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1. Full Text IL‐10 and IL‐10 receptor defects in humans
by Glocker, Erik‐Oliver and Kotlarz, Daniel and Klein, Christoph and Shah, Neil and Grimbacher, Bodo
Annals of the New York Academy of Sciences, ISSN 0077-8923, 12/2011, Volume 1246, Issue 1, pp. 102 - 107
Inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative colitis (UC), is chronic in nature and is characterized by abdominal pain,... 
mutation | IL‐10 | IL‐10 receptor | inflammatory bowel disease | STAT3 | Inflammatory bowel disease | Mutation | IL-10 receptor | IL-10 | X-LINKED SYNDROME | CROHNS-DISEASE | MULTIDISCIPLINARY SCIENCES | INTERLEUKIN-10 RECEPTOR | ULCERATIVE-COLITIS | IMMUNE DYSREGULATION | INFLAMMATORY-BOWEL-DISEASE | EPITHELIAL-CELLS | GENETICS & HEREDITY | REGULATORY T-CELLS | HOST-DEFENSE | POLYENDOCRINOPATHY | Crohn Disease - genetics | Signal Transduction | Colitis, Ulcerative - metabolism | Humans | Inflammatory Bowel Diseases - immunology | Colitis, Ulcerative - genetics | Crohn Disease - metabolism | Colitis, Ulcerative - immunology | Crohn Disease - immunology | Inflammatory Bowel Diseases - metabolism | Interleukins - metabolism | Interleukins - genetics | Receptors, Interleukin-10 - metabolism | Phenotype | Interleukin-10 - genetics | Interleukins - immunology | Inflammatory Bowel Diseases - genetics | Interleukin-10 - metabolism | Receptors, Interleukin-10 - genetics | Medical colleges | Bacteria | Transplantation | Crohn's disease | Hematopoietic stem cells | Ulcerative colitis | Immune systems | Human | Mutations | Crohn's Disease | Receptors | Stem cells | Disorders
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2. Full Text Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor
by Glocker, Erik-Oliver and Kotlarz, Daniel and Boztug, Kaan and Gertz, E. Michael and Schäffer, Alejandro A and Noyan, Fatih and Perro, Mario and Diestelhorst, Jana and Allroth, Anna and Murugan, Dhaarini and Hätscher, Nadine and Pfeifer, Dietmar and Sykora, Karl-Walter and Sauer, Martin and Kreipe, Hans and Lacher, Martin and Nustede, Rainer and Woellner, Cristina and Baumann, Ulrich and Salzer, Ulrich and Koletzko, Sibylle and Shah, Neil and Segal, Anthony W and Sauerbrey, Axel and Buderus, Stephan and Snapper, Scott B and Grimbacher, Bodo and Klein, Christoph
The New England Journal of Medicine, ISSN 0028-4793, 11/2009, Volume 361, Issue 21, pp. 2033 - 2045
Genetic analyses showed that mutations affecting the interleukin-10 receptor are associated with early-onset colitis. Further molecular analyses showed that... 
