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Annual Review of Microbiology, ISSN 0066-4227, 01/2015, Volume 69, p. 341
  Some hours after invading the erythrocytes of its human host, the malaria parasite Plasmodium falciparum induces an increase in the permeability of the... 
Proteins | Membranes | Malaria | Erythrocytes | Ions | Parasites | Permeability
Journal Article
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 06/2018, Volume 62, Issue 6
For an increasing number of antimalarial agents identified in high-throughput phenotypic screens, there is evidence that they target PfATP4, a putative Na+... 
Transporters | PfATP4 | Antimalarial agents | KAE609 | TARGET | INTRAERYTHROCYTIC MALARIA PARASITE | antimalarial agents | ACID | transporters | MEMBRANE-PERMEABILITY | MICROBIOLOGY | SPIROINDOLONE ANTIMALARIALS | PLASMODIUM-FALCIPARUM | PHARMACOLOGY & PHARMACY | RED-BLOOD-CELLS | ERYTHROCYTE | CATION ATPASE PFATP4 | EXTRUSION
Journal Article
Science, ISSN 0036-8075, 9/2009, Volume 325, Issue 5948, pp. 1680 - 1682
The emergence and spread of chloroquine-resistant Plasmodium falciparum malaria parasites has been a disaster for world health. Resistance is conferred by... 
Medical research | Reports | Cell membranes | Parasitism | Parasites | Inhibitory concentration 50 | Organelles | Genetic mutation | Oocytes | Vacuoles | EFFLUX | MECHANISM | PLASMODIUM-FALCIPARUM | MULTIDISCIPLINARY SCIENCES | AGENTS | PFCRT MUTATIONS | DIGESTIVE VACUOLE | Chloroquine - metabolism | Molecular Sequence Data | Plasmodium falciparum - drug effects | Protozoan Proteins - genetics | Chloroquine - analogs & derivatives | Chloroquine - pharmacology | Protozoan Proteins - metabolism | Membrane Transport Proteins - genetics | Plasmodium falciparum - genetics | Membrane Transport Proteins - metabolism | Plasmodium falciparum - metabolism | Protozoan Proteins - chemistry | Biological Transport - drug effects | Cell Membrane - metabolism | Drug Resistance | Recombinant Proteins - metabolism | Amino Acid Sequence | Antimalarials - metabolism | Oocytes - metabolism | Xenopus laevis | Recombinant Proteins - chemistry | Mutant Proteins - metabolism | Verapamil - pharmacology | Antimalarials - pharmacology | Membrane Transport Proteins - chemistry | Animals | Membrane Potentials | Mutant Proteins - chemistry | Mutation | Oligopeptides - pharmacology | Hydrogen-Ion Concentration | Plasmodium falciparum | Chloroquine | Biological transport, Active | Physiological aspects | Research | Properties | Membrane proteins | Proteins | Antibiotics | Malaria | Drug resistance | Molecular biology | Mutations | Integrals | Spreads | Transport | Transporter
Journal Article
Cellular Microbiology, ISSN 1462-5814, 06/2016, Volume 18, Issue 6, pp. 820 - 830
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 8795 - 15
Four hundred structurally diverse drug-like compounds comprising the Medicines for Malaria Venture's 'Pathogen Box' were screened for their effect on a range... 
TARGET | ACID | PLASMODIUM-FALCIPARUM | MULTIDISCIPLINARY SCIENCES | CANDIDATE | CATION ATPASE PFATP4 | EXTRUSION
Journal Article