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science & technology (380) 380
life sciences & biomedicine (343) 343
humans (271) 271
urology & nephrology (169) 169
male (149) 149
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female (130) 130
biological and medical sciences (122) 122
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young adult (30) 30
focal segmental glomerulosclerosis (29) 29
genetic predisposition to disease (28) 28
glomerulosclerosis, focal segmental - genetics (28) 28
kidney - pathology (28) 28
apol1 (26) 26
cells, cultured (26) 26
fibrosis (26) 26
podocytes - metabolism (26) 26
research article (26) 26
rodents (26) 26
child (25) 25
nephropathies. renovascular diseases. renal failure (25) 25
proteinuria (25) 25
african americans (24) 24
physiology (24) 24
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health aspects (20) 20
immunology (20) 20
aids/hiv (19) 19
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glomerulosclerosis, focal segmental - pathology (19) 19
incidence (19) 19
kidney transplantation (19) 19
medicine, general & internal (19) 19
disease progression (18) 18
pathology (18) 18
time factors (18) 18
apolipoprotein l1 - genetics (17) 17
hiv infections - complications (17) 17
molecular motor proteins - genetics (17) 17
myosin heavy chains - genetics (17) 17
polymorphism, single nucleotide (17) 17
renal failure (17) 17
development and progression (16) 16
hiv-1 - genetics (16) 16
kidney - metabolism (16) 16
medical research (16) 16
medicine (16) 16
mice, inbred c57bl (16) 16
mice, knockout (16) 16
podocytes - pathology (16) 16
prospective studies (16) 16
rats (16) 16
signal transduction (16) 16
urinary system involvement in other diseases. miscellaneous (16) 16
urogenital system (16) 16
aids-associated nephropathy - genetics (15) 15
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1. Full Text Phase II trial of the glycoprotein non-metastatic B-targeted antibody–drug conjugate, glembatumumab vedotin (CDX-011), in recurrent osteosarcoma AOST1521: A report from the Children's Oncology Group
by Kopp, Lisa M and Malempati, Suman and Krailo, Mark and Gao, Yun and Buxton, Allen and Weigel, Brenda J and Hawthorne, Thomas and Crowley, Elizabeth and Moscow, Jeffrey A and Reid, Joel M and Villalobos, Victor and Randall, R. Lor and Gorlick, Richard and Janeway, Katherine A
European journal of cancer (1990), ISSN 0959-8049, 11/2019, Volume 121, pp. 177 - 183
Molecular targeted therapy | Clinical trial | Osteosarcoma | Paediatrics | Adolescent | Young adult | Life Sciences & Biomedicine | Oncology | Science & Technology | Immunohistochemistry | Analysis | Clinical trials | Monoclonal antibodies | Product development | Metastasis | Biopharmaceutics | Conjugates | Toxicity | Immunoglobulin G | Glycoproteins | Disease control | Metastases | Anticancer properties | Bone cancer | Biomedical materials | Children | Solid tumors | Pharmacokinetics | Adolescents | Tumors | Index Medicus
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2. Full Text Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice
by Beckerman, Pazit and Bi-Karchin, Jing and Park, Ae Seo Deok and Qiu, Chengxiang and Dummer, Patrick D and Soomro, Irfana and Boustany-Kari, Carine M and Pullen, Steven S and Miner, Jeffrey H and Hu, Chien-An A and Rohacs, Tibor and Inoue, Kazunori and Ishibe, Shuta and Saleem, Moin A and Palmer, Matthew B and Cuervo, Ana Maria and Kopp, Jeffrey B and Susztak, Katalin
Nature medicine, ISSN 1078-8956, 04/2017, Volume 23, Issue 4, pp. 429 - 438
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Immunohistochemistry | Lipoproteins, HDL - genetics | Glomerulosclerosis, Focal Segmental - genetics | Humans | Endosomes - metabolism | Genetic Variation | Kidney Glomerulus - ultrastructure | Apolipoproteins - genetics | HEK293 Cells | Renal Insufficiency, Chronic - genetics | Kidney Glomerulus - metabolism | Endocytosis - genetics | Autophagy - genetics | In Situ Nick-End Labeling | Genetic Predisposition to Disease | Podocytes - metabolism | Azotemia - genetics | Mice, Transgenic | Kidney Glomerulus - pathology | Microscopy, Electron | Blotting, Western | Renal Insufficiency, Chronic - pathology | Albuminuria - genetics | Podocytes - ultrastructure | Animals | Alleles | Apolipoprotein L1 | Fluorescent Antibody Technique | Mice | HeLa Cells | Glomerulosclerosis, Focal Segmental - pathology | Genetic aspects | Kidney diseases | Apolipoproteins | Gene expression | Health aspects | Risk factors | Index Medicus | albuminuria | pyroptosis | glomerulosclerosis | APOL1 | podocytes
