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Neuro-Oncology, ISSN 1522-8517, 11/2019, Volume 21, Issue Supplement_6, pp. vi71 - vi72
Abstract Temozolomide (TMZ) is the standard chemotherapy for malignant gliomas (MG), and resistance to this drug is mediated by the DNA repair protein... 
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 2122 - 2122
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14_Supplement, pp. 2122 - 2122
Glioblastoma multiforme (GBM) is the most common form of malignant brain cancer in adults. The prognosis of affected patients is poor and median survival is... 
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 4032 - 4032
Journal Article
Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. 31 - 31
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2019, Volume 21, Issue Supplement_6, pp. vi40 - vi40
Abstract Comprehensive analysis of the TCGA Glioblastoma database has identified 3 prognostically relevant subgroups (Proneural, Classical and Mesenchymal).... 
Journal Article
Journal of Immunology, ISSN 0022-1767, 08/2004, Volume 173, Issue 3, pp. 2011 - 2022
The cyclooxygenase 2 (COX-2) inhibitor celecoxib (also called celebrex), approved,for the treatment of colon carcinogenesis, rheumatoid arthritis, and other... 
INDUCED APOPTOSIS | CHEMOPREVENTIVE ACTIVITY | CYCLIN D1 EXPRESSION | PROSTATE-CANCER CELLS | NECROSIS-FACTOR-ALPHA | INDUCIBLE PHOSPHORYLATION | IMMUNOLOGY | TRANSCRIPTION FACTOR | ANTIINFLAMMATORY DRUGS | CYCLO-OXYGENASE-2 INHIBITOR | ADENOMATOUS POLYPOSIS | Tumor Necrosis Factor-alpha - metabolism | Okadaic Acid - pharmacology | Tetradecanoylphorbol Acetate - pharmacology | Humans | Transcription Factor RelA | Lung Neoplasms - pathology | NF-kappa B - metabolism | Neoplasm Proteins - antagonists & inhibitors | Cell Line, Tumor - drug effects | I-kappa B Proteins - metabolism | Neoplasm Proteins - metabolism | Promoter Regions, Genetic - drug effects | TNF Receptor-Associated Factor 1 | TNF Receptor-Associated Factor 2 | Cyclin D1 - antagonists & inhibitors | Carcinogens - pharmacology | Protein Processing, Post-Translational - drug effects | Receptors, Tumor Necrosis Factor - antagonists & inhibitors | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Phosphorylation - drug effects | Cell Line, Tumor - metabolism | Genes, Reporter | Protein-Serine-Threonine Kinases - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | NF-KappaB Inhibitor alpha | NF-kappa B - antagonists & inhibitors | Lung Neoplasms - enzymology | Pyrazoles | Celecoxib | Enzyme Activation - drug effects | I-kappa B Kinase | Sulfonamides - pharmacology | Cyclooxygenase Inhibitors - pharmacology | Interleukin-1 - pharmacology | Proto-Oncogene Proteins c-akt | MAP Kinase Signaling System - drug effects | Lipopolysaccharides - pharmacology | Matrix Metalloproteinase Inhibitors | Carcinoma, Non-Small-Cell Lung - enzymology | Proteins - antagonists & inhibitors | Tumor Necrosis Factor-alpha - antagonists & inhibitors
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 07/2016, Volume 15, Issue 7, pp. 1656 - 1668
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2003, Volume 278, Issue 41, pp. 40057 - 40066
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2014, Volume 16, Issue suppl 5, pp. v64 - v64
Glioblastoma, with aberrant activation of growth factor signaling pathways, represents a compelling disease for kinase inhibitor therapy. Despite the evidence... 
Journal Article
Stem Cells, ISSN 1066-5099, 01/2014, Volume 32, Issue 1, pp. 301 - 312
Genomic, transcriptional, and proteomic analyses of brain tumors reveal subtypes that differ in pathway activity, progression, and response to therapy.... 
C Secretase inhibitors | Glioma | Notch activation | Proneural genes | PROFILES | SUPPRESSION | CANCER STEM-CELLS | TEMOZOLOMIDE | CELL & TISSUE ENGINEERING | CELL BIOLOGY | MALIGNANT GLIOMA | BRAIN-TUMOR | GLIOBLASTOMA | ONCOLOGY | Secretase inhibitors | SIGNALING PATHWAY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GROWTH | HEMATOLOGY | EXPRESSION
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2017, Volume 19, Issue suppl_6, pp. vi64 - vi64
Activation of PIK3CA , the gene encoding phosphoinositide-(3)-kinase (PI3K) is frequently found in glioblastoma multiforme (GBM). However, single agent... 
Abstracts
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2019, Volume 37, Issue 15_suppl, pp. 2047 - 2047
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 1781 - 1781
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 2798 - 2798
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 4170 - 4170
Journal Article
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