INTESTINAL INFLAMMATION | MEDICINE, GENERAL & INTERNAL | CYTOKINE PRODUCTION | CROHNS-DISEASE | CRYSTAL-STRUCTURE | ULCERATIVE-COLITIS | AUTOSOMAL RECESSIVE ENTEROCOLITIS | SEQUENCE VARIANTS | LOCI CONTRIBUTE | IL-10 | GENOME-WIDE ASSOCIATION | Tumor Necrosis Factor-alpha - metabolism | Humans | Infant | Male | Mutation, Missense | Remission Induction | Sequence Analysis, DNA | Stem Cell Transplantation | Interleukin-10 Receptor alpha Subunit - chemistry | Interleukin-10 Receptor beta Subunit - chemistry | Interleukin-10 Receptor alpha Subunit - genetics | Pedigree | Age of Onset | Inflammatory Bowel Diseases - genetics | Interleukin-10 - metabolism | Female | Chromosomes, Human, Pair 11 | Polymorphism, Single Nucleotide | Interleukin-10 Receptor beta Subunit - genetics | Chromosomes, Human, Pair 21 | Inflammatory Bowel Diseases - therapy | Genetic Linkage | Intestines | Inflammatory bowel diseases | Care and treatment | Interleukin-10 | Gene mutations | Analysis | Physiological aspects | Genetic aspects | Diagnosis | Health aspects | Inflammatory bowel disease | Proteins | Studies | Ostomy | Cytokines | Lymphocytes | Ear diseases | Immune system
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3. Full Text Impaired IL-12- and IL-23-Mediated Immunity Due to IL-12Rβ1 Deficiency in Iranian Patients with Mendelian Susceptibility to Mycobacterial Disease
by Nekooie-Marnany, Nioosha and Deswarte, Caroline and Ostadi, Vajiheh and Bagherpour, Bahram and Taleby, Elaheh and Ganjalikhani-Hakemi, Mazdak and Le Voyer, Tom and Rahimi, Hamid and Rosain, Jérémie and Pourmoghadas, Zahra and Sheikhbahaei, Saba and Khoshnevisan, Razieh and Petersheim, Daniel and Kotlarz, Daniel and Klein, Christoph and Boisson-Dupuis, Stéphanie and Casanova, Jean-Laurent and Bustamante, Jacinta and Sherkat, Roya
Journal of Clinical Immunology, ISSN 0271-9142, 10/2018, Volume 38, Issue 7, pp. 787 - 793
Inborn errors of IFN-γ-mediated immunity underlie Mendelian Susceptibility to Mycobacterial Disease (MSMD), which is characterized by an increased... 
(BCG)-osis | IL-12 | interferon | Mendelian susceptibility to mycobacterial disease | Bacillus Calmette–Guérin vaccination | Osteomyelitis | γ-Interferon | Interleukin 1 | BCG | Interleukin 12 | Interleukin 23 | Lymphocytes T | Mutation | Bacillus Calmette-Guérin vaccination
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4. Full Text Myb-like, SWIRM, and MPN domains 1 (MYSM1) deficiency: Genotoxic stress-associated bone marrow failure and developmental aberrations
by Bahrami, Ehsan, MSc and Witzel, Maximilian, MD and Racek, Tomas, PhD and Puchałka, Jacek, PhD and Hollizeck, Sebastian, MSc and Greif-Kohistani, Naschla, MD and Kotlarz, Daniel, MD, PhD and Horny, Hans-Peter, MD and Feederle, Regina, PhD and Schmidt, Heinrich, MD and Sherkat, Roya, MD and Steinemann, Doris, PhD and Göhring, Gudrun, MD and Schlegelbeger, Brigitte, MD and Albert, Michael H., MD and Al-Herz, Waleed, MD and Klein, Christoph, MD, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2017, Volume 140, Issue 4, pp. 1112 - 1119
Background Myb-like, SWIRM, and MPN domains 1 (MYSM1) is a transcriptional regulator mediating histone deubiquitination. Its role in human immunity and... 
Allergy and Immunology | stem cells | hematopoiesis | rare disease | Immunodeficiency | transplantation | P53 PROTEIN | PHOSPHORYLATION | DOUBLE-STRAND BREAKS | IMMUNOLOGY | LYMPHOCYTE DIFFERENTIATION | REFERENCE VALUES | UV-RADIATION | ALLERGY | STEM-CELL MAINTENANCE | EPIGENETIC REGULATION | HISTONE H2A DEUBIQUITINASE | Genome-Wide Association Study | Humans | Cells, Cultured | Hematopoietic Stem Cell Transplantation | Genotype | DNA Damage - immunology | DNA Repair - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Ubiquitination | Hematopoiesis | Pedigree | Bone Marrow Diseases - immunology | Developmental Disabilities - immunology | Consanguinity | p38 Mitogen-Activated Protein Kinases - metabolism | Histones - metabolism | Immunologic Deficiency Syndromes - immunology | Sequence Deletion - genetics | Monoclonal antibodies | Codon | Analysis | Genomics | Transplantation | B cells | Nucleotide sequencing | Hematopoietic stem cells | Risk factors | DNA sequencing | Cataracts | Reactive oxygen species | Phosphorylation | p38 Protein | Transplants & implants | Transcription | Nonsense mutation | DNA damage | Genotoxicity | Stem cell transplantation | Genomes | Cognition | Kinases | Homozygosity | Phosphatase | Immunity | Blood | Gene sequencing | Proteins | Penicillin | Bone marrow | Deoxyribonucleic acid--DNA | Siblings | Stresses | Cell survival | U.V. radiation | Anemia | Stop codon | Patients | Survival | Stress | Hemopoiesis | Studies | Ultraviolet radiation | Lymphocytes B | Biopsy | Stem cells | Epigenetics | Bone | Mutation | Aberration | Leukocytes (granulocytic) | Gene mapping | Apoptosis
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5. Full Text LAMTOR2 Is Dispensable for T Cell Receptor-Mediated Signaling of Thymocytes but Controls Medullary Thymic Epithelial Cells
by Wendeler, Lina and Huber, Lukas A and Klein, Christoph and Kotlarz, Daniel
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 1122 - 1122
Abstract Human LAMTOR2 deficiency is characterized by severe congenital neutropenia, growth failure, partial albinism, as well as B and T cell deficiencies... 
