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1. Neurobiology of addiction
by Koob, George F and Le Moal, Michel
2006, ISBN 0124192394, viii, 490
Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms... 
Drug addiction | Neurobiology | Neuropharmacology | Family & Health
Book
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2. Eighth Annual Winter Neuropeptide Conference
: Breckenridge, CO, January 17-23, 1987
by Koob, George F
1988, 125-261.
Book
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3. Full Text Addiction and stress: An allostatic view
by Koob, George F and Schulkin, Jay
Neuroscience and Biobehavioral Reviews, ISSN 0149-7634, 11/2019, Volume 106, pp. 245 - 262
Allostasis, or stability through change, has most often been linked with challenges to homeostasis, in which repeated challenges or stressors produce... 
Corticotropin-releasing factor | Addiction | Glucocorticoids | Stress | Extended amygdala | Allostasis | Corticotropin releasing hormone | Drug abuse | Care and treatment | Neural circuitry | Corticosteroids | Analysis | ACTH | Substance abuse | Stress (Psychology)
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4. Larry Stein: pioneer neuropsychopharmacology researcher, mentor, and friend
by Koob, George F
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 09/2019
Journal Article
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5. Full Text Neurobiology of Opioid Addiction: Opponent Process, Hyperkatifeia, and Negative Reinforcement
by Koob, George F
Biological psychiatry, ISSN 0006-3223, 06/2019
Opioids are powerful drugs that usurp and overpower the reward function of endogenous opioids and engage dramatic tolerance and withdrawal via molecular and... 
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6. Theoretical frameworks and mechanistic aspects of alcohol addiction: alcohol addiction as a reward deficit disorder
by Koob, George F and Koob, George F
Current topics in behavioral neurosciences, ISSN 1866-3370, 2013, Volume 13, pp. 3 - 30
Alcoholism can be defined by a compulsion to seek and take drug, loss of control in limiting intake, and the emergence of a negative emotional state when... 
Opponent process | Corticotropin-releasing factor | Addiction | Extended amygdala | Stress | Brain - metabolism | Impulsive Behavior - etiology | Animals | Models, Biological | Humans | Alcoholism - complications | Reward | Corticotropin-Releasing Hormone - metabolism | Disease Models, Animal | Index Medicus
Journal Article
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7. Full Text Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats
by de Guglielmo, Giordano and Kallupi, Marsida and Pomrenze, Matthew B and Crawford, Elena and Simpson, Sierra and Schweitzer, Paul and Koob, George F and Messing, Robert O and George, Olivier
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1238 - 11
The activation of a neuronal ensemble in the central nucleus of the amygdala (CeA) during alcohol withdrawal has been hypothesized to induce high levels of... 
CORTICOTROPIN-RELEASING-FACTOR | NEUROTRANSMISSION | STRIA TERMINALIS | GABAERGIC TRANSMISSION | EXTENDED AMYGDALA | STRESS-INDUCED REINSTATEMENT | CENTRAL NUCLEUS | OPIOID SYSTEMS | MULTIDISCIPLINARY SCIENCES | ETHANOL WITHDRAWAL | BED NUCLEUS | Humans | Septal Nuclei - pathology | Male | Optogenetics | Septal Nuclei - cytology | Substance Withdrawal Syndrome - pathology | Behavior, Animal | Septal Nuclei - metabolism | Substance Withdrawal Syndrome - metabolism | Central Amygdaloid Nucleus - physiopathology | Corticotropin-Releasing Hormone - genetics | Neurons - metabolism | Neural Pathways - physiopathology | Septal Nuclei - physiopathology | Alcoholism - physiopathology | Behavior, Addictive - physiopathology | Disease Models, Animal | Alcoholism - pathology | Central Amygdaloid Nucleus - cytology | Rats | Corticotropin-Releasing Hormone - metabolism | Central Amygdaloid Nucleus - pathology | Animals | Neural Pathways - metabolism | Central Amygdaloid Nucleus - metabolism | Substance Withdrawal Syndrome - physiopathology | Substance Withdrawal Syndrome - psychology | Drug addiction | Deactivation | Amygdala | Neurons | Drinking behavior | Withdrawal | Stria terminalis | Alcohol | Inactivation | Corticotropin-releasing hormone | Alcohol use | Addiction | Inhibition
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8. DRUG ABUSE: HEDONIC HOMEOSTATIC DYSREGULATION
by KOOB, GEORGE F. & LE MOAL, MICHEL
Book
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9. Full Text The neurobiology of addiction
by Uhl, George R and Koob, George F and Cable, Jennifer
Annals of the New York Academy of Sciences, ISSN 0077-8923, 09/2019, Volume 1451, Issue 1, pp. 5 - 28
Substance and alcohol use disorders impose large health and economic burdens on individuals, families, communities, and society. Neither prevention nor... 
