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SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 3219 - 10
Comprehensive and accurate detection of variants from whole-genome sequencing (WGS) is a strong prerequisite for translational genomic medicine; however, low... 
BIOINFORMATICS PIPELINES | VARIANTS | SNP | ALIGNMENT | MULTIDISCIPLINARY SCIENCES | CANCER | DISCOVERY | TOOLS | Genomes | Gene frequency | Comparative analysis | Pipelines
Journal Article
Genetics in Medicine, ISSN 1098-3600, 12/2018, Volume 20, Issue 12, pp. 1617 - 1626
Purpose: To evaluate the coverage and accuracy of whole-exome sequencing (WES) across vendors. Methods: Blood samples from three trios underwent WES at three... 
depth of coverage | pharmacogenomics | breadth of coverage | false negatives | whole-exome sequencing | RECOMMENDATIONS | PERFORMANCE | GENES | GENETICS & HEREDITY | STANDARDS | CANCER | GENOME | whole exome sequencing
Journal Article
Oncotarget, ISSN 1949-2553, 02/2019, Volume 10, Issue 14, pp. 1399 - 1406
KLRG1 is a lymphocyte co-inhibitory, or immune checkpoint, receptor expressed predominantly on late-differentiated effector and effector memory CD8+ T and NK... 
Murine cancer models | Immunotherapy | Immune checkpoint receptor | Co-inhibitory receptor | KLRG1
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 04/2011, Volume 108, Issue 14, pp. 5632 - 5637
Identification of genomic regions that control tissue-specific gene expression is currently problematic. ChIP and high-throughput sequencing (ChIP-seq) of... 
Chromatin
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 04/2011, Volume 108, Issue 14, p. 5632
Identification of genomic regions that control tissue-specific gene expression is currently problematic. ChIP and high-throughput sequencing (ChIP-seq) of... 
Proteins | Heart | Tissue | Chromatin | Genomics | Genes | Epigenetics | Gene expression
Journal Article
BMC medical genomics, 09/2013, Volume 6, p. 34
Decades of research strongly suggest that the genetic etiology of autism spectrum disorders (ASDs) is heterogeneous. However, most published studies focus on... 
Reproducibility of Results | Child Development Disorders, Pervasive - genetics | Humans | Gene Expression Profiling | Genomics - methods | Case-Control Studies | Child Development Disorders, Pervasive - blood
Journal Article
Physiological Genomics, ISSN 1094-8341, 11/2007, Volume 31, Issue 3, pp. 367 - 373
MicroRNAs are recently discovered regulators of gene expression and are becoming increasingly recognized as important regulators of heart function. Genome-wide... 
Heart failure | Gene expression | Expression profiling | heart failure | PHYSIOLOGY | GENOMICS | expression profiling | MUSCLE-SPECIFIC MICRORNA | GENES | GENETICS & HEREDITY | IDENTIFICATION | CARDIOGENESIS | FAILURE | gene expression | CELL BIOLOGY | Analysis of Variance | Humans | Middle Aged | Female | Male | Aged | MicroRNAs - genetics | Case-Control Studies | Heart Diseases - genetics
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2005, Volume 102, Issue 38, pp. 13544 - 13549
Journal Article
Nature, ISSN 0028-0836, 10/2008, Volume 455, Issue 7216, pp. 1061 - 1068
Journal Article