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1. Incidence, risk factors, and attributable mortality of secondary infections in the intensive care unit after admission for sepsis
by Van Vught, Lonneke A. V and Klouwenberg, Peter M. C. Klein and Spitoni, Cristian and Scicluna, Brendon P and Wiewel, Maryse A and Horn, Janneke and Schultz, Marcus J and Nürnberg, Peter and Bonten, Marc J. M and Cremer, Olaf L and Van Der Poll, Tom and MARS Consortium
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 04/2016, Volume 315, Issue 14, pp. 1469 - 1479
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Prospective Studies | Genomics | Humans | Middle Aged | Cross Infection - mortality | Intensive Care Units - statistics & numerical data | Male | Sepsis - complications | Gene Expression Profiling | Cross Infection - immunology | Incidence | Netherlands | Female | Catheter-Related Infections - epidemiology | Length of Stay - statistics & numerical data | Cross Infection - epidemiology | Severity of Illness Index | Sepsis - immunology | Hospital Mortality | Risk Factors | Shock, Septic - complications | Shock, Septic - mortality | Sepsis - genetics | Sepsis - mortality | Survival Analysis | Organ Dysfunction Scores | Aged | APACHE | Clinical trials | Sepsis | Intensive care | Mortality
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2. Full Text Epidemiology of Multiple Herpes Viremia in Previously Immunocompetent Patients With Septic Shock
by Ong, David S. Y and Bonten, Marc J. M and Spitoni, Cristian and Verduyn Lunel, Frans M and Frencken, Jos F and Horn, Janneke and Schultz, Marcus J and van der Poll, Tom and Klein Klouwenberg, Peter M. C and Cremer, Olaf L and Mol Diag Risk Stratification Sepsi and Molecular Diagnosis and Risk Stratification of Sepsis Consortium
Clinical infectious diseases, ISSN 1058-4838, 2017, Volume 64, Issue 9, pp. 1204 - 1210
Cmegalovirus | Reactivation | Epstein-Barr virus | Human herpesvirus 6 | Mortality | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Herpesviridae - isolation & purification | Intensive Care Units | Prospective Studies | Shock, Septic - etiology | Tertiary Care Centers | Humans | Middle Aged | Shock, Septic - epidemiology | Herpesviridae Infections - complications | Male | Herpesviridae Infections - virology | Viremia - complications | Netherlands | Viremia - virology | Viremia - epidemiology | Female | Aged | Herpesviridae - classification | Herpesviridae Infections - epidemiology | Hospital patients | Septic shock | Research | Herpesviruses | Epidemiology | Health aspects | Risk factors | Viremia | Immunodeficiency | Herpes simplex | Viruses | Patients | Confidence intervals | Polymerase chain reaction | Herpes viruses | Varicella | Sepsis | Adults | Index Medicus
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3. Full Text The attributable mortality of delirium in critically ill patients: prospective cohort study
by Klein Klouwenberg, Peter M C and Zaal, Irene J and Spitoni, Cristian and Ong, David S Y and van der Kooi, Arendina W and Bonten, Marc J M and Slooter, Arjen J C and Cremer, Olaf L
BMJ : British Medical Journal, ISSN 0959-8138, 11/2014, Volume 349, Issue nov24 16, pp. g6652 - g6652
RESEARCH | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Prospective Studies | Hospital Mortality | Humans | Middle Aged | Netherlands - epidemiology | Intensive Care Units - statistics & numerical data | Logistic Models | Male | Critical Illness - mortality | Survival Analysis | Critical Care | Female | Aged | Delirium - mortality | Odds Ratio | Length of Stay - statistics & numerical data | Index Medicus | Abridged Index Medicus
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4. Full Text Comparative Analysis of the Host Response to Community-acquired and Hospital-acquired Pneumonia in Critically Ill Patients
by van Vught, Lonneke A and Scicluna, Brendon P and Wiewel, Maryse A and Hoogendijk, Arie J and Klein Klouwenberg, Peter M. C and Franitza, Marek and Toliat, Mohammad R and Nürnberg, Peter and Cremer, Olaf L and Horn, Janneke and Schultz, Marcus J and Bonten, Marc M. J and van der Poll, Tom
American journal of respiratory and critical care medicine, ISSN 1073-449X, 2016, Volume 194, Issue 11, pp. 1366 - 1374
Sepsis | Pneumonia | Critically Ill | Genomics | Intensive care unit | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Severity of Illness Index | Prospective Studies | Humans | Middle Aged | Critical Illness | Pneumonia - immunology | Female | Male | Cross Infection - immunology | Community-Acquired Infections - immunology | Index Medicus | Abridged Index Medicus
