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2013, ACS symposium series, ISBN 9780841227828, Volume 1131, xi, 429
Book
Handbook of experimental pharmacology, ISSN 0171-2004, 03/2019, Volume 254, pp. 323 - 343
The nociceptin/orphanin FQ peptide (NOP) receptor-related ligands have been demonstrated in preclinical studies for several therapeutic applications. This... 
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 10/2012, Volume 343, Issue 1, pp. 72 - 81
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 07/2013, Volume 346, Issue 1, pp. 11 - 22
Nociceptin/orphanin FQ peptide receptor (NOP) agonists produce antinociceptive effects in animal models after spinal administration and potentiate μ-opioid... 
Narcotic Antagonists - administration & dosage | Male | Receptors, Opioid, mu - agonists | Indoles - administration & dosage | Buprenorphine - analogs & derivatives | Azabicyclo Compounds - therapeutic use | Neurons - metabolism | Disease Models, Animal | Phenalenes - therapeutic use | Receptors, Opioid, mu - metabolism | Azabicyclo Compounds - administration & dosage | Nerve Tissue Proteins - agonists | Drug Tolerance | Phenalenes - adverse effects | Analgesics, Opioid - therapeutic use | Spinal Cord - immunology | Hyperalgesia - immunology | Buprenorphine - administration & dosage | Buprenorphine - therapeutic use | Indoles - adverse effects | Buprenorphine - adverse effects | Indoles - therapeutic use | Ligands | Mice | Receptors, Opioid - agonists | Spinal Cord - drug effects | Spinal Cord - metabolism | Anesthesia, Spinal - methods | Neuralgia - metabolism | Dose-Response Relationship, Drug | Anesthesia, Spinal - adverse effects | Analgesics, Opioid - adverse effects | Neurons - drug effects | Azabicyclo Compounds - adverse effects | Receptors, Opioid - metabolism | Injections, Spinal | Nerve Tissue Proteins - antagonists & inhibitors | Molecular Targeted Therapy - adverse effects | Hyperalgesia - metabolism | Neurons - immunology | Narcotic Antagonists - adverse effects | Receptors, Opioid, mu - antagonists & inhibitors | Mice, Inbred ICR | Neuralgia - drug therapy | Nerve Tissue Proteins - metabolism | Animals | Hyperalgesia - drug therapy | Narcotic Antagonists - therapeutic use | Analgesics, Opioid - administration & dosage | Phenalenes - administration & dosage | Index Medicus | Behavioral Pharmacology
Journal Article
08/2019, Handbook of Experimental Pharmacology, ISBN 3030201856, Volume 254, 412
eBook
Drug and Alcohol Dependence, ISSN 0376-8716, 2016, Volume 171, pp. e106 - e106
Journal Article
2008, AD-a486 620.
These experiments demonstrated that (1) intrathecal N/OFQ did not produced hyperalgesia-like effects as reported in rodents, (2) systemic Ro 64-6198 produced... 
monkeys | primates | receptor sites(physiology) | pharmacology | analgesics | behavior | activation | rodents
Government Document
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, pp. e67422 - e67422
Pruritus (itch) is a severe side effect associated with the use of drugs as well as hepatic and hematological disorders. Previous studies in rodents suggest... 
MU-OPIOID RECEPTORS | DORSAL-HORN NEURONS | RESPONSES | INTRATHECAL MORPHINE | RANDOMIZED-TRIALS | BOMBESIN | POSTCESAREAN ANALGESIA | PRURITUS | MULTIDISCIPLINARY SCIENCES | RATS | HISTAMINE | Spinal Cord - drug effects | Motor Activity - drug effects | Male | Peptide Fragments - pharmacology | Gastrin-Releasing Peptide - administration & dosage | Bombesin - administration & dosage | Indoles - administration & dosage | Bombesin - pharmacology | Bombesin - analogs & derivatives | Spinal Cord - pathology | Gastrin-Releasing Peptide - antagonists & inhibitors | Behavior, Animal - drug effects | Indoles - pharmacology | Injections, Spinal | Pyridines - administration & dosage | Gastrin-Releasing Peptide - pharmacology | Morphine - pharmacology | Peptide Fragments - administration & dosage | Pruritus - metabolism | Receptors, Bombesin - metabolism | Animals | Mice | Pyridines - pharmacology | Pruritus - pathology | Morphine - administration & dosage | Physiological aspects | Morphine | Bombesin | Pruritus | Gastrin | Drugs | Spinal cord | Animal models | Peptides | Liver | Gallbladder diseases | Receptors | Rodents | Opioids | Scratching | Physiology | Behavior | Pretreatment | Drug dosages | Scratching behavior | Hematology | Narcotics | Neurons | Pharmacology | Gastrin-releasing peptide | Side effects | Receptor mechanisms | Anesthesiology | Laboratory animals | Neurotransmission | Neuromedin | Index Medicus
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2016, Volume 113, Issue 37, pp. E5511 - E5518
Despite the critical need, no previous research has substantiated safe opioid analgesics without abuse liability in primates. Recent advances in medicinal... 
