Nephrology Dialysis Transplantation, ISSN 0931-0509, 05/2014, Volume 29, Issue suppl 3, pp. iii501 - iii515
Journal Article
2.
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An organelle-specific protein landscape identifies novel diseases and molecular mechanisms
Nature Communications, ISSN 2041-1723, 2016, Volume 7, Issue 1, p. 11491
Cellular organelles provide opportunities to relate biological mechanisms to disease. Here we use affinity proteomics, genetics and cell biology to interrogate...
NETWORK REVEALS | CELLS | COMPLEX | TANDEM AFFINITY PURIFICATION | MICROTUBULE | MULTIDISCIPLINARY SCIENCES | CILIOGENESIS | MUTATIONS | INTRAFLAGELLAR TRANSPORT | STATISTICAL-MODEL | PRIMARY CILIA | Humans | Proteins - isolation & purification | Protein Interaction Maps | Spine - abnormalities | Ciliopathies - genetics | Muscle Hypotonia - therapy | DNA Mutational Analysis | Systems Analysis | Mass Spectrometry | HEK293 Cells | Fibroblasts | Dwarfism - pathology | Proteomics - methods | Spine - pathology | Chromatography, Affinity - methods | Molecular Targeted Therapy - methods | Ciliopathies - therapy | Datasets as Topic | Muscle Hypotonia - genetics | Cilia - metabolism | Proteins - genetics | Dwarfism - genetics | Muscle Hypotonia - pathology | Protein Interaction Mapping - methods | Dwarfism - therapy | Proteins - metabolism | Biological Transport - physiology | Ciliopathies - pathology
NETWORK REVEALS | CELLS | COMPLEX | TANDEM AFFINITY PURIFICATION | MICROTUBULE | MULTIDISCIPLINARY SCIENCES | CILIOGENESIS | MUTATIONS | INTRAFLAGELLAR TRANSPORT | STATISTICAL-MODEL | PRIMARY CILIA | Humans | Proteins - isolation & purification | Protein Interaction Maps | Spine - abnormalities | Ciliopathies - genetics | Muscle Hypotonia - therapy | DNA Mutational Analysis | Systems Analysis | Mass Spectrometry | HEK293 Cells | Fibroblasts | Dwarfism - pathology | Proteomics - methods | Spine - pathology | Chromatography, Affinity - methods | Molecular Targeted Therapy - methods | Ciliopathies - therapy | Datasets as Topic | Muscle Hypotonia - genetics | Cilia - metabolism | Proteins - genetics | Dwarfism - genetics | Muscle Hypotonia - pathology | Protein Interaction Mapping - methods | Dwarfism - therapy | Proteins - metabolism | Biological Transport - physiology | Ciliopathies - pathology
Journal Article
Nephrology Dialysis Transplantation, ISSN 0931-0509, 05/2014, Volume 29, Issue suppl 3, pp. iii79 - iii89
Journal Article
PLoS One, ISSN 1932-6203, 2019, Volume 14, Issue 5, p. e0216705
The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wide range of genetic diseases collectively called...
SOLUTE-CARRIER-PROTEIN | LEBER CONGENITAL AMAUROSIS | TRANSITION ZONE | MULTIDISCIPLINARY SCIENCES | RETINAL PHOTORECEPTOR CELLS | MUTATIONS | DIFFERENTIATION | IDENTIFICATION | INTRAFLAGELLAR TRANSPORT | EXPRESSION | PRIMARY CILIUM | Proteins | Genomics | Cells | Pediatrics | Neurosciences | Animal models | Laboratories | Genes | Otolaryngology | Biochemistry | Genomes | Mammalian cells | Gene sequencing | Physiology | Life sciences | Synthetic biology | Bioinformatics | Informatics | Phenotypes | Zebrafish | Medicine | Brain research | Hospitals | Cognition & reasoning | Photoreceptors | Molecular biology | Bayesian analysis
SOLUTE-CARRIER-PROTEIN | LEBER CONGENITAL AMAUROSIS | TRANSITION ZONE | MULTIDISCIPLINARY SCIENCES | RETINAL PHOTORECEPTOR CELLS | MUTATIONS | DIFFERENTIATION | IDENTIFICATION | INTRAFLAGELLAR TRANSPORT | EXPRESSION | PRIMARY CILIUM | Proteins | Genomics | Cells | Pediatrics | Neurosciences | Animal models | Laboratories | Genes | Otolaryngology | Biochemistry | Genomes | Mammalian cells | Gene sequencing | Physiology | Life sciences | Synthetic biology | Bioinformatics | Informatics | Phenotypes | Zebrafish | Medicine | Brain research | Hospitals | Cognition & reasoning | Photoreceptors | Molecular biology | Bayesian analysis
Journal Article
Automatica, ISSN 0005-1098, 2011, Volume 47, Issue 6, pp. 1156 - 1164
DNA replication is an important process in the life of a cell. It has to be completed with extreme accuracy in a specific phase of the cell cycle, known as the...
