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1. Full Text A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies
by Lehne, Benjamin and Drong, Alexander W and Loh, Marie and Zhang, Weihua and Scott, William R and Tan, Sian-Tsung and Afzal, Uzma and Scott, James and Jarvelin, Marjo-Riitta and Elliott, Paul and McCarthy, Mark I and Kooner, Jaspal S and Chambers, John C
Genome Biology, ISSN 1474-7596, 02/2015, Volume 16, Issue 1, pp. 37 - 37
Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Epigenomics - methods | Oligonucleotide Array Sequence Analysis | Epigenesis, Genetic - genetics | Humans | CpG Islands - genetics | DNA Methylation - genetics | Software | Genome, Human | Genome-Wide Association Study - methods | Quantitative Trait Loci - genetics | Quantitative trait loci | Studies | Quality control | DNA methylation | Epigenetics | Genomes | Chromosomes | Index Medicus | Method
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2. Full Text Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease
by Meurs, Joyce and Paré, Guillaume and Schwartz, Stephen and Hazra, Aditi and Tanaka, T and Vermeulen, Sita and Cotlarciuc, Ioana and Yuan, Xin and Mälarstig, Anders and Bandinelli, Stefania and Bis, Joshua and Blom, Henk and Brown, Morris and Chen, Christopher and Clarke, Robert and Dehghan, Abbas and Erdmann, Jeanette and Ferrucci, L and Hamsten, Anders and Hofman, Albert and Hunter, David and Goel, Anuj and Johnson, Anew and Kathiresan, Sekar and Kampman, Ellen and Kiel, Douglas and Kiemeney, Bart and Chambers, John and Kraft, Peter and Lindemans, Jan and McKnight, Barbara and Nelson, Christopher P and O'Donnell, Christopher and Psaty, Bruce and Ridker, Paul and Rivadeneira Ramirez, Fernando and Rose, Lynda and Seedorf, Udo and Siscovick, David and Schunkert, Heribert and Selhub, Jacob and Ueland, Per and Vollenweider, Peter and Waeber, Gérard and Waterworth, Dawn and Watkins, Hugh and Witteman, Jacqueline and Heijer, Martin and Jacques, Paul and Uitterlinden, Ané and Kooner, Jaspal and Rader, Daniel and Reilly, Muredach and Mooser, Vincent and Chasman, Daniel and Samani, Nilesh and Ahmadi, Kourosh
The American journal of clinical nutrition, ISSN 0002-9165, 09/2013, Volume 98, Issue 3, pp. 668 - 676
coronary artery disease | hyperhomocysteinemia | cohort analysis | gene | meta analysis | single nucleotide polymorphism | major clinical study | aged | genetic association | article | genetic variability | genotype | gene locus | controlled study | adolescent | adult | female | human | male | Life Sciences & Biomedicine | Nutrition & Dietetics | Science & Technology | Fundamental and applied biological sciences. Psychology | Feeding. Feeding behavior | Cardiology. Vascular system | Heart | Vertebrates: anatomy and physiology, studies on body, several organs or systems | Biological and medical sciences | Medical sciences | Coronary heart disease | Genetic Predisposition to Disease | Coronary Artery Disease - etiology | Genes | Humans | Risk Factors | Coronary Artery Disease - genetics | Homocysteine - blood | Genotype | Genetic Loci | Coronary Artery Disease - blood | Homocysteine - genetics | Polymorphism, Genetic | Genetic aspects | Homocysteine | Health aspects | Risk factors | Genetic polymorphisms | Cardiovascular disease | Genomes | Gene loci | Meta-analysis | Index Medicus | Abridged Index Medicus | Clinical trials | Kardiologi | Medicinsk genetik | Klinisk medicin | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | heart-disease | metaanalysis | expression | identification | polymorphism | genome-wide association | cardiovascular-disease | mthfr | mendelian randomization | women
