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Nature, ISSN 0028-0836, 06/2017, Volume 546, Issue 7657, pp. 248 - 253
Journal Article
Science, ISSN 0036-8075, 11/2007, Volume 318, Issue 5854, pp. 1258 - 1265
Heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors constitute the largest family of eukaryotic signal transduction proteins that... 
Proteins | Molecules | Receptors | Crystals | Data collection | Ligands | Lipids | Cell membranes | Research Articles | Cholesterols | Crystal structure
Journal Article
Cell, ISSN 0092-8674, 01/2013, Volume 152, Issue 3, pp. 532 - 542
G-protein-coupled receptors (GPCRs) can modulate diverse signaling pathways, often in a ligand-specific manner. The full range of functionally relevant... 
Biophysics and Computational biology | Biological sciences | Pharmacology
Journal Article
Nature, ISSN 0028-0836, 03/2016, Volume 531, Issue 7594, pp. 335 - 340
Journal Article
Science, ISSN 0036-8075, 11/2007, Volume 318, Issue 5854, pp. 1266 - 1273
The β₂-adrenergic receptor (β₂AR) is a well-studied prototype for heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors (GPCRs) that... 
Proteins | Molecules | Receptors | Drug interactions | Crystallization | Crystals | Agonists | Ligands | Amino acids | Research Articles | Crystal structure
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2017, Volume 114, Issue 8, pp. 2066 - 2071
The adenosine A receptor (A R) has long been implicated in cardiovascular disorders. As more selective A R ligands are being identified, its roles in other... 
A2A adenosine receptor | Allosteric | GPCR | Parkinson's disease | Structure | allosteric | 60 APPLIED LIFE SCIENCES | structure | Parkinson’s disease | Biological Sciences
Journal Article
Nature, ISSN 0028-0836, 01/2010, Volume 463, Issue 7277, pp. 108 - 112
Journal Article
Cell, ISSN 0092-8674, 05/2015, Volume 161, Issue 5, pp. 1101 - 1111
G-protein-coupled receptors (GPCRs) transduce signals from the extracellular environment to intracellular proteins. To gain structural insight into the... 
Journal Article
Nature, ISSN 0028-0836, 01/2011, Volume 469, Issue 7329, pp. 175 - 181
G protein coupled receptors (GPCRs) exhibit a spectrum of functional behaviors in response to natural and synthetic ligands. Recent crystal structures provide... 
Journal Article
NATURE, ISSN 0028-0836, 01/2011, Volume 469, Issue 7329, pp. 175 - 180
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 02/2017, Volume 114, Issue 8, pp. 2066 - 2071
The adenosine A(2A) receptor (A(2A)R) has long been implicated in cardiovascular disorders. As more selective A(2A)R ligands are being identified, its roles in... 
allosteric | COMPLEX | Parkinson's disease | MEMBRANE | MULTIDISCIPLINARY SCIENCES | HIGH-AFFINITY | structure | SOFTWARE | FEATURES | A2A adenosine receptor | PROTEIN-COUPLED RECEPTOR | GPCR | ZM241385 | DERIVATIVES | PARKINSONS-DISEASE
Journal Article