Lancet, The, ISSN 0140-6736, 2014, Volume 384, Issue 9958, pp. 1929 - 1935
Summary Background Alteplase is effective for treatment of acute ischaemic stroke but debate continues about its use after longer times since stroke onset, in...
Internal Medicine | MEDICINE, GENERAL & INTERNAL | TISSUE-PLASMINOGEN-ACTIVATOR | ATLANTIS | ECASS | POOLED ANALYSIS | EPITHET | NINDS | Acute Disease | Age Factors | Time-to-Treatment | Humans | Middle Aged | Male | Tissue Plasminogen Activator - administration & dosage | Treatment Outcome | Stroke - drug therapy | Tissue Plasminogen Activator - adverse effects | Randomized Controlled Trials as Topic | Fibrinolytic Agents - adverse effects | Clinical Trials, Phase III as Topic | Intracranial Hemorrhages - chemically induced | Intracranial Hemorrhages - mortality | Aged, 80 and over | Female | Aged | Fibrinolytic Agents - administration & dosage | Infusions, Intravenous | Stroke - mortality | Stroke (Disease) | Complications and side effects | Dosage and administration | Drug therapy | Tissue plasminogen activator | Patient outcomes | Stroke | FDA approval | Mortality | Age | Clinical outcomes
Internal Medicine | MEDICINE, GENERAL & INTERNAL | TISSUE-PLASMINOGEN-ACTIVATOR | ATLANTIS | ECASS | POOLED ANALYSIS | EPITHET | NINDS | Acute Disease | Age Factors | Time-to-Treatment | Humans | Middle Aged | Male | Tissue Plasminogen Activator - administration & dosage | Treatment Outcome | Stroke - drug therapy | Tissue Plasminogen Activator - adverse effects | Randomized Controlled Trials as Topic | Fibrinolytic Agents - adverse effects | Clinical Trials, Phase III as Topic | Intracranial Hemorrhages - chemically induced | Intracranial Hemorrhages - mortality | Aged, 80 and over | Female | Aged | Fibrinolytic Agents - administration & dosage | Infusions, Intravenous | Stroke - mortality | Stroke (Disease) | Complications and side effects | Dosage and administration | Drug therapy | Tissue plasminogen activator | Patient outcomes | Stroke | FDA approval | Mortality | Age | Clinical outcomes
Journal Article
Lancet Neurology, The, ISSN 1474-4422, 2016, Volume 15, Issue 9, pp. 925 - 933
Summary Background Randomised trials have shown that alteplase improves the odds of a good outcome when delivered within 4·5 h of acute ischaemic stroke....
Neurology | INTRAVENOUS THROMBOLYSIS | THERAPY | TISSUE-PLASMINOGEN-ACTIVATOR | THROMBECTOMY | SYMPTOM ONSET | ATLANTIS | RANDOMIZED-TRIAL | CLINICAL NEUROLOGY | TENECTEPLASE | Brain Ischemia - complications | Cerebral Hemorrhage - chemically induced | Age Factors | Outcome Assessment (Health Care) | Humans | Middle Aged | Databases, Factual - statistics & numerical data | Logistic Models | Male | Stroke - drug therapy | Tissue Plasminogen Activator - adverse effects | Randomized Controlled Trials as Topic | Fibrinolytic Agents - adverse effects | Stroke - etiology | Cerebral Hemorrhage - epidemiology | Time Factors | Aged, 80 and over | Adult | Female | Aged | Stroke (Disease) | Neurosciences | Ischemia | Tissue plasminogen activator | Mortality | Health aspects | Epidemiology | Stroke | Blood pressure | Medical imaging | Hemorrhage | Collaboration
Neurology | INTRAVENOUS THROMBOLYSIS | THERAPY | TISSUE-PLASMINOGEN-ACTIVATOR | THROMBECTOMY | SYMPTOM ONSET | ATLANTIS | RANDOMIZED-TRIAL | CLINICAL NEUROLOGY | TENECTEPLASE | Brain Ischemia - complications | Cerebral Hemorrhage - chemically induced | Age Factors | Outcome Assessment (Health Care) | Humans | Middle Aged | Databases, Factual - statistics & numerical data | Logistic Models | Male | Stroke - drug therapy | Tissue Plasminogen Activator - adverse effects | Randomized Controlled Trials as Topic | Fibrinolytic Agents - adverse effects | Stroke - etiology | Cerebral Hemorrhage - epidemiology | Time Factors | Aged, 80 and over | Adult | Female | Aged | Stroke (Disease) | Neurosciences | Ischemia | Tissue plasminogen activator | Mortality | Health aspects | Epidemiology | Stroke | Blood pressure | Medical imaging | Hemorrhage | Collaboration
Journal Article
Journal of Cell Science, ISSN 0021-9533, 2015, Volume 128, Issue 13, pp. 2244 - 2258
Epithelial apicobasal polarity has fundamental roles in epithelial physiology and morphogenesis. The PAR complex, comprising PAR-3, PAR-6 and atypical protein...