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6. Full Text Human TGF-β1 deficiency causes severe inflammatory bowel disease and encephalopathy
by Kotlarz, Daniel and Marquardt, Benjamin and Barøy, Tuva and Lee, Way S and Konnikova, Liza and Hollizeck, Sebastian and Magg, Thomas and Lehle, Anna S and Walz, Christoph and Borggraefe, Ingo and Hauck, Fabian and Bufler, Philip and Conca, Raffaele and Wall, Sarah M and Schumacher, Eva M and Misceo, Doriana and Frengen, Eirik and Bentsen, Beint S and Uhlig, Holm H and Hopfner, Karl-Peter and Muise, Aleixo M and Snapper, Scott B and Strømme, Petter and Klein, Christoph
Nature Genetics, ISSN 1061-4036, 03/2018, Volume 50, Issue 3, pp. 344 - 348
Transforming growth factor (TGF)-β1 (encoded by TGFB1) is the prototypic member of the TGF-β family of 33 proteins that orchestrate embryogenesis, development... 
Severity of Illness Index | DNA Mutational Analysis | Pedigree | Brain Diseases - complications | Humans | Inflammatory Bowel Diseases - pathology | Brain Diseases - genetics | Inflammatory Bowel Diseases - genetics | Female | Male | Transforming Growth Factor beta1 - genetics | Inflammatory Bowel Diseases - complications | Brain | Inflammatory bowel diseases | Nuclear magnetic resonance--NMR | Peptides | Epilepsy | Central nervous system | Homeostasis | Genomes | Leukoencephalopathy | Immunity | Proteins | Atrophy | Embryogenesis | Neurodegeneration | Intestine | Encephalopathy | Bioinformatics | Growth factors | Age | Cytomegalovirus | Transforming growth factor-b1 | Secretion | Bioavailability | Patients | Crohns disease | Embryonic growth stage | Inflammatory bowel disease | Ostomy | Mutation | Alzheimers disease
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7. Full Text Human TGF-[beta]1 deficiency causes severe inflammatory bowel disease and encephalopathy
by Kotlarz, Daniel and Marquardt, Benjamin and Baroy, Tuva and Lee, Way S and Konnikova, Liza and Hollizeck, Sebastian and Magg, Thomas
Nature Genetics, ISSN 1061-4036, 03/2018, Volume 50, Issue 3, p. 344
Transforming growth factor (TGF)-[beta]1 (encoded by TGFB1) is the prototypic member of the TGF-[beta] family of 33 proteins that orchestrate embryogenesis,... 
Inflammatory bowel diseases | Encephalopathy | Central nervous system | Research | Transforming growth factors | Health aspects | Risk factors
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8. Full Text Alternative Splicing Rescues Loss of Common Gamma Chain Function and Results in IL-21R-like Deficiency
by Illig, David and Navratil, Marta and Kelečić, Jadranka and Conca, Raffaele and Hojsak, Iva and Jadrešin, Oleg and Ćorić, Marijana and Vuković, Jurica and Rohlfs, Meino and Hollizeck, Sebastian and Bohne, Jens and Klein, Christoph and Kotlarz, Daniel
Journal of Clinical Immunology, ISSN 0271-9142, 2/2019, Volume 39, Issue 2, pp. 207 - 215
Inborn errors in interleukin 2 receptor, gamma (IL2RG) perturb signaling of the common gamma chain family cytokines and cause severe combined immunodeficiency... 
