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JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2017, Volume 69, Issue 16, pp. 2054 - 2063
Journal Article
Journal of Vascular Surgery, ISSN 0741-5214, 05/2017, Volume 65, Issue 5, p. 1550
Journal Article
Journal of Vascular Surgery, ISSN 0741-5214, 05/2017, Volume 65, Issue 5, pp. 1550 - 1550
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 12/2016, Volume 68, Issue 25, pp. 2761 - 2772
Journal Article
Nature Genetics, ISSN 1061-4036, 09/2017, Volume 49, Issue 9, pp. 1392 - 1397
UK Biobank is among the world's largest repositories for phenotypic and genotypic information in individuals of European ancestry1. We performed a genome-wide... 
PROVIDES INSIGHTS | METAANALYSIS | GENETICS & HEREDITY | NUCLEOTIDE EXCHANGE FACTOR | SUSCEPTIBILITY LOCI | ARCHITECTURE | RISK | TRAITS | VARIANT | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Leukocyte Rolling - genetics | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Middle Aged | Cells, Cultured | Genotype | Logistic Models | Male | United Kingdom | Rho Guanine Nucleotide Exchange Factors - genetics | Health Information Systems | Carrier Proteins - genetics | Phenotype | Coronary Artery Disease - genetics | Coronary Artery Disease - pathology | HEK293 Cells | Insulin Resistance - genetics | Adult | Female | Aged | Polymorphism, Single Nucleotide | Transendothelial and Transepithelial Migration - genetics | Complications and side effects | Development and progression | Insulin resistance | Genetic aspects | Disease susceptibility | Research | Coronary heart disease | Repositories | Leukocyte migration | Nucleotide sequence | Migration | Coronary artery | Genomes | Leukocytes | Insulin | Coronary artery disease | Disease control | Loci | Disease resistance | Pathways | Genetic analysis | DNA methylation | Gene loci | Mutation | Heart diseases | Deoxyribonucleic acid--DNA | coronary artery disease | population genetics | gene-expression | genome-wide association studies
Journal Article
by Liu, Dajiang J and Peloso, Gina M and Yu, Haojie and Butterworth, Adam S and Wang, Xiao and Mahajan, Anubha and Saleheen, Danish and Emdin, Connor and Alam, Dewan and Alves, Alexessander Couto and Amouyel, Philippe and Di Angelantonio, Emanuele and Arveiler, Dominique and Assimes, Themistocles L and Auer, Paul L and Baber, Usman and Ballantyne, Christie M and Bang, Lia E and Benn, Marianne and Bis, Joshua C and Boehnke, Michael and Boerwinkle, Eric and Bork-Jensen, Jette and Bottinger, Erwin P and Brandslund, Ivan and Brown, Morris and Busonero, Fabio and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Y. Eugene and Chen, Yii-Der Ida and Chowdhury, Rajiv and Christensen, Cramer and Chu, Auey Y and Connell, John M and Cucca, Francesco and Cupples, L. Aienne and Damrauer, Scott M and Davies, Gail and Deary, Ian J and Dedoussis, George and Denny, Joshua C and Dominiczak, Anna and Dubé, Marie-Pierre and Ebeling, Tapani and Eiriksdottir, Gudny and Esko, Tõnu and Farmaki, Aliki-Eleni and Feitosa, Mary F and Ferrario, Marco and Ferrieres, Jean and Ford, Ian and Fornage, Myriam and Franks, Paul W and Frayling, Timothy M and Frikke-Schmidt, Ruth and Fritsche, Lars G and Frossard, Philippe and Fuster, Valentin and Ganesh, Santhi K and Gao, Wei and Garcia, Melissa E and Gieger, Christian and Giulianini, Franco and Goodarzi, Mark O and Grallert, Harald and Grarup, Niels and Groop, Leif and Grove, Megan L and Gudnason, Vilmundur and Hansen, Torben and Harris, Tamara B and Hayward, Caroline and Hirschhorn, Joel N and Holmen, Oddgeir L and Huffman, Jennifer and Huo, Yong and Hveem, Kristian and Jabeen, Sehrish and Jackson, Anne U and Jakobsdottir, Johanna and Jarvelin, Marjo-Riitta and Jensen, Gorm B and Jørgensen, Marit E and Jukema, J. Wouter and Justesen, Johanne M and Kamstrup, Pia R and Kanoni, Stavroula and Karpe, Freik and Kee, Frank and Khera, Amit V and Klarin, Derek and Koistinen, Heikki A and Kooner, Jaspal S and Kooperberg, Charles and Kuulasmaa, Kari and Kuusisto, Johanna and Laakso, Markku and Lakka, Timo and ... and VA Million Veteran Program and Charge Diabet Working Grp and EPIC-CVD Consortium and EPIC-InterAct Consortium and GOLD Consortium and Charge Diabetes Working Group and The EPIC-InterAct Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Umeå universitet and Medicin
Nature genetics, ISSN 1061-4036, 2017, Volume 49, Issue 12, pp. 1758 - 1766
We screened variants on an exome-focused genotyping array in >300,000 participants (replication in >280,000 participants) and identified 444 independent... 
