Journal of Chromatography B, ISSN 1570-0232, 04/2016, Volume 1019, pp. 202 - 209
We describe a relatively convenient and reliable procedure for assessing the magnitude of free radical-mediated (chain) lipid peroxidation in biological...
Lipid peroxidation | Thin layer chromatography | Free radicals | Phosphorimaging | Cholesterol | Cholesterol oxides | OXIDATION | CHEMISTRY, ANALYTICAL | HYPERRESISTANCE | TURNOVER | MECHANISM | GLUTATHIONE-PEROXIDASE | BIOCHEMICAL RESEARCH METHODS | PERFORMANCE LIQUID-CHROMATOGRAPHY | NITRIC-OXIDE INHIBITION | CELL-MEMBRANES | HYDROPEROXIDES | Free Radicals - chemistry | Chromatography, Thin Layer - methods | Humans | Lipoproteins - chemistry | Cholesterol - metabolism | Cell Membrane - chemistry | Cholesterol - chemistry | Liposomes - chemistry | Photochemistry - methods | Lipoproteins - metabolism | Free Radicals - metabolism | Liposomes - metabolism | Cell Membrane - metabolism | Lipid Peroxidation | Blood lipids | Investigations | Epoxy resins | Low density lipoproteins | Oxides | Peroxidase | Free radicals (Chemistry) | High performance liquid chromatography | Cells | Membranes | Lipoproteins | Lipids | Iron | Biological | Mammals | Chemical compounds | phosphorimaging | free radicals | cholesterol oxides | lipid peroxidation | thin layer chromatography
Lipid peroxidation | Thin layer chromatography | Free radicals | Phosphorimaging | Cholesterol | Cholesterol oxides | OXIDATION | CHEMISTRY, ANALYTICAL | HYPERRESISTANCE | TURNOVER | MECHANISM | GLUTATHIONE-PEROXIDASE | BIOCHEMICAL RESEARCH METHODS | PERFORMANCE LIQUID-CHROMATOGRAPHY | NITRIC-OXIDE INHIBITION | CELL-MEMBRANES | HYDROPEROXIDES | Free Radicals - chemistry | Chromatography, Thin Layer - methods | Humans | Lipoproteins - chemistry | Cholesterol - metabolism | Cell Membrane - chemistry | Cholesterol - chemistry | Liposomes - chemistry | Photochemistry - methods | Lipoproteins - metabolism | Free Radicals - metabolism | Liposomes - metabolism | Cell Membrane - metabolism | Lipid Peroxidation | Blood lipids | Investigations | Epoxy resins | Low density lipoproteins | Oxides | Peroxidase | Free radicals (Chemistry) | High performance liquid chromatography | Cells | Membranes | Lipoproteins | Lipids | Iron | Biological | Mammals | Chemical compounds | phosphorimaging | free radicals | cholesterol oxides | lipid peroxidation | thin layer chromatography
Journal Article
Photochemistry and Photobiology, ISSN 0031-8655, 01/2019, Volume 95, Issue 1, pp. 73 - 82
Like other unsaturated lipids in cell membranes and lipoproteins, cholesterol (Ch) is susceptible to oxidative modification, including photodynamic oxidation....