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3. Full Text Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial
by Al-Lamee, Rasha and Thompson, David and Dehbi, Hakim-Moulay and Sen, Sayan and Tang, Kare and Davies, John and Keeble, Thomas and Mielewczik, Michael and Kaprielian, Raffi and Malik, Iqbal S and Nijjer, Sukhjinder S and Petraco, Ricardo and Cook, Christopher and Ahmad, Yousif and Howard, James and Baker, Christopher and Sharp, Andrew and Gerber, Robert and Talwar, Suneel and Assomull, Ravi and Mayet, Jamil and Wensel, Roland and Collier, David and Shun-Shin, Matthew and Thom, Simon A and Davies, Justin E and Francis, Darrel P and Al-Lamee, Rasha and Thompson, David and Sen, Sayan and Tang, Kare and Davies, John and Keeble, Thomas and Kaprielian, Raffi and Malik, Iqbal S and Nijjer, Sukhjinder S and Petraco, Ricardo and Cook, Christopher and Ahmad, Yousif and Howard, James and Shun-Shin, Matthew and Sethi, Amarjit and Baker, Christopher and Sharp, Andrew and Ramrakha, Punit and Gerber, Robert and Talwar, Suneel and Assomull, Ravi and Foale, Rodney and Mayet, Jamil and Wensel, Roland and Thom, Simon A and Davies, Justin E and Francis, Darrel P and Khamis, Ramzi and Hadjiloizou, Nearchos and Khan, Masood and Kooner, Jaspal and Bellamy, Michael and Mikhail, Ghada and Clifford, Piers and O'Kane, Peter and Levy, Terry and Swallow, Rosie and ORBITA investigators and ORBITA Investigators
The Lancet (British edition), ISSN 0140-6736, 01/2018, Volume 391, Issue 10115, pp. 31 - 40
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Coronary Stenosis - diagnostic imaging | Coronary Stenosis - complications | Double-Blind Method | Humans | Middle Aged | Male | Treatment Outcome | United Kingdom | Angina, Stable - surgery | Coronary Angiography | Coronary Stenosis - surgery | Exercise Tolerance | Angina, Stable - complications | Female | Aged | Angina, Stable - diagnostic imaging | Percutaneous Coronary Intervention | Transluminal angioplasty | Clinical trials | Angina pectoris | Analysis | Hypertension | Angioplasty | Coronary artery | Cardiovascular disease | Systematic review | Angina | Evidence-based medicine | Quality of life | Studies | Medical prognosis | Coronary vessels | Cardiology | Index Medicus | Abridged Index Medicus
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4. Full Text Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile
by Kilpeläinen, Tuomas and Zillikens, Carola and Stancáková, Alena and Finucane, Francis and Ried, Janina and Langenberg, Claudia and Zhang, Weihua and Beckmann, Jacques and Luan, J and Vandenput, Liesbeth and Styrkarsdottir, Unnur and Zhou, Yanhua and Smith, Albert Vernon and Zhao, Jing Hua and Amin, Najaf and Vedantam, Sailaja and Shin, S.-Y and Haritunians, Talin and Fu, Mao and Feitosa, Mary Furlan and Kumari, Meena and Halldorsson, Bjarni and Tikkanen, Emmi and Mangino, Massimo and Hayward, Caroline and Song, Ci and Arnold, Alice and Oostra, Ben and Campbell, Harry and Cupples, Aienne and Davis, Kathryn and Döring, Angela and Eiriksdottir, Gudny and Estrada Gil, Karol and Fernández-Real, J.M and Garcia, Melissa and Gieger, Christian and Glazer, Nicole and Guiducci, Candace and Hofman, Albert and Humphries, Steve and Isomaa, Bo and Jacobs, Leonie and Jula, Antti and Karasik, David and Karlsson, Magnus and Khaw, Kay-Tee and Kim, Lauren and Kivimaki, Mika and Klopp, Norman and Kuhnel, Brigitte and Kuusisto, Johanna and Liu, YongMei and Ljunggren, Ö and Lorentzon, Mattias and Luben, Robert and McKnight, Barbara and Mellström, Dan and Mitchell, Braxton and Mooser, Vincent and Moreno, J.M and Männistö, Satu and O'Connell, Jeffery and Pascoe, Laura and Peltonen, Leena Johanna and Peral, Belén and Perola, Markus and Psaty, Bruce and Salomaa, Veikko and Savage, David and Semple, Robert and Skaric-Juric, Tatjana and Sigurdsson, Gunnar and Spector, Timothy and Syvänen, A.