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3. Full Text MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis
by Ahuja, Tejinder S and Berns, Jeffrey S and Nelson, George W and Kimmel, Paul L and Winkler, Cheryl A and Johnson, Randall C and Freedman, Barry I and Kajiyama, Hiroshi and Vlahov, David and Trachtman, Howard and Smith, Michael W and McKenzie, Louise M and Cho, Monique E and Dart, Richard A and Briggs, William and Kopp, Jeffrey B and Korbet, Stephen M and Bowden, Donald W and Michel, Donna M and Mokrzycki, Michele H and Simon, Eric and Oleksyk, Taras and Schelling, Jeffrey R
Nature genetics, ISSN 1061-4036, 10/2008, Volume 40, Issue 10, pp. 1175 - 1184
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Glomerulonephritis | Nephropathies. Renovascular diseases. Renal failure | Nephrology. Urinary tract diseases | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease - genetics | Glomerulosclerosis, Focal Segmental - genetics | Humans | Middle Aged | Risk Factors | African Americans - genetics | Myosin Heavy Chains - genetics | Male | Chromosome Mapping | DNA Primers - chemistry | Molecular Motor Proteins - genetics | Case-Control Studies | Lod Score | AIDS-Associated Nephropathy - genetics | Chromosomes, Human, Pair 22 - genetics | Haplotypes - genetics | Polymorphism, Single Nucleotide - genetics | Adult | Female | Hypertension - genetics | Genome, Human | Glomerulosclerosis, Focal Segmental - pathology | Genetic Linkage | Chromosome mapping | Demographic aspects | Genetic variation | African Americans | Genetic aspects | Research | Health aspects | Methods | Risk factors | Medical research | Genetics | Genes | Cancer | Index Medicus
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4. Full Text Living near major roads and the incidence of dementia, Parkinson's disease, and multiple sclerosis: a population-based cohort study
by Chen, Hong, PhD and Kwong, Jeffrey C, MD and Copes, Ray, MD and Tu, Karen, MD and Villeneuve, Paul J, PhD and van Donkelaar, Aaron, PhD and Hystad, Perry, PhD and Martin, Randall V, Prof and Murray, Brian J, MD and Jessiman, Barry, MSc and Wilton, Andrew S, MSc and Kopp, Alexander, BA and Burnett, Richard T, PhD
The Lancet (British edition), ISSN 0140-6736, 2017, Volume 389, Issue 10070, pp. 718 - 726
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Residence Characteristics | Urban Population - statistics & numerical data | Humans | Middle Aged | Proportional Hazards Models | Male | Motor Vehicles | Dementia - epidemiology | Multiple Sclerosis - epidemiology | Incidence | Young Adult | Ontario - epidemiology | Parkinson Disease - epidemiology | Adult | Female | Aged | Cohort Studies | Medicine, Experimental | Medical research | Analysis | Public health | Dementia | Brain | Injuries | Outdoor air quality | Multiple sclerosis | Roads & highways | Parkinsons disease | Air pollution | Health risk assessment | Pollutants | Alzheimers disease | Index Medicus | Abridged Index Medicus
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5. Full Text Global glomerulosclerosis in primary nephrotic syndrome: including age as a variable to predict renal outcomes
by Kopp, Jeffrey B
Kidney international, ISSN 0085-2538, 05/2018, Volume 93, Issue 5, pp. 1043 - 1044
Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Pathology | Kidneys | Biopsy | Arteriosclerosis | Cell cycle | Aging | Nephrotic syndrome | Diabetes | Kidney diseases | Age | Index Medicus
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6. Full Text De novo expression of podocyte proteins in parietal epithelial cells during experimental glomerular disease