Apicobasal polarity | AP-2 | Gαi3 | Transcription | Girdin | PAR-aPKC complex | G alpha i3 | PROTEIN-KINASE-C | SPINDLE POSITION | G-ALPHA | CAENORHABDITIS-ELEGANS EMBRYOS | TIGHT JUNCTION | CELL BIOLOGY | BREAST-CANCER | PROSTATE-CANCER CELLS | ADHERENS JUNCTIONS | CYTOCHALASIN-D | LUMEN FORMATION | Cell Polarity | Epithelial Cells - metabolism | Humans | Molecular Sequence Data | RNA, Messenger - metabolism | Transcription Factor AP-2 - metabolism | Protein Kinase C - metabolism | Base Sequence | Madin Darby Canine Kidney Cells | Transcription, Genetic | Epithelial Cells - cytology | Microfilament Proteins - genetics | Tight Junctions - metabolism | Signal Transduction | RNA, Messenger - genetics | Vesicular Transport Proteins - genetics | Gene Expression Regulation | Cell Communication | Rats | Hep G2 Cells | Animals | Carrier Proteins - metabolism | Dogs | Protein Binding | HeLa Cells | GTP-Binding Protein alpha Subunits, Gi-Go - metabolism
Apicobasal polarity | AP-2 | Gαi3 | Transcription | Girdin | PAR-aPKC complex | G alpha i3 | PROTEIN-KINASE-C | SPINDLE POSITION | G-ALPHA | CAENORHABDITIS-ELEGANS EMBRYOS | TIGHT JUNCTION | CELL BIOLOGY | BREAST-CANCER | PROSTATE-CANCER CELLS | ADHERENS JUNCTIONS | CYTOCHALASIN-D | LUMEN FORMATION | Cell Polarity | Epithelial Cells - metabolism | Humans | Molecular Sequence Data | RNA, Messenger - metabolism | Transcription Factor AP-2 - metabolism | Protein Kinase C - metabolism | Base Sequence | Madin Darby Canine Kidney Cells | Transcription, Genetic | Epithelial Cells - cytology | Microfilament Proteins - genetics | Tight Junctions - metabolism | Signal Transduction | RNA, Messenger - genetics | Vesicular Transport Proteins - genetics | Gene Expression Regulation | Cell Communication | Rats | Hep G2 Cells | Animals | Carrier Proteins - metabolism | Dogs | Protein Binding | HeLa Cells | GTP-Binding Protein alpha Subunits, Gi-Go - metabolism
Journal Article
Current Applied Physics, ISSN 1567-1739, 01/2020, Volume 20, Issue 1, pp. 191 - 195
We investigated the effect of hydrogen dilution on the Si cluster volume fraction of hydrogenated amorphous films by varying the hydrogen dilution ratio at...
Silicon cluster | Dilution | Multi-hollow electrode | PECVD | Hydrogen | Silicon film
Silicon cluster | Dilution | Multi-hollow electrode | PECVD | Hydrogen | Silicon film
Journal Article
JAPANESE JOURNAL OF APPLIED PHYSICS, ISSN 0021-4922, 06/2019, Volume 58, Issue SE, p. SE0802
Dramatic advances are being made in dry processing technologies. Atomic scale precision below 10 nm is now possible with fine patterning technologies for...
