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1. Diabetes bei Kindern und Jugendlichen
: Grundlagen - Klinik - Therapie
by Danne, Thomas and Kordonouri, Olga and Lange, Karin and SpringerLink (Online service)
2015, 7., vollst. überarb. Aufl. 2015., ISBN 9783642246456
Wegweiser zur pädiatrischen Diabetologie aus einem Guss Eine gute ärztliche Begleitung durch den pädiatrischen Diabetologen ist entscheidend für die Prognose... 
Medicine | Pediatrics | Internal medicine | Family medicine | Diabetes
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2. Full Text Nocturnal Glucose Control with an Artificial Pancreas at a Diabetes Camp
by Phillip, Moshe and Battelino, Tadej and Atlas, Eran and Kordonouri, Olga and Bratina, Natasa and Miller, Shahar and Biester, Torben and Avbelj Stefanija, Magdalena and Muller, Ido and Nimri, Revital and Danne, Thomas
The New England Journal of Medicine, ISSN 0028-4793, 02/2013, Volume 368, Issue 9, pp. 824 - 833
This randomized, crossover trial compared an artificial-pancreas system with a sensor-augmented pump for nocturnal glucose control in young persons with type 1... 
SYSTEM | VARIABILITY | MEDICINE, GENERAL & INTERNAL | INTENSIVE TREATMENT | MANAGEMENT | ADOLESCENTS | HYPOGLYCEMIA | MELLITUS | YOUNG-CHILDREN | INSULIN-PUMP THERAPY | ACCURACY | Glycated Hemoglobin A - analysis | Hypoglycemic Agents - therapeutic use | Pancreas, Artificial - adverse effects | Humans | Insulin Infusion Systems - adverse effects | Blood Glucose | Male | Diabetes Mellitus, Type 1 - therapy | Cross-Over Studies | Hypoglycemia - prevention & control | Diabetes Mellitus, Type 1 - blood | Adolescent | Female | Hypoglycemia - chemically induced | Camping | Child | Hypoglycemic Agents - adverse effects | Insulin - adverse effects | Insulin - therapeutic use | Carbohydrates | Automation | Diabetes mellitus | Diabetes mellitus (insulin dependent) | Calibration | Glucose | Hypoglycemia | Insulin | Patients | Studies | Control algorithms | Software | Diabetes | Sensors | Pancreas | Meals | Index Medicus | Abridged Index Medicus
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3. Full Text MD-logic overnight control for 6 weeks of home use in patients with type 1 diabetes: Randomized crossover trial
by Nimri, Revital and Muller, Ido and Atlas, Eran and Miller, Shahar and Fogel, Aviel and Bratina, Natasa and Kordonouri, Olga and Battelino, Tadej and Danne, Thomas and Phillip, Moshe
Diabetes Care, ISSN 0149-5992, 11/2014, Volume 37, Issue 11, pp. 3025 - 3032
OBJECTIVE We evaluated the effect of the MD-Logic system on overnight glycemic control at patients' homes. RESEARCH DESIGN AND METHODS Twenty-four patients... 
SYSTEM | ARTIFICIAL PANCREAS | GLUCOSE CONTROL | FEASIBILITY | ADOLESCENTS | ENDOCRINOLOGY & METABOLISM | ADULTS | HYPOGLYCEMIA | AUGMENTED PUMP THERAPY | LOOP INSULIN DELIVERY | CHILDREN | Hypoglycemic Agents - therapeutic use | Hypoglycemia - epidemiology | Humans | Insulin - administration & dosage | Male | Hyperglycemia - drug therapy | Diabetes Mellitus, Type 1 - drug therapy | Blood Glucose - drug effects | Cross-Over Studies | Young Adult | Hypoglycemic Agents - administration & dosage | Adolescent | Adult | Female | Insulin Infusion Systems | Hyperglycemia - epidemiology | Child | Insulin - therapeutic use | Clinical trials | Therapy | Diabetes | Glucose | Closed loop systems | Biosensors | Index Medicus
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4. Full Text Association of Insulin Pump Therapy vs Insulin Injection Therapy With Severe Hypoglycemia, Ketoacidosis, and Glycemic Control Among Children, Adolescents, and Young Adults With Type 1 Diabetes
by Karges, Beate and Schwandt, Anke and Heidtmann, Bettina and Kordonouri, Olga and Binder, Elisabeth and Schierloh, Ulrike and Boettcher, Claudia and Kapellen, Thomas and Rosenbauer, Joachim and Holl, Reinhard W
JAMA, ISSN 0098-7484, 10/2017, Volume 318, Issue 14, pp. 1358 - 1366
IMPORTANCE: Insulin pump therapy may improve metabolic control in young patients with type 1 diabetes, but the association with short-term diabetes... 
