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analysis (4) 4
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dna sequencing (2) 2
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novel domains (2) 2
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animals (1) 1
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bee venoms - genetics (1) 1
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1. Full Text Origins and structural properties of novel and de novo protein domains during insect evolution
by Klasberg, Steffen and Bitard‐Feildel, Tristan and Callebaut, Isabelle and Bornberg‐Bauer, Erich
The FEBS Journal, ISSN 1742-464X, 07/2018, Volume 285, Issue 14, pp. 2605 - 2625
Over long time scales, protein evolution is characterized by modular rearrangements of protein domains. Such rearrangements are mainly caused by gene... 
de novo domains | novel domains | domain evolution | protein disorder | PHYLOGENETIC ANALYSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | EMERGENCE | POSITIVE SELECTION | GENE | DATABASE | DYNAMICS | DISORDER | BIRTH | ADAPTIVE BENEFITS | Proteins | Noncoding DNA | Nucleotide sequencing | Analysis | Genomics | DNA sequencing | Cluster analysis | Origins | Nucleotide sequence | Biological evolution | Species comparisons | Migration | Homology | Genomes | Hydrophobicity | Gene fusion | Gene sequencing | Insects | Emergence | Gene duplication | Speciation | Deoxyribonucleic acid--DNA
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2. Full Text P084 Typing in the third generation: A HLA typing approach for nanopore sequencing data
by Klasberg, Steffen and Putke, Kathrin and Surendranath, Vineeth and Schmidt, Alexander and Lange, Vinzenz and Schöfl, Gerhard
Human Immunology, ISSN 0198-8859, 09/2019, Volume 80, pp. 116 - 116
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3. Full Text P061Allele-level genotyping of KIR2DL4 in large european population samples reveals highly significant heterozygote excess for 9A/10A allelic variants
by Schöfl, Gerhard and Sauter, Jürgen and Klasberg, Steffen and Schmidt, Alexander H and Lange, Vinzenz
Human Immunology, ISSN 0198-8859, 10/2018, Volume 79, pp. 106 - 106
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.humimm.2018.07.120 In... 
Killer cells | Genes
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4. Full Text Bioinformatics Strategies, Challenges, and Opportunities for Next Generation Sequencing-Based HLA Genotyping
by Klasberg, Steffen and Surendranath, Vineeth and Lange, Vinzenz and Schöfl, Gerhard
Transfusion Medicine and Hemotherapy, ISSN 1660-3796, 10/2019, Volume 46, Issue 5, pp. 312 - 325
The advent of next generation sequencing (NGS) has altered the face of genotyping the human leukocyte antigen (HLA) system in clinical, stem cell donor... 
Review Article | RNA | HIGH-THROUGHPUT | CELL TRANSPLANTATION | IMMUNOLOGY | Next generation sequencing | NANOPORE | HUMAN-LEUKOCYTE ANTIGEN | Genotyping | KIR | Human leukocyte antigen | DNA | HIGH-RESOLUTION | PCR AMPLIFICATION | HEMATOLOGY | CAPTURE
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5. Full Text Computational Identification of Novel Genes: Current and Future Perspectives
by Steffen Klasberg and Tristan Bitard-Feildel and Ludovic Mallet
Bioinformatics and Biology Insights, ISSN 1177-9322, 08/2016, Volume 2016, Issue 10, pp. 121 - 131
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6. Full Text P062Coding and non-coding variation in 60 novel full-length sequences of KIR2DL1
by Klasberg, Steffen and Lang, Kathrin and Günther, Marie and Schmidt, Alexander H and Lange, Vinzenz and Schöfl, Gerhard
Human Immunology, ISSN 0198-8859, 10/2018, Volume 79, pp. 106 - 106
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.humimm.2018.07.121... 