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5. Full Text Epidemiology, Management, and Risk-Adjusted Mortality of ICU-Acquired Enterococcal Bacteremia
by David S. Y. Ong and Marc J. M. Bonten and Khatera Safdari and Cristian Spitoni and Jos F. Frencken and Esther Witteveen and Janneke Horn and Peter M. C. Klein Klouwenberg and Olaf L. Cremer and MARS Consortium and MARS consortium
Clinical infectious diseases, ISSN 1058-4838, 11/2015, Volume 61, Issue 9, pp. 1413 - 1420
ARTICLES AND COMMENTARIES | mortality | bloodstream infection | intensive care unit | enterococcus | bacteremia | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Intensive Care Units | Prospective Studies | Humans | Middle Aged | Mortality | Netherlands - epidemiology | Bacteremia - drug therapy | Cross Infection - mortality | Gram-Positive Bacterial Infections - mortality | Bacteremia - mortality | Male | Bacteremia - diagnosis | Gram-Positive Bacterial Infections - diagnosis | Cross Infection - drug therapy | Gram-Positive Bacterial Infections - epidemiology | Enterococcus - isolation & purification | Aged, 80 and over | Cross Infection - diagnosis | Adult | Bacteremia - epidemiology | Female | Aged | Gram-Positive Bacterial Infections - drug therapy | Cross Infection - epidemiology | Enterococcus | Intensive care units | Care and treatment | Analysis | Research | Management | Epidemiology | Bacteremia | Gram-positive bacteria | Fatalities | Intensive care | Bacterial infections | Disease management | Index Medicus
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6. Full Text Cytomegalovirus reactivation and mortality in patients with acute respiratory distress syndrome
by Ong, David S. Y and Spitoni, Cristian and Klein Klouwenberg, Peter M. C and Verduyn Lunel, Frans M and Frencken, Jos F and Schultz, Marcus J and van der Poll, Tom and Kesecioglu, Jozef and Bonten, Marc J. M and Cremer, Olaf L
Intensive care medicine, ISSN 0342-4642, 2016, Volume 42, Issue 3, pp. 333 - 341
Pediatrics | Cytomegalovirus | Pain Medicine | Reactivation | Emergency Medicine | Pneumology/Respiratory System | Medicine & Public Health | Viremia | Mortality | Intensive / Critical Care Medicine | Anesthesiology | ARDS | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Prospective Studies | Humans | Middle Aged | Netherlands - epidemiology | Risk Factors | Male | Respiratory Distress Syndrome, Adult - mortality | Respiration, Artificial | Cytomegalovirus Infections - mortality | Respiratory Distress Syndrome, Adult - virology | Female | Aged | APACHE | Acute respiratory distress syndrome | Care and treatment | Genetic aspects | Research | Cytomegaloviruses | Risk factors | Virus diseases | Medical research | Netherlands | Respiratory distress syndrome | Patient outcomes | Analysis | Medicine, Experimental | Cytomegalovirus infections | United Kingdom | Index Medicus | Original
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7. Full Text Short-Course Adjunctive Gentamicin as Empirical Therapy in Patients With Severe Sepsis and Septic Shock: A Prospective Observational Cohort Study
by Ong, David S. Y and Frencken, Jos F and Klein Klouwenberg, Peter M. C and Juffermans, Nicole and van der Poll, Tom and Bonten, Marc J. M and Cremer, Olaf L and MARS Consortium and MARS consortium
Clinical infectious diseases, ISSN 1058-4838, 2017, Volume 64, Issue 12, pp. 1731 - 1736
gentamicin | mortality | renal failure | acute kidney injury | sepsis | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Intensive Care Units | Prospective Studies | Tertiary Care Centers | Gentamicins - therapeutic use | Hospital Mortality | Humans | Middle Aged | Logistic Models | Male | Sepsis - complications | Gentamicins - administration & dosage | Shock, Septic - mortality | Sepsis - mortality | Anti-Bacterial Agents - therapeutic use | Gram-Negative Bacteria - drug effects | Sepsis - drug therapy | Drug Resistance, Multiple, Bacterial | Multiple Organ Failure - etiology | Shock, Septic - drug therapy | Female | Aged | Anti-Bacterial Agents - pharmacology | Anti-Bacterial Agents - administration & dosage | Cohort Studies | Anti-infective agents | Sepsis | Care and treatment | Dosage and administration | Kidney failure | Gentamicin | Index Medicus
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8. Full Text Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patients