by Takamoto Ohse and Michael R. Vaughan and Jeffrey B. Kopp and Ronald D. Krofft and Caroline B. Marshall and Alice M. Chang and Kelly L. Hudkins and Charles E. Alpers and Jeffrey W. Pippin and Stuart J. Shankland
American Journal of Physiology - Renal Physiology, ISSN 1931-857X, 03/2010, Volume 298, Issue 3, pp. 702 - 711
Glomerulonephritis | FSGS | Phenotype | Membranous nephropathy | Differentiation | Physiology | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Immunohistochemistry | Cell Proliferation | Epithelial Cells - metabolism | Transforming Growth Factor beta1 - metabolism | Antibodies | Male | Anti-Glomerular Basement Membrane Disease - metabolism | Glomerulonephritis - metabolism | Doxorubicin | Glomerulonephritis, Membranous - metabolism | Heymann Nephritis Antigenic Complex - immunology | Anti-Glomerular Basement Membrane Disease - immunology | Time Factors | Glomerulonephritis, Membranous - immunology | Glomerulosclerosis, Focal Segmental - chemically induced | Biomarkers - metabolism | Autoantibodies | Podocytes - metabolism | Anti-Glomerular Basement Membrane Disease - pathology | Glomerulonephritis, Membranous - pathology | Glomerulonephritis - genetics | Rats | Epithelial Cells - pathology | Mice, Transgenic | Transforming Growth Factor beta1 - genetics | Podocytes - pathology | Rats, Sprague-Dawley | Glomerulosclerosis, Focal Segmental - metabolism | Animals | Proteins - metabolism | Glomerulonephritis - pathology | Mice | Mice, Inbred BALB C | Glomerulosclerosis, Focal Segmental - pathology | Cellular proteins | Epithelial cells | Physiological aspects | Parietal cells | Development and progression | Genetic aspects | Cell differentiation | Gene expression | Properties | Proteins | Membranes | Kidney diseases | Urogenital system | Cells | Index Medicus | phenotype | differentiation | glomerulonephritis | membranous nephropathy
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7. Full Text Expanding the spectrum of APOL1-related renal disease: de novo collapsing glomerulopathy following kidney transplant
by Kopp, Jeffrey B
Kidney international, ISSN 0085-2538, 12/2018, Volume 94, Issue 6, pp. 1048 - 1050
Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Index Medicus
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8. Full Text APOL1 Risk Variants, Race, and Progression of Chronic Kidney Disease
by Parsa, Afshin and Kao, W.H. Linda and Xie, Dawei and Astor, Brad C and Li, Man and Hsu, Chi-yuan and Feldman, Harold I and Parekh, Rulan S and Kusek, John W and Greene, Tom H and Fink, Jeffrey C and Anderson, Amanda H and Choi, Michael J and Wright, Jackson T and Lash, James P and Freedman, Barry I and Ojo, Akinlolu and Winkler, Cheryl A and Raj, Dominic S and Kopp, Jeffrey B and He, Jiang and Jensvold, Nancy G and Tao, Kaixiang and Lipkowitz, Michael S and Appel, Lawrence J and AASK Study Investigators and CRIC Study Investigators
The New England journal of medicine, ISSN 0028-4793, 12/2013, Volume 369, Issue 23, pp. 2183 - 2196
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | General aspects | Kidneys | Urinary system involvement in other diseases. Miscellaneous | Nephropathies. Renovascular diseases. Renal failure | Renal failure | Nephrology. Urinary tract diseases | Biological and medical sciences | Medical sciences | Multivariate Analysis | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Glomerular Filtration Rate | Lipoproteins, HDL - genetics | Humans | Middle Aged | African Americans - genetics | Male | Kidney Failure, Chronic - ethnology | Disease Progression | Kidney Failure, Chronic - genetics | Renal Insufficiency, Chronic - ethnology | Apolipoproteins - genetics | Apolipoprotein L1 | Renal Insufficiency, Chronic - genetics | Creatinine - blood | Hypertension - complications | Adult | Female | Aged | Diabetes Complications - genetics | Polymorphism, Single Nucleotide | Proteinuria | Demographic aspects | Genetic variation | African Americans | Genetic aspects | Research | Kidney diseases | Apolipoproteins | Health aspects | Risk factors | Hypertension | Creatinine | End-stage renal disease | Epidermal growth factor receptors | Risk groups | Medical treatment | Diabetes mellitus | Glomerular filtration rate | Renal insufficiency | Diabetes | Index Medicus | Abridged Index Medicus