Medical Microbiology | Biomedicine | Immunology | Infectious Diseases | Internal Medicine | immunodeficiency | splicing | IL-21R | SCID | IL-2R | INTERLEUKIN-2 | CELLS | SEVERE COMBINED IMMUNODEFICIENCY | COMPLEX | RECEPTOR | IL-2 | IMMUNOLOGY | RESPONSES | REVERSION | PLEIOTROPY | MUTATIONS | Chain stores | Killer cells | Interleukins | Analysis | Immunodeficiency | Alternative splicing | Interleukin 2 receptors | Flow cytometry | Phosphorylation | Severe combined immunodeficiency | Cytokines | Cholangitis | Stat3 protein | Diarrhea | Stat5 protein | Gene deletion | Interleukin 15 | Ribonucleic acid--RNA | Defects | Cryptosporidiosis | Interleukin 7 | Interleukin 4 | Clonal deletion | Lymphocytes B | Interleukin 2 | Isoforms | Stat6 protein | Interleukin 21 | Natural killer cells
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9. Full Text Human RIPK1 deficiency causes combined immunodeficiency and inflammatory bowel diseases
by Li, Yue and Führer, Marita and Bahrami, Ehsan and Socha, Piotr and Klaudel-Dreszler, Maja and Bouzidi, Amira and Liu, Yanshan and Lehle, Anna S and Magg, Thomas and Hollizeck, Sebastian and Rohlfs, Meino and Conca, Raffaele and Field, Michael and Warner, Neil and Mordechai, Slae and Shteyer, Eyal and Turner, Dan and Boukari, Rachida and Belbouab, Reda and Walz, Christoph and Gaidt, Moritz M and Hornung, Veit and Baumann, Bernd and Pannicke, Ulrich and Idrissi, Eman Al and Alghamdi, Hamza Ali and Sepulveda, Fernando E and Gil, Marine and De Saint Basile, Geneviève and Hönig, Manfred and Koletzko, Sibylle and Muise, Aleixo M and Snapper, Scott B and Schwarz, Klaus and Klein, Christoph and Kotlarz, Daniel
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2019, Volume 116, Issue 3, pp. 970 - 975
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is a critical regulator of cell death and inflammation, but its relevance for human disease... 
Rare diseases | Inflammatory bowel diseases | Primary immunodeficiency | rare diseases | APOPTOSIS | HOMEOSTASIS | NECROPTOSIS | inflammatory bowel diseases | AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME | MULTIDISCIPLINARY SCIENCES | KINASE | primary immunodeficiency | DEATH | MUTATIONS | Humans | Inflammatory Bowel Diseases - immunology | NF-kappa B - immunology | Male | Cell Differentiation - genetics | Intestinal Mucosa - immunology | Inflammatory Bowel Diseases - pathology | HEK293 Cells | Inflammatory Bowel Diseases - genetics | Female | B-Lymphocytes - pathology | Severe Combined Immunodeficiency - pathology | T-Lymphocytes - pathology | Receptor-Interacting Protein Serine-Threonine Kinases - immunology | Immunity, Mucosal - genetics | HCT116 Cells | Epithelial Cells - pathology | Severe Combined Immunodeficiency - immunology | Cell Differentiation - immunology | Severe Combined Immunodeficiency - genetics | B-Lymphocytes - immunology | NF-kappa B - genetics | Epithelial Cells - immunology | T-Lymphocytes - immunology | Receptor-Interacting Protein Serine-Threonine Kinases - deficiency | Mutation | Intestinal Mucosa - pathology | Deficiency diseases | Complications and side effects | Threonine | Immunodeficiency | Causes of | Physiological aspects | Genetic aspects | Protein kinases | Tumor necrosis factor receptors | Enzymes | NF-κB protein | Pathogenesis | Epithelial cells | Homeostasis | Kinases | Patients | Inflammatory bowel disease | Proteins | Lymphocytes B | Intestine | Cell death | Protein kinase | Immune system | Life Sciences | Immunology | Biological Sciences
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10. Full Text LamtoR2 (p14) controls B cell differentiation by orchestrating endosomal BCR trafficking
by Łyszkiewicz, Marcin and Kotlarz, Daniel and Ziȩtara, Natalia and Brandes, Gudrun and Diestelhorst, Jana and Glage, Silke and Hobeika, Elias and Reth, Michael and Huber, Lukas A and Krueger, Andreas and Klein, Christoph
Frontiers in Immunology, ISSN 1664-3224, 2019, Volume 10, p. 497
B-cell development and function depend on stage-specific signaling through the B-cell antigen receptor (BCR). Signaling and intracellular trafficking of the... 