SELECTIVE SIO2 | CYCLOTRON-RESONANCE PLASMA | PHYSICS, APPLIED | POLYMER-FILM DEPOSITION | MECHANISM | REDUCTION | SILICON | HOLES | PROFILE EVOLUTION | PLATE | NEAR-SURFACE DAMAGE | Literature reviews | High aspect ratio | Patterning | Semiconductor devices
SELECTIVE SIO2 | CYCLOTRON-RESONANCE PLASMA | PHYSICS, APPLIED | POLYMER-FILM DEPOSITION | MECHANISM | REDUCTION | SILICON | HOLES | PROFILE EVOLUTION | PLATE | NEAR-SURFACE DAMAGE | Literature reviews | High aspect ratio | Patterning | Semiconductor devices
Journal Article
JAPANESE JOURNAL OF APPLIED PHYSICS, ISSN 0021-4922, 06/2019, Volume 58, Issue SE, p. SE0804
Semiconductor device production has grown year on year, with high-volume manufacturing supported by advances in plasma processes. In plasma-based processing,...
INITIAL OXIDATION PROCESSES | CYCLOTRON-RESONANCE PLASMA | PHYSICS, APPLIED | X-RAY PHOTOELECTRON | CHEMICAL-VAPOR-DEPOSITION | ELECTRON-IMPACT DISSOCIATION | ABSOLUTE DENSITY-MEASUREMENTS | LASER-INDUCED FLUORESCENCE | MOLECULAR-DYNAMICS SIMULATION | INDUCTIVELY-COUPLED PLASMA | CROSS-SECTION MEASUREMENTS | Literature reviews | Organic chemistry | Control methods | Computer simulation | Ion bombardment | Control equipment | Reaction kinetics | Chemical reactions | Intelligent processes | Product development
INITIAL OXIDATION PROCESSES | CYCLOTRON-RESONANCE PLASMA | PHYSICS, APPLIED | X-RAY PHOTOELECTRON | CHEMICAL-VAPOR-DEPOSITION | ELECTRON-IMPACT DISSOCIATION | ABSOLUTE DENSITY-MEASUREMENTS | LASER-INDUCED FLUORESCENCE | MOLECULAR-DYNAMICS SIMULATION | INDUCTIVELY-COUPLED PLASMA | CROSS-SECTION MEASUREMENTS | Literature reviews | Organic chemistry | Control methods | Computer simulation | Ion bombardment | Control equipment | Reaction kinetics | Chemical reactions | Intelligent processes | Product development
Journal Article
JAPANESE JOURNAL OF APPLIED PHYSICS, ISSN 0021-4922, 06/2019, Volume 58, Issue SE, p. SE0803
The non-thermal nature of chemical reactions in plasma chemistry is considered to be suitable for next-generation energy production from plasma-material...
ARGON PLASMA | LARGE-AREA | PHYSICS, APPLIED | CHEMICAL-VAPOR-DEPOSITION | COLD-PLASMA | AMORPHOUS-SILICON | SI FILMS | CRYSTALLIZATION TECHNIQUE | CHRONIC WOUNDS | DIELECTRIC-BARRIER-DISCHARGES | ATMOSPHERIC-PRESSURE PLASMA | Thin films | Literature reviews | Plasma | Organic chemistry | Atmospheric pressure | Chemical reactions | Multidisciplinary research | Plasmas | Plasma chemistry
ARGON PLASMA | LARGE-AREA | PHYSICS, APPLIED | CHEMICAL-VAPOR-DEPOSITION | COLD-PLASMA | AMORPHOUS-SILICON | SI FILMS | CRYSTALLIZATION TECHNIQUE | CHRONIC WOUNDS | DIELECTRIC-BARRIER-DISCHARGES | ATMOSPHERIC-PRESSURE PLASMA | Thin films | Literature reviews | Plasma | Organic chemistry | Atmospheric pressure | Chemical reactions | Multidisciplinary research | Plasmas | Plasma chemistry
Journal Article
International Journal of Urology, ISSN 0919-8172, 05/2012, Volume 19, Issue 5, pp. 388 - 401
Radical cystectomy plus urinary diversion, the reference standard treatment for muscle‐invasive bladder cancer, associates with high complication rates and...