PERFORMANCE LIQUID-CHROMATOGRAPHY | REDUCTIVE TURNOVER | INTERMEMBRANE TRANSFER | STEROL-METABOLISM | BIOPHYSICS | SINGLET MOLECULAR-OXYGEN | HYDROPEROXIDE TRAFFICKING | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLUTATHIONE-PEROXIDASE | TUMOR-SUPPRESSOR | HYDROGEN-PEROXIDE | CELL-MEMBRANES | Cholesterol - chemistry | Oxidation-Reduction | Oxidative Stress | Signal Transduction | Lipid Peroxides - chemistry | Electrons | Photochemical Processes | Translocation | Membranes | Hydrogen peroxide | Photochemical reactions | Free radicals | Lipid peroxidation | Oxides | Lipids | Photochemicals | Cell membranes | Isomers | Cholesterol | Alcohols | Intermediates | Signaling | Reduction | Lipoproteins | Singlet oxygen | Oxidation | Photooxidation | Peroxidation | Structure-function relationships
PERFORMANCE LIQUID-CHROMATOGRAPHY | REDUCTIVE TURNOVER | INTERMEMBRANE TRANSFER | STEROL-METABOLISM | BIOPHYSICS | SINGLET MOLECULAR-OXYGEN | HYDROPEROXIDE TRAFFICKING | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLUTATHIONE-PEROXIDASE | TUMOR-SUPPRESSOR | HYDROGEN-PEROXIDE | CELL-MEMBRANES | Cholesterol - chemistry | Oxidation-Reduction | Oxidative Stress | Signal Transduction | Lipid Peroxides - chemistry | Electrons | Photochemical Processes | Translocation | Membranes | Hydrogen peroxide | Photochemical reactions | Free radicals | Lipid peroxidation | Oxides | Lipids | Photochemicals | Cell membranes | Isomers | Cholesterol | Alcohols | Intermediates | Signaling | Reduction | Lipoproteins | Singlet oxygen | Oxidation | Photooxidation | Peroxidation | Structure-function relationships
Journal Article
CURRENT MEDICINAL CHEMISTRY, ISSN 0929-8673, 2016, Volume 23, Issue 24, pp. 2754 - 2769
Photodynamic therapy (PDT) is a unique site-specific treatment for eradicating a variety of solid tumors, including prostate, lung, bladder, and brain tumors....
CHEMISTRY, MEDICINAL | apoptosis resistance | ACTIVATED PROTEIN-KINASE | LIPID-PEROXIDATION | photodynamic therapy | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-CELLS | bystander effects | inducible nitric oxide synthase | RADIATION-INDUCED APOPTOSIS | CYTOPROTECTIVE MECHANISMS | MEDIATED CHOLESTEROL PEROXIDATION | S-NITROSYLATION | LUNG-CANCER | SYNTHASE INHIBITION | Nitric oxide | PHARMACOLOGY & PHARMACY | cancer | cell migration/invasion | UP-REGULATION | Aminolevulinic Acid - chemistry | Photosensitizing Agents - chemistry | Photosensitizing Agents - therapeutic use | Apoptosis - drug effects | Humans | Aminolevulinic Acid - pharmacology | Protoporphyrins - pharmacology | Aminolevulinic Acid - therapeutic use | Photochemotherapy | Neoplasms - drug therapy | Photosensitizing Agents - pharmacology | Animals | Nitric Oxide Synthase Type II - antagonists & inhibitors | Light | Protoporphyrins - chemistry | Nitric Oxide - metabolism | Protoporphyrins - therapeutic use | Nitric Oxide Synthase Type II - metabolism
CHEMISTRY, MEDICINAL | apoptosis resistance | ACTIVATED PROTEIN-KINASE | LIPID-PEROXIDATION | photodynamic therapy | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-CELLS | bystander effects | inducible nitric oxide synthase | RADIATION-INDUCED APOPTOSIS | CYTOPROTECTIVE MECHANISMS | MEDIATED CHOLESTEROL PEROXIDATION | S-NITROSYLATION | LUNG-CANCER | SYNTHASE INHIBITION | Nitric oxide | PHARMACOLOGY & PHARMACY | cancer | cell migration/invasion | UP-REGULATION | Aminolevulinic Acid - chemistry | Photosensitizing Agents - chemistry | Photosensitizing Agents - therapeutic use | Apoptosis - drug effects | Humans | Aminolevulinic Acid - pharmacology | Protoporphyrins - pharmacology | Aminolevulinic Acid - therapeutic use | Photochemotherapy | Neoplasms - drug therapy | Photosensitizing Agents - pharmacology | Animals | Nitric Oxide Synthase Type II - antagonists & inhibitors | Light | Protoporphyrins - chemistry | Nitric Oxide - metabolism | Protoporphyrins - therapeutic use | Nitric Oxide Synthase Type II - metabolism
Journal Article
Cell Biochemistry and Biophysics, ISSN 1085-9195, 12/2017, Volume 75, Issue 3, pp. 413 - 419
Cholesterol is like other unsaturated lipids in being susceptible to peroxidative degradation upon exposure to strong oxidants like hydroxyl radical or...
