X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
cancer (5) 5
apoptosis (3) 3
cell cycle (3) 3
cytotoxicity (3) 3
drug resistance (3) 3
index medicus (3) 3
pharmacology & pharmacy (3) 3
bacteria (2) 2
cysteine (2) 2
derivatives (2) 2
drug resistance in microorganisms (2) 2
expression (2) 2
fluorescence polarization (2) 2
glycoprotein (2) 2
humans (2) 2
inhibition (2) 2
inhibitors (2) 2
kinetics (2) 2
ligands (2) 2
p-glycoprotein (2) 2
polo-like kinase (2) 2
proteins (2) 2
toxicity (2) 2
tumors (2) 2
3,4-dihydroisocoumarin (1) 1
4-dihydroisocoumarin (1) 1
abc transporter (1) 1
acute lymphocytic leukemia (1) 1
adenosine triphosphatase (1) 1
aldehyde inhibitors (1) 1
alzheimers disease (1) 1
alzheimers-disease (1) 1
amino acid sequence (1) 1
anaerobic respiration (1) 1
analogs (1) 1
antifungal activity (1) 1
antifungal agents - pharmacology (1) 1
antifungal resistance (1) 1
antineoplastic agents - administration & dosage (1) 1
antineoplastic agents - chemistry (1) 1
antineoplastic agents - pharmacology (1) 1
apoe genotype (1) 1
assaying (1) 1
atp-binding cassette transporters - antagonists & inhibitors (1) 1
atp-binding protein (1) 1
atrophy (1) 1
azole resistance (1) 1
bacillus - genetics (1) 1
bacillus - growth & development (1) 1
bacillus - metabolism (1) 1
bacillus megaterium - genetics (1) 1
bacillus subtilis - genetics (1) 1
bacillus subtilis - growth & development (1) 1
bacterial proteins - chemistry (1) 1
bacterial proteins - genetics (1) 1
bacteriology (1) 1
beta catenin - genetics (1) 1
beta catenin - metabolism (1) 1
binding cassette transporters (1) 1
biological evaluation (1) 1
biomarkers (1) 1
biotechnology (1) 1
breast cancer resistance protein (1) 1
cancer chemotherapy (1) 1
cancer-cells (1) 1
candida albicans (1) 1
candida albicans - drug effects (1) 1
candida albicans - metabolism (1) 1
care and treatment (1) 1
casings or constructional details of electric apparatus (1) 1
cathepsin k - antagonists & inhibitors (1) 1
cathepsin k - chemistry (1) 1
cell adhesion & migration (1) 1
cell death (1) 1
cell line, tumor (1) 1
cell lines (1) 1
cell migration (1) 1
cell-division (1) 1
cellular signal transduction (1) 1
chemical synthesis (1) 1
chemistry, medicinal (1) 1
chemosensitization (1) 1
classification (1) 1
clinical isolates (1) 1
cognitive ability (1) 1
collateral sensitivity (1) 1
combinatorial analysis (1) 1
combinatorial chemistry (1) 1
compound a (1) 1
conversion (1) 1
cortex (1) 1
cortical feature (1) 1
corticalfeature (1) 1
crystal-structure (1) 1
csf biomarkers (1) 1
cysteine proteases (1) 1
databases, factual (1) 1
dementia (1) 1
dentistry (1) 1
design (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Investigational New Drugs, ISSN 0167-6997, 2019, pp. 1 - 9
PLK1 has an important role in the regulation of cell cycle and represents an important target for cancer treatment. This enzyme belongs to the Polo-like... 
Targeted chemotherapy, PLK | Drug screening | Neoplasms | Cell cycle | Apoptosis | Fluorescence polarization | Polo-like kinase 1 | Toxicity | Leukemia | Fluorescence | Cytotoxicity | Selectivity | Lead compounds | Drug resistance | Kinases | Medical screening | Molecular docking | Proteins | Organic chemistry | Inhibitors | Cell death | Polo-like kinase | Cancer
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 12/2017, Volume 146, p. 63
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.bcp.2017.10.008 Multidrug... 
Phosphates | Drug resistance in microorganisms | Cysteine | Surface active agents | Cellular signal transduction | Acute lymphocytic leukemia | Sulfates | T cells | Adenosine triphosphatase
Journal Article
Investigational New Drugs, ISSN 0167-6997, 06/2019, pp. 1 - 12
SummaryVitamin K3, also known as menadione, is a synthetic lipid-soluble 2-methyl-1,4- naphthoquinone analogs of vitamin K. The vitamin K derivatives exhibit... 