Signal transduction | P14 | LAMTOR2 | B cells | B-cell antigen receptor | Trafficking | RECOMBINATION | signal transduction | KINASE | TRANSCRIPTION | IMMUNOLOGY | SIGNAL-TRANSDUCTION | p14 | INTERNALIZATION | SCAFFOLD COMPLEX | RECEPTORS | trafficking
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11. Full Text The phenotype of human STK4 deficiency
by Abdollahpour, Hengameh and Appaswamy, Giridharan and Kotlarz, Daniel and Diestelhorst, Jana and Beier, Rita and Schäffer, Alejandro A and Gertz, E. Michael and Schambach, Axel and Kreipe, Hans H and Pfeifer, Dietmar and Engelhardt, Karin R and Rezaei, Nima and Grimbacher, Bodo and Lohrmann, Sabine and Sherkat, Roya and Klein, Christoph
Blood, ISSN 0006-4971, 04/2012, Volume 119, Issue 15, pp. 3450 - 3457
We describe a novel clinical phenotype associating T- and B-cell lymphopenia, intermittent neutropenia, and atrial septal defects in 3 members of a... 
APOPTOSIS | OXIDATIVE-STRESS | KINASE MST1 | ACTIVATION | ORGAN SIZE CONTROL | PHOSPHORYLATION | PATHWAY | CONGENITAL NEUTROPENIA | MUTATIONS | CASPASE CLEAVAGE | HEMATOLOGY | Protein-Serine-Threonine Kinases - deficiency | Immunologic Deficiency Syndromes - complications | Humans | Protein-Serine-Threonine Kinases - genetics | Child, Preschool | Male | Case-Control Studies | Neutropenia - etiology | Phenotype | DNA Mutational Analysis | Pedigree | Base Sequence | Immunologic Deficiency Syndromes - genetics | Female | Immunologic Deficiency Syndromes - blood | Consanguinity | Neutropenia - blood | Immunologic Deficiency Syndromes - immunology | Iran - epidemiology | Neutropenia - genetics | Neutropenia - immunology | Immunobiology | Phagocytes, Granulocytes, and Myelopoiesis
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12. Full Text Novel Mutations in RASGRP1 are Associated with Immunodeficiency, Immune Dysregulation, and EBV-Induced Lymphoma
by Somekh, Ido and Marquardt, Benjamin and Liu, Yanshan and Rohlfs, Meino and Hollizeck, Sebastian and Karakukcu, Musa and Unal, Ekrem and Yilmaz, Ebru and Patiroglu, Turkan and Cansever, Murat and Frizinsky, Shirly and Vishnvenska-Dai, Vicktoria and Rechavi, Erez and Stauber, Tali and Simon, Amos J and Lev, Atar and Klein, Christoph and Kotlarz, Daniel and Somech, Raz
Journal of Clinical Immunology, ISSN 0271-9142, 8/2018, Volume 38, Issue 6, pp. 699 - 710
RAS guanyl-releasing protein 1 (RASGRP1) deficiency has recently been shown to cause a primary immunodeficiency (PID) characterized by CD4+ T cell lymphopenia... 
Autoimmunity | T cell development | Medical Microbiology | Biomedicine | Immunology | EBV | Infectious Diseases | Internal Medicine | lymphoproliferation | PID | RASGRP1 | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVATION | HOMEOSTASIS | RAS | IMMUNOLOGY | LINEAGE COMMITMENT | RASGRP1-DEFICIENT MICE | DISEASES | NON-HODGKIN-LYMPHOMA | DIFFERENTIATION | T-CELL DEVELOPMENT | Immunodeficiency | Lymphomas | Genetic aspects | Transplantation | T cells | Hematopoietic stem cells | Stem cell transplantation | Extracellular signal-regulated kinase | Immunoblotting | T cell receptors | Ras protein | Protein deficiency | Patients | Genetic screening | Hemopoiesis | CD4 antigen | T-cell receptor | Lymphocytes B | Lymphopenia | Lymphocytes | Mutation | Autoimmune diseases | Guanosinetriphosphatase | B-cell lymphoma
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13. Full Text Human IL-21 and IL-21R deficiencies: Two novel entities of primary immunodeficiency
by Kotlarz, Daniel and Ziętara, Natalia and Milner, Joshua D and Klein, Christoph
Current Opinion in Pediatrics, ISSN 1040-8703, 2014, Volume 26, Issue 6, pp. 704 - 712
Purpose of reviewThis review highlights the recent identification of human interleukin-21 (IL-21) and interleukin-21 receptor (IL-21R) deficiencies as novel... 
