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Nature Medicine, ISSN 1078-8956, 01/2013, Volume 19, Issue 1, pp. 83 - 92
Journal Article
FRONTIERS IN ENDOCRINOLOGY, ISSN 1664-2392, 09/2015, Volume 6, p. 154
Journal Article
INTERNATIONAL JOURNAL OF CANCER, ISSN 0020-7136, 07/2013, Volume 133, Issue 1, pp. 108 - 119
Maitake D (MD)-Fraction is a highly purified soluble -glucan derived from Grifola frondosa (an oriental edible mushroom). Intraperitoneal (i.p.) injection of... 
beta-glucan | DENDRITIC CELLS | MACROPHAGES | INNATE | RECEPTOR | INDUCTION | CANCER | oral administration | ONCOLOGY | dectin-1 | INFLAMMATION | PARTICULATE | Grifola frondosa | Lectins | Immune response | T cells | Immunotherapy | Tumors | Medical research | Chemotherapy | Rodents
Journal Article
Diabetologia, ISSN 0012-186X, 4/2015, Volume 58, Issue 4, pp. 809 - 818
Journal Article
PLOS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, p. e0176036
Bmps regulate numerous neural functions with their regulators. We previously identified Brorin, a neural-specific secreted antagonist of Bmp signaling, in... 
MOLECULAR MECHANISMS | RECEPTOR COMPLEXES | SONIC HEDGEHOG | MULTIDISCIPLINARY SCIENCES | NEURAL-TUBE | SPINAL-CORD | PROMOTES NEUROGENESIS | DORSAL TELENCEPHALON | EMBRYONIC ZEBRAFISH | CELL FATE | CEREBRAL-CORTEX | Immunohistochemistry | Bone Morphogenetic Proteins - antagonists & inhibitors | Oligodendroglia - metabolism | Embryo, Nonmammalian - metabolism | Neurogenesis | Bone Morphogenetic Proteins - metabolism | In Situ Hybridization | GABAergic Neurons - cytology | GABAergic Neurons - metabolism | Oligodendroglia - cytology | Prosencephalon - metabolism | Prosencephalon - growth & development | Astrocytes - cytology | Amino Acid Sequence | Nerve Tissue Proteins - antagonists & inhibitors | Signal Transduction | Zebrafish Proteins - metabolism | Zebrafish Proteins - antagonists & inhibitors | Nerve Tissue Proteins - genetics | Zebrafish - growth & development | Nerve Tissue Proteins - metabolism | Morpholinos - metabolism | Sequence Alignment | Animals | Zebrafish - metabolism | Axon Guidance | Mice | Zebrafish Proteins - genetics | Microscopy, Fluorescence | Astrocytes - metabolism | Physiological aspects | Embryonic development | Genetic aspects | Research | Nerve proteins | Cysteine | Regulators | Spinal cord | Interneurons | Genes | Forebrain | Amino acids | Biochemistry | Gliogenesis | Inactivation | γ-Aminobutyric acid | Rodents | Animal tissues | Oligodendrocytes | Bone morphogenetic proteins | Pharmaceutical sciences | Deactivation | Neurons | Astrocytes | Zebrafish | Chordin | Studies | Signaling | Insects | Axon guidance
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2017, Volume 12, Issue 3, p. e0173621
Maitake alpha-glucan, YM-2A, isolated from Grifola frondosa, has been characterized as a highly alpha-1,6-branched alpha-1,4 glucan. YM-2A has been shown to... 