Life Sciences | Biochemistry, general | Biotechnology | Reactive oxygen species | Hydroperoxide translocation | Biological and Medical Physics, Biophysics | Glutathione peroxidase-type 4 | Pharmacology/Toxicology | Chain lipid peroxidation | Cholesterol | Cell Biology | Cholesterol hydroperoxide | OXIDATIVE-STRESS | Glutathione peroxidase-type | STEROL CARRIER | LIPID-PEROXIDATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLUTATHIONE-PEROXIDASE | LOW-DENSITY-LIPOPROTEIN | CATHODE ELECTROCHEMICAL DETECTION | CELL BIOLOGY | PERFORMANCE LIQUID-CHROMATOGRAPHY | INTERMEMBRANE TRANSFER | BIOPHYSICS | EFFECTOR ACTION | SINGLET OXYGEN | Cholesterol - chemistry | Cholesterol - analogs & derivatives | Glutathione Peroxidase - metabolism | Lipids - chemistry | Liposomes - chemistry | Animals | Oxidation-Reduction | Signal Transduction | Liposomes - metabolism | Cholesterol - metabolism | Lipid Peroxidation | Antioxidants | Thiols | Hydroxides | Active oxygen | Cell death | Lipids | Peroxidase | Oxidative stress | Atherogenesis | Oxidizing agents | Lipid peroxidation | Iron | Phospholipids | Reduction | Oxidants | Hydroxyl radicals | Oxidation | Containment | Peroxidation | Translocation | Peroxynitrite | Intermediates | Lipoproteins | Singlet oxygen | Structural damage | Cellular structure | Electrons | Structure-function relationships | cholesterol | cholesterol hydroperoxide | hydroperoxide translocation | glutathione peroxidase-type 4 | chain lipid peroxidation
Life Sciences | Biochemistry, general | Biotechnology | Reactive oxygen species | Hydroperoxide translocation | Biological and Medical Physics, Biophysics | Glutathione peroxidase-type 4 | Pharmacology/Toxicology | Chain lipid peroxidation | Cholesterol | Cell Biology | Cholesterol hydroperoxide | OXIDATIVE-STRESS | Glutathione peroxidase-type | STEROL CARRIER | LIPID-PEROXIDATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLUTATHIONE-PEROXIDASE | LOW-DENSITY-LIPOPROTEIN | CATHODE ELECTROCHEMICAL DETECTION | CELL BIOLOGY | PERFORMANCE LIQUID-CHROMATOGRAPHY | INTERMEMBRANE TRANSFER | BIOPHYSICS | EFFECTOR ACTION | SINGLET OXYGEN | Cholesterol - chemistry | Cholesterol - analogs & derivatives | Glutathione Peroxidase - metabolism | Lipids - chemistry | Liposomes - chemistry | Animals | Oxidation-Reduction | Signal Transduction | Liposomes - metabolism | Cholesterol - metabolism | Lipid Peroxidation | Antioxidants | Thiols | Hydroxides | Active oxygen | Cell death | Lipids | Peroxidase | Oxidative stress | Atherogenesis | Oxidizing agents | Lipid peroxidation | Iron | Phospholipids | Reduction | Oxidants | Hydroxyl radicals | Oxidation | Containment | Peroxidation | Translocation | Peroxynitrite | Intermediates | Lipoproteins | Singlet oxygen | Structural damage | Cellular structure | Electrons | Structure-function relationships | cholesterol | cholesterol hydroperoxide | hydroperoxide translocation | glutathione peroxidase-type 4 | chain lipid peroxidation
Journal Article
5.