by Claushuis, Theodora A. M and van Vught, Lonneke A and Scicluna, Brendon P and Wiewel, Maryse A and Klein Klouwenberg, Peter M. C and Hoogendijk, Arie J and Ong, David S. Y and Cremer, Olaf L and Horn, Janneke and Franitza, Marek and Toliat, Mohammad R and Nürnberg, Peter and Zwinderman, Aeilko H and Bonten, Marc J and Schultz, Marcus J and van der Poll, Tom and Mol Diag Risk Stratification Sepsi and Molecular Diagnosis and Risk Stratification of Sepsis Consortium
Blood, ISSN 0006-4971, 2016, Volume 127, Issue 24, pp. 3062 - 3072
Life Sciences & Biomedicine | Hematology | Science & Technology | Intensive Care Units | Prognosis | Humans | Middle Aged | Sepsis - diagnosis | Male | Sepsis - complications | Biomarkers - blood | Case-Control Studies | Thrombocytopenia - blood | Thrombocytopenia - complications | Sepsis - mortality | Critical Illness - mortality | Platelet Count | Survival Analysis | Thrombocytopenia - mortality | Adult | Female | Thrombocytopenia - diagnosis | Aged | Sepsis - blood | Cytokines - blood | Index Medicus | Abridged Index Medicus
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9. Full Text Chronic antiplatelet therapy is not associated with alterations in the presentation, outcome, or host response biomarkers during sepsis: a propensity-matched analysis
by Wiewel, Maryse A and de Stoppelaar, Sacha F and van Vught, Lonneke A and Frencken, Jos F and Hoogendijk, Arie J and Klein Klouwenberg, Peter M. C and Horn, Janneke and Bonten, Marc J and Zwinderman, Aeilko H and Cremer, Olaf L and Schultz, Marcus J and van der Poll, Tom and MARS Consortium and On behalf of the MARS Consortium
Intensive care medicine, ISSN 0342-4642, 2016, Volume 42, Issue 3, pp. 352 - 360
no | Pediatrics | Pain Medicine | Antiplatelet | Emergency Medicine | Pneumology/Respiratory System | Medicine & Public Health | Mortality | Intensive / Critical Care Medicine | Sepsis | Anesthesiology | Intensive care unit | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Intensive Care Units | Prospective Studies | Humans | Middle Aged | Male | Biomarkers - blood | Aspirin - administration & dosage | Propensity Score | Netherlands | Platelet Aggregation Inhibitors - administration & dosage | Female | Aged | Sepsis - blood | Intensive care units | Care and treatment | Research | Management | Biological markers | Medicine, Experimental | Medical research | Hospitals | Analysis | Index Medicus | Original
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10. Full Text Classification of sepsis, severe sepsis and septic shock: the impact of minor variations in data capture and definition of SIRS criteria
by Klein Klouwenberg, Peter M. C and Ong, David S. Y and Bonten, Marc J. M and Cremer, Olaf L
Intensive care medicine, ISSN 0342-4642, 5/2012, Volume 38, Issue 5, pp. 811 - 819
Pediatrics | Emergency Medicine | Intensive / Critical Care Medicine | Epidemiology | Intensive care unit | Pain Medicine | Pneumology/Respiratory System | Systemic inflammatory response syndrome | Medicine & Public Health | Sepsis | Clinical trial | Anesthesiology | Diagnosis | Epidemiology Diagnosis | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | Intensive care medicine | Emergency and intensive care: infection, septic shock | Medical sciences | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Intensive Care Units | Prospective Studies | Bias | Humans | Middle Aged | Netherlands - epidemiology | Shock, Septic - epidemiology | Male | Shock, Septic - classification | Multiple Organ Failure - classification | Monitoring, Physiologic - methods | Female | Aged | Care and treatment | Critical care medicine | Research | Index Medicus
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11. Full Text A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission
by Scicluna, Brendon P and Klein Klouwenberg, Peter M. C and van Vught, Lonneke A and Wiewel, Maryse A and Ong, David S. Y and Zwinderman, Aeilko H and Franitza, Marek and Toliat, Mohammad R and Nürnberg, Peter and Hoogendijk, Arie J and Horn, Janneke and Cremer, Olaf L and Schultz, Marcus J and Bonten, Marc J and van der Poll, Tom
American journal of respiratory and critical care medicine, ISSN 1073-449X, 2015, Volume 192, Issue 7, pp. 826 - 835
Sepsis | Biomarker | Pneumonia | Microarray | Blood | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Calcitonin Gene-Related Peptide | Community-Acquired Infections - diagnosis | Calcitonin - blood | Intensive Care Units | Protein Precursors - blood | Tissue Array Analysis | Humans | Middle Aged | Male | Gene Expression Profiling | Biomarkers - blood | Proteins - genetics | Interleukin-6 - blood | Pneumonia - diagnosis | Apoptosis Regulatory Proteins - genetics | Female | Aged | Interleukin-8 - blood | Index Medicus | Abridged Index Medicus
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