chemoradiotherapy | partial cystectomy | muscle‐invasive bladder cancer | bladder preservation | Bladder preservation | Muscle-invasive bladder cancer | Chemoradiotherapy | Partial cystectomy | COMBINED-MODALITY THERAPY | HYPERFRACTIONATED RADIOTHERAPY | LOW-DOSE CHEMORADIOTHERAPY | LONG-TERM OUTCOMES | RADIATION-THERAPY | ORGAN PRESERVATION | muscle-invasive bladder cancer | RADICAL CYSTECTOMY | UROLOGY & NEPHROLOGY | QUALITY-OF-LIFE | PHASE-I | TRANSURETHRAL RESECTION | Cystectomy - mortality | Disease-Free Survival | Urinary Bladder Neoplasms - radiotherapy | Neoplasm Invasiveness | Humans | Survival Rate | Combined Modality Therapy | Urinary Bladder - pathology | Urinary Bladder Neoplasms - drug therapy | Urinary Bladder - surgery | Urinary Bladder Neoplasms - surgery | Cystectomy - methods
chemoradiotherapy | partial cystectomy | muscle‐invasive bladder cancer | bladder preservation | Bladder preservation | Muscle-invasive bladder cancer | Chemoradiotherapy | Partial cystectomy | COMBINED-MODALITY THERAPY | HYPERFRACTIONATED RADIOTHERAPY | LOW-DOSE CHEMORADIOTHERAPY | LONG-TERM OUTCOMES | RADIATION-THERAPY | ORGAN PRESERVATION | muscle-invasive bladder cancer | RADICAL CYSTECTOMY | UROLOGY & NEPHROLOGY | QUALITY-OF-LIFE | PHASE-I | TRANSURETHRAL RESECTION | Cystectomy - mortality | Disease-Free Survival | Urinary Bladder Neoplasms - radiotherapy | Neoplasm Invasiveness | Humans | Survival Rate | Combined Modality Therapy | Urinary Bladder - pathology | Urinary Bladder Neoplasms - drug therapy | Urinary Bladder - surgery | Urinary Bladder Neoplasms - surgery | Cystectomy - methods
Journal Article
Anticancer Research, ISSN 0250-7005, 03/2009, Volume 29, Issue 3, pp. 797 - 808
Heat-shock protein 90 (Hsp90) is a molecular chaperone required for the stability and function of numerous oncogenic signaling proteins that determine the...
Molecular chaperones | Molecularly targeted therapeutics | Geldanamycin | Metastasis | Review | Invasion | Cancer | Heat- Shock protein 90 | molecularly targeted therapeutics | BLADDER-CANCER | SOLID TUMORS | HEPATOCYTE GROWTH-FACTOR | ONCOGENIC TRANSFORMATION | FACTOR RECEPTOR | CELL LUNG-CANCER | HSP90 INHIBITORS | heat-shock protein 90 | invasion | ONCOLOGY | metastasis | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | PHASE-I TRIAL | review | geldanamycin | molecular chaperones | FOCAL ADHESION KINASE | Neoplasms - metabolism | Neoplasm Metastasis | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Neoplasm Invasiveness | Humans | HSP90 Heat-Shock Proteins - metabolism | Neoplasms - prevention & control | Clinical Trials as Topic | Neoplasms - pathology
Molecular chaperones | Molecularly targeted therapeutics | Geldanamycin | Metastasis | Review | Invasion | Cancer | Heat- Shock protein 90 | molecularly targeted therapeutics | BLADDER-CANCER | SOLID TUMORS | HEPATOCYTE GROWTH-FACTOR | ONCOGENIC TRANSFORMATION | FACTOR RECEPTOR | CELL LUNG-CANCER | HSP90 INHIBITORS | heat-shock protein 90 | invasion | ONCOLOGY | metastasis | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | PHASE-I TRIAL | review | geldanamycin | molecular chaperones | FOCAL ADHESION KINASE | Neoplasms - metabolism | Neoplasm Metastasis | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Neoplasm Invasiveness | Humans | HSP90 Heat-Shock Proteins - metabolism | Neoplasms - prevention & control | Clinical Trials as Topic | Neoplasms - pathology
Journal Article
Journal of Applied Physics, ISSN 0021-8979, 06/2019, Volume 125, Issue 21
The supply of reactive oxygen species (ROSs) into a tissue by plasmas must be controlled for the safe and effective use of plasma technologies in biomedical...