Full Text
Bystander Effects of Nitric Oxide in Cellular Models of Anti-Tumor Photodynamic Therapy
Cancers, ISSN 2072-6694, 10/2019, Volume 11, Issue 11, p. 1674
Tumor cells exposed to stress-inducing radiotherapy or chemotherapy can send signals to non- or minimally exposed bystander cells. Bystander effects of...
nitric oxide | bystander effects | photodynamic therapy | inducible nitric oxide synthase
nitric oxide | bystander effects | photodynamic therapy | inducible nitric oxide synthase
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2011, Volume 286, Issue 30, pp. 26334 - 26343
Cytochrome c (cyt c) release upon oxidation of cardiolipin (CL) in the mitochondrial inner membrane (IM) under oxidative stress occurs early in the intrinsic...
PERFORMANCE LIQUID-CHROMATOGRAPHY | 5-AMINOLEVULINATE-TREATED TUMOR-CELLS | INTERMEMBRANE TRANSFER | YEAST MITOCHONDRIA | CONTACT SITE | LIPID-PEROXIDATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CATHODE ELECTROCHEMICAL DETECTION | MEDIATED APOPTOSIS | CYTOCHROME-C RELEASE | BCL-2 FAMILY | Oxidation-Reduction | Saccharomyces cerevisiae - genetics | Humans | Lipid Peroxides - genetics | bcl-2-Associated X Protein - metabolism | BH3 Interacting Domain Death Agonist Protein - genetics | Cardiolipins - metabolism | Lipid Peroxides - metabolism | Mitochondria - metabolism | Permeability | Mitochondrial Membranes - metabolism | Saccharomyces cerevisiae - metabolism | Animals | Mitochondria - genetics | Mice | Mutation | BH3 Interacting Domain Death Agonist Protein - metabolism | bcl-2-Associated X Protein - genetics | Apoptosis | Cardiolipins - genetics | Signal Transduction | Mitochondrial Apoptosis | Oxidative Stress | Lipid Oxidation | Lipid Translocation | Phospholipid | Phospholipid Vesicle | Membrane Lipids | Oxygen Toxicity | Cardiolipin Oxidation | Lipid Peroxidation
PERFORMANCE LIQUID-CHROMATOGRAPHY | 5-AMINOLEVULINATE-TREATED TUMOR-CELLS | INTERMEMBRANE TRANSFER | YEAST MITOCHONDRIA | CONTACT SITE | LIPID-PEROXIDATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CATHODE ELECTROCHEMICAL DETECTION | MEDIATED APOPTOSIS | CYTOCHROME-C RELEASE | BCL-2 FAMILY | Oxidation-Reduction | Saccharomyces cerevisiae - genetics | Humans | Lipid Peroxides - genetics | bcl-2-Associated X Protein - metabolism | BH3 Interacting Domain Death Agonist Protein - genetics | Cardiolipins - metabolism | Lipid Peroxides - metabolism | Mitochondria - metabolism | Permeability | Mitochondrial Membranes - metabolism | Saccharomyces cerevisiae - metabolism | Animals | Mitochondria - genetics | Mice | Mutation | BH3 Interacting Domain Death Agonist Protein - metabolism | bcl-2-Associated X Protein - genetics | Apoptosis | Cardiolipins - genetics | Signal Transduction | Mitochondrial Apoptosis | Oxidative Stress | Lipid Oxidation | Lipid Translocation | Phospholipid | Phospholipid Vesicle | Membrane Lipids | Oxygen Toxicity | Cardiolipin Oxidation | Lipid Peroxidation
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 01/2017, Volume 102, pp. 111 - 121
The bystander effects of anti-cancer ionizing radiation have been widely studied, but far less is known about such effects in the case of non-ionizing...
