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1. Full Text Expanding the spectrum of transthyretin amyloidosis
by Koike, Haruki and Katsuno, Masahisa
Muscle & Nerve, ISSN 0148-639X, 11/2019
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2. Zika Virus and Guillain-Barré Syndrome
by Koike, Haruki
Brain and nerve = Shinkei kenkyu no shinpo, ISSN 1881-6096, 02/2018, Volume 70, Issue 2, pp. 113 - 120
Journal Article
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3. Zika Virus and Guillain-Barré Syndrome
by Koike, Haruki
Brain and nerve = Shinkei kenkyu no shinpo, ISSN 1881-6096, 02/2018, Volume 70, Issue 2, p. 113
Recent studies revealed an association between Zika virus infection and a variety of neurological disorders, including microcephaly, meningoencephalitis,... 
Guillain-Barre Syndrome - therapy | Animals | Prognosis | Guillain-Barre Syndrome - diagnosis | Humans | Guillain-Barre Syndrome - etiology | Zika Virus | Zika Virus Infection - complications
Journal Article
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4. Non-systemic Vasculitic Neuropathy
by Koike, Haruki
Brain and nerve = Shinkei kenkyū no shinpo, ISSN 1881-6096, 03/2016, Volume 68, Issue 3, pp. 233 - 241
Journal Article
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5. Acute sensory neuropathies and acute autonomic neuropathies
by Koike, Haruki
Brain and Nerve, ISSN 1881-6096, 11/2015, Volume 67, Issue 11, pp. 1377 - 1387
Acute autonomic and sensory neuropathy | Acute sensory neuropathies | Guillain-Barre syndrome | Autoimmune autonomic ganglionopathy | Acute autonomic neuropathies
Journal Article
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6. Acute Sensory Neuropathies and Acute Autonomic Neuropathies
by Koike, Haruki
Brain and nerve = Shinkei kenkyu no shinpo, ISSN 1881-6096, 11/2015, Volume 67, Issue 11, p. 1377
From the perspective of neuropathies with an acute onset mimicking that of Guillain-Barré syndrome (GBS), cases with profound sensory and/or autonomic... 
Peripheral Nervous System Diseases - diagnosis | Acute Disease | Ganglia, Autonomic - ultrastructure | Humans | Autoimmune Diseases of the Nervous System - pathology | Autonomic Nervous System Diseases - diagnosis | Autonomic Nervous System - ultrastructure | Autoimmune Diseases of the Nervous System - immunology | Animals | Peripheral Nervous System Diseases - pathology | Autonomic Nervous System Diseases - pathology | Ganglia, Autonomic - immunology | Autoimmune Diseases of the Nervous System - diagnosis | Autonomic Nervous System Diseases - immunology
Journal Article
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7. Full Text New teased-fibre definitions represent specific mechanisms of neuropathy
by Koike, Haruki and Katsuno, Masahisa and Sobue, Gen
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 02/2019, Volume 90, Issue 2, pp. 124 - 124
Correspondence to Dr Haruki Koike, Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan;... 
neurofascin | amyloid | amyloidosis | pathology | polyglucosan body | lymphoma | biopsy | CIDP | neurolymphomatosis | SURGERY | POLYNEUROPATHY | PSYCHIATRY | CLINICAL NEUROLOGY | Morphology
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8. Full Text Clinicopathological features of neuropathy in anti-neutrophil cytoplasmic antibody-associated vasculitis
by Koike, Haruki and Sobue, Gen
Clinical and Experimental Nephrology, ISSN 1342-1751, 10/2013, Volume 17, Issue 5, pp. 683 - 685
Microscopic polyangiitis (MPA), Churg–Strauss syndrome (CSS), and Wegener’s granulomatosis are anti-neutrophil cytoplasmic antibody (ANCA)-associated... 