-C and Talmud, Philippa and Thorleifsson, Gudmar and Thorsteinsdottir, Unnur and Uitterlinden, Ané and Tikka-Kleemola, Päivi and Vidal-Puig, Antonio and Wild, Sarah and Wright, Alan and Clegg, Deborah and Schadt, Eric and Wilson, James and Rudan, Igor and Ripatti, Samuli and Borecki, Ingrid and Shuldiner, Alan and Ingelsson, Erik and Jansson, J.O and Kaplan, Robert and Gudnason, Vilmundur and Harris, Tamara and Groop, Leif and Kiel, Douglas and Rivadeneira Ramirez, Fernando and Walker, Mark and Barroso, Inês and ... and Göteborgs universitet and Institutionen för medicin, avdelningen för invärtesmedicin and Gothenburg University and Institute of Neuroscience and Physiology, Department of Physiology and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi and Institute of Medicine, Department of Internal Medicine
Nature genetics, ISSN 1061-4036, 08/2011, Volume 43, Issue 8, pp. 753 - 760
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Body Mass Index | Genome-Wide Association Study | Meta-Analysis as Topic | Body Weight | Humans | Male | Adiposity - genetics | Obesity - genetics | Metabolome - genetics | Adiponectin - blood | Membrane Proteins | Alleles | Subcutaneous Fat | Polymorphism, Single Nucleotide - genetics | Female | Genetic Variation - genetics | Body Fat Distribution | Insulin Receptor Substrate Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Body mass index | Usage | Receptors | Genetic variation | Physiological aspects | Insulin resistance | Genetic aspects | Research | Insulin | Medical research | Biomedical research | Body fat | Research & development--R&D | Genomes | Meta-analysis | Mens health | Weight control | Hospitals | Womens health | Metabolic disorders | Index Medicus | MEDICIN OCH HÄLSOVETENSKAP | Endokrinologi och diabetes | MEDICAL AND HEALTH SCIENCES | Endocrinology and Diabetes
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5. Full Text Association analyses based on false discovery rate implicate new loci for coronary artery disease
by Nelson, Christopher P and Goel, Anuj and Butterworth, Adam S and Kanoni, Stavroula and Webb, Tom R and Marouli, Eirini and Zeng, Lingyao and Ntalla, Ioanna and Lai, Florence Y and Hopewell, Jemma C and Giannakopoulou, Olga and Jiang, Tao and Hamby, Stephen E and Di Angelantonio, Emanuele and Assimes, Themistocles L and Bottinger, Erwin P and Chambers, John C and Clarke, Robert and Palmer, Colin N A and Cubbon, Richard M and Ellinor, Patrick and Ermel, Raili and Evangelou, Evangelos and Franks, Paul W and Grace, Christopher and Gu, Dongfeng and Hingorani, Aroon D and Howson, Joanna M M and Ingelsson, Erik and Kastrati, Adnan and Kessler, Thorsten and Kyriakou, Theodosios and Lehtimäki, Terho and Lu, Xiangfeng and Lu, Yingchang and März, Winfried and McPherson, Ruth and Metspalu, Andres and Pujades-Rodriguez, Mar and Ruusalepp, Arno and Schadt, Eric E and Schmidt, Amand F and Sweeting, Michael J and Zalloua, Pierre A and Alghalayini, Kamal and Keavney, Bernard D and Kooner, Jaspal S and Loos, Ruth J F and Patel, Riyaz S and Rutter, Martin K and Tomaszewski, Maciej and Tzoulaki, Ioanna and Zeggini, Eleftheria and Erdmann, Jeanette and Dedoussis, George and Björkegren, Johan L M and Schunkert, Heribert and Farrall, Martin and Danesh, John and Samani, Nilesh J and Watkins, Hugh and Deloukas, Panos and Uk Biobank CardioMetab and EPIC-CVD Consortium and CardiogramplusC4D and UK Biobank CardioMetabolic Consortium CHD working group and CARDIoGRAMplusC4D and The UK Biobank CardioMetabolic Consortium CHD working group