Inducible NO synthase | Bystander effects | Photodynamic therapy | Nitric oxide | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOUBLE-STRAND BREAKS | INDUCTION | SYNTHASE | CHALLENGE | INHIBITION | IN-VIVO | GROWTH | ENDOCRINOLOGY & METABOLISM | CANCER PROGRESSION | UP-REGULATION | Apoptosis - drug effects | Apoptosis - radiation effects | Humans | Imidazoles - administration & dosage | Male | NF-kappa B - metabolism | Photochemotherapy | Benzylamines - administration & dosage | Gene Knockdown Techniques | Enzyme Inhibitors - administration & dosage | Protoporphyrins - genetics | Prostatic Neoplasms - genetics | Cyclooxygenase 2 - genetics | Light | Bystander Effect - radiation effects | Prostatic Neoplasms - pathology | Protoporphyrins - metabolism | Benzoates - administration & dosage | Cell Movement - radiation effects | Cell Movement - drug effects | Amidines - administration & dosage | NF-kappa B - genetics | Nitric Oxide Synthase Type II - genetics | Nitric Oxide - genetics | Cyclooxygenase 2 - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Gene Expression Regulation, Neoplastic - radiation effects | Nitric Oxide - metabolism | Cell Proliferation - radiation effects | Nitric Oxide Synthase Type II - metabolism | Proteins | Medical colleges | Ionizing radiation | Prostate cancer | Protein kinases | Cancer | Tumors
Inducible NO synthase | Bystander effects | Photodynamic therapy | Nitric oxide | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOUBLE-STRAND BREAKS | INDUCTION | SYNTHASE | CHALLENGE | INHIBITION | IN-VIVO | GROWTH | ENDOCRINOLOGY & METABOLISM | CANCER PROGRESSION | UP-REGULATION | Apoptosis - drug effects | Apoptosis - radiation effects | Humans | Imidazoles - administration & dosage | Male | NF-kappa B - metabolism | Photochemotherapy | Benzylamines - administration & dosage | Gene Knockdown Techniques | Enzyme Inhibitors - administration & dosage | Protoporphyrins - genetics | Prostatic Neoplasms - genetics | Cyclooxygenase 2 - genetics | Light | Bystander Effect - radiation effects | Prostatic Neoplasms - pathology | Protoporphyrins - metabolism | Benzoates - administration & dosage | Cell Movement - radiation effects | Cell Movement - drug effects | Amidines - administration & dosage | NF-kappa B - genetics | Nitric Oxide Synthase Type II - genetics | Nitric Oxide - genetics | Cyclooxygenase 2 - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Gene Expression Regulation, Neoplastic - radiation effects | Nitric Oxide - metabolism | Cell Proliferation - radiation effects | Nitric Oxide Synthase Type II - metabolism | Proteins | Medical colleges | Ionizing radiation | Prostate cancer | Protein kinases | Cancer | Tumors
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2018, Volume 128, pp. S69 - S69
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2018, Volume 128, pp. S29 - S30
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2018, Volume 128, p. S69
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2018, Volume 128, pp. S29 - S30
Journal Article
Current Medicinal Chemistry, ISSN 0929-8673, 07/2016, Volume 23, Issue 24, pp. 2754 - 2769
Journal Article
Photochemistry and Photobiology, ISSN 0031-8655, 11/2016, Volume 92, Issue 6, pp. 842 - 853
Gliomas are aggressive brain tumors that are resistant to conventional chemotherapy and radiotherapy. Much of this resistance is attributed to endogenous...