DPV DATABASE | MEDICINE, GENERAL & INTERNAL | GERMANY | MANAGEMENT | INFUSION | EDUCATION | METABOLIC-CONTROL | AUSTRIA | Glycated Hemoglobin A - analysis | Blood Glucose - analysis | Humans | Child, Preschool | Insulin Infusion Systems - adverse effects | Infant | Insulin - administration & dosage | Male | Diabetes Mellitus, Type 1 - drug therapy | Young Adult | Regression Analysis | Injections | Hypoglycemic Agents - administration & dosage | Diabetes Mellitus, Type 1 - blood | Adolescent | Female | Hypoglycemia - chemically induced | Child | Hypoglycemic Agents - adverse effects | Insulin - adverse effects | Cohort Studies | Diabetic Ketoacidosis - chemically induced | Care and treatment | Type 1 diabetes | Analysis | Insulin pumps | Glycemic index | Research | Hypoglycemia | Comparative analysis | Adolescence | Therapy | Young adults | Complications | Migration | Diabetes mellitus | Population studies | Injection | Insulin | Patients | Risk factors | Body mass index | Weighting | Body mass | Body size | Ketoacidosis | Hemoglobin | Adults | Diabetes | Children | Adolescents | Index Medicus | Abridged Index Medicus | Original Investigation
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5. Full Text Beyond type 2 diabetes: sodium glucose co‐transporter‐inhibition in type 1 diabetes
by Biester, Torben and Kordonouri, Olga and Danne, Thomas
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 04/2019, Volume 21, Issue S2, pp. 53 - 61
Use of sodium glucose cotransporter (SGLT) inhibitors are a well‐established therapeutic option in type 2 diabetes (T2D) with a variety of proven therapeutic... 
ketone | diabetic ketoacidosis | insulin | β‐hydroxybutyrate | SGLT | DKA | type‐1 diabetes | YOUNG-ADULTS | GLYCEMIC CONTROL | SEVERE HYPOGLYCEMIA | SGLT2 INHIBITORS | INSULIN SUSPENSION | COTRANSPORTER 2 INHIBITION | ENDOCRINOLOGY & METABOLISM | DOUBLE-BLIND | CARDIOVASCULAR-DISEASE | beta-hydroxybutyrate | BETA-HYDROXYBUTYRATE LEVELS | PUMP THERAPY | type-1 diabetes | Type 2 diabetes | Type 1 diabetes | Glucose | Children | Health aspects | Drug approval | Dextrose | Glucose transporter | Cardiovascular system | Ketogenesis | Diabetes mellitus | Clinical trials | Population studies | Diabetes mellitus (insulin dependent) | Insulin | Patients | Regulatory approval | Sodium | Risk assessment | Ketoacidosis | Diabetes | Cardiovascular diseases | Diabetes mellitus (non-insulin dependent)
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6. Full Text Combined SGLT1 and SGLT2 Inhibitors and Their Role in Diabetes Care
by Danne, Thomas and Biester, Torben and Kordonouri, Olga
Diabetes Technology & Therapeutics, ISSN 1520-9156, 06/2018, Volume 20, Issue S2, pp. S2-69 - S2-77
The sodium–glucose cotransporter type 1 (SGLT1) is the primary transporter for absorption of glucose and galactose in the gastrointestinal tract. Inhibition... 