Nephrology | Microscopic polyangiitis | Vasculitis | Medicine & Public Health | Urology/Andrology | ANCA | Neuropathy | Churg–Strauss syndrome | Churg-Strauss syndrome | CHURG-STRAUSS-SYNDROME | UROLOGY & NEPHROLOGY | POLYANGIITIS-ASSOCIATED NEUROPATHY | Peripheral Nervous System Diseases - etiology | Churg-Strauss Syndrome - therapy | Humans | Biomarkers - analysis | Peripheral Nervous System Diseases - therapy | Churg-Strauss Syndrome - pathology | Treatment Outcome | Microscopic Polyangiitis - complications | Peripheral Nervous System - immunology | Peripheral Nervous System - pathology | Churg-Strauss Syndrome - complications | Microscopic Polyangiitis - therapy | Antibodies, Antineutrophil Cytoplasmic - analysis | Microscopic Polyangiitis - immunology | Peripheral Nervous System Diseases - pathology | Churg-Strauss Syndrome - immunology | Microscopic Polyangiitis - pathology | Peripheral Nervous System Diseases - immunology | Viral antibodies | Antibodies | Medical colleges
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9. Full Text The spectrum of immune-mediated autonomic neuropathies: insights from the clinicopathological features
by Koike, Haruki and Watanabe, Hirohisa and Sobue, Gen
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 01/2013, Volume 84, Issue 1, pp. 98 - 106
Although autonomic neuropathy may occur as a secondary consequence of various diseases, other patients without any obvious underlying diseases show profound... 
SURGERY | NERVOUS-SYSTEM | ACETYLCHOLINE-RECEPTOR ANTIBODY | ORTHOSTATIC TACHYCARDIA SYNDROME | PSYCHIATRY | GUILLAIN-BARRE-SYNDROME | ACUTE PANAUTONOMIC NEUROPATHY | SENSORY NEUROPATHY | GASTROINTESTINAL MOTOR DYSFUNCTION | CLINICAL NEUROLOGY | INTRAVENOUS IMMUNOGLOBULIN | SELECTIVE CHOLINERGIC DYSAUTONOMIA | ACUTE PANDYSAUTONOMIA | Autonomic Nervous System Diseases - complications | Humans | Sjogren's Syndrome - immunology | Paraneoplastic Syndromes - diagnosis | Sensation Disorders - immunology | Autonomic Nervous System Diseases - diagnosis | Autoimmune Diseases of the Nervous System - complications | Autoimmune Diseases of the Nervous System - immunology | Paraneoplastic Syndromes - complications | Sjogren's Syndrome - diagnosis | Receptors, Cholinergic - immunology | Paraneoplastic Syndromes - immunology | Sensation Disorders - diagnosis | Sjogren's Syndrome - complications | Autoantibodies - adverse effects | Autoimmune Diseases of the Nervous System - diagnosis | Autonomic Nervous System Diseases - immunology | Sensation Disorders - complications | Autonomic neuropathies | Immune response | Research | Index Medicus
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10. Full Text Hereditary transthyretin amyloidosis: a model of medical progress for a fatal disease
by Adams, David and Koike, Haruki and Slama, Michel and Coelho, Teresa
Nature Reviews Neurology, ISSN 1759-4758, 2019, Volume 15, Issue 7, pp. 387 - 404
Hereditary amyloidogenic transthyretin (ATTRv) amyloidosis with polyneuropathy (also known as familial amyloid polyneuropathy) is a condition with adult onset... 
