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Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1742, pp. 15 - 25
Journal Article
Journal Article
Nature, ISSN 0028-0836, 03/2012, Volume 483, Issue 7390, pp. 484 - 488
Journal Article
Trends in Molecular Medicine, ISSN 1471-4914, 12/2018, Volume 24, Issue 12, pp. 1021 - 1035
Journal Article
Nature Genetics, ISSN 1061-4036, 08/2014, Volume 46, Issue 9, pp. 951 - 956
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2007, Volume 282, Issue 7, pp. 4524 - 4532
The stability and transcriptional activity of the hypoxia-inducible factors (HIFs) are regulated by two oxygen-dependent events that are catalyzed by three HIF... 
Gene Expression Regulation, Enzymologic - drug effects | Transcription, Genetic - drug effects | Vascular Endothelial Growth Factor A - biosynthesis | Fibroblasts - enzymology | Fumarate Hydratase - chemistry | Mixed Function Oxygenases - metabolism | Fumarate Hydratase - deficiency | Mixed Function Oxygenases - chemistry | Succinate Dehydrogenase - chemistry | Procollagen-Proline Dioxygenase - metabolism | Dose-Response Relationship, Drug | Fumarate Hydratase - metabolism | Neoplasms - chemistry | Neoplasms - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Procollagen-Proline Dioxygenase - antagonists & inhibitors | Hypoxia-Inducible Factor 1, alpha Subunit - chemistry | Erythropoietin - biosynthesis | Fibroblasts - chemistry | Cell Line | Enzyme Inhibitors - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Citric Acid Cycle - drug effects | Neoplasms - enzymology | Mixed Function Oxygenases - antagonists & inhibitors | Fibroblasts - pathology | Succinate Dehydrogenase - deficiency | p300-CBP Transcription Factors - metabolism | Citric Acid Cycle - genetics | Procollagen-Proline Dioxygenase - genetics | Gene Expression Regulation, Enzymologic - genetics | Succinate Dehydrogenase - metabolism | Mixed Function Oxygenases - genetics | Neoplasms - pathology | Procollagen-Proline Dioxygenase - chemistry
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2003, Volume 278, Issue 33, pp. 30772 - 30780
Journal Article
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 13583 - 10
Hypoxia of residence at high altitude (> 2500 m) decreases birth weight. Lower birth weight associates with infant mortality and morbidity and increased... 
HIGH-ALTITUDE ADAPTATION | INDUCIBLE FACTOR | OBESITY | INHIBITION | MULTIDISCIPLINARY SCIENCES | FETAL-GROWTH | PROLYL 4-HYDROXYLASES | SELECTION | ANCESTRY | PREGNANCY | PROTECTS | Hypoxia-inducible factors | Adipose tissue | Glucagon | Fetuses | Glucose | Gestation | Metabolism | Insulin | Morbidity | Pregnancy | Glucose tolerance | Glucose metabolism | Glycolysis | Hypoxia | Birth weight | Lipid metabolism | Altitude
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 09/2018, Volume 430, Issue 18, pp. 3081 - 3092
Histone lysine demethylases (KDMs) are 2-oxoglutarate-dependent dioxygenases (2-OGDDs) that regulate gene expression by altering chromatin structure. Their... 
succinate | S-2HG | KDM | fumarate | R-2HG | TET ENZYMES | HYPOXIA-INDUCIBLE FACTOR | OXYGEN SENSING PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | METABOLISM | STRUCTURAL BASIS | DISEASE | PROLYL 4-HYDROXYLASES | SDH MUTATIONS | Enzymes | Methylation | Gene expression | Lysine | Cancer
Journal Article