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1. Full Text Tumor mutational load predicts survival after immunotherapy across multiple cancer types
by Samstein, Robert M and Lee, Chung-Han and Shoushtari, Alexander N and Hellmann, Matthew D and Shen, Ronglai and Janjigian, Yelena Y and Barron, David A and Zehir, Ahmet and Jordan, Emmet J and Omuro, Antonio and Kaley, Thomas J and Kendall, Sviatoslav M and Motzer, Robert J and Hakimi, A. Ari and Voss, Martin H and Russo, Paul and Rosenberg, Jonathan and Iyer, Gopa and Bochner, Bernard H and Bajorin, Dean F and Al-Ahmadie, Hikmat A and Chaft, Jamie E and Rudin, Charles M and Riely, Gregory J and Baxi, Shrujal and Ho, Alan L and Wong, Richard J and Pfister, David G and Wolchok, Jedd D and Barker, Christopher A and Gutin, Philip H and Brennan, Cameron W and Tabar, Viviane and Mellinghoff, Ingo K and DeAngelis, Lisa M and Ariyan, Charlotte E and Lee, Nancy and Tap, William D and Gounder, Mrinal M and D’Angelo, Sandra P and Saltz, Leonard and Stadler, Zsofia K and Scher, Howard I and Baselga, Jose and Razavi, Pedram and Klebanoff, Christopher A and Yaeger, Rona and Segal, Neil H and Ku, Geoffrey Y and DeMatteo, Ronald P and Ladanyi, Marc and Rizvi, Naiyer A and Berger, Michael F and Riaz, Nadeem and Solit, David B and Chan, Timothy A and Morris, Luc G. T
Nature genetics, ISSN 1061-4036, 02/2019, Volume 51, Issue 2, pp. 202 - 206
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Immunotherapy - methods | Neoplasms - therapy | Neoplasms - genetics | Antineoplastic Agents - immunology | Neoplasms - immunology | Humans | Tumor Burden - genetics | High-Throughput Nucleotide Sequencing - methods | Mutation - genetics | Tumor Burden - immunology | Usage | Research | Gene mutations | Immunotherapy | Oncology, Experimental | Cancer | Laboratories | Lung cancer | Melanoma | Histology | Metastasis | Gene expression | Cancer therapies | Patients | Survival | Metastases | Next-generation sequencing | Immune checkpoint | Biomarkers | Mutation | Tumors | Index Medicus
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2. Full Text Paths to stemness: Building the ultimate antitumour T cell
by Gattinoni, Luca and Klebanoff, Christopher A and Restifo, Nicholas P
Nature reviews. Cancer, ISSN 1474-175X, 10/2012, Volume 12, Issue 10, pp. 671 - 684
Life Sciences & Biomedicine | Oncology | Science & Technology | Hematopoietic Stem Cells - immunology | Neoplasms - therapy | Signal Transduction | Neoplasms - immunology | Humans | Hematopoietic Stem Cell Transplantation | Immunologic Memory | T-Lymphocytes - immunology | Cell Differentiation | Adoptive Transfer | T-Lymphocytes - transplantation | Care and treatment | Stem cells | Cellular therapy | Research | Properties | T cells | Health aspects | Tumors | Index Medicus
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3. Full Text Prospects for gene-engineered T cell immunotherapy for solid cancers
by Klebanoff, Christopher A and Rosenberg, Steven A and Restifo, Nicholas P
Nature medicine, ISSN 1078-8956, 01/2016, Volume 22, Issue 1, pp. 26 - 36
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Genetic Engineering - methods | Immunotherapy, Adoptive - methods | Neoplasms - therapy | T-Lymphocytes | Antigens, Neoplasm - immunology | Neoplasms - immunology | Humans | Receptors, Antigen, T-Cell - immunology | Receptors, Antigen, T-Cell - genetics | Adoptive Transfer | Care and treatment | Immunotherapy | Physiological aspects | Genetic aspects | Research | T cells | Methods | Tumors | Antigens | Genetic engineering | T cell receptors | Mutation | Cancer | Index Medicus
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4. Full Text Memory T cell-driven differentiation of naive cells impairs adoptive immunotherapy
by Klebanoff, Christopher A and Scott, Christopher D and Leonardi, Anthony J and Yamamoto, Tori N and Cruz, Anthony C and Ouyang, Claudia and Ramaswamy, Madhu and Roychoudhuri, Rahul and Ji, Yun and Eil, Robert L and Sukumar, Madhusudhanan and Crompton, Joseph G and Palmer, Douglas C and Borman, Zachary A and Clever, David and Thomas, Stacy K and Patel, Shashankkumar and Yu, Zhiya and Muranski, Pawel and Liu, Hui and Wang, Ena and Marincola, Francesco M and Gros, Alena and Gattinoni, Luca and Rosenberg, Steven A and Siegel, Richard M and Restifo, Nicholas P
The Journal of clinical investigation, ISSN 0021-9738, 01/2016, Volume 126, Issue 1, pp. 318 - 334
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Immunotherapy, Adoptive | Melanoma, Experimental - therapy | Mice, Inbred C57BL | Proto-Oncogene Proteins c-akt - physiology | Fas Ligand Protein - physiology | Animals | T-Lymphocytes - cytology | Female | Immunologic Memory | T-Lymphocytes - immunology | Cell Differentiation | Mice | fas Receptor - physiology | Genetic aspects | Research | Cell differentiation | Immunotherapy | Cells | T cells | Health aspects | Antigens | Medical research | Flow cytometry | Clinical trials | T cell receptors | Genomes | Kinases | Gene expression | Experiments | Patients | Lymphocytes | Population | Software | Charitable foundations | Cancer | Index Medicus | Abridged Index Medicus
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5. Full Text T cell receptor‐based cancer immunotherapy: Emerging efficacy and pathways of resistance
by Chandran, Smita S and Klebanoff, Christopher A
Immunological reviews, ISSN 0105-2896, 07/2019, Volume 290, Issue 1, pp. 127 - 147
TCR mimic | ImmTAC | CRISPR/Cas9 | adoptive immunotherapy | genetic engineering | Life Sciences & Biomedicine | Immunology | Science & Technology | Immunotherapy, Adoptive - adverse effects | Neoplasms - metabolism | Immunotherapy, Adoptive - methods | Receptors, Antigen, T-Cell - metabolism | Antigens, Neoplasm - immunology | Humans | Treatment Outcome | Clinical Studies as Topic | Neoplasms - therapy | Animals | Genetic Engineering | T-Lymphocytes - metabolism | Neoplasms - immunology | Receptors, Chimeric Antigen - genetics | T-Cell Antigen Receptor Specificity | T-Lymphocytes - immunology | Receptors, Antigen, T-Cell - genetics | Receptors, Chimeric Antigen - metabolism | Care and treatment | Immunotherapy | Genetically modified organisms | Genetic engineering | Drug therapy | T cells | Cancer | Antigenic determinants | Antigens | Innovations | Clinical trials | Universe | T cell receptors | Genomes | Lymphocytes T | Epitopes | T-cell receptor | Chimeric antigen receptors | Receptors | Immune checkpoint | Lymphocytes | Recognition | Cytoplasm | Index Medicus | CRISPR | Invited Reviews | Cas9 | Invited Review
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