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Nature Biotechnology, ISSN 1087-0156, 01/2015, Volume 33, Issue 3, pp. 306 - 312
Journal Article
Nature, ISSN 0028-0836, 10/2017, Volume 550, Issue 7677, pp. 534 - 538
The ubiquitin system regulates essential cellular processes in eukaryotes. Ubiquitin is ligated to substrate proteins as monomers or chains and the topology of... 
DEUBIQUITINATING ENZYME | MULTIDISCIPLINARY SCIENCES | LINKED UBIQUITIN | Pyridines - chemistry | Ubiquitin-Specific Peptidase 7 - chemistry | Humans | Ubiquitin - metabolism | Substrate Specificity | Tumor Suppressor Protein p53 - genetics | Aminopyridines - chemistry | Ubiquitin-Specific Peptidase 7 - deficiency | Proto-Oncogene Proteins c-pim-1 - antagonists & inhibitors | Female | Proto-Oncogene Proteins c-mdm2 - metabolism | Phenols - pharmacology | Binding, Competitive | Indazoles - chemistry | Tumor Suppressor Protein p53 - metabolism | Ubiquitin - chemistry | Models, Molecular | Neoplasms - enzymology | Ubiquitin-Specific Peptidase 7 - antagonists & inhibitors | Ubiquitin-Specific Peptidase 7 - metabolism | Mice, SCID | Tumor Suppressor Protein p53 - deficiency | Neoplasms - drug therapy | Drug Synergism | Indazoles - pharmacology | Animals | Aminopyridines - pharmacology | Cell Line, Tumor | Protein Binding | Phenols - chemistry | Mice | Pyridines - pharmacology | Neoplasms - pathology | Biological research | Physiological aspects | Chemical inhibitors | Research | Ubiquitin-proteasome system | Biology, Experimental | Ubiquitin | Nuclear magnetic resonance--NMR | Toxicity | Hydrogen | p53 Protein | Cytotoxicity | Chains | Kinases | Monomers | Proteins | Depolymerization | Eukaryotes | Ubiquitination | Cell cycle | Reaction kinetics | Catalysis | Crystal structure | Binding | Enzymes | Magnetic resonance | Topology | Substrates | Chemotherapy | Inhibitors | Cell death | Proteasomes | Resonance | Mutation | Kinetics | Cancer | Tumors
Journal Article
BMC Bioinformatics, 11 (Suppl 10), 2010, ISSN 1471-2105, 12/2010, Volume 11, Issue 10, pp. I1 - I1
This meeting report gives an overview of the keynote lectures and a selection of the student oral and poster presentations at the 6th International Society for... 
Journal Article
Nature Genetics, ISSN 1061-4036, 08/2017, Volume 49, Issue 8, pp. 1219 - 1230
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2018, Volume 13, Issue 6, p. e0199264
Journal Article
Cancer Research, ISSN 0008-5472, 11/2015, Volume 75, Issue 22 Supplement 1, pp. A1 - A1-19
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 04/2017, Volume 16, Issue 4, pp. 694 - 704
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 398 - 398
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2013, Volume 110, Issue 21, pp. 8632 - 8637
Germ-line mutations in PALB2 lead to a familial predisposition to breast and pancreatic cancer or to Fanconi Anemia subtype N. PALB2 performs its tumor... 
Genomics | Cell lines | Alleles | Breast cancer | Breast neoplasms | Mice | Embryos | Genetic mutation | Tumors | Cancer | Mouse model | Familial breast cancer | EARLY EMBRYONIC LETHALITY | mouse model | SOLID TUMORS | MULTIDISCIPLINARY SCIENCES | CRE RECOMBINASE | FANCONI-ANEMIA | MOUSE MODELS | GENOMIC INSTABILITY | BRCA1 DEFICIENCY | SUSCEPTIBILITY GENE | familial breast cancer | HOMOLOGOUS RECOMBINATION | CELLULAR PROLIFERATION | Neoplastic Syndromes, Hereditary - pathology | Humans | Neoplastic Syndromes, Hereditary - metabolism | Mammary Neoplasms, Experimental - metabolism | Mammary Neoplasms, Experimental - genetics | Tumor Suppressor Protein p53 - genetics | Breast Neoplasms - metabolism | Mice, Mutant Strains | BRCA1 Protein - metabolism | Gene Deletion | Tumor Suppressor Proteins - genetics | Mammary Neoplasms, Experimental - pathology | Female | Neoplastic Syndromes, Hereditary - genetics | Nuclear Proteins - genetics | Fanconi Anemia Complementation Group N Protein | Disease Models, Animal | Rad51 Recombinase - metabolism | Tumor Suppressor Proteins - metabolism | Rad51 Recombinase - genetics | Tumor Suppressor Protein p53 - metabolism | Nuclear Proteins - metabolism | BRCA1 Protein - genetics | Animals | BRCA2 Protein - metabolism | Breast Neoplasms - genetics | Breast Neoplasms - pathology | BRCA2 Protein - genetics | Prevention | Tumor suppressor genes | Genetic aspects | Health aspects | Biological Sciences
Journal Article