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Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 07/2014, Volume 136, Issue 26, pp. 9308 - 9319
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2007, Volume 104, Issue 51, pp. 20523 - 20528
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2015, Volume 112, Issue 34, pp. 10768 - 10773
Th17 responses are critical to a variety of human autoimmune diseases, and therapeutic targeting with monoclonal antibodies against IL-17 and IL-23 has shown... 
Epigenetic inhibitors | Bromodomain | Th17 | CBP/p300 | Ankylosing spondylitis | RHEUMATOID-ARTHRITIS | CELLS | epigenetic inhibitors | EFFICACY | P300 | MULTIDISCIPLINARY SCIENCES | ankylosing spondylitis | CRYSTALLOGRAPHY | ANKYLOSING-SPONDYLITIS | BINDING PROTEIN | bromodomain | LIGANDS | DOUBLE-BLIND | BET BROMODOMAINS | p300-CBP Transcription Factors - antagonists & inhibitors | Humans | Middle Aged | Crystallography, X-Ray | Male | Structure-Activity Relationship | Benzimidazoles - chemistry | Th17 Cells - drug effects | Arthritis, Psoriatic - pathology | Adult | Female | Molecular Structure | Drug Evaluation, Preclinical | Immunosuppressive Agents - pharmacology | Arthritis, Psoriatic - metabolism | Recombinant Proteins - metabolism | Interleukin-17 - secretion | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Interleukin-17 - genetics | Models, Molecular | Interleukin-17 - biosynthesis | Isoxazoles - chemistry | Spondylitis, Ankylosing - metabolism | Azepines - pharmacology | Gene Expression Regulation - drug effects | Isoxazoles - pharmacology | Triazoles - pharmacology | Th17 Cells - immunology | Benzimidazoles - pharmacology | Calorimetry | Protein Conformation | Aged | Kinetics | Spondylitis, Ankylosing - pathology | CD4-Positive T-Lymphocytes - drug effects | Immunosuppressive Agents - chemistry | Protein Structure, Tertiary - drug effects | Immune response | Development and progression | Genetic aspects | Genetic transcription | Binding proteins | Properties | Autoimmune diseases | Health aspects | CBP | p300 | Biological Sciences
Journal Article
Cancer Research, ISSN 0008-5472, 12/2015, Volume 75, Issue 23, pp. 5106 - 5119
Journal Article
Current Opinion in Structural Biology, ISSN 0959-440X, 12/2009, Volume 19, Issue 6, pp. 643 - 649
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 07/2015, Volume 11, Issue 8, pp. 536 - 541
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 2014, Volume 10, Issue 4, pp. 305 - 312
Journal Article