APOBEC-1 COMPLEMENTATION FACTOR | MYELOPROLIFERATIVE DISORDERS | LOW-FREQUENCY | CLONAL HEMATOPOIESIS | B MESSENGER-RNA | GENETICS & HEREDITY | TYROSINE KINASE JAK2 | CARDIOVASCULAR-DISEASE | MACULAR DEGENERATION | GENETIC ARCHITECTURE | CODING-SEQUENCE VARIANTS | Genetic Predisposition to Disease - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Risk Factors | Genetic Association Studies - methods | Genotype | Coronary Artery Disease - blood | Macular Degeneration - blood | Genetic Variation | Diabetes Mellitus, Type 2 - blood | Exome - genetics | Phenotype | Macular Degeneration - genetics | Lipids - blood | Coronary Artery Disease - genetics | Genome-wide association studies | Genetic aspects | Blood lipids | Identification and classification | Methods | Plasma | Lipoproteins (low density) | Liver | Lipids | Risk | Cardiovascular disease | Genomes | Macular degeneration | Consortia | Janus kinase 2 | Heart diseases | Lipoproteins (high density) | Age | Diabetes mellitus | Coronary artery | Health risks | Thalassemia | Triglycerides | Coronary artery disease | Loci | Cholesterol | Lipolysis | Studies | Lipoproteins | Genotyping | Alleles | Quality control | Diabetes | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Christophersen, Ingrid E and Rienstra, Michiel and Roselli, Carolina and Yin, Xiaoyan and Geelhoed, Bastiaan and Barnard, John and Lin, Honghuang and Arking, Dan E and Smith, Albert V and Albert, Christine M and Chaffin, Mark and Tucker, Nathan R and Li, Molong and Klarin, Derek and Bihlmeyer, Nathan A and Low, Siew-Kee and Weeke, Peter E and Mueller-Nurasyid, Martina and Smith, J. Gustav and Brody, Jennifer A and Niemeijer, Maartje N and Doerr, Marcus and Trompet, Stella and Huffman, Jennifer and Gustafsson, Stefan and Schurmann, Claudia and Kleber, Marcus E and Lyytikainen, Leo-Pekka and Seppala, Ilkka and Malik, Rainer and Horimoto, Anea R. V. R and Perez, Marco and Sinisalo, Juha and Aeschbacher, Stefanie and Theriault, Sebastien and Yao, Jie and Radmanesh, Farid and Weiss, Stefan and Teumer, Alexander and Choi, Seung Hoan and Weng, Lu-Chen and Clauss, Sebastian and Deo, Rajat and Rader, Daniel J and Shah, Svati H and Sun, Albert and Hopewell, Jemma C and Debette, Stephanie and Chauhan, Ganesh and Yang, Qiong and Worrall, Bradford B and Pare, Guillaume and Kamatani, Yoichiro and Hagemeijer, Yanick P and Verweij, Niek and Siland, Joylene E and Kubo, Michiaki and Smith, Jonathan D and Van Wagoner, David R and Bis, Joshua C and Perz, Siegfried and Psaty, Bruce M and Ridker, Paul M and Magnani, Jared W and Harris, Tamara B and Launer, Lenore J and Shoemaker, M. Benjamin and Padmanabhan, Sandosh and Haessler, Jeffrey and Bartz, Traci M and Waldenberger, Melanie and Lichtner, Peter and Arendt, Marina and Krieger, Jose E and Kahonen, Mika and Risch, Lorenz and Mansur, Alfredo J and Peters, Annette and Smith, Blair H and Lind, Lars and Scott, Stuart A and Lu, Yingchang and Bottinger, Erwin B and Hernesniemi, Jussi and Lindgren, Cecilia M and Wong, Jorge A and Huang, Jie and Eskola, Markku and Morris, Anew P and Ford, Ian and Reiner, Alex P and Delgado, Graciela and Chen, Lin Y and Chen, Yii-Der Ida and Sandhu, Roopinder K and Li, Man and Boerwinkle, Eric and Eisele, Lewin and Lannfelt, Lars and Rost, Natalia and ... and Neurology Working Grp CHARGE and AFGen Consortium and METASTROKE Consortium ISGC and METASTROKE Consortium of the ISGC and Neurology Working Group of the CHARGE Consortium and the AFGen Consortium and Science for Life Laboratory, SciLifeLab and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Geriatrik and Kardiovaskulär epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi and Institutionen för folkhälso- och vårdvetenskap
Nature Genetics, ISSN 1061-4036, 06/2017, Volume 49, Issue 6, pp. 946 - 952
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 11/2018, Volume 50, Issue 11, pp. 1514 - 1523
The Million Veteran Program (MVP) was established in 2011 as a national research initiative to determine how genetic variation influences the health of US... 
Cardiovascular Diseases - ethnology | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Hispanic Americans - statistics & numerical data | Male | Cardiovascular Diseases - genetics | Diabetes Mellitus, Type 2 - ethnology | Ethnic Groups - genetics | Lipids - blood | Cardiovascular Diseases - blood | Female | Lipid Metabolism - genetics | African Continental Ancestry Group - genetics | Ethnic Groups - statistics & numerical data | European Continental Ancestry Group - genetics | Genome-Wide Association Study | Hispanic Americans - genetics | European Continental Ancestry Group - statistics & numerical data | Genotype | African Continental Ancestry Group - statistics & numerical data | Diabetes Mellitus, Type 2 - blood | Aged | Polymorphism, Single Nucleotide | Veterans - statistics & numerical data | Wellness programs | Usage | Genetic variation | Analysis | Military personnel | Genetic aspects | Research | Blood lipids | Health aspects | Laboratories | Veterans | Angioplasty | Lipids | Cardiovascular disease | Genomes | Electronic medical records | Blood | Consortia | Aorta | Genetics | Diabetes mellitus (non-insulin dependent) | Heart diseases | Phenotypes | Research & development--R&D | Diabetes mellitus | Data processing | Principal components analysis | Triglycerides | Genetic diversity | Cholesterol | Abdomen | Meta-analysis | Studies | Quality control | Gene loci | Diabetes | Mutation | Electronic health records | Hispanics | coronary artery disease | population genetics | genome-wide association studies
Journal Article