SALIVARY-GLAND BIOPSY | LIVER-TRANSPLANTATION | WILD-TYPE TRANSTHYRETIN | FAMILIAL AMYLOIDOSIS | LONG-TERM SURVIVAL | PRACTICE PARAMETER EVALUATION | LATE-ONSET | SYMMETRIC POLYNEUROPATHY ROLE | PORTUGUESE PATIENTS | CLINICAL NEUROLOGY | APOLIPOPROTEIN-A-I
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11. Full Text Safety and efficacy of thalidomide in patients with POEMS syndrome: a multicentre, randomised, double-blind, placebo-controlled trial
by Misawa, Sonoko, MD and Sato, Yasunori, PhD and Katayama, Kanako, MSc and Nagashima, Kengo, PhD and Aoyagi, Reiko, BSc and Sekiguchi, Yukari, MD and Sobue, Gen, Prof and Koike, Haruki, MD and Yabe, Ichiro, MD and Sasaki, Hidenao, Prof and Watanabe, Osamu, MD and Takashima, Hiroshi, Prof and Nishizawa, Masatoyo, Prof and Kawachi, Izumi, MD and Kusunoki, Susumu, Prof and Mitsui, Yoshiyuki, MD and Kikuchi, Seiji, MD and Nakashima, Ichiro, MD and Ikeda, Shu-ichi, Prof and Kohara, Nobuo, MD and Kanda, Takashi, Prof and Kira, Jun-ichi, Prof and Hanaoka, Hideki, Prof and Kuwabara, Satoshi, Prof and Japanese POEMS Syndrome and Japanese POEMS Syndrome for Thalidomide (J-POST) Trial Study Group
Lancet Neurology, The, ISSN 1474-4422, 2016, Volume 15, Issue 11, pp. 1129 - 1137
Summary Background Polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes (POEMS) syndrome is a rare cause of demyelinating neuropathy, with... 
Neurology | PERIPHERAL NEUROPATHY | VEGF | CLINICAL NEUROLOGY | JAPAN | Thalidomide - adverse effects | Dexamethasone - administration & dosage | Double-Blind Method | Outcome Assessment (Health Care) | Anti-Inflammatory Agents - pharmacology | Humans | Middle Aged | Vascular Endothelial Growth Factor A - blood | Angiogenesis Inhibitors - pharmacology | Male | Thalidomide - administration & dosage | Thalidomide - pharmacology | POEMS Syndrome - drug therapy | Angiogenesis Inhibitors - administration & dosage | Dexamethasone - pharmacology | POEMS Syndrome - blood | Adult | Anti-Inflammatory Agents - administration & dosage | Female | Aged | Vascular Endothelial Growth Factor A - drug effects | Drug Therapy, Combination | Medical colleges | Neurosciences | Endothelial growth factors | Stem cells | Clinical trials | Transplantation | Skin | Research institutes | Proteins | Drug dosages | Blood | Multiple myeloma
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12. Full Text Diagnosis and management of transthyretin familial amyloid polyneuropathy in Japan: Red-flag symptom clusters and treatment algorithm
by Sekijima, Yoshiki and Ueda, Mitsuharu and Koike, Haruki and Misawa, Sonoko and Ishii, Tomonori and Ando, Yukio
Orphanet Journal of Rare Diseases, ISSN 1750-1172, 01/2018, Volume 13, Issue 1, pp. 6 - 17
Hereditary ATTR (ATTRm) amyloidosis (also called transthyretin-type familial amyloid polyneuropathy [ATTR-FAP]) is an autosomal-dominant, adult-onset, rare... 
Carpal tunnel syndrome | Amyloidosis neuropathy | Tafamidis | Red-flag symptom clusters | Cardiomyopathy | Hereditary ATTR amyloidosis | Disease-modifying agent | Familial amyloid polyneuropathy | Liver transplantation | MEDICINE, RESEARCH & EXPERIMENTAL | ATTR AMYLOIDOSIS | LIVER-TRANSPLANTATION | AUTONOMIC DYSFUNCTION | LONG-TERM SURVIVAL | CARPAL-TUNNEL-SYNDROME | AGE-OF-ONSET | VARIANT TRANSTHYRETIN | WORLD TRANSPLANT REGISTRY | BIOCHEMICAL FINDINGS | GENETICS & HEREDITY | CHOROID-PLEXUS | Care and treatment | Algorithms | Polyneuropathies | Gene mutations | Liver | Immunotherapy | Transplantation of organs, tissues, etc | Genetic aspects | Amyloidosis | Diagnosis | Health aspects | Donation of organs, tissues, etc
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13. Full Text Deciphering the mechanism and spectrum of chronic inflammatory demyelinating polyneuropathy using morphology
by Koike, Haruki and Katsuno, Masahisa and Sobue, Gen
Clinical and Experimental Neuroimmunology, ISSN 1759-1961, 02/2018, Volume 9, Issue 1, pp. 35 - 46
Chronic inflammatory demyelinating polyneuropathy (CIDP) is a form of chronic neuropathy characterized by demyelination due to immune‐mediated processes. In... 