alcohol | nicotine | addiction | marijuana | substance abuse | neuroplasticity | opioids | COCAINE-SEEKING BEHAVIOR | USER PUFF TOPOGRAPHY | CUE-INDUCED REINSTATEMENT | MULTIDISCIPLINARY SCIENCES | ANXIETY-LIKE BEHAVIOR | CORTICOTROPIN-RELEASING-FACTOR | HIGH-SCHOOL-STUDENTS | N-ACETYL CYSTEINE | NUCLEUS-ACCUMBENS CORE | REDUCES ETHANOL-CONSUMPTION | NICOTINE METABOLITE RATIO | Marijuana | Substance abuse | Epidemics | Drug abuse | Drug addiction | Neurosciences | Alcohol | Nervous system | Addictions | Cigarettes | Cigarette smoking | Substance use | Cannabis | Recreational use | Addiction | Opioids | Drug use
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10. Full Text Periaqueductal Gray Sheds Light on Dark Areas of Psychopathology
by George, DT and Ameli, R and Koob, GF
TRENDS IN NEUROSCIENCES, ISSN 0166-2236, 05/2019, Volume 42, Issue 5, pp. 349 - 360
Neurons in the periaqueductal gray (PAG) integrate negative emotions with the autonomic, neuroendocrine, and immune systems to facilitate responses to threat.... 
PREDICTION ERRORS | PANIC DISORDER | DEPRESSION-LIKE BEHAVIOR | CENTRAL NUCLEUS | AMINO-ACID MICROINJECTION | OPIOID RECEPTORS | NEURAL MECHANISMS | SEX-DIFFERENCES | SELECT GROUP | NEUROSCIENCES | PREFRONTAL CORTEX
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11. Full Text The dark side of emotion: The addiction perspective
by Koob, George F
European Journal of Pharmacology, ISSN 0014-2999, 04/2015, Volume 753, pp. 73 - 87
Emotions are “feeling” states and classic physiological emotive responses that are interpreted based on the history of the organism and the context. Motivation... 
Opponent process | Corticotropin-releasing factor | Incentive salience | Extended amygdala | Dynorphin | Allostasis | WITHDRAWAL-INDUCED ANXIETY | BRAIN REWARD FUNCTION | KAPPA-OPIOID RECEPTOR | AMINOBUTYRIC-ACID RELEASE | Allo stasis | ANXIETY-LIKE BEHAVIOR | INTRACRANIAL SELF-STIMULATION | ETHANOL-DEPENDENT RATS | PREFERRING P-RATS | CORTICOTROPIN-RELEASING-FACTOR | PHARMACOLOGY & PHARMACY | PITUITARY-ADRENAL AXIS | Brain - metabolism | Substance-Related Disorders - metabolism | Animals | Motivation | Humans | Neurotransmitter Agents - metabolism | Reward | Emotions | Neuropeptide Y | Corticotropin releasing hormone | ACTH | Neural circuitry | Alcoholism | corticotropin-releasing factor | dynorphin | emotion | opponent process | incentive salience | allostasis | extended amygdala
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12. Full Text Refractory dependence on opioid analgesics
by Ballantyne, Jane C and Sullivan, Mark D and Koob, George F
Pain, ISSN 0304-3959, 08/2019, p. 1
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13. Full Text A Role for Brain Stress Systems in Addiction
by Koob, George F
Neuron, ISSN 0896-6273, 2008, Volume 59, Issue 1, pp. 11 - 34
Drug addiction is a chronically relapsing disorder characterized by compulsion to seek and take drugs and has been linked to dysregulation of brain regions... 
NEUROPEPTIDE-Y NPY | ETHANOL-DEPENDENT RATS | IN-VIVO MICRODIALYSIS | PRECIPITATED MORPHINE-WITHDRAWAL | CORTICOTROPIN-RELEASING-FACTOR | COCAINE-SEEKING BEHAVIOR | CONDITIONED PLACE PREFERENCE | KAPPA-OPIOID RECEPTOR | ANXIETY-LIKE BEHAVIOR | NEUROSCIENCES | HYPOTHALAMIC PARAVENTRICULAR NUCLEUS | Brain - pathology | Stress, Physiological - pathology | Substance-Related Disorders - pathology | Animals | Brain - physiopathology | Humans | Neurotransmitters | Impulsivity | Dopamine | Anxieties | Rodents | Alcoholism | Neuropeptides | Addictions | Nicotine | Index Medicus
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