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BioEssays, ISSN 0265-9247, 10/2014, Volume 36, Issue 10, pp. 997 - 1004
Journal Article
NATURE GENETICS, ISSN 1061-4036, 12/2017, Volume 49, Issue 12, pp. 1673 - 1674
A new analysis of cancer genomes identifies a decrease in the mutation burden of exons, but not introns, as compared to expectation. This difference can be... 
DNA | MUTATION HOTSPOTS | GENES | GENETICS & HEREDITY | CHROMATIN ORGANIZATION | REVEAL | CANCER GENOMES | Genetic research | Research | Properties | Exon (Molecular genetics) | DNA mismatch repair | Introns | Exons | Genes | Bias | Genomes | DNA repair | Recruitment | Proteins | Studies | Mismatch repair | Evolution | Mutation | Repair | Deoxyribonucleic acid--DNA | Cancer | Tumors
Journal Article
Nature, ISSN 0028-0836, 02/2015, Volume 518, Issue 7539, pp. 360 - 364
Cancer is a disease potentiated by mutations in somatic cells. Cancer mutations are not distributed uniformly along the human genome. Instead, different human... 
HUMAN GENOME | SIGNATURES | ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | SOMATIC MUTATIONS | Chromatin | Gene mutations | Genetic research | Genetic aspects | Research | Health aspects | Cancer | Studies | Accuracy | Melanoma | Epigenetics | Genomes | Mutation | Gene expression | Deoxyribonucleic acid--DNA | Tumors | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 499, Issue 7457, pp. 214 - 218
Journal Article
Genome Research, ISSN 1088-9051, 08/2017, Volume 27, Issue 8, pp. 1406 - 1416
In dividing cells, DNA replication occurs in a precise order, but many questions remain regarding the mechanisms of replication timing establishment and... 
DANIO-RERIO | EMBRYONIC-DEVELOPMENT | CHROMATIN SIGNATURES | ZEBRAFISH | CHROMOSOMAL DOMAINS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DYNAMIC CHANGES | HISTONE ACETYLATION | HUMAN MUTATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | GENE-EXPRESSION | CELL-CYCLE | DNA replication | Usage | Research | X chromosome
Journal Article
Science, ISSN 0036-8075, 08/2015, Volume 349, Issue 6248, pp. 643 - 646
The germinal center (GC) is a microanatomical compartment wherein high-affinity antibody-producing B cells are selectively expanded. B cells proliferate and... 
IMMUNE-RESPONSE | CLONAL SELECTION | DENDRITIC CELLS | AFFINITY MATURATION | MULTIDISCIPLINARY SCIENCES | IN-VIVO | DYNAMICS | ANTIBODY-RESPONSES | HYPERMUTATION | CANCER | DNA-REPLICATION | Physiological aspects | B cells | T cells | Analysis | Cell cycle | Lymphocytes | Immune system | Origins | Genes | Antibodies | Replication | Affinity | Mice | Transit | Protective
Journal Article
Journal Article
Genome Research, ISSN 1088-9051, 01/2014, Volume 24, Issue 1, pp. 64 - 69
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2017, Volume 23, Issue 7, pp. 1733 - 1747
Purpose: To explore the functional consequences of possible cross-talk between the CXCR4/CXCL12 and the sphingosine-1phosphate (S1P) pathways in multiple... 
CHRONIC MYELOGENOUS LEUKEMIA | PROGENITOR CELLS | CXCR4 ANTAGONIST BKT140 | IN-VITRO | BONE-MARROW MICROENVIRONMENT | CANCER CELLS | CARCINOMA CELLS | ONCOLOGY | MANTLE CELL LYMPHOMA | UP-REGULATION | SPHINGOSINE 1-PHOSPHATE | DNA Damage - drug effects | Lysophospholipids - metabolism | Apoptosis - drug effects | Humans | Phosphotransferases (Alcohol Group Acceptor) - genetics | Drug Synergism | Xenograft Model Antitumor Assays | Phosphotransferases (Alcohol Group Acceptor) - antagonists & inhibitors | Lysophospholipids - genetics | Multiple Myeloma - drug therapy | Multiple Myeloma - pathology | Sphingosine - analogs & derivatives | Animals | Chemokine CXCL12 - genetics | Bortezomib - administration & dosage | Signal Transduction - drug effects | Sphingosine - genetics | Receptors, CXCR4 - genetics | Mice | Sphingosine - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Multiple Myeloma - genetics | Fingolimod Hydrochloride - administration & dosage | Phosphates | CXCL12 protein | Bortezomib | DNA damage | Multiple myeloma | Cytotoxicity | Cell surface | CXCR4 protein | Sphingosine 1-phosphate | Signal transduction | Signaling | Sensitivity | Pathways | Experimental design | FTY720 | Cell lines | Xenografts | Bone marrow | Inhibition | Cell migration | Deoxyribonucleic acid--DNA | Cancer | Apoptosis
Journal Article