Physical dependence | Mu opioid peptide receptor | Reinforcing effects | Respiratory depression | N/ofq peptide receptor | N/OFQ peptide receptor | UNITED-STATES | respiratory depression | CHRONIC PAIN | RHESUS-MONKEYS | RECEPTOR AGONISTS | MULTIDISCIPLINARY SCIENCES | NOCICEPTIN/ORPHANIN FQ PEPTIDE | PROGRESSIVE-RATIO SCHEDULES | NOP | mu opioid peptide receptor | BUPRENORPHINE | reinforcing effects | INFLAMMATORY PAIN | physical dependence | CAPSAICIN | Analgesics, Opioid - antagonists & inhibitors | Humans | Buprenorphine - metabolism | Receptors, Opioid, mu - agonists | Receptors, Opioid, mu - antagonists & inhibitors | Respiratory Insufficiency - chemically induced | Opioid Peptides - agonists | Pain - pathology | Drug-Related Side Effects and Adverse Reactions - pathology | Analgesics, Opioid - agonists | Respiratory Insufficiency - pathology | Buprenorphine - administration & dosage | Analgesics, Opioid - adverse effects | Animals | Analgesics, Opioid - administration & dosage | Cocaine - toxicity | Opioid Peptides - antagonists & inhibitors | Pain - drug therapy | Buprenorphine - adverse effects | Buprenorphine - analogs & derivatives | Buprenorphine - chemistry | Primates | Ligands | Analgesics | Peptides | Narcotics | Monkeys & apes | Index Medicus | Biological Sciences | PNAS Plus | N | OFQ peptide receptor
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 09/2016, Volume 113, Issue 37, p. 10236
Journal Article
ACS Symposium Series, ISSN 0097-6156, 2013, Volume 1131, pp. 393 - 416
Conference Proceeding
Science Translational Medicine, ISSN 1946-6234, 08/2018, Volume 10, Issue 456, p. eaar3483
Misuse of prescription opioids, opioid addiction, and overdose underscore the urgent need for developing addiction-free effective medications for treating... 
UNITED-STATES | MEDICINE, RESEARCH & EXPERIMENTAL | INDUCED HYPERALGESIA | LIGANDS | RHESUS-MONKEYS | MORPHINE | ABUSE LIABILITY | INDUCED ITCH | PROGRESSIVE-RATIO SCHEDULES | INFLAMMATORY PAIN | FQ PEPTIDE RECEPTORS | CELL BIOLOGY | Index Medicus
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 09/2008, Volume 130, Issue 36, pp. 12148 - 12155
Journal Article
Acta Dermato-Venereologica, ISSN 0001-5555, 05/2019, Volume 99, Issue 6, pp. 587 - 593
Neuromedin B is expressed in nociceptive and itchsensitive dorsal root ganglia neurons, but its peripheral pruritogenic potential is not well described. The... 
Neuromedin B | Acute itch | Mast cells | Dorsal root ganglia | Allergic dermatitis | dorsal root ganglia | MECHANISMS | GASTRIN-RELEASING-PEPTIDE | mast cells | DERMATOLOGY | allergic dermatitis | RESPONSES | IN-VITRO | CANINE ATOPIC-DERMATITIS | PHARMACOLOGY | INFLAMMATION | neuromedin B | acute itch | HISTAMINE | RECEPTORS | MODULATION | dorsal root ganglia, mast cells
Journal Article
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