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Lancet, The, ISSN 0140-6736, 2010, Volume 376, Issue 9757, pp. 2000 - 2008
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, pp. e52695 - e52695
Introduction: Older patients with acute myeloid leukemia (AML) experience short survival despite intensive chemotherapy. Azacitidine has promising activity in... 
CONVENTIONAL CARE REGIMENS | PROGNOSTIC IMPACT | IDH2 MUTATIONS | 5-AZACYTIDINE | RECOMMENDATIONS | MULTIDISCIPLINARY SCIENCES | TET2 | RISK MYELODYSPLASTIC SYNDROMES | DNMT3A MUTATIONS | INDUCTION | CHRONIC MYELOMONOCYTIC LEUKEMIA | Humans | Middle Aged | Induction Chemotherapy | Male | Treatment Outcome | Consolidation Chemotherapy | Cytarabine - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - toxicity | Feasibility Studies | Leukemia, Myeloid, Acute - mortality | Maximum Tolerated Dose | Pilot Projects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Survival Analysis | Leukemia, Myeloid, Acute - drug therapy | Female | Aged | Daunorubicin - administration & dosage | Azacitidine - administration & dosage | Anthracyclines | Chemotherapy | Analysis | Oncology, Experimental | Clinical trials | Aged patients | Research | Standards | Cancer | Toxicity | Leukemia | Brain cancer | Oncology | Cardiovascular disease | Kinases | Randomization | Cytarabine | Daunorubicin | Consolidation | Safety engineering | DNA methylation | Bone marrow | Remission | Heart diseases | Drug dosages | Deoxyribonucleic acid--DNA | Medical research | Hematology | Myeloid leukemia | Feasibility studies | Patients | Survival | Constraining | White blood cells | Medicine | Medical prognosis | Mutation | Acute myeloid leukemia | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 05/2012, Volume 366, Issue 21, pp. 2031 - 2035
Journal Article
Journal Article
Scientific reports, ISSN 2045-2322, 06/2019, Volume 9, Issue 1, pp. 8262 - 16
Post-translational modifications of core histones participate in controlling the expression of genes. Methylation of lysine 4 of histone H3 (H3K4), together... 
Cell proliferation | Osteoprogenitor cells | Chromatin | Mitosis | Gene regulation | Gene expression | Hemopoiesis | Ataxin | Lysine | Cell cycle | Histones | Post-translation | Bone marrow | DNA methylation | Catalysis | Acetylation | Histone H3
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, p. e0125783
The adapter protein metastasis suppressor 1 (MTSS1) is implicated as a tumor suppressor or tumor promoter, depending on the type of solid cancer. Here, we... 
MIM | HEPATOCELLULAR-CARCINOMA | METASTASIS | GENE | COLORECTAL-CANCER | MULTIDISCIPLINARY SCIENCES | MUTATIONS | EXPRESSION | CONTRIBUTES | REMISSION | MIM/MTSS1 | Gene Expression | Tumor Suppressor Proteins - metabolism | Prognosis | Humans | Leukemia, Myeloid, Acute - metabolism | Gene Expression Regulation, Leukemic - drug effects | Gene Expression Profiling | Neoplasm Proteins - metabolism | Leukemia, Myeloid, Acute - mortality | RUNX1 Translocation Partner 1 Protein | fms-Like Tyrosine Kinase 3 - genetics | Oncogene Proteins, Fusion - genetics | Tumor Suppressor Proteins - genetics | Chromosome Aberrations | Cell Line, Tumor | Microfilament Proteins - metabolism | Protein Kinase Inhibitors - pharmacology | Neoplasm Proteins - genetics | Core Binding Factor Alpha 2 Subunit - genetics | Microfilament Proteins - genetics | Karyotype | Cluster Analysis | Leukemia, Myeloid, Acute - genetics | Physiological aspects | Tumor suppressor genes | Research | Gene mutations | Protein kinase C | Pathogenesis | Leukemia | Colorectal cancer | Oncology | mRNA | Metastasis | Metastases | Ovarian cancer | Liver cancer | Fusion protein | Hematology | Myeloid leukemia | Adapters | Pharmacology | Gene expression | Patients | Medicine | Signaling | AML1 protein | Derepression | MicroRNAs | Medical prognosis | Cell lines | Stem cells | Mutation | Prostate cancer | Acute myeloid leukemia | Retinoic acid | Health informatics | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, p. e40853
Journal Article
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 10/2016, Volume 6, Issue 1, p. 35454
STAT5 is an essential transcription factor in hematopoiesis, which is activated through tyrosine phosphorylation in response to cytokine stimulation.... 
SH2 DOMAIN | MAINTENANCE | PROTEIN | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ACUTE LYMPHOBLASTIC-LEUKEMIA | TRANSCRIPTION | FORCE-FIELD | MUTATIONS | SIMULATIONS | POTENTIALS | Tyrosine | Phosphorylation | Molecular modelling | Phosphotyrosine | Homology | Stat5 protein | Lymphatic leukemia | Hydrophobicity | Drug development | Dimerization | Hemopoiesis
Journal Article
Medicine (United States), ISSN 0025-7974, 05/2016, Volume 95, Issue 20, p. e3355
Journal Article