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1. Full Text Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes
by Zhao, Na and Liu, Chia-Chen and Van Ingelgom, Alexandra J and Martens, Yuka A and Linares, Cynthia and Knight, Joshua A and Painter, Meghan M and Sullivan, Patrick M and Bu, Guojun
Neuron (Cambridge, Mass.), ISSN 0896-6273, 09/2017, Volume 96, Issue 1, pp. 115 - 129.e5
Aggregation | Endosomal dysfunction | Alzheimer’s disease | Trafficking | Aging | APOE | Insulin signaling | Alzheimer's disease | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Apolipoprotein E4 - genetics | Apolipoprotein E4 - metabolism | Insulin - physiology | Male | Mice, Transgenic | Neurons - cytology | Endosomes - metabolism | Mice, Knockout | Glycolysis - physiology | Apolipoprotein E3 - genetics | Animals | Aging - physiology | Insulin Resistance - physiology | Diet, High-Fat | Cell Respiration - physiology | Neurons - physiology | Female | Receptor, Insulin - metabolism | Mice | Neurons - metabolism | Primary Cell Culture | Mitochondria - physiology | Aging - metabolism | Insulin resistance | Apolipoproteins | Neurons | Insulin | Medical research | Medical colleges | Nervous system diseases | Medicine, Experimental | Risk factors | Brain | Pathogenesis | Clinical trials | Nervous system | Glucose | Kinases | High fat diet | Signal transduction | Mitochondria | Rodents | Shinto | Amyloid | Protein transport | Age | Apolipoprotein E4 | Neurodegenerative diseases | Diabetes mellitus | Metabolism | Studies | Musculoskeletal system | Trapping | Glycolysis | Diabetes | Electron transport | Endosomes | Dementia | Index Medicus
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2. Full Text Analysis of a blockstream in the northern Lesotho Drakensberg, southern Africa
by Bregman, Alexandra and Knight, Jasper
Quaternary international, ISSN 1040-6182, 07/2020
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3. Full Text A communal catalogue reveals Earth's multiscale microbial diversity
by Thompson, Luke R and Sanders, Jon G and McDonald, Daniel and Amir, Amnon and Ladau, Joshua and Locey, Kenneth J and Prill, Robert J and Tripathi, Anupriya and Gibbons, Sean M and Ackermann, Gail and Navas-Molina, Jose A and Janssen, Stefan and Kopylova, Evguenia and Vazquez-Baeza, Yoshiki and Gonzalez, Antonio and Morton, James T and Mirarab, Siavash and Xu, Zhenjiang Zech and Jiang, Lingjing and Haroon, Mohamed F and Kanbar, Jad and Zhu, Qiyun and Song, Se Jin and Kosciolek, Tomasz and Bokulich, Nicholas A and Lefler, Joshua and Brislawn, Colin J and Humphrey, Gregory and Owens, Sarah M and Hampton-Marcell, Jarrad and Berg-Lyons, Donna and McKenzie, Valerie and Fierer, Noah and Fuhrman, Jed A and Clauset, Aaron and Stevens, Rick L and Shade, Ashley and Pollard, Katherine S and Goodwin, Kelly D and Jansson, Janet K and Gilbert, Jack A and Knight, Rob and Earth Microbiome Project Consortiu and Earth Microbiome Project Consortium and The Earth Microbiome Project Consortium and Argonne National Lab. (ANL), Argonne, IL (United States) and Pacific Northwest National Lab. (PNNL), Richland, WA (United States) and Naturvetenskapliga fakulteten and Faculty of Sciences and Göteborgs universitet and Gothenburg University and Institutionen för marina vetenskaper and Department of marine sciences
Nature (London), ISSN 0028-0836, 11/2017, Volume 551, Issue 7681, pp. 457 - +
CONSISTENT | ARCHAEAL | EVOLUTION | MARINE BACTERIAL | GLOBAL PATTERNS | BACTERIAL DIVERSITY | OPERON COPY NUMBER | ONTOLOGY | COMMUNITIES | NESTEDNESS | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Humans | RNA, Ribosomal, 16S - analysis | Geographic Mapping | Plants - microbiology | Gene Dosage | Archaea - isolation & purification | Biodiversity | Bacteria - genetics | Bacteria - isolation & purification | Ecology - methods | Animals | Microbiota - genetics | RNA, Ribosomal, 16S - genetics | Archaea - genetics | Earth, Planet | Environmental aspects | Observations | Microbial colonies | Biological diversity | International marketing | Nucleotide sequencing | Ribosomal RNA | Catalogs | Analysis | DNA sequencing | Microbiological research | Distribution | Genetic aspects | Research | Identification and classification | Analytical methods | Nucleotide sequence | Microbiology | Taxonomy | rRNA | Ecology | Genomes | Ribonucleic acid--RNA | Gene sequencing | Meta-analysis | Earth | Studies | Microorganisms | Phylogenetics | Bacteria | Deoxyribonucleic acid--DNA | Index Medicus | ENVIRONMENTAL SCIENCES | global | BASIC BIOLOGICAL SCIENCES | microbiome | Geosciences, Multidisciplinary | Climate Research | Klimatforskning | Oceanografi, hydrologi, vattenresurser | Oceanography, Hydrology, Water Resources | Annan geovetenskap och miljövetenskap | Multidisciplinär geovetenskap | Ekologi | Other Earth and Related Environmental Sciences | CVI Infection Biology | CVI Infectiebiologie | Food Quality and Design | VLAG | Infectiebiologie | Infection Biology
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4. Full Text Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
by East-Seletsky, Alexandra and O'Connell, Mitchell R and Knight, Spencer C and Burstein, David and Cate, Jamie H. D and Tjian, Robert and Doudna, Jennifer A
Nature (London), ISSN 0028-0836, 2016, Volume 538, Issue 7624, pp. 270 - 273
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | CRISPR-Associated Proteins - chemistry | RNA, Guide - genetics | Ribonucleases - chemistry | RNA, Guide - metabolism | Leptotrichia - enzymology | RNA Cleavage | CRISPR-Cas Systems - genetics | Ribonucleases - metabolism | Base Sequence | CRISPR-Associated Proteins - metabolism | RNA, Bacterial - genetics | Clustered Regularly Interspaced Short Palindromic Repeats - genetics | RNA, Bacterial - metabolism | RNA sequencing | Methods | Proteins | Enzymes | Mutation | Ribonucleic acid--RNA | Index Medicus
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5. Full Text Arts-Research-Education
: Connections and Directions
by Knight, Linda and Lasczik Cutcher, Alexandra
2017, Studies in Arts-Based Educational Research, ISBN 9783319615592, Volume 1, 276
Arts-Study and teaching
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6. Full Text APOE ε2 is associated with increased tau pathology in primary tauopathy
by Zhao, Na and Liu, Chia-Chen and Van Ingelgom, Alexandra J and Linares, Cynthia and Kurti, Aishe and Knight, Joshua A and Heckman, Michael G and Diehl, Nancy N and Shinohara, Mitsuru and Martens, Yuka A and Attrebi, Olivia N and Petrucelli, Leonard and Fryer, John D and Wszolek, Zbigniew K and Graff-Radford, Neill R and Caselli, Richard J and Sanchez-Contreras, Monica Y and Rademakers, Rosa and Murray, Melissa E and Koga, Shunsuke and Dickson, Dennis W and Ross, Owen A and Bu, Guojun
Nature communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 4388 - 11
Apolipoprotein E4 - metabolism | Supranuclear Palsy, Progressive - pathology | Humans | Tauopathies - pathology | Apolipoprotein E2 - metabolism | Disease Progression | Alzheimer Disease - pathology | Tauopathies - metabolism | Animals | Alleles | Alzheimer Disease - metabolism | Supranuclear Palsy, Progressive - metabolism | Mice | Supranuclear Palsy, Progressive - genetics | Gene transfer | Neurodegenerative diseases | Abnormalities | Transgenic mice | Health risks | Viruses | Inflammation | Risk analysis | Risk factors | Pathology | Genotype & phenotype | Tau protein | Neurodegeneration | Apolipoprotein E | Progressive supranuclear palsy | Rodents | Degeneration | Paralysis | Genotypes | Index Medicus
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7. Full Text Weak Te,Te Interactions through the Looking Glass of NMR Spin–Spin Coupling
by Bühl, Michael and Knight, Fergus R and Křístková, Anezka and Malkin Ondík, Irina and Malkina, Olga L and Randall, Rebecca A. M and Slawin, Alexandra M. Z and Woollins, J. Derek
Angewandte Chemie (International ed.), ISSN 1433-7851, 02/2013, Volume 52, Issue 9, pp. 2495 - 2498