Plasma | Biomedical materials | Plasma jets | Reagents | Two dimensional models | Exposure | Plasmas
Plasma | Biomedical materials | Plasma jets | Reagents | Two dimensional models | Exposure | Plasmas
Journal Article
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Full Text
Acute Reperfusion Therapy and Stroke Care in Asia After Successful Endovascular Trials
Stroke, ISSN 0039-2499, 06/2015, Volume 46, Issue 6, pp. 1474 - 1481
The current status of and prospects for acute stroke care in Asia in the situation where both intravenous thrombolysis and endovascular therapies have been...
intracranial atherosclerosis | thrombolysis, therapeutic | Asia | thrombectomy | anticoagulants | cerebral hemorrhage | stroke | RISK-FACTORS | TISSUE-PLASMINOGEN ACTIVATOR | ARTERY OCCLUSION | FREE-RADICAL SCAVENGER | RANDOMIZED-TRIAL | CLINICAL NEUROLOGY | ATRIAL-FIBRILLATION | ALTEPLASE | SAFE IMPLEMENTATION | ACUTE ISCHEMIC-STROKE | PERIPHERAL VASCULAR DISEASE | 0.6 MG/KG | Life Style | Delivery of Health Care - organization & administration | Humans | Endovascular Procedures | Feeding Behavior | Clinical Trials as Topic | Tissue Plasminogen Activator - therapeutic use | Delivery of Health Care - standards | Thrombectomy | Reperfusion | Intracranial Hemorrhages - therapy | Fibrinolytic Agents - therapeutic use | Intracranial Arteriosclerosis - epidemiology | Intracranial Hemorrhages - epidemiology | Stroke - epidemiology | Far East | Intracranial Arteriosclerosis - therapy | Delivery of Health Care - trends | Stroke - therapy
intracranial atherosclerosis | thrombolysis, therapeutic | Asia | thrombectomy | anticoagulants | cerebral hemorrhage | stroke | RISK-FACTORS | TISSUE-PLASMINOGEN ACTIVATOR | ARTERY OCCLUSION | FREE-RADICAL SCAVENGER | RANDOMIZED-TRIAL | CLINICAL NEUROLOGY | ATRIAL-FIBRILLATION | ALTEPLASE | SAFE IMPLEMENTATION | ACUTE ISCHEMIC-STROKE | PERIPHERAL VASCULAR DISEASE | 0.6 MG/KG | Life Style | Delivery of Health Care - organization & administration | Humans | Endovascular Procedures | Feeding Behavior | Clinical Trials as Topic | Tissue Plasminogen Activator - therapeutic use | Delivery of Health Care - standards | Thrombectomy | Reperfusion | Intracranial Hemorrhages - therapy | Fibrinolytic Agents - therapeutic use | Intracranial Arteriosclerosis - epidemiology | Intracranial Hemorrhages - epidemiology | Stroke - epidemiology | Far East | Intracranial Arteriosclerosis - therapy | Delivery of Health Care - trends | Stroke - therapy
Journal Article
World Neurosurgery, ISSN 1878-8750, 10/2019, Volume 130, pp. e26 - e46
The epidemiology of patients with traumatic brain injury (TBI) has changed dramatically over recent decades as a result of rapid advances in aging societies....
Aging | Hospital mortality | Prognosis | Traumatic brain injury | Subdural hematoma | SURGERY | CARE | CLINICAL NEUROLOGY | IMPACT | CLINICAL-VARIABLES | HOSPITAL VOLUME | GENDER | COMA
Aging | Hospital mortality | Prognosis | Traumatic brain injury | Subdural hematoma | SURGERY | CARE | CLINICAL NEUROLOGY | IMPACT | CLINICAL-VARIABLES | HOSPITAL VOLUME | GENDER | COMA
Journal Article