Proteins | Killer cells | Histocompatibility antigens | Analysis | HLA histocompatibility antigens | Genetic research | Nucleotides | Nucleotide sequencing | Protein binding | DNA sequencing
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7. Full Text The genomes of two key bumblebee species with primitive eusocial organization
by Sadd, Ben M and Barribeau, Seth M and Bloch, Guy and de Graaf, Dirk C and Dearden, Peter and Elsik, Christine G and Gadau, Jürgen and Grimmelikhuijzen, Cornelis J.P and Hasselmann, Martin and Lozier, Jeffrey D and Robertson, Hugh M and Smagghe, Guy and Stolle, Eckart and Van Vaerenbergh, Matthias and Waterhouse, Robert M and Bornberg-Bauer, Erich and Klasberg, Steffen and Bennett, Anna K and Câmara, Francisco and Guigó, Roderic and Hoff, Katharina and Mariotti, Marco and Munoz-Torres, Monica and Murphy, Terence and Santesmasses, Didac and Amdam, Gro V and Beckers, Matthew and Beye, Martin and Biewer, Matthias and Bitondi, Márcia M.G and Blaxter, Mark L and Bourke, Andrew F.G and Brown, Mark J.F and Buechel, Severine D and Cameron, Rossanah and Cappelle, Kaat and Carolan, James C and Christiaens, Olivier and Ciborowski, Kate L and Clarke, David F and Colgan, Thomas J and Collins, David H and Cridge, Andrew G and Dalmay, Tamas and Dreier, Stephanie and du Plessis, Louis and Duncan, Elizabeth and Erler, Silvio and Evans, Jay and Falcon, Tiago and Flores, Kevin and Freitas, Flávia C.P and Fuchikawa, Taro and Gempe, Tanja and Hartfelder, Klaus and Hauser, Frank and Helbing, Sophie and Humann, Fernanda C and Irvine, Frano and Jermiin, Lars S and Johnson, Claire E and Johnson, Reed M and Jones, Andrew K and Kadowaki, Tatsuhiko and Kidner, Jonathan H and Koch, Vasco and Köhler, Arian and Kraus, F. Bernhard and Lattorff, H. Michael G and Leask, Megan and Lockett, Gabrielle A and Mallon, Eamonn B and Antonio, David S. Marco and Marxer, Monika and Meeus, Ivan and Moritz, Robin F.A and Nair, Ajay and Näpflin, Kathrin and Nissen, Inga and Niu, Jinzhi and Nunes, Francis M.F and Oakeshott, John G and Osborne, Amy and Otte, Marianne and Pinheiro, Daniel G and Rossié, Nina and Rueppell, Olav and Santos, Carolina G and Schmid-Hempel, Regula and Schmitt, Björn D and Schulte, Christina and Simões, Zilá L.P and Soares, Michelle P.M and Swevers, Luc and Winnebeck, Eva C and Wolschin, Florian and Yu, Na and Zdobnov, Evgeny M and Aqrawi, Peshtewani K and Blankenburg, Kerstin P and ...
Genome Biology, ISSN 1474-7596, 04/2015, Volume 16, Issue 1, p. 76
Background: The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to... 
DNA METHYLATION | DROSOPHILA-MELANOGASTER | HIGH-THROUGHPUT | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | MALE COURTSHIP BEHAVIOR | GENETICS & HEREDITY | PHYLOGENETIC ANALYSES | BEE APIS-MELLIFERA | BOMBUS-TERRESTRIS LINNAEUS | HONEY-BEE | MULTIPLE SEQUENCE ALIGNMENT | SEX-DETERMINATION PATHWAY | Chemoreceptor Cells - metabolism | Selenoproteins - genetics | Species Specificity | Interspersed Repetitive Sequences | Genomics | Open Reading Frames | Synteny | Databases, Genetic | Bees - classification | Male | Behavior, Animal | Social Behavior | Female | Genes, Insect | Bee Venoms - genetics | Gene Expression Regulation | Chromosome Mapping | Sequence Analysis, DNA | Selenoproteins - metabolism | Bees - physiology | Animals | Gene Rearrangement | Bees - genetics | Polymorphism, Single Nucleotide | Evolution, Molecular | Eusociality | Gene regulation | Genes | Pollinators | MiRNA | Detoxification | Evolutionary genetics | Genomes | Chemoreception | Bees | Social behavior | Olfaction | Evolution | Social organization | Species | Insectes | Genètica | Research
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8. Full Text P061 Full-length characterisation of 150 novel MICA and MICB alleles
by Albrecht, Viviane and Paech, Christin and Putke, Kathrin and Klasberg, Steffen and Massalski, Carolin and Schöne, Bianca and Fuhrmann, Markus and Schöfl, Gerhard and Schmidt, Alexander and Lange, Vinzenz and Klußmeier, Anja
Human Immunology, ISSN 0198-8859, 09/2019, Volume 80, pp. 98 - 98
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9. Full Text Patterns of non-ARD variation in more than 300 full-length HLA-DPB1 alleles
by Klasberg, Steffen and Lang, Kathrin and Günther, Marie and Schober, Grit and Massalski, Carolin and Schmidt, Alexander H and Lange, Vinzenz and Schöfl, Gerhard
Human Immunology, ISSN 0198-8859, 01/2019, Volume 80, Issue 1, pp. 44 - 52
Our understanding of sequence variation in the HLA-DPB1 gene is largely restricted to the hypervariable antigen recognition domain (ARD) encoded by exon 2.... 
HLA genotyping | Full-length gene sequencing | Novel HLA alleles | DPB1 | HLA | Non-coding variation | DP EXPRESSION | HEMATOPOIETIC-CELL TRANSPLANTATION | VARIANTS | UNRELATED-DONOR | DOCUMENTED HLA ALLELES | IMMUNOLOGY | GENE | COMMON | HEPATITIS-B | ASSOCIATION | Allelomorphism | Transplantation | Histocompatibility antigens | Analysis | Hematopoietic stem cells | HLA histocompatibility antigens
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10. Computational Identification of Novel Genes: Current and Future Perspectives
by Klasberg, Steffen and Bitard-Feildel, Tristan and Mallet, Ludovic
Bioinformatics and Biology Insights, 01/2016, Volume 10, pp. 121 - 131
While it has long been thought that all genomic novelties are derived from the existing material, many genes lacking homology to known genes were found in... 
