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alpha (2) 2
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Annals of the Rheumatic Diseases, ISSN 0003-4967, 05/2018, Volume 77, Issue 5, pp. e26 - E26
In order to further experimentally investigate the actual role of hypertension in OA onset and development, Chan and colleagues describe in a yet unpublished... 
arterial hypertension | knee osteoarthritis | osteoarthritis | KNEE OSTEOARTHRITIS | MODEL | RHEUMATOLOGY | Rats | Phenotype | Animals | Meniscus | Eplerenone | Osteoarthritis | Heart failure | Hypertension | Knee | Genotype & phenotype | Phenotypes | Rodents | Arthritis | Metabolic syndrome | Investigations | Index Medicus
Journal Article
Arthritis Research and Therapy, ISSN 1478-6354, 01/2008, Volume 10, Issue 1, pp. R6 - R6
Background Rosiglitazone and pioglitazone are high-affinity peroxisome proliferator-activated receptor (PPAR)-gamma agonists with potent anti-diabetic... 
RHEUMATOID-ARTHRITIS | COLLAGEN-INDUCED ARTHRITIS | ADJUVANT-INDUCED ARTHRITIS | NUCLEAR RECEPTORS | PPAR-GAMMA | JOINT DESTRUCTION | NECROSIS-FACTOR-ALPHA | RHEUMATOLOGY | PROLIFERATOR-ACTIVATED-RECEPTOR | LEWIS RATS | ENDOTHELIAL GROWTH-FACTOR | Hindlimb | Rats, Inbred Lew | Male | RNA, Messenger - metabolism | Thiazolidinediones - administration & dosage | Bone Remodeling - drug effects | Fever - physiopathology | Bone and Bones - drug effects | Incidence | Arthritis, Experimental - pathology | Dose-Response Relationship, Drug | Adipose Tissue - metabolism | Hypoglycemic Agents - administration & dosage | Arthritis, Experimental - epidemiology | Adiponectin - genetics | Bone and Bones - metabolism | Fibroblast Growth Factor 2 - metabolism | Anti-Inflammatory Agents - administration & dosage | Weight Gain - drug effects | Thiazolidinediones - pharmacology | PPAR gamma - genetics | Biomarkers - metabolism | Bone Resorption - etiology | Arthritis, Experimental - physiopathology | Cytokines - metabolism | Anti-Inflammatory Agents - pharmacology | Adipose Tissue - pathology | Rats | Arthritis, Experimental - complications | Synovial Membrane - metabolism | Hypoglycemic Agents - pharmacology | Synovitis - pathology | Bone Resorption - prevention & control | Cartilage, Articular - pathology | Bone Density - drug effects | Animals | Cartilage, Articular - drug effects | Adipose Tissue - drug effects | Prevention | Polymerase chain reaction | Usage | Arthritis | Dosage and administration | Research | Drug therapy | Thiazolidinediones | Methods | Index Medicus | Life Sciences | Human health and pathology | Pharmacology | Rhumatology and musculoskeletal system | Pharmaceutical sciences
Journal Article
Journal Article
Arthritis Research & Therapy, ISSN 1478-6354, 12/2008, Volume 10, p. R141
Interleukin-6 (IL-6) is thought to play a pathogenic role in rheumatoid arthritis and synovium is a major source of IL-6 release. We investigated the ability... 
Rheumatoid arthritis | Physiological aspects | Cytokine receptors | Development and progression | Retinoids | Research | Interleukin-6
Journal Article
Arthritis Research & Therapy, ISSN 1478-6354, 2005, Volume 7, Issue 6, pp. R1325 - R1337
Microsomal prostaglandin E synthase (mPGES)-1 is a newly identified inducible enzyme of the arachidonic acid cascade with a key function in prostaglandin... 
Journal Article
Arthritis Research and Therapy, ISSN 1478-6354, 2005, Volume 7, Issue 6, pp. R1325 - R1337
Microsomal prostaglandin E synthase (mPGES)-1 is a newly identified inducible enzyme of the arachidonic acid cascade with a key function in prostaglandin (PG)E... 
Life Sciences | Human health and pathology | Biochemistry, Molecular Biology | Genomics | Rhumatology and musculoskeletal system
Journal Article
Journal Article
Journal Article
Arthritis and Rheumatism, ISSN 0004-3591, 12/2013, Volume 65, Issue 12, p. 3084
  Objective To investigate the effect of pioglitazone on inflammation-induced bone loss and changes in bone microarchitecture in rats with adjuvant-induced... 
Cytokines | Rodents | Bone density | Arthritis
Journal Article
Journal Article
Arthritis and Rheumatism, ISSN 0004-3591, 03/2005, Volume 52, Issue 3, pp. 759 - 769
Objective. To study the potency of 2 peroxisome proliferator-activated receptor gamma (PPAR gamma) agonists, 15-deoxy-Delta(12,14)-prostagiandin J(2)... 
RHEUMATOID-ARTHRITIS | COLLAGEN-INDUCED ARTHRITIS | PPAR-GAMMA LIGANDS | ACCESSORY PROTEIN | HUMAN CHONDROCYTES | DELTA | GENE-EXPRESSION | SMOOTH-MUSCLE-CELLS | IL-1 RECEPTOR | KAPPA-B | RHEUMATOLOGY
Journal Article
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