Original Articles | DKA prevention | Children | Type 1 diabetes | SGLT2 inhibitor | SGLT1 inhibitor | GLYCEMIC CONTROL | DAPAGLIFLOZIN | LX4211 | COTRANSPORTER 2 INHIBITION | SOTAGLIFLOZIN | INSULIN | GLUCOSE-HOMEOSTASIS | ENDOCRINOLOGY & METABOLISM | DOUBLE-BLIND | DUAL SGLT1/SGLT2 INHIBITOR | TYPE-1 | Hypoglycemic Agents - therapeutic use | Sodium-Glucose Transporter 1 - antagonists & inhibitors | Humans | Diabetes Mellitus, Type 2 - drug therapy | Glycosides - therapeutic use | Sodium-Glucose Transporter 2 - antagonists & inhibitors | Diabetes Mellitus, Type 1 - drug therapy | Insulin | Glucose | Diabetes | Index Medicus
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7. Full Text Pädiatrie – Motor der technologischen Weiterentwicklung in der Diabetologie
by Biester, Torben and Kordonouri, Olga
Der Diabetologe, ISSN 1860-9716, 7/2019, Volume 15, Issue 5, pp. 408 - 415
In der Pädiatrie finden die stetigen Weiterentwicklungen der Diabetestechnologien sowohl in der klinischen Erprobung als auch der therapeutischen Anwendung... 
Jugendliche | Selbstkontrolle des Blutzuckerspiegels | Metabolic Diseases | Diabetes mellitus, type 1 | General Practice / Family Medicine | Internal Medicine | Blood glucose self-monitoring | Angiology | Typ-1-Diabetes | Medicine & Public Health | Kinder | Adolescent | Diabetes | Insulininfusionssysteme | Child | Endocrinology | Insulin infusion systems | Diabetes mellitus
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8. Full Text "let the Algorithm Do the Work": Reduction of Hypoglycemia Using Sensor-Augmented Pump Therapy with Predictive Insulin Suspension (SmartGuard) in Pediatric Type 1 Diabetes Patients
by Biester, Torben and Kordonouri, Olga and Holder, Martin and Remus, Kerstin and Kieninger-Baum, Dorothee and Wadien, Tanja and Danne, Thomas
Diabetes Technology and Therapeutics, ISSN 1520-9156, 03/2017, Volume 19, Issue 3, pp. 173 - 182
A sensor-augmented insulin pump (SAP) using the MiniMed 640G system with SmartGuard™ technology allows an automatic stop of insulin delivery based on... 
Sensor-augmented pump therapy (SAP) | Continuous glucose monitoring (CGM) | Hypoglycemia prevention | Hypoglycemia suspension | Hypoglycemic Agents - therapeutic use | Blood Glucose - analysis | Humans | Insulin - administration & dosage | Male | Diabetes Mellitus, Type 1 - drug therapy | Hypoglycemia - prevention & control | Algorithms | Hypoglycemic Agents - administration & dosage | Diabetes Mellitus, Type 1 - blood | Adolescent | Female | Insulin Infusion Systems | Hypoglycemia - blood | Hypoglycemia - chemically induced | Child | Hypoglycemic Agents - adverse effects | Insulin - adverse effects | Insulin - therapeutic use | Usage | Care and treatment | Hypoglycemia | Type 1 diabetes | Risk factors | Insulin pumps | Pediatrics | Glucose | Sensors | Diabetes | Insulin | Index Medicus
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9. Full Text Transatlantic differences in the management of T2DM in youth
by Danne, Thomas and Kordonouri, Olga
Nature reviews. Endocrinology, ISSN 1759-5029, 05/2013, Volume 9, Issue 5, pp. 263 - 264
If a child has diabetic keotacidosis and the type of diabetes mellitus is unclear, immediately start them on insulin. This recommendation is one of a number... 
