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FEMS Microbiology Letters, ISSN 0378-1097, 05/2011, Volume 318, Issue 2, pp. 168 - 176
The antipsychotic drug thioridazine is a candidate drug for an alternative treatment of infections caused by methicillin-resistant Staphylococcus aureus (MRSA)... 
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2017, Volume 12, Issue 3, p. e0173362
Introduction Conservative treatment solutions against aortic prosthetic vascular graft infection (APVGI) for inoperable patients are limited. The combination... 
DIAGNOSIS | ANTIBIOTICS | EFFLUX PUMP | MANAGEMENT | METABOLISM | EFFICACY | ENANTIOMERS | MULTIDISCIPLINARY SCIENCES | RESISTANCE | PREVENTION | POLYESTER | Staphylococcal Infections - drug therapy | Thioridazine - adverse effects | Thioridazine - therapeutic use | Body Temperature - drug effects | Staphylococcus aureus - physiology | Body Weight - drug effects | Hemoglobins - metabolism | Vascular Grafting - adverse effects | Haptoglobins - metabolism | Drug Synergism | Dicloxacillin - therapeutic use | Animals | Time Factors | Swine | Thioridazine - pharmacology | Dicloxacillin - pharmacology | Female | Leukocyte Count | Dicloxacillin - adverse effects | Staphylococcus aureus - drug effects | Staphylococcal Infections - blood | Disease Models, Animal | Staphylococcal Infections - metabolism | Care and treatment | Dicloxacillin | Thioridazine | Staphylococcus aureus infections | Dosage and administration | Research | Drug therapy, Combination | Health aspects | Prostheses | Surgical implants | Temperature | Infections | Statistical methods | Antibacterial materials | Experiments | Grafting | Synergism | Blood | Methicillin | Psychotropic drugs | Inoculation | Aorta | Doublecortin protein | Bacteria | Pigs | Vascular surgery | Statistical analysis | Staphylococcus infections | Antimicrobial agents | Pharmacology | Metabolism | Statistics | Hogs | Biofilms | Grafts | Antibiotics | Samples | Coronary vessels | Viability
Journal Article
PLoS ONE, 08/2015, Volume 10, Issue 8
Introduction The rise in antimicrobial resistance is a major global concern and requires new treatment strategies. The use of helper compounds, such as... 
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e64518
Subinhibitory concentrations of the neuroleptic drug thioridazine (TDZ) are well-known to enhance the killing of methicillin-resistant Staphylococcus aureus... 
MYCOBACTERIUM-TUBERCULOSIS | TEICHOIC-ACIDS | IN-VITRO | MULTIDISCIPLINARY SCIENCES | ENTEROCOCCUS-FAECIUM | CROSS-LINKING | 2-COMPONENT SYSTEM | LACTAM ANTIBIOTIC-RESISTANCE | PEPTIDOGLYCAN COMPOSITION | PHENOTHIAZINE-DERIVATIVES | STRESS STIMULON | Linear Models | Penicillin-Binding Proteins - metabolism | Microbial Sensitivity Tests | Peptidoglycan - biosynthesis | Gene Expression Regulation, Bacterial - drug effects | Methicillin-Resistant Staphylococcus aureus - metabolism | Cell Wall - drug effects | Glycine - pharmacology | Microarray Analysis | Thioridazine - pharmacology | Cell Wall - metabolism | Antipsychotic Agents - pharmacology | Methicillin-Resistant Staphylococcus aureus - genetics | beta-Lactam Resistance - drug effects | Proteins | Drug resistance in microorganisms | DNA microarrays | Genes | Physiological aspects | Beta lactamases | Glycine | Gene expression | Staphylococcus aureus | Protein binding | Phenothiazine | Drugs | Transcription | Laboratories | Pathogenesis | Amino acids | Amides | Biochemistry | Biosynthesis | Drug resistance | Pentaglycine | Methicillin | Penicillin | Bacteria | Killing | β-Lactam antibiotics | Prokaryotes | Cell walls | Peptidoglycans | Staphylococcus infections | Antimicrobial agents | Substrates | Thioridazine | Antibiotics | Antimicrobial resistance | Molecular biology
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 11/2016, Volume 241, pp. 125 - 134
Journal Article
The New Microbiologica, ISSN 1121-7138, 04/2017, Volume 40, Issue 2, p. 146
We have previously shown that the phenothiazine, thioridazine, acts in synergy with the beta-lactam antibiotic, dicloxacillin, to kill methicillin-resistant... 
Dicloxacillin | β-Lactam antibiotics | Cell walls | Gram-positive bacteria | Staphylococcus infections | Amides | Vancomycin | Drug resistance | Methicillin | Thioridazine | Antibiotics | Penicillin | Thickening | Phenothiazine
Journal Article
FEMS Microbiology Letters, ISSN 0378-1097, 05/2011, Volume 318, Issue 2, pp. 168 - 176
Journal Article
PLoS ONE, 05/2013, Volume 8, Issue 5
Subinhibitory concentrations of the neuroleptic drug thioridazine (TDZ) are well-known to enhance the killing of methicillin-resistant Staphylococcus aureus... 
Journal Article
Nucleic Acid Therapeutics, ISSN 2159-3337, 12/2018, Volume 28, Issue 6, pp. 348 - 356
Journal Article