Nature genetics, ISSN 1061-4036, 09/2017, Volume 49, Issue 9, pp. 1385 - 1391
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Association Studies - standards | Health Information Systems - statistics & numerical data | Genetic Predisposition to Disease - genetics | Meta-Analysis as Topic | Reproducibility of Results | Humans | Risk Factors | Genetic Loci - genetics | Genetic Association Studies - methods | Genotype | United Kingdom | Genome-Wide Association Study - statistics & numerical data | Phenotype | Genetic Association Studies - statistics & numerical data | Coronary Artery Disease - genetics | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Genome-Wide Association Study - standards | Health Information Systems - standards | Genetic aspects | Disease susceptibility | Research | Coronary heart disease | Risk factors | Coronary artery | Cardiovascular disease | Genomes | Angina | Gene expression | Metabolism | Angina pectoris | Coronary artery disease | Loci | Meta-analysis | Morphogenesis | Studies | Consortia | Nitric oxide | Coronary vessels | Atherosclerosis | Heritability | Lipid metabolism | Bioinformatics | Heart diseases | Index Medicus | Kardiologi | Medicinsk genetik | Basic Medicine | Medical Genetics | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin
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6. Full Text Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity
by Wahl, Simone and ng, A and Lehne, B and Loh, M and Scott, William R and Kunze, S and Tsai, P.-C and Ried, J.S and Zhang, Weihua and Yang, Y and Tan, S and Fiorito, G and Franke, Lude and Guarrera, Simonetta and Kasela, Silva and Kriebel, Jennifer and Richmond, Rebecca C and Adamo, M and Afzal, Uzma and Ala-Korpela, Mika and Albetti, B and Ammerpohl, Ole and Apperley, Jane and Beekman, Marian and Bertazzi, P.A and Black, S.L and Blancher, Christine and Bonder, Marc and Brosch, M and Carstensen-Kirberg, M and Craen, Anton and Lusignan, Simon and Dehghan, Abbas and Elkalaawy, M and Fischer, Krista and Franco, Oscar and Gaunt, Tom and Hampe, Jochen and Hashemi, M and Isaacs, Aaron and Jenkinson, A and Jha, S and Kato, Norihiro and Krogh, V and Laffan, M and Meisinger, Christa and Meitinger, T and Mok, Zuan Yu and Motta, V and Ng, H.K and Nikolakopoulou, Z and Nteliopoulos, G and Panico, S and Pervjakova, Natalia and Prokisch, Holger and Rathmann, Wolfgang and Roden, Michael and Rota, F and Rozario, Michelle Ann and Sandling, Johanna and Schafmayer, Clemens and Schramm, Katharina and Siebert, Reiner and Slagboom, Eline and Soininen, Pasi and Stolk, Lisette and Strauch, K and Tai, Shyong and Tarantini, L and Thorand, Barbara and Tigchelaar, Ettje F and Tumino, Rosario and Uitterlinden, Ané and Duijn, Cornelia and Meurs, Joyce and Vineis, Paolo and Wickremasinghe, Ananda and Wijmenga, C and Yang, Tsun-Po and Yuan, W and Zhernakova, Alexana and Batterham, R.L and Smith, Davey and Deloukas, P and Heijmans, B.T and Herder, Christian and Hofman, Albert and Lindgren, Cecilia M and Milani, Lili and Harst, Pim and Peters, Annette and Illig, T and Relton, Caroline and Waldenberger, M and Jarvelin, Marjo-Riitta and Bollati, V and Soong, R and Spector, Timothy and Scott, J and McCarthy, Mark and ...