Diabetes Mellitus, Type 2 - drug therapy | United States | Child | Europe | Humans | Adolescent | Causes of | Practice guidelines (Medicine) | Care and treatment | Diagnosis | Diabetes in children
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10. Full Text GAD65 Antigen Therapy in Recently Diagnosed Type 1 Diabetes Mellitus
by Ludvigsson, Johnny and Krisky, David and Casas, Rosaura and Battelino, Tadej and Castaño, Luis and Greening, James and Kordonouri, Olga and Otonkoski, Timo and Pozzilli, Paolo and Robert, Jean-Jacques and Veeze, Henk J and Palmer, Jerry and Pediatrik and Barn- och ungdomskliniken i Linköping and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Barn- och ungdomskliniken i Norrköping and Barn- och kvinnocentrum and Östergötlands Läns Landsting and Hälsouniversitetet
The New England Journal of Medicine, ISSN 0028-4793, 02/2012, Volume 366, Issue 5, pp. 433 - 442
This trial assessed alum-formulated glutamic acid decarboxylase, the 65-kD isoform (GAD65), a major autoantigen in type 1 diabetes. In patients with... 
PROTEIN PEPTIDE DIAPEP277 | MEDICINE, GENERAL & INTERNAL | DOUBLE-BLIND TRIAL | RECENT-ONSET | RECOMMENDATIONS | LONG-TERM COMPLICATIONS | INSULIN-SECRETION | C-PEPTIDE | KETOACIDOSIS | BETA-CELL FUNCTION | CHILDREN | C-Peptide - blood | Autoantibodies - blood | Humans | Male | Diabetes Mellitus, Type 1 - drug therapy | Young Adult | Diabetes Mellitus, Type 1 - blood | Glutamate Decarboxylase - adverse effects | Glutamate Decarboxylase - therapeutic use | Protein Isoforms | Adolescent | Female | Diabetes Mellitus, Type 1 - immunology | Glutamate Decarboxylase - immunology | Child | Care and treatment | Type 1 diabetes | Autoantigens | Glutamate decarboxylase | Research | Diagnosis | Health aspects | Glutamic acid | Autoantibodies | Fasting | Peptides | Diabetes mellitus | Aluminum sulfate | Diabetes mellitus (insulin dependent) | Hypoglycemia | Patients | Insulin | Immunological tolerance | Studies | Beta cells | Injections | Hemoglobin | Diabetes | Informatics | Age | Index Medicus | Abridged Index Medicus | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
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11. Full Text The PILGRIM Study: In Silico Modeling of a Predictive Low Glucose Management System and Feasibility in Youth with Type 1 Diabetes During Exercise
by Danne, Thomas and Tsioli, Christiana and Kordonouri, Olga and Blaesig, Sarah and Remus, Kerstin and Roy, Anirban and Keenan, Barry and Lee, Scott W and Kaufman, Francine R
Diabetes Technology & Therapeutics, ISSN 1520-9156, 06/2014, Volume 16, Issue 6, pp. 338 - 347
Background: Predictive low glucose management (PLGM) may help prevent hypoglycemia by stopping insulin pump delivery based on predicted sensor glucose values.... 