MATRIX METALLOPROTEINASES | IN-VITRO | INVASION | BIOPHYSICS | SYNTHASE INHIBITION | GLIOMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL PROLIFERATION | MALIGNANT BRAIN-TUMORS | UP-REGULATION | CANCER | EXPRESSION | Cell Survival - drug effects | Adjuvants, Pharmaceutic - pharmacology | Apoptosis - drug effects | Apoptosis - radiation effects | Nitric Oxide - antagonists & inhibitors | Humans | Aminolevulinic Acid - pharmacology | Aminolevulinic Acid - therapeutic use | Cell Survival - radiation effects | Photochemotherapy | Glioblastoma - therapy | Adjuvants, Pharmaceutic - therapeutic use | Animals | Nitric Oxide Synthase Type II - antagonists & inhibitors | Cell Line, Tumor | Glioblastoma multiforme | Analysis | Nitric oxide | Cancer | Pharmacology | Photodynamic therapy | Brain cancer
MATRIX METALLOPROTEINASES | IN-VITRO | INVASION | BIOPHYSICS | SYNTHASE INHIBITION | GLIOMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL PROLIFERATION | MALIGNANT BRAIN-TUMORS | UP-REGULATION | CANCER | EXPRESSION | Cell Survival - drug effects | Adjuvants, Pharmaceutic - pharmacology | Apoptosis - drug effects | Apoptosis - radiation effects | Nitric Oxide - antagonists & inhibitors | Humans | Aminolevulinic Acid - pharmacology | Aminolevulinic Acid - therapeutic use | Cell Survival - radiation effects | Photochemotherapy | Glioblastoma - therapy | Adjuvants, Pharmaceutic - therapeutic use | Animals | Nitric Oxide Synthase Type II - antagonists & inhibitors | Cell Line, Tumor | Glioblastoma multiforme | Analysis | Nitric oxide | Cancer | Pharmacology | Photodynamic therapy | Brain cancer
Journal Article
Current Medicinal Chemistry, ISSN 0929-8673, 07/2016, Volume 23, Issue 24, p. 2754
Photodynamic therapy (PDT) is a unique site-specific treatment for eradicating a variety of solid tumors, including prostate, lung, bladder, and brain tumors....
Brain | Reactive oxygen species | Animal models | Brain tumors | Radiation | Bladder | Aminolevulinic acid | Antagonism | Protoporphyrin | Urinary bladder | Infrared radiation | Photoexcitation | Oxygen | Photodynamic therapy | Tumor cells | Adjuvants | I.R. radiation | Breast cancer | Nitric-oxide synthase | Side effects | Singlet oxygen | Inhibitors | Lungs | Nitric oxide | Photosensitization | Irradiation | Solid tumors | Prostate cancer | Prostate | Cancer | Tumors | Apoptosis
Brain | Reactive oxygen species | Animal models | Brain tumors | Radiation | Bladder | Aminolevulinic acid | Antagonism | Protoporphyrin | Urinary bladder | Infrared radiation | Photoexcitation | Oxygen | Photodynamic therapy | Tumor cells | Adjuvants | I.R. radiation | Breast cancer | Nitric-oxide synthase | Side effects | Singlet oxygen | Inhibitors | Lungs | Nitric oxide | Photosensitization | Irradiation | Solid tumors | Prostate cancer | Prostate | Cancer | Tumors | Apoptosis
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 06/2019, Volume 137, pp. 37 - 45
Nitric oxide (NO) generated endogenously by inducible nitric oxide synthase (iNOS) promotes growth and migration/invasion of glioblastoma cells and also...
Oxidative stress | Photodynamic therapy | Stress signaling | Nitric oxide | Inducible nitric oxide synthase | Glioblastoma | CANCER-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | AKT | MALIGNANT BRAIN-TUMORS | HISTONE ACETYLTRANSFERASE | SYNTHASE | THERAPY | PATHWAY | ENDOCRINOLOGY & METABOLISM | NF-KAPPA-B | UP-REGULATION | Chemotherapy | Active oxygen | Lysine | Glioblastoma multiforme | Cancer
Oxidative stress | Photodynamic therapy | Stress signaling | Nitric oxide | Inducible nitric oxide synthase | Glioblastoma | CANCER-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | AKT | MALIGNANT BRAIN-TUMORS | HISTONE ACETYLTRANSFERASE | SYNTHASE | THERAPY | PATHWAY | ENDOCRINOLOGY & METABOLISM | NF-KAPPA-B | UP-REGULATION | Chemotherapy | Active oxygen | Lysine | Glioblastoma multiforme | Cancer
Journal Article
FEBS Letters, ISSN 0014-5793, 01/2014, Volume 588, Issue 1, pp. 65 - 70
StAR family proteins in vascular macrophages participate in reverse cholesterol transport (RCT). We hypothesize that under pathophysiological oxidative stress,...