Nature (London), ISSN 0028-0836, 01/2017, Volume 541, Issue 7635, pp. 81 - 86
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Overweight - complications | Diabetes Mellitus, Type 2 - genetics | Epigenesis, Genetic | Humans | Asian Continental Ancestry Group - genetics | India - ethnology | Male | Blood - metabolism | Obesity - blood | Obesity - genetics | Europe - ethnology | Adipose Tissue - metabolism | Female | Diabetes Mellitus, Type 2 - complications | Body Mass Index | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Epigenomics | Obesity - complications | Overweight - genetics | DNA Methylation - genetics | Genetic Markers | Adiposity - genetics | Overweight - blood | Cohort Studies | Epigenetic inheritance | Body mass index | Obesity | Genome-wide association studies | Genetic aspects | Health aspects | Neutrophils | Cardiovascular disease | Metabolism | Gene expression | Asthma | Studies | DNA methylation | Epigenetics | Population | Gene loci | Diabetes | Deoxyribonucleic acid--DNA | Asians | Index Medicus
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7. Full Text A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease
by Nikpay, Majid and Goel, Anuj and Won, Hong-Hee and Hall, Leanne M and Willenborg, Christina and Kanoni, Stavroula and Saleheen, Danish and Kyriakou, Theodosios and Nelson, Christopher P and CHopewell, Jemma and Webb, Thomas R and Zeng, Lingyao and Dehghan, Abbas and Alver, Maris and MArmasu, Sebastian and Auro, Kirsi and Bjonnes, Andrew and Chasman, Daniel I and Chen, Shufeng and Ford, Ian and Franceschini, Nora and Gieger, Christian and Grace, Christopher and Gustafsson, Stefan and Huang, Jie and Hwang, Shih-Jen and Kim, Yun Kyoung and Kleber, Marcus E and Lau, King Wai and Lu, Xiangfeng and Lu, Yingchang and Lyytikäinen, Leo-Pekka and Mihailov, Evelin and Morrison, Alanna C and Pervjakova, Natalia and Qu, Liming and Rose, Lynda M and Salfati, Elias and Saxena, Richa and Scholz, Markus and Smith, Albert V and Tikkanen, Emmi and Uitterlinden, Andre and Yang, Xueli and Zhang, Weihua and Zhao, Wei and De Andrade, Mariza and De Vries, Paul S and Van Zuydam, Natalie R and Anand, Sonia S and Bertram, Lars and Beutner, Frank and Dedoussis, George and Frossard, Philippe and Gauguier, Dominique and Goodall, Alison H and Gottesman, Omri and Haber, Marc and Han, Bok-Ghee and Huang, Jianfeng and Jalilzadeh, Shapour and Kessler, Thorsten and König, Inke R and Lannfelt, Lars and Lieb, Wolfgang and Lind, Lars and MLindgren, Cecilia and Lokki, Marja-Liisa and Magnusson, Patrik K and Mallick, Nadeem H and Mehra, Narinder and Meitinger, Thomas and Memon, Fazal-Uur-Rehman and Morris, Andrew P and Nieminen, Markku S and Pedersen, Nancy L and Peters, Annette and Rallidis, Loukianos S and Rasheed, Asif and Samuel, Maria and Shah, Svati H and Sinisalo, Juha and EStirrups, Kathleen and Trompet, Stella and Wang, Laiyuan and Zaman, Khan S and Ardissino, Diego and Boerwinkle, Eric and Borecki, Ingrid B and Bottinger, Erwin P and Buring, Julie E and Chambers, John C and Collins, Rory and Cupples, Ladrienne and Danesh, John and Demuth, Ilja and Elosua, Roberto and Epstein, Stephen E and Esko, Tõnu and Feitosa, Mary F and ... and CARDIoGRAMplusC4D Consortium and the CARDIoGRAMplusC4D Consortium
Nature genetics, ISSN 1061-4036, 09/2015, Volume 47, Issue 10, pp. 1121 - 1130
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic susceptibility | Genetic research | Development and progression | Genetic aspects | Single nucleotide polymorphisms | Research | Cardiovascular research | Coronary heart disease | Health aspects | Kardiologi | Medicinsk genetik | Basic Medicine | Medical Genetics | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin
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