Ostadan, Omead and Sabot, Andrea and Neil Cooley, R and Evers, Dirk J and Fedurco, Milan and Heyer, Narinder I and Karbelashvili, Mirian S and Black, Phillip J and Brown, Andrew A and Romieu, Anthony and Rawlings, Stephen R and Cox, Anthony J and Bignell, Helen R and Castillo, Nestor and Virk, Selene M and McCooke, Nick J and Durbin, Richard and Ellis, Darren J and Pliskin, Daniel P and Ruediger, Silke T and Boutell, Jonathan M and vandeVondele, Stephanie and Schenker, Martin R and Rasolonjatovo, Isabelle M. J and Hims, Matthew M and Benson, Kevin F and Yan, Juying and Seoane, Josefina M and Walcott, Gregory C and Irving, Leslie J and Rogers, John and Granieri, Philip A and Hurwitz, Steve and Milton, John and Smith, Geoffrey P and Rogert Bacigalupo, Maria C and McCauley, Patrick G and Sutton, Neil and Obradovic, Bojan and Tzonev, Svilen S and Stevens, Kim and Buermann, Dale H and Quijano, Victor J and Anastasi, Carole and Rigatti, Roberto and Benoit, Vincent A and Crake, Natasha R and Bundu, Abass A and Scally, Aylwyn and ...
Nature, ISSN 0028-0836, 11/2008, Volume 456, Issue 7218, pp. 53 - 59
Journal Article
by Taylor, Jenny C and Martin, Hilary C and Lise, Stefano and Broxholme, John and Cazier, Jean-Baptiste and Rimmer, Andy and Kanapin, Alexander and Lunter, Gerton and Fiddy, Simon and Allan, Chris and Aricescu, A. Radu and Attar, Moustafa and Babbs, Christian and Becq, Jennifer and Beeson, David and Bento, Celeste and Bignell, Patricia and Blair, Edward and Buckle, Veronica J and Bull, Katherine and Cais, Ondrej and Cario, Holger and Chapel, Helen and Copley, Richard R and Cornall, Richard and Craft, Jude and Dahan, Karin and Davenport, Emma E and Dendrou, Calliope and Devuyst, Olivier and Fenwick, Aimée L and Flint, Jonathan and Fugger, Lars and Gilbert, Rodney D and Goriely, Anne and Green, Angie and Greger, Ingo H and Grocock, Russell and Gruszczyk, Anja V and Hastings, Robert and Hatton, Edouard and Higgs, Doug and Hill, Adrian and Holmes, Chris and Howard, Malcolm and Hughes, Linda and Humburg, Peter and Johnson, David and Karpe, Fredrik and Kingsbury, Zoya and Kini, Usha and Knight, Julian C and Krohn, Jonathan and Lamble, Sarah and Langman, Craig and Lonie, Lorne and Luck, Joshua and McCarthy, Davis and McGowan, Simon J and McMullin, Mary Frances and Miller, Kerry A and Murray, Lisa and Németh, Andrea H and Nesbit, M. Andrew and Nutt, David and Ormondroyd, Elizabeth and Bang Oturai, Annette and Pagnamenta, Alistair and Patel, Smita Y and Percy, Melanie and Petousi, Nayia and Piazza, Paolo and Piret, Sian E and Polanco-Echeverry, Guadalupe and Popitsch, Niko and Powrie, Fiona and Pugh, Chris and Quek, Lynn and Robbins, Peter A and Robson, Kathryn and Russo, Alexandra and Sahgal, Natasha and Van Schouwenburg, Pauline A and Schuh, Anna and Silverman, Earl and Simmons, Alison and Sorensen, Per Soelberg and Sweeney, Elizabeth and Taylor, John and Thakker, Rajesh V and Tomlinson, Ian and Trebes, Amy and Twigg, Stephen R. F and Uhlig, Holm H and Vyas, Paresh and Vyse, Tim and Wall, Steven A and Watkins, Hugh and Whyte, Michael P and Witty, Lorna and ...
Nature Genetics, ISSN 1061-4036, 06/2015, Volume 47, Issue 7, pp. 717 - 726
Journal Article
by Ross-Innes, Caryn S and Becq, Jennifer and Warren, Andrew and Cheetham, R Keira and Northen, Helen and O'Donovan, Maria and Malhotra, Shalini and Di Pietro, Massimiliano and Ivakhno, Sergii and He, Miao and Weaver, Jamie M.J and Lynch, Andy G and Kingsbury, Zoya and Ross, Mark and Humphray, Sean and Bentley, David and Fitzgerald, Rebecca C and Hayes, Stephen J and Ang, Yeng and Welch, Ian and Preston, Shaun and Oakes, Sarah and Save, Vicki and Skipworth, Richard and Tucker, Olga and Davies, Jim and Crichton, Charles and Schusterreiter, Christian and Underwood, Tim and Noble, Fergus and Stacey, Bernard and Kelly, Jamie and Byrne, James and Haydon, Annette and Sharland, Donna and Owsley, Jack and Barr, Hugh and Lagergren, Jesper and Gossage, James and Davies, Andrew and Mason, Robert and Chang, Fuju and Zylstra, Janine and Sanders, Grant and Wheatley, Tim and Berrisford, Richard and Bracey, Tim and Harden, Catherine and Bunting, David and Roques, Tom and Nobes, Jenny and Loo, Suat and Lewis, Mike and Cheong, Ed and Priest, Oliver and Parsons, Simon L and Soomro, Irshad and Kaye, Philip and Saunders, John and Pang, Vincent and Welch, Neil and Catton, James A and Duffy, John P and Ragunath, Krish and Lovat, Laurence and Haidry, Rehan and Miah, Haroon and Kerr, Sarah and Eneh, Victor and Butawan, Rommel and Lewis, Michael and Cheong, Edward and Kumar, Bhasker and Igali, Laszlo and Walton, Sharon and Dann, Adela and Safranek, Peter and Hindmarsh, Andy and Sudjendran, Vijayendran and Scott, Michael and Cluroe, Alison and Miremadi, Ahmad and Mahler-Araujo, Betania and Nutzinger, Barbara and Peters, Chris and Abdullahi, Zarah and Crawte, Jason and MacRae, Shona and Noorani, Ayesha and Elliott, Rachael Fels and Bower, Lawrence and Edwards, Paul and Tavare, Simon and Eldridge, Matthew and Bornschein, Jan and Secrier, Maria and Yang, Tsun-Po and O'Neill, J. Robert and Adamczuk, Kasia and Lao-Sirieix, Pierre and ... and Oesophageal Canc Clinical & Mol St and for the Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Study Group
Nature Genetics, ISSN 1061-4036, 08/2015, Volume 47, Issue 9, pp. 1038 - 1046
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