Original Articles | AUTOMATED INSULIN SUSPENSION | ARTIFICIAL PANCREAS | NOCTURNAL HYPOGLYCEMIA | BASAL INSULIN | ADOLESCENTS | ENDOCRINOLOGY & METABOLISM | PREVENTION | ALARM ALGORITHMS | AUGMENTED PUMP THERAPY | MONITORING-SYSTEM | CHILDREN | Diabetes Mellitus, Type 1 - physiopathology | Glycated Hemoglobin A - metabolism | Humans | Insulin Infusion Systems - adverse effects | Insulin - administration & dosage | Male | Diabetes Mellitus, Type 1 - drug therapy | Feasibility Studies | Monitoring, Ambulatory | Cross-Over Studies | Hypoglycemia - prevention & control | Young Adult | Exercise | Hypoglycemic Agents - administration & dosage | Computer Simulation | Diabetes Mellitus, Type 1 - blood | Adolescent | Biosensing Techniques | Female | Blood Glucose - metabolism | Hypoglycemia - chemically induced | Hypoglycemic Agents - adverse effects | Insulin - adverse effects | Hyperglycemia | Glucose | Sensors | Diabetes | Insulin | Index Medicus
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12. Full Text Faster‐acting insulin aspart provides faster onset and greater early exposure vs insulin aspart in children and adolescents with type 1 diabetes mellitus
by Fath, Maryam and Danne, Thomas and Biester, Torben and Erichsen, Lars and Kordonouri, Olga and Haahr, Hanne
Pediatric Diabetes, ISSN 1399-543X, 12/2017, Volume 18, Issue 8, pp. 903 - 910
BackgroundFaster-acting insulin aspart (faster aspart) is insulin aspart (IAsp) in a new formulation with additional excipients (L-arginine and niacinamide).... 
pharmacokinetics | type 1 diabetes mellitus | adolescents | children | pharmacodynamics | STATEMENT | GLYCEMIC CONTROL | INTERNATIONAL-SOCIETY | APPEARANCE | T1D | TRIAL | GLUCOSE | ENDOCRINOLOGY & METABOLISM | PEDIATRICS | PUMP THERAPY | ASSOCIATION | Niacinamide | Arginine | Type 1 diabetes | Insulin | Adolescence | Diabetes mellitus | Body weight | Teenagers | Diabetes | Children | Age | Index Medicus
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13. Full Text Hypomethylation of multiple imprinted loci in individuals with transient neonatal diabetes is associated with mutations in ZFP57
by Boonen, Susanne E and Goodship, Judith A and Storr, John and Callaway, Jonathan L A and Temple, I Karen and Hahnemann, Johanne M D and Robinson, David O and Mackay, Deborah J G and Dayanikli, Pinar and Marks, Sophie M and White, Helen E and Ellard, Sian and Kordonouri, Olga and Masoud, Ahmed F and Hattersley, Andrew T and Oestergaard, Elsebet and Acerini, Carlo L and Firth, Helen V and Haemers, Andreas P
Nature Genetics, ISSN 1061-4036, 08/2008, Volume 40, Issue 8, pp. 949 - 951
We have previously described individuals presenting with transient neonatal diabetes and showing a variable pattern of DNA hypomethylation at imprinted loci... 
ZFP-57 | STEM-CELLS | MELLITUS | IDENTIFICATION | GENETICS & HEREDITY | REGION | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Genomic Imprinting | DNA Methylation | Zinc Fingers | Diabetes Mellitus - genetics | Humans | Mutation | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Infant, Newborn | Gene mutations | Analysis | Genetic aspects | Research | Diabetes | Methylation | Gene expression | Genetics | Amino acids | Gene loci | Chromosomes | Index Medicus
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14. Full Text Closed-loop glucose control in young people with type 1 diabetes during and after unannounced physical activity: a randomised controlled crossover trial
by Dovc, Klemen and Macedoni, Maddalena and Bratina, Natasa and Lepej, Dusanka and Nimri, Revital and Atlas, Eran and Muller, Ido and Kordonouri, Olga and Biester, Torben and Danne, Thomas and Phillip, Moshe and Battelino, Tadej
Diabetologia, ISSN 0012-186X, 11/2017, Volume 60, Issue 11, pp. 2157 - 2167
Hypoglycaemia during and after exercise remains a challenge. The present study evaluated the safety and efficacy of closed-loop insulin delivery during... 