Migration inhibition | Flow cytometry | Biotechnology | Toxicity | p53 Protein | Cytotoxicity | Lipids | Doxorubicin | Cell adhesion & migration | Analogs | Mitochondria | Tubulin | Cell cycle | Inhibition | P-Glycoprotein | Inducers | Vitamin K | Menadione | Tumor cells | Glycoprotein | Tumor cell lines | Derivatives | Suppressors | Tau protein | Cell lines | Predictions | ATP-binding protein | Cell migration | Cancer | Apoptosis | Tumors
Journal Article
Journal Article
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 04/2019, Volume 10, p. 400
Journal Article
ACTA PHARMACEUTICA SINICA B, ISSN 2211-3835, 09/2019, Volume 9, Issue 5, pp. 1021 - 1034
Polo-like kinase (PLK1) has been identified as a potential target for cancer treatment. Although a number of small molecules have been investigated as PLK1... 
APOPTOSIS | FLUORESCENCE POLARIZATION | POLO-LIKE-KINASE-1 | Polo box domain | PLK1 | Spindle damage | FOXO TRANSCRIPTION FACTORS | CANCER | CELL-DIVISION | RESISTANT | Necroptosis | PATHWAY | Cell cycle | Polo-like kinase | PHARMACOLOGY & PHARMACY | Mono-targeted therapy | REGULATORS
Journal Article
Investigational new drugs, 06/2019
Vitamin K , also known as menadione, is a synthetic lipid-soluble 2-methyl-1,4- naphthoquinone analogs of vitamin K. The vitamin K derivatives exhibit potent... 
Journal Article
PLoS ONE, 05/2015, Volume 10, Issue 5
Objective To identify a novel class of inhibitors of fungal transporters involved in drug resistance. Methods A series of structurally-related low molecular... 
Journal Article
by Guo, Shengwen and Lai, Chunren and Wu, Congling and Cen, Guiyin and Hariharan, A and Vijayakumari, Anupa A and Aarabi, Mohammad Hadi and Aballi, John and Nour, Abd Elazeim Abd Alla Mohamed and Abdelaziz, Mohammed and Abdolalizadeh, AmirHussein and Abdollahi, Mahsa and Abdul Aziz, Siti Aishah and Salam, Amritha Abdul and Abdulaziz, Nidhal and Abdulkadir, Ahmed and Abdullah, Sachal and Abdullah, Osama and Abrigo, Jill and Adachi, Noriaki and Adamson, Christopher and Adduru, Viraj and Adel, Tameem and Aderghal, Karim and Ades-Aron, Benjamin and Adeyosoye, Michael and Adlard, Paul and Srinivasa, Ag and Aganj, Iman and Agarwal, Ayush and Agarwal, Anupam and Agarwal, Anchit and Aguero, Cinthya and Aguiar, Pablo and Ahdidan, Jamila and Ahmad, Fayyaz and Ahmad, Rziwan and Ahmadi, Hessam and Ahmed, Nisar and Sid, Farid Ahmed and Ai, Edward and Ai, Qing and Aicha, Benyahia and Aitharaju, Sai and Aiyer, Aditya and Akkus, Zeynettin and Akodad, Sanae and Akramifard, Hamid and Aksman, Leon and Aktas, Said and Al-Janabi, Omar and Al-Nuaimi, Ali and AlAila, BahaaEddin and Alakwaa, Fadhl and Alam, Saruar and Alam, Fakhre and Alam Zaidi, Syed Farhan and Alan, Wiener and Alansari, Mukhtar and Alareqi, Ebrahim and Alberdi, Ane and Albsoul, Mohammad and Alderson, Thomas and Aleem, Hassan and Alex, Aishwarya and Alexander, Jacob and Alexopoulos, Panagiotis and Alfoldi, Jessica and Ali, Ayesha and Ali, Imdad and Alimoradian, Shirin and Aljabar, Paul and Aljabbouli, Hasan and Aljovic, Almir and Allen, Genevera and Alliende, Luz Maria and Almaguel, Frankis and Almgren, Hannes and Montes, Carmen Alonso and Alowaisheq, Tasneem and Alryalat, Saif Aldeen and Alsado, Majd and Alsaedi, Abdalrahman and Alshehri, Haifa and Altaf, Tooba and Altendahl, Marie and Altmann, Ane and Alvand, Ashkan and Filho, Manoel Alves and Alzubi, Raid and Amaral, Robert and Ambatipudi, Mythri and Amernath, Remya and Amlien, Inge and Amoroso, Nicola and Amri, Hakima and Anastasiou, Athanasios and Anbarasi, Jani and Anbarjafari, Gholamreza and Anderson, Wes and ... and Alzheimer's Dis Neuroimaging and Alzheimer's Disease Neuroimaging Initiative and The Alzheimer's Disease Neuroimaging Initiative
Frontiers in aging neuroscience, ISSN 1663-4365, 2017, Volume 9, Issue MAY, pp. 146 - 146
Journal Article