chronic inflammatory demyelinating polyneuropathy | Schwann cell | node of Ranvier | neurofascin 155 | contactin 1 | Viral antibodies | Autoimmunity | Antibodies | Polyneuropathies
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14. Full Text Response criteria of tolvaptan for the treatment of hepatic edema
by Hiramine, Yasunari and Hiramine, Yasunari and Uojima, Haruki and Uojima, Haruki and Nakanishi, Hiroyuki and Nakanishi, Hiroyuki and Hiramatsu, Akira and Hiramatsu, Akira and Iwamoto, Takuya and Iwamoto, Takuya and Kimura, Mutsuumi and Kimura, Mutsuumi and Kawaratani, Hideto and Kawaratani, Hideto and Terai, Shuji and Terai, Shuji and Yoshiji, Hitoshi and Yoshiji, Hitoshi and Uto, Hirofumi and Uto, Hirofumi and Sakaida, Isao and Sakaida, Isao and Izumi, Namiki and Izumi, Namiki and Okita, Kiwamu and Okita, Kiwamu and Koike, Kazuhiko and Koike, Kazuhiko
Journal of Gastroenterology, ISSN 0944-1174, 2/2018, Volume 53, Issue 2, pp. 258 - 268
Although tolvaptan is an effective treatment for hepatic edema, there are no established criteria for assessment of the therapeutic effect. The present study... 
Tolvaptan | Medicine & Public Health | Colorectal Surgery | Hepatology | Gastroenterology | Abdominal Surgery | Hepatic edema | Body weight loss | Cutoff value | Surgical Oncology | Clinical findings | KIDNEY-DISEASE | MANAGEMENT | EFFICACY | PHARMACOLOGICAL ACTION | POST HOC ANALYSIS | HEPATORENAL-SYNDROME | REFRACTORY ASCITES | LIVER-CIRRHOSIS PATIENTS | DECOMPENSATED HEART-FAILURE | QUALITY-OF-LIFE | GASTROENTEROLOGY & HEPATOLOGY | Antidiuretic Hormone Receptor Antagonists - pharmacology | Tolvaptan - therapeutic use | Humans | Middle Aged | Male | Weight Loss - drug effects | Tolvaptan - administration & dosage | Dose-Response Relationship, Drug | Young Adult | Antidiuretic Hormone Receptor Antagonists - administration & dosage | Aged, 80 and over | Adult | Female | Retrospective Studies | Severity of Illness Index | Liver Cirrhosis - drug therapy | Reproducibility of Results | Tolvaptan - pharmacology | Treatment Outcome | Edema - drug therapy | Antidiuretic Hormone Receptor Antagonists - therapeutic use | ROC Curve | Aged | Edema - physiopathology | Liver Cirrhosis - physiopathology | Medical research | Dropsy | Edema | Care and treatment | Analysis | Body weight | Medicine, Experimental | Liver
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15. Full Text Ultrastructure in transthyretin amyloidosis: From pathophysiology to therapeutic insights
by Koike, Haruki and Katsuno, Masahisa
Biomedicines, ISSN 2227-9059, 03/2019, Volume 7, Issue 1, p. 11
Transthyretin (TTR) amyloidosis is caused by systemic deposition of wild-type or variant amyloidogenic TTR (ATTRwt and ATTRv, respectively). ATTRwt amyloidosis... 
Oligomers | Pathology | Therapy | Angiopathy | Tafamidis | Pathogenesis | Schwann cell | Protein misfolding disease | Diflunisal | Electron microscopy | angiopathy | pathogenesis | pathology | oligomers | therapy | diflunisal | electron microscopy | protein misfolding disease | tafamidis
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16. Full Text POLYGENETIC ABNORMALITIES IN JAPANESE PATIENTS WITH HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA
by Sekiguchi, Haruki and Koike, Toshiharu and Abe, Takuro and Sakai, Akiko and Sato, Kayoko and Hagiwara, Nobuhisa
Journal of the American College of Cardiology, ISSN 0735-1097, 03/2018, Volume 71, Issue 11, pp. A1756 - A1756
[...]its diagnosis rate in Japan is less than 1%. hFH is caused by mutations of FH genes such as LDL-receptor (LDLR), apolipoprotein B-100 (APOB), proprotein... 