Cryptosporidiosis | Inflammatory bowel disease | Interleukin-21 | Hematopoietic stem cell transplantation | Primary immunodeficiency | ACTIVATION | interleukin-21 | inflammatory bowel disease | CD8(+) T-CELLS | B-CELLS | HUMAN NAIVE | NK CELLS | INTERLEUKIN-21 RECEPTOR | hematopoietic stem cell transplantation | primary immunodeficiency | COMMON GAMMA-CHAIN | PEDIATRICS | AUTOCRINE REGULATION | DIFFERENTIATION | cryptosporidiosis | EXPRESSION | Interleukins - genetics | Receptors, Interleukin-21 - deficiency | Humans | Immunologic Deficiency Syndromes - genetics | Interleukins - deficiency | Receptors, Interleukin-21 - genetics | Child
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14. Full Text Loss of Interleukin-10 Signaling and Infantile Inflammatory Bowel Disease: Implications for Diagnosis and Therapy
by Kotlarz, Daniel and Beier, Rita and Murugan, Dhaarini and Diestelhorst, Jana and Jensen, Ole and Boztug, Kaan and Pfeifer, Dietmar and Kreipe, Hans and Pfister, Eva–Doreen and Baumann, Ulrich and Puchalka, Jacek and Bohne, Jens and Egritas, Odul and Dalgic, Buket and Kolho, Kaija–Leena and Sauerbrey, Axel and Buderus, Stephan and Güngör, Tayfun and Enninger, Axel and Koda, Yu Kar Ling and Guariso, Graziella and Weiss, Batia and Corbacioglu, Selim and Socha, Piotr and Uslu, Nuray and Metin, Ayse and Wahbeh, Ghassan T and Husain, Khalid and Ramadan, Dina and Al–Herz, Waleed and Grimbacher, Bodo and Sauer, Martin and Sykora, Karl–Walter and Koletzko, Sibylle and Klein, Christoph
Gastroenterology, ISSN 0016-5085, 2012, Volume 143, Issue 2, pp. 347 - 355
Background & Aims Homozygous loss of function mutations in interleukin-10 ( IL10 ) and interleukin-10 receptors ( IL10R ) cause severe infantile (very early... 
Gastroenterology and Hepatology | Genetic Defect | Children | Intestinal Inflammation | Immunodeficiency | COMPLETE REMISSION | BONE-MARROW-TRANSPLANTATION | RECEPTOR | PATHOGENESIS | REFRACTORY CROHNS-DISEASE | COLITIS | NON-HODGKINS-LYMPHOMA | LEUKEMIA | STEM-CELL TRANSPLANTATION | GASTROENTEROLOGY & HEPATOLOGY | GENOME-WIDE ASSOCIATION | Interleukin-10 - deficiency | Enzyme-Linked Immunosorbent Assay | Interleukin-10 Receptor beta Subunit - deficiency | Humans | Inflammatory Bowel Diseases - diagnosis | Hematopoietic Stem Cell Transplantation | Infant | Male | Treatment Outcome | Genetic Markers | Interleukin-10 Receptor alpha Subunit - deficiency | Sequence Analysis, DNA | Blotting, Western | Interleukin-10 Receptor alpha Subunit - genetics | Interleukin-10 - genetics | Inflammatory Bowel Diseases - genetics | Inflammatory Bowel Diseases - surgery | Female | Interleukin-10 Receptor beta Subunit - genetics | Mutation | Cohort Studies | Medical colleges | Interleukins | Gastrointestinal diseases | Stem cells | Transplantation | Health aspects | Mitogens | Hematopoietic stem cells | Tumors
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