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Journal Article
Journal Article
BMC IMMUNOLOGY, ISSN 1471-2172, 07/2019, Volume 20, Issue 1, pp. 25 - 12
BackgroundIn this study, seven adjuvants were compared for use with Plasmodium falciparum DiCo-Apical Membrane Antigen 1 (Pf-DiCo-AMA1), with the aim to... 
APICAL MEMBRANE ANTIGEN-1 | ANTIBODIES | Rabbits | AMA1 | CoVaccine HT (TM) | RECOGNITION | SE-GLA | Liposomes-GLA | Adjuvants | IMMUNOLOGY | MALARIA VACCINE CANDIDATE | Plasmodium falciparum | ImSaVac-P | INHIBITION | IMMUNE-RESPONSES | ESTERS | Liposomes | Prevention | Usage | Malaria | Pregnant women | Analysis | Malaria vaccine | Clinical trials | Research | Health aspects | Risk factors
Journal Article
Malaria Journal, ISSN 1475-2875, 12/2019, Volume 18, Issue 1, pp. 1 - 23
Historically neglected, due to its biological peculiarities, the absence of a continuous long-term in vitro blood stage culture system and a propensity towards... 
Plasmodium falciparum | Malaria | Health aspects | Mortality | Plasmodium vivax | Medium | Continuous long-term blood-stage culture
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 504, Issue 7479, pp. 248 - 253
Achieving the goal of malaria elimination will depend on targeting Plasmodium pathways essential across all life stages. Here we identify a lipid kinase,... 
YEAST | TRANSMISSION | POTENT | VIVAX | PHOSPHATIDYLINOSITOL 4-PHOSPHATE | FALCIPARUM | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | KINASE | ZINC-FINGER NUCLEASES | SACCHAROMYCES-CEREVISIAE | Plasmodium - enzymology | Phosphatidylinositol Phosphates - metabolism | Humans | Male | rab GTP-Binding Proteins - genetics | Macaca mulatta | Plasmodium - drug effects | Hepatocytes - parasitology | 1-Phosphatidylinositol 4-Kinase - metabolism | Quinoxalines - pharmacology | Schizonts - cytology | Adenosine Triphosphate - metabolism | Plasmodium - growth & development | Female | Binding Sites | Fatty Acids - metabolism | Cytokinesis - drug effects | Imidazoles - metabolism | Life Cycle Stages - drug effects | Pyrazoles - pharmacology | 1-Phosphatidylinositol 4-Kinase - genetics | rab GTP-Binding Proteins - metabolism | 1-Phosphatidylinositol 4-Kinase - chemistry | Reproducibility of Results | Models, Molecular | 1-Phosphatidylinositol 4-Kinase - antagonists & inhibitors | Drug Resistance - drug effects | Imidazoles - pharmacology | Quinoxalines - metabolism | Pyrazoles - metabolism | Schizonts - drug effects | Drug Resistance - genetics | Animals | Models, Biological | Malaria - parasitology | Malaria - drug therapy | Plasmodium - classification | Plasma | Mosquitoes | Malaria | Licenses | Infections | Parasites | Kinases | Drug dosages
Journal Article
Trends in Parasitology, ISSN 1471-4922, 12/2017, Volume 33, Issue 12, pp. 921 - 924
The recent research efforts to establish a continuous, long-term blood-stage culture have focused on the ideal host cell type. However, this is only part of... 
Plasmodium vivax - growth & development | Animals | Humans | Cells, Cultured | Cell Culture Techniques | Erythrocytes - parasitology | Life Cycle Stages | Medical colleges | Emergency medicine
Journal Article
Nature, ISSN 0028-0836, 2016, Volume 538, Issue 7625, pp. 344 - 349
Antimalarial drugs have thus far been chiefly derived from two sources-natural products and synthetic drug-like compounds. Here we investigate whether... 
IN-VITRO | TRANSFER-RNA SYNTHETASE | MALARIA CONTROL | PLASMODIUM-FALCIPARUM | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | LIVER | TARGETS | PROTEIN-SYNTHESIS | NEXT-GENERATION | HEPATIC STAGES | Azabicyclo Compounds - pharmacology | Plasmodium falciparum - enzymology | Malaria, Falciparum - prevention & control | Male | Plasmodium falciparum - cytology | Azetidines - pharmacology | Plasmodium falciparum - drug effects | Cytosol - enzymology | Malaria, Falciparum - transmission | Liver - drug effects | Azabicyclo Compounds - chemical synthesis | Azabicyclo Compounds - therapeutic use | Female | Safety | Antimalarials - chemical synthesis | Disease Models, Animal | Life Cycle Stages - drug effects | Malaria, Falciparum - drug therapy | Azabicyclo Compounds - administration & dosage | Azetidines - adverse effects | Phenylurea Compounds - therapeutic use | Antimalarials - therapeutic use | Macaca mulatta - parasitology | Phenylalanine-tRNA Ligase - antagonists & inhibitors | Drug Discovery | Antimalarials - pharmacology | Animals | Azetidines - administration & dosage | Phenylurea Compounds - chemical synthesis | Antimalarials - administration & dosage | Azetidines - therapeutic use | Phenylurea Compounds - administration & dosage | Mice | Phenylurea Compounds - pharmacology | Liver - parasitology | Plasmodium falciparum - growth & development | Prevention | Antimalarials | Disease transmission | Health aspects | Transfer RNA | Proteins | Cytochrome | Malaria | Liver | Parasites | Kinases | Drug resistance | Drug dosages
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2012, Volume 109, Issue 21, pp. 8298 - 8303
Journal Article
Journal Article