Hypercholesterolemia | Mutation | Low density lipoprotein | Abnormalities
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17. Full Text Correction to: Diagnosis and management of transthyretin familial amyloid polyneuropathy in Japan: red-flag symptom clusters and treatment algorithm
by Sekijima, Yoshiki and Ueda, Mitsuharu and Koike, Haruki and Misawa, Sonoko and Ishii, Tomonori and Ando, Yukio
Orphanet journal of rare diseases, ISSN 1750-1172, 05/2019, Volume 14, Issue 1, pp. 111 - 1
Algorithms | Body mass index | Amyloid | Polyneuropathy | Transthyretin
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18. Full Text Paraneoplastic neuropathy
by Koike, Haruki and Sobue, Gen
2013, ISBN 9780444529022, Volume 115
Recent progress in serological screening of paraneoplastic antibodies and in diagnostic imaging techniques to detect malignancies has enabled a broadening of... 
chronic inflammatory demyelinating polyneuropathy | vasculitis | paraneoplastic neuropathy | sensory neuronopathy | neuropathy | Guillain–Barré syndrome | vasculitic neuropathy | autonomic neuropathy | chronic intestinal pseudo-obstruction | paraneoplastic syndrome | Chronic intestinal pseudo-obstruction | Vasculitis | Vasculitic neuropathy | Paraneoplastic syndrome | Neuropathy | Autonomic neuropathy | Paraneoplastic neuropathy | Sensory neuronopathy | Chronic inflammatory demyelinating polyneuropathy | Guillain-Barré syndrome | Paraneoplastic Polyneuropathy - therapy | Paraneoplastic Polyneuropathy - classification | Humans | Paraneoplastic Polyneuropathy - diagnosis
Book Chapter
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19. Full Text Paranodal dissection in chronic inflammatory demyelinating polyneuropathy with anti-neurofascin-155 and anti-contactin-1 antibodies
by Koike, Haruki and Kadoya, Masato and Kaida, Ken-ichi and Ikeda, Shohei and Kawagashira, Yuichi and Iijima, Masahiro and Kato, Daisuke and Ogata, Hidenori and Yamasaki, Ryo and Matsukawa, Noriyuki and Kira, Jun-ichi and Katsuno, Masahisa and Sobue, Gen
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 06/2017, Volume 88, Issue 6, pp. 465 - 473
ObjectiveTo investigate the morphological features of chronic inflammatory demyelinating polyneuropathy (CIDP) with autoantibodies directed against paranodal... 
AUTOANTIBODIES | SURGERY | PSYCHIATRY | NEUROFASCIN | IGG4 | CIDP | CLINICAL NEUROLOGY | PERIPHERAL-NERVE | DEFICIENCY NEUROPATHY | IVIG RESPONSIVENESS | POEMS SYNDROME | POLYRADICULONEUROPATHY | CLINICOPATHOLOGICAL FEATURES | Ranvier's Nodes - immunology | Neuroglia - pathology | Humans | Middle Aged | Male | Cell Adhesion Molecules - immunology | Schwann Cells - immunology | Young Adult | Polyradiculoneuropathy, Chronic Inflammatory Demyelinating - immunology | Sural Nerve - immunology | Sural Nerve - pathology | Neuroglia - immunology | Adult | Autoantibodies - analysis | Female | Polyradiculoneuropathy, Chronic Inflammatory Demyelinating - pathology | Myelin Sheath - immunology | Myelin Sheath - pathology | Schwann Cells - pathology | Nerve Growth Factors - immunology | Microscopy, Electron | Contactin 1 - immunology | Biopsy | Axons - pathology | Adolescent | Aged | Ranvier's Nodes - pathology | Axons - immunology | Viral antibodies | Complications and side effects | Usage | Guillain-Barre syndrome | Antibodies | Dosage and administration | Electron microscopy | Dissection | Risk factors
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