Exercise | Medicine & Public Health | Human Physiology | Hypoglycaemia | Metabolic Diseases | Internal Medicine | Clinical science | Devices | Diabetes in childhood | GLYCEMIC CONTROL | PREVENTION | OVERNIGHT | ADULTS | ARTIFICIAL PANCREAS SYSTEM | CHILDREN | ADOLESCENTS | ENDOCRINOLOGY & METABOLISM | HYPOGLYCEMIA | BASAL INSULIN DELIVERY | Cross-Over Studies | Diabetes Mellitus, Type 1 - blood | Diabetes Mellitus, Type 1 - physiopathology | Humans | Adolescent | Female | Male | Exercise - physiology | Hypoglycemia - blood | Child | Physical fitness | Glucose | Type 1 diabetes | Dextrose | Diabetes therapy | Adolescence | Physical training | Physical activity | Diabetes mellitus | Diabetes | Children | Hypoglycemia | Insulin | Index Medicus
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15. Full Text Effects of dapagliflozin on insulin‐requirement, glucose excretion and ß‐hydroxybutyrate levels are not related to baseline HbA1c in youth with type 1 diabetes
by Biester, Torben and Aschemeier, Baerbel and Fath, Maryam and Frey, Marcel and Scheerer, Markus F and Kordonouri, Olga and Danne, Thomas
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 11/2017, Volume 19, Issue 11, pp. 1635 - 1639
Youth with type 1 diabetes ( T1D ) infrequently achieve HbA1c targets. Therefore, this placebo‐controlled, randomized, crossover study was set up to assess the... 
insulin requirement | type 1 diabetes | diabetic ketoacidosis | dapagliflozin | hypoglycemia | SGLT | 2 inhibitor | HbA1c | SGLT-2 inhibitor | Glycosuria - chemically induced | Benzhydryl Compounds - administration & dosage | Glycated Hemoglobin A - metabolism | Humans | Glycated Hemoglobin A - drug effects | Male | Glucosides - pharmacokinetics | Diabetes Mellitus, Type 1 - complications | Dose-Response Relationship, Drug | Young Adult | Adult | Female | Drug Therapy, Combination | Child | Benzhydryl Compounds - pharmacokinetics | Glucosides - pharmacology | Double-Blind Method | 3-Hydroxybutyric Acid - blood | Insulin - administration & dosage | Diabetes Mellitus, Type 1 - urine | Diabetes Mellitus, Type 1 - drug therapy | Cross-Over Studies | Glycosuria - epidemiology | Pilot Projects | Glucosides - administration & dosage | Diabetes Mellitus, Type 1 - blood | Adolescent | Benzhydryl Compounds - pharmacology | Insulin - pharmacokinetics | Insulin | Glucose | Diabetes | Index Medicus
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16. Full Text Outcomes of using flash glucose monitoring technology by children and young people with type 1 diabetes in a single arm study
by Campbell, Fiona M and Murphy, Nuala P and Stewart, Caroline and Biester, Torben and Kordonouri, Olga
Pediatric Diabetes, ISSN 1399-543X, 11/2018, Volume 19, Issue 7, pp. 1294 - 1301
Background and Objective: Outcomes of using flash glucose monitoring have been reported in adults. This trial evaluated use in children and teenagers with type... 
self‐monitoring | technology | glycated hemoglobin A1c | children | self-monitoring | SENSING TECHNOLOGY | ADULTS | PREVENTION | FOLLOW-UP | AUGMENTED PUMP THERAPY | RANDOMIZED CONTROLLED-TRIAL | SATISFACTION | ADOLESCENTS | ENDOCRINOLOGY & METABOLISM | HYPOGLYCEMIA | PEDIATRICS | ASSOCIATION | Body Mass Index | Wearable Electronic Devices - statistics & numerical data | Blood Glucose - analysis | Humans | Child, Preschool | Insulin - administration & dosage | Male | Hypoglycemic Agents - administration & dosage | Diabetes Mellitus, Type 1 - blood | Adolescent | Blood Glucose Self-Monitoring | Female | Child | Antihistamines | Usage | Hyperglycemia | Blood sugar monitoring