StAR protein | Oxidative stress | Reverse cholesterol transport | Cholesterol hydroperoxide | Macrophage | 7α-OOH | db-cAMP | 3-(4,5-dimethylthiazolyl-2-yl)-2,5-diphenyltetrazolium bromide | 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethyl-benzimidazolylcarbocyanine iodide | ATP binding cassette transporter A1 | phosphate-buffered saline | MTT | 3β-hydroxycholest-5-ene-7α-hydroperoxide | StarD4 | 1-palmitoyl-2-sn-glycero-3-phosphocholine | dibutyryl-cAMP | POPC | 7α-OH | ChOOH(s) | cholest-5-ene-3β,7α-diol | ABCA1 | PBS | 4,4-difluoro-5-(4-phenyl-1,3-butadienyl)-4-bora-3a,4a-diaza-s-inda-cene-3-undecanoic acid | cholesterol hydroperoxide(s) | small unilamellar vesicle(s) | StarD1 | type-4 steroidogenic acute regulatory domain protein | type-1 steroidogenic acute regulatory domain protein | C11-BODIPY | SUV(s) | JC-1 | ATHEROSCLEROTIC LESIONS | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | LOW-DENSITY-LIPOPROTEIN | TRAFFICKING | CELL BIOLOGY | EFFLUX | BIOPHYSICS | EFFECTOR ACTION | PROTEINS | EXPRESSION | Oxidative Stress | Membrane Potential, Mitochondrial - drug effects | Phosphoproteins - metabolism | ATP Binding Cassette Transporter 1 - metabolism | Dose-Response Relationship, Drug | RNA Interference | Time Factors | Lipid Peroxidation - drug effects | Biological Transport - drug effects | Cell Membrane - metabolism | Cell Membrane - drug effects | Cell Line | Cell Survival - drug effects | Cholesterol - analogs & derivatives | Mitochondria - metabolism | Macrophages - cytology | Phosphoproteins - genetics | Cholesterol - metabolism | Blotting, Western | Macrophages - metabolism | Animals | Cholesterol - pharmacology | Macrophages - drug effects | Bucladesine - pharmacology | Mice | Macrophages | Cholesterol
StAR protein | Oxidative stress | Reverse cholesterol transport | Cholesterol hydroperoxide | Macrophage | 7α-OOH | db-cAMP | 3-(4,5-dimethylthiazolyl-2-yl)-2,5-diphenyltetrazolium bromide | 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethyl-benzimidazolylcarbocyanine iodide | ATP binding cassette transporter A1 | phosphate-buffered saline | MTT | 3β-hydroxycholest-5-ene-7α-hydroperoxide | StarD4 | 1-palmitoyl-2-sn-glycero-3-phosphocholine | dibutyryl-cAMP | POPC | 7α-OH | ChOOH(s) | cholest-5-ene-3β,7α-diol | ABCA1 | PBS | 4,4-difluoro-5-(4-phenyl-1,3-butadienyl)-4-bora-3a,4a-diaza-s-inda-cene-3-undecanoic acid | cholesterol hydroperoxide(s) | small unilamellar vesicle(s) | StarD1 | type-4 steroidogenic acute regulatory domain protein | type-1 steroidogenic acute regulatory domain protein | C11-BODIPY | SUV(s) | JC-1 | ATHEROSCLEROTIC LESIONS | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | LOW-DENSITY-LIPOPROTEIN | TRAFFICKING | CELL BIOLOGY | EFFLUX | BIOPHYSICS | EFFECTOR ACTION | PROTEINS | EXPRESSION | Oxidative Stress | Membrane Potential, Mitochondrial - drug effects | Phosphoproteins - metabolism | ATP Binding Cassette Transporter 1 - metabolism | Dose-Response Relationship, Drug | RNA Interference | Time Factors | Lipid Peroxidation - drug effects | Biological Transport - drug effects | Cell Membrane - metabolism | Cell Membrane - drug effects | Cell Line | Cell Survival - drug effects | Cholesterol - analogs & derivatives | Mitochondria - metabolism | Macrophages - cytology | Phosphoproteins - genetics | Cholesterol - metabolism | Blotting, Western | Macrophages - metabolism | Animals | Cholesterol - pharmacology | Macrophages - drug effects | Bucladesine - pharmacology | Mice | Macrophages | Cholesterol
