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Diabetes Research and Clinical Practice, ISSN 0168-8227, 2016, Volume 120, pp. S25 - S26
Journal Article
Diabetes Research and Clinical Practice, ISSN 0168-8227, 10/2016, Volume 120, pp. S25 - S26
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 503, Issue 7477, pp. 493 - 499
Adiponectin secreted from adipocytes binds to adiponectin receptors AdipoR1 and AdipoR2, and exerts antidiabetic effects via activation of AMPK and PPAR-alpha... 
CRUCIAL ROLE | SKELETAL-MUSCLE | ACTIVATED PROTEIN-KINASE | FATTY-ACID OXIDATION | INSULIN-RESISTANCE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | DISEASE | MECHANISMS | ADIPONECTIN LEVELS | EXPRESSION | Liver - pathology | Obesity - drug therapy | Longevity - drug effects | Adipose Tissue, White - metabolism | Receptors, Adiponectin - metabolism | Diabetes Mellitus, Type 2 - metabolism | Muscle Fibers, Skeletal - drug effects | Obesity - genetics | Glucose Intolerance - drug therapy | Liver - drug effects | Piperidines - pharmacology | Inflammation - drug therapy | Adenylate Kinase - metabolism | Diet, High-Fat | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Receptors, Adiponectin - agonists | Adiponectin - metabolism | Drug Evaluation, Preclinical | Diabetes Mellitus, Type 2 - complications | Adipose Tissue, White - pathology | Adiponectin - pharmacology | Dyslipidemias - drug therapy | Piperidines - administration & dosage | Administration, Oral | Obesity - complications | Piperidines - metabolism | Liver - metabolism | Diabetes Mellitus, Type 2 - prevention & control | Insulin Resistance | Obesity - physiopathology | Transcription Factors - biosynthesis | Mitochondria - metabolism | Mitochondria - drug effects | Enzyme Activation - drug effects | Triglycerides - metabolism | Small Molecule Libraries - chemistry | Receptors, Adiponectin - deficiency | Animals | Signal Transduction - drug effects | Piperidines - therapeutic use | Muscle Fibers, Skeletal - cytology | Mice | Oxidative Stress - drug effects | PPAR alpha - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Adipose Tissue, White - drug effects | Receptors, Adiponectin - genetics | Muscles - cytology | Obesity | Insulin resistance | Muscular system | Kinases | Rodents
Journal Article
Nihon Naika Gakkai Zasshi, ISSN 0021-5384, 09/2017, Volume 106, Issue 9, pp. 1806 - 1810
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 04/2010, Volume 16, Issue 4, pp. 438 - 445
Class Ia phosphoinositide 3-kinase (PI3K), an essential mediator of the metabolic actions of insulin, is composed of a catalytic (p110 alpha or p110 beta) and... 
MEDICINE, RESEARCH & EXPERIMENTAL | METABOLIC SYNDROME | PHOSPHATIDYLINOSITOL 3-KINASE | ER STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOPLASMIC-RETICULUM STRESS | P85-ALPHA SUBUNIT | CELL BIOLOGY | SKELETAL-MUSCLE | MESSENGER-RNA | INSULIN-RESISTANCE | PURIFICATION METHOD | ADIPOSE-TISSUE | Insulin - physiology | Endoplasmic Reticulum - metabolism | Activating Transcription Factor 6 | Phosphatidylinositol 3-Kinases - metabolism | Cell Nucleus - physiology | X-Box Binding Protein 1 | Endoribonucleases - physiology | Gene Knockdown Techniques | Trans-Activators - physiology | DNA-Binding Proteins - metabolism | Cell Nucleus - metabolism | Membrane Proteins - physiology | Stress, Physiological - physiology | Cell Line | Unfolded Protein Response - drug effects | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Protein-Serine-Threonine Kinases - physiology | Liver - metabolism | Endoplasmic Reticulum - physiology | Regulatory Factor X Transcription Factors | Transcription Factors - metabolism | Animals | Tunicamycin - pharmacology | Liver - physiology | Phosphatidylinositol 3-Kinases - physiology | Mice | Apoptosis - physiology | Unfolded Protein Response - physiology | Transcription factors | Physiological aspects | Causes of | Insulin resistance | Genetic aspects | Research | Binding proteins | Protein kinases | Catalysis | Kinases | Metabolism | Protein folding | Insulin
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2006, Volume 281, Issue 36, pp. 26602 - 26614
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2004, Volume 101, Issue 28, pp. 10422 - 10427
Insulin resistance, obesity, diabetes, dyslipidemia, and nonalcoholic fatty liver are components of the metabolic syndrome, a disease complex that is... 
Obesity | Biological Sciences | Receptors | Cytokines | Liver | Antibodies | Insulin resistance | Mice | Type 2 diabetes mellitus | Diabetes | Insulin | TYROSINE KINASE-ACTIVITY | DIABETES-MELLITUS | OBESITY | INHIBITION | GENE | MULTIDISCIPLINARY SCIENCES | LIVER | SOCS-3 | NECROSIS-FACTOR-ALPHA | MICE | ADIPOSE-TISSUE | Phosphorylation | Suppressor of Cytokine Signaling 1 Protein | Male | Metabolic Syndrome - metabolism | Suppressor of Cytokine Signaling Proteins | DNA-Binding Proteins - metabolism | Mice, Mutant Strains | Metabolic Syndrome - physiopathology | Female | CCAAT-Enhancer-Binding Proteins - genetics | Repressor Proteins - metabolism | CCAAT-Enhancer-Binding Proteins - metabolism | Fatty Liver - metabolism | Down-Regulation | Fatty Liver - physiopathology | Liver - metabolism | Mice, Inbred C57BL | Insulin Resistance | Diabetes Mellitus - metabolism | Repressor Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Transcription Factors - metabolism | Carrier Proteins - genetics | Suppressor of Cytokine Signaling 3 Protein | Animals | Carrier Proteins - metabolism | Promoter Regions, Genetic - physiology | Diabetes Mellitus - physiopathology | Triglycerides - blood | Signal Transduction - physiology | Trans-Activators - metabolism | STAT3 Transcription Factor | Sterol Regulatory Element Binding Protein 1 | Metabolic regulation | Metabolic syndrome X | Research
Journal Article