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9. Full Text Chronic Kidney Disease in the Aging Human Immunodeficiency Virus–Infected Population
by Kopp, Jeffrey B
The Journal of infectious diseases, ISSN 0022-1899, 09/2017, Volume 216, Issue 6, pp. 619 - 621
HIV-associated nephropathy | End-stage kidney disease | Albuminuria | Chronic inflammation | Estimated glomerular filtration rate | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | HIV Infections | Renal Insufficiency, Chronic | Prevalence | HIV | Humans | Middle Aged | Disease Progression | Index Medicus | Abridged Index Medicus | Editor's Choice
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10. Full Text CD2-Associated Protein Haploinsufficiency Is Linked to Glomerular Disease Susceptibility
by Jeong M. Kim and Hui Wu and Gopa Green and Cheryl A. Winkler and Jeffrey B. Kopp and Jeffrey H. Miner and Emil R. Unanue and Andrey S. Shaw
Science (American Association for the Advancement of Science), ISSN 0036-8075, 5/2003, Volume 300, Issue 5623, pp. 1298 - 1300
Endocytosis | Kidneys | Focal segmental glomerulosclerosis | Exons | B lymphocytes | Reports | Mice | Kidney diseases | Ferritins | Kidney cortex | Proteinuria | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Glomerulonephritis | Nephrology. Urinary tract diseases | Biological and medical sciences | Medical sciences | Nephropathies. Renovascular diseases. Renal failure | Cytoskeletal Proteins | Antigen-Antibody Complex | Glomerulosclerosis, Focal Segmental - genetics | Humans | Chromatography, High Pressure Liquid | Basement Membrane - pathology | Kidney Diseases - genetics | Genetic Variation | Epithelial Cells - physiology | RNA Splicing | Ferritins - metabolism | Polymerase Chain Reaction | Kidney Glomerulus - metabolism | Kidney Diseases - metabolism | Proteinuria - etiology | Proteins - physiology | Genetic Predisposition to Disease | Kidney Diseases - pathology | Epithelial Cells - pathology | Immunoglobulins - analysis | Kidney Glomerulus - pathology | Basement Membrane - metabolism | Glomerulosclerosis, Focal Segmental - metabolism | Mice, Knockout | Polymorphism, Genetic | Basement Membrane - immunology | Proteins - genetics | Adaptor Proteins, Signal Transducing | Glomerular Mesangium - pathology | Animals | Glomerular Mesangium - immunology | Heterozygote | Kidney Glomerulus - immunology | Mutation | Glomerulosclerosis, Focal Segmental - pathology | Genetic aspects | Research | Proteins | Disease | Index Medicus
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11. Full Text Rethinking hypertensive kidney disease: Arterionephrosclerosis as a genetic, metabolic, and inflammatory disorder
by Kopp, Jeffrey B
Current opinion in nephrology and hypertension, ISSN 1062-4821, 05/2013, Volume 22, Issue 3, pp. 266 - 272
Apolipoprotein L1 | Arterionephrosclerosis | Hypertensive kidney disease | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Urology & Nephrology | Science & Technology | Lipoproteins, HDL - genetics | Prognosis | Oxidative Stress | Renal Insufficiency, Chronic - etiology | Nephritis - genetics | Humans | Hypertension, Renal - metabolism | Hypertension, Renal - immunology | Genetic Variation | Renal Insufficiency, Chronic - metabolism | Nephritis - immunology | Apolipoproteins - genetics | Inflammation Mediators - metabolism | Renal Insufficiency, Chronic - genetics | Hypertension, Renal - ethnology | Genetic Predisposition to Disease | Renal Insufficiency, Chronic - immunology | Comorbidity | Risk Factors | Hypertension, Renal - etiology | Nephritis - etiology | Continental Population Groups - genetics | Disease Progression | Nephritis - ethnology | Phenotype | Animals | Energy Metabolism | Renal Insufficiency, Chronic - ethnology | Ne