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11. Computational Identification of Novel Genes: Current and Future Perspectives
by Klasberg, Steffen and Bitard-Feildel, Tristan and Mallet, Ludovic
Bioinformatics and Biology Insights, 01/2016, Volume 10, pp. 121 - 131
While it has long been thought that all genomic novelties are derived from the existing material, many genes lacking homology to known genes were found in... 
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12. Full Text Patterns of non-ARD variation in more than 300 full-length HLA-DPB1 alleles
by Klasberg, Steffen and Lang, Kathrin and Günther, Marie and Schober, Grit and Massalski, Carolin and Schmidt, Alexander H and Lange, Vinzenz and Schöfl, Gerhard
Human immunology, 06/2018
Our understanding of sequence variation in the HLA-DPB1 gene is largely restricted to the hypervariable antigen recognition domain (ARD) encoded by exon 2.... 
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13. Full Text The genomes of two key bumblebee species with primitive eusocial organization
by Sadd, Ben M and Barribeau, Seth M and Bloch, Guy and de Graaf, Dirk C and Dearden, Peter and Elsik, Christine G and Gadau, Jürgen and Grimmelikhuijzen, Cornelis J. P and Hasselmann, Martin and Lozier, Jeffrey D and Robertson, Hugh M and Smagghe, Guy and Stolle, Eckart and Van Vaerenbergh, Matthias and Waterhouse, Robert M and Bornberg-Bauer, Erich and Klasberg, Steffen and Bennett, Anna K and Câmara, Francisco and Guigó, Roderic and Hoff, Katharina and Mariotti, Marco and Munoz-Torres, Monica and Murphy, Terence and Santesmasses, Didac and Amdam, Gro V and Beckers, Matthew and Beye, Martin and Biewer, Matthias and Bitondi, Márcia M. G and Blaxter, Mark L and Bourke, Andrew F. G and Brown, Mark J. F and Buechel, Severine D and Cameron, Rossanah and Cappelle, Kaat and Carolan, James C and Christiaens, Olivier and Ciborowski, Kate L and Clarke, David F and Colgan, Thomas J and Collins, David H and Cridge, Andrew G and Dalmay, Tamas and Dreier, Stephanie and du Plessis, Louis and Duncan, Elizabeth and Erler, Silvio and Evans, Jay and Falcon, Tiago and Flores, Kevin and Freitas, Flávia C. P and Fuchikawa, Taro and Gempe, Tanja and Hartfelder, Klaus and Hauser, Frank and Helbing, Sophie and Humann, Fernanda C and Irvine, Frano and Jermiin, Lars S and Johnson, Claire E and Johnson, Reed M and Jones, Andrew K and Kadowaki, Tatsuhiko and Kidner, Jonathan H and Koch, Vasco and Köhler, Arian and Kraus, F. Bernhard and Lattorff, H. Michael G and Leask, Megan and Lockett, Gabrielle A and Mallon, Eamonn B and Antonio, David S. Marco and Marxer, Monika and Meeus, Ivan and Moritz, Robin F. A and Nair, Ajay and Näpflin, Kathrin and Nissen, Inga and Niu, Jinzhi and Nunes, Francis M. F and Oakeshott, John G and Osborne, Amy and Otte, Marianne and Pinheiro, Daniel G and Rossié, Nina and Rueppell, Olav and Santos, Carolina G and Schmid-Hempel, Regula and Schmitt, Björn D and Schulte, Christina and Simões, Zilá L. P and Soares, Michelle P. M and Swevers, Luc and Winnebeck, Eva C and Wolschin, Florian and Yu, Na and Zdobnov, Evgeny M and Aqrawi, Peshtewani K and Blankenburg, Kerstin P and ...
Genome Biology, ISSN 1465-6906, 2015, Volume 16, Issue 76
BACKGROUND: The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to... 
Biological Sciences | Naturvetenskap | Biologiska vetenskaper | Natural Sciences
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14. Full Text Computational Identification of Novel Genes: Current and Future Perspectives
by Steffen Klasberg and Tristan Bitard-Feildel and Ludovic Mallet
Bioinformatics and Biology Insights, ISSN 1177-9322, 08/2016, Volume 2016, Issue 10, pp. 121 - 131
While it has long been thought that all genomic novelties are derived from the existing material, many genes lacking homology to known genes were found in... 
Evolutionary genomics | Novel domains | Gene detection | Novel genes | De novo genes
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