tellurium | naphthalenes | quantum‐chemical computation | through‐bond interactions | through‐space interactions | quantum-chemical computation | through-space interactions | through-bond interactions | Universities and colleges | Nuclear magnetic resonance | Naphthalene | Glass | Electronics | Joining | Derivatives | Bonding | Tellurium | Spin-spin coupling | Communications
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8. Full Text Bayesian inference for psychology. Part II: Example applications with JASP
by Wagenmakers, E.-J and Love, J and Marsman, M and Jamil, T and Ly, A and Verhagen, J and Selker, R and Gronau, Q.F and pmann, D and Boutin, B and Meerhoff, F and Knight, P and Raj, A and van Kesteren, E.-J and van Doorn, J and Šmíra, M and Epskamp, S and Etz, A and Matzke, D and de Jong, T and van den Bergh, D and Sarafoglou, A and Steingroever, H and Derks, K and Rouder, J.N and Morey, R.D
Psychonomic bulletin & review, ISSN 1069-9384, 02/2018, Volume 25, Issue 1, pp. 58 - 76
Hypothesis test | Arts and Humanities (miscellaneous) | Developmental and Educational Psychology | Experimental and Cognitive Psychology | Statistical evidence | Bayes factor | Posterior distribution | Cognitive Psychology | Psychology | Software | Research Design | Humans | Bayes Theorem | Parameter estimation | Theory | Science | Statistical methods | Psychologists | Experiments | Variance analysis | Software packages | Researchers | User interface | Software upgrading | Preferences | Bayesian analysis | Philosophy | Open access | Index Medicus | Brief Report
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9. Full Text Investigating silver coordination to mixed chalcogen ligands
by Knight, Fergus R and Randall, Rebecca A.M and Wakefield, Lucy and Slawin, Alexandra M.Z and Woollins, J. Derek
Molecules (Basel, Switzerland), ISSN 1420-3049, 11/2012, Volume 17, Issue 11, pp. 13307 - 13329
Acenaphthene ligands | Coordination networks | Helical chain polymer | Silver(I) complexes | Chalcogen-donor | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Selenium - chemistry | Molecular Conformation | Chelating Agents - chemistry | Coordination Complexes - chemical synthesis | Models, Molecular | Crystallography, X-Ray | Tellurium - chemistry | Mesylates - chemistry | Borates - chemistry | Acenaphthenes - chemistry | Coordination Complexes - chemistry | Silver Compounds - chemistry | Index Medicus | silver(I) complexes | chalcogen-donor | helical chain polymer | acenaphthene ligands | coordination networks
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10. Full Text New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism
by Horikoshi, Momoko and Yaghootkar, Hanieh and Mook-Kanamori, Dennis O and Sovio, Ulla and Taal, H. Rob and Hennig, Branwen J and Bradfield, Jonathan P and St Pourcain, Beate and Evans, David M and Charoen, Pimphen and Kaakinen, Marika and Cousminer, Diana L and Lehtimaki, Terho and Kreiner-Moller, Eskil and Warrington, Nicole M and Bustamante, Mariona and Feenstra, Bjarke and Berry, Diane J and Thiering, Elisabeth and Pfab, Thiemo and Barton, Sheila J and Shields, Beverley M and Kerkhof, Marjan and van Leeuwen, Elisa and Fulford, Anthony J and Kutalik, Zoltan and Zhao, Jing Hua and den Hoed, Marcel and Mahajan, Anubha and Lindi, Virpi and Goh, Liang-Kee and Hottenga, Jouke-Jan and Wu, Ying and Raitakari, Olli T and Harder, Marie N and Meirhaeghe, Aline and Ntalla, Ioanna and Salem, Rany M and Jameson, Karen A and Zhou, Kaixin and Monies, Dorota M and Lagou, Vasiliki and Kirin, Mirna and Heikkinen, Jani and Adair, Linda S and Alkuraya, Fowzan S and Al-Odaib, Ali and Amouyel, Philippe and Postma, Dirkje S and Koppelman, Gerard H and Early Growth Genetics EGG and MAGIC and Early Growth Genetics (EGG) Consortium and Meta-Analyses of Glucose- and Insulin-related traits Consortium (MAGIC) and The Meta-Analyses of Glucose- and Insulin-related traits Consortium (MAGIC)
Nature genetics, ISSN 1061-4036, 01/2013, Volume 45, Issue 1, pp. 76 - 82
FASTING GLUCOSE | INDIVIDUALS | COMMON VARIANTS | METAANALYSIS | SUSCEPTIBILITY LOCI | TYPE-2 DIABETES RISK | BLOOD-PRESSURE |