SYSTEM | CELLS | ENZYMATICALLY SYNTHESIZED GLYCOGEN | MULTIDISCIPLINARY SCIENCES | NUCLEAR-MAGNETIC-RESONANCE | FRUIT BODY | GRIFOLA-FRONDOSA MAITAKE | COMBINATION | CANCER | MACROPHAGE ACTIVATION | POLYSACCHARIDE | Spleen - immunology | Colonic Neoplasms - drug therapy | Melanoma, Experimental - drug therapy | Spleen - drug effects | Antineoplastic Agents - administration & dosage | Glucans - administration & dosage | Pancreatic alpha-Amylases - metabolism | Melanoma, Experimental - immunology | Colonic Neoplasms - immunology | Female | Mice, Inbred DBA | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Macrophages - immunology | Cytokines - metabolism | Adjuvants, Immunologic | Administration, Oral | Mice, Inbred C57BL | Glucans - pharmacology | Macrophages - metabolism | Animals | Spleen - metabolism | Macrophages - drug effects | Mice | Mice, Inbred BALB C | Grifola - chemistry | Animal models | CD86 antigen | CD8 antigen | Liver | Viruses | Lymphocytes T | Glucose | Kinases | Macrophages | Experiments | Cancer therapies | Lymph nodes | Anticancer properties | Glucan | Lymphocytes | Immunotherapy | Bone marrow | Colon | Pancreas | Immune system | Spleen | CD11c antigen | CD11b antigen | Immune response | Cytokines | Ethanol | Dendritic cells | Amylopectin | Mushrooms | Research & development--R&D | Tumor cells | Glycogen | Melanoma | Patches (structures) | Pharmacology | Inflammation | Chemical compounds | CD4 antigen | Drainage | Chemistry | Major histocompatibility complex | Influenza | Antitumor activity | Peritoneum | Cancer | Pharmaceuticals | Research & development | R&D
Journal Article
Diabetes, ISSN 0012-1797, 05/2013, Volume 62, Issue 5, pp. 1453 - 1463
Glucagon, an essential regulator of glucose homeostasis, also modulates lipid metabolism and promotes weight loss, as reflected by the wasting observed in... 
PPAR-ALPHA | BODY-WEIGHT | METABOLISM | FIBROBLAST-GROWTH-FACTOR-21 | PHARMACOLOGY | INCREASES ENERGY-EXPENDITURE | ENDOCRINOLOGY & METABOLISM | DEGRADATION | MICE | INSULIN SENSITIVITY | FGF21 | Obesity - drug therapy | Humans | Peptides - pharmacokinetics | Fibroblast Growth Factors - genetics | Male | Fibroblast Growth Factors - secretion | Obesity - blood | Anti-Obesity Agents - therapeutic use | Glucagon - agonists | Fibroblast Growth Factors - metabolism | Anti-Obesity Agents - pharmacokinetics | Peptides - chemical synthesis | Hepatocytes - secretion | Hypoglycemic Agents - therapeutic use | Receptors, Glucagon - agonists | Receptors, Glucagon - genetics | Hypoglycemic Agents - pharmacokinetics | Peptides - physiology | Rats | Hypoglycemic Agents - pharmacology | Mice, Knockout | Cross-Over Studies | Anti-Obesity Agents - chemical synthesis | Mice | Anti-Obesity Agents - pharmacology | Hepatocytes - pathology | Diabetes Mellitus, Type 2 - metabolism | Hepatocytes - metabolism | Molecular Targeted Therapy | Mice, Mutant Strains | HEK293 Cells | Adult | Female | Hepatocytes - drug effects | Recombinant Proteins - metabolism | Double-Blind Method | Cells, Cultured | Insulin Resistance | Receptors, Glucagon - metabolism | Recombinant Proteins - agonists | Glucagon - pharmacology | Obesity - metabolism | Diabetes Mellitus, Type 2 - blood | Animals | Fibroblast Growth Factors - blood | Hypoglycemic Agents - chemical synthesis | Glucagon - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Peptides - therapeutic use | Physiological aspects | Fibroblast growth factors | Research | Glucagon | Analysis | Original Research
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2017, Volume 127, Issue 9, pp. 3496 - 3509
Journal Article
Journal Article
Journal of Nutrition and Metabolism, ISSN 2090-0724, 2011, Volume 2011, pp. 981315 - 8
The FGF family comprises twenty-two structurally related proteins with functions in development and metabolism. The Fgf21 gene was generated early in... 
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Journal Article