Journal Article
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 2005, Volume 433, Issue 2, pp. 435 - 446
In 5-aminolevulinic acid (ALA)-based photodynamic therapy (PDT), ALA taken up by tumor cells is metabolized to protoporphyrin IX (PpIX), which sensitizes...
Lipid peroxidation | Photodynamic therapy | Cardiolipin | Aminolevulinic acid | Apoptosis | LIPID-PEROXIDATION | CHOLESTEROL | photodynamic therapy | BIOCHEMISTRY & MOLECULAR BIOLOGY | MEMBRANES | apoptosis | DEATH | RELEASE | HYDROPEROXIDE GLUTATHIONE-PEROXIDASE | CHROMATOGRAPHY | cardiolipin | lipid peroxidation | CYTOCHROME-C | BIOPHYSICS | aminolevulinic acid | SINGLET OXYGEN | Mitochondria - enzymology | Apoptosis - drug effects | Epithelial Cells - drug effects | Humans | Caspases - analysis | Chromatography, High Pressure Liquid | Photochemotherapy | Photosensitizing Agents - pharmacology | Caspases - metabolism | Time Factors | Lipid Peroxidation - drug effects | Caspases - drug effects | Female | Clone Cells | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Glutathione Peroxidase - metabolism | Enzyme-Linked Immunosorbent Assay | Oxidation-Reduction | Aminolevulinic Acid - pharmacology | Epithelial Cells - pathology | Cardiolipins - metabolism | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria - pathology | Blotting, Western | Cytochrome c Group - metabolism | Breast Neoplasms - pathology | Cell Line, Tumor | Enzyme Activation
Lipid peroxidation | Photodynamic therapy | Cardiolipin | Aminolevulinic acid | Apoptosis | LIPID-PEROXIDATION | CHOLESTEROL | photodynamic therapy | BIOCHEMISTRY & MOLECULAR BIOLOGY | MEMBRANES | apoptosis | DEATH | RELEASE | HYDROPEROXIDE GLUTATHIONE-PEROXIDASE | CHROMATOGRAPHY | cardiolipin | lipid peroxidation | CYTOCHROME-C | BIOPHYSICS | aminolevulinic acid | SINGLET OXYGEN | Mitochondria - enzymology | Apoptosis - drug effects | Epithelial Cells - drug effects | Humans | Caspases - analysis | Chromatography, High Pressure Liquid | Photochemotherapy | Photosensitizing Agents - pharmacology | Caspases - metabolism | Time Factors | Lipid Peroxidation - drug effects | Caspases - drug effects | Female | Clone Cells | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Glutathione Peroxidase - metabolism | Enzyme-Linked Immunosorbent Assay | Oxidation-Reduction | Aminolevulinic Acid - pharmacology | Epithelial Cells - pathology | Cardiolipins - metabolism | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria - pathology | Blotting, Western | Cytochrome c Group - metabolism | Breast Neoplasms - pathology | Cell Line, Tumor | Enzyme Activation
Journal Article