DNA replication | Piecewise deterministic Markov process | Systems biology | Modeling | YEAST | ORIGINS | MCM PROTEINS | INITIATION | DYNAMICS | AUTOMATION & CONTROL SYSTEMS | ENGINEERING, ELECTRICAL & ELECTRONIC | Markov processes | Monte Carlo method | Models | Analysis | DNA
DNA replication | Piecewise deterministic Markov process | Systems biology | Modeling | YEAST | ORIGINS | MCM PROTEINS | INITIATION | DYNAMICS | AUTOMATION & CONTROL SYSTEMS | ENGINEERING, ELECTRICAL & ELECTRONIC | Markov processes | Monte Carlo method | Models | Analysis | DNA
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2008, Volume 105, Issue 34, pp. 12295 - 12300
DNA replication in eukaryotic cells initiates from hundreds of origins along their genomes, leading to complete duplication of genetic information before cell...
Replication origin | Yeasts | DNA replication | Experimental data | Mitosis | Cell cycle | Genomes | Stochastic models | Modeling | Hybridity | Schizosaccharomyces pombe | Fission yeast | Random gap problem | Systems biology | systems biology | random gap problem | cell cycle | MULTIDISCIPLINARY SCIENCES | CELL-SIZE | DIVISION | EGGS | ORIGINS | GENE | FIRE | SEQUENCE | fission yeast | SCHIZOSACCHAROMYCES-POMBE | Schizosaccharomyces - genetics | Genome, Fungal - genetics | Stochastic Processes | Interphase | Models, Biological | S Phase | DNA Replication | Genomics | Models | Genetic aspects | Research | Saccharomyces | DNA biosynthesis | Initiation factors | Hybrids | Cell division | Data processing | Replication | Stochasticity | Replication forks | Biological Sciences | Physical Sciences
Replication origin | Yeasts | DNA replication | Experimental data | Mitosis | Cell cycle | Genomes | Stochastic models | Modeling | Hybridity | Schizosaccharomyces pombe | Fission yeast | Random gap problem | Systems biology | systems biology | random gap problem | cell cycle | MULTIDISCIPLINARY SCIENCES | CELL-SIZE | DIVISION | EGGS | ORIGINS | GENE | FIRE | SEQUENCE | fission yeast | SCHIZOSACCHAROMYCES-POMBE | Schizosaccharomyces - genetics | Genome, Fungal - genetics | Stochastic Processes | Interphase | Models, Biological | S Phase | DNA Replication | Genomics | Models | Genetic aspects | Research | Saccharomyces | DNA biosynthesis | Initiation factors | Hybrids | Cell division | Data processing | Replication | Stochasticity | Replication forks | Biological Sciences | Physical Sciences
Journal Article
Journal of Hypertension, ISSN 0263-6352, 08/2017, Volume 35, Issue 12, pp. 2517 - 2526
OBJECTIVES:Patients with end-stage renal-disease under hemodialysis have increased cardiovascular risk and experience severe blood pressure (BP) fluctuations...
ambulatory blood pressure monitoring | blood pressure variability | hemodialysis | average real variability | DIFFERENT INDEXES | PROGNOSTIC VALUE | EUROPEAN-SOCIETY | HYPERTENSIVE PATIENTS | CONSENSUS DOCUMENT | DIALYSIS | WAVE REFLECTIONS | WORKING GROUP | ARTERIAL STIFFNESS | CARDIOVASCULAR MORTALITY | PERIPHERAL VASCULAR DISEASE | Kidney Failure, Chronic - physiopathology | Cardiovascular Diseases - etiology | Cardiovascular Diseases - physiopathology | Humans | Middle Aged | Risk Factors | Male | Blood Pressure Monitoring, Ambulatory - instrumentation | Kidney Failure, Chronic - therapy | Kidney Failure, Chronic - complications | Female | Aged | Blood Pressure - physiology | Renal Dialysis
ambulatory blood pressure monitoring | blood pressure variability | hemodialysis | average real variability | DIFFERENT INDEXES | PROGNOSTIC VALUE | EUROPEAN-SOCIETY | HYPERTENSIVE PATIENTS | CONSENSUS DOCUMENT | DIALYSIS | WAVE REFLECTIONS | WORKING GROUP | ARTERIAL STIFFNESS | CARDIOVASCULAR MORTALITY | PERIPHERAL VASCULAR DISEASE | Kidney Failure, Chronic - physiopathology | Cardiovascular Diseases - etiology | Cardiovascular Diseases - physiopathology | Humans | Middle Aged | Risk Factors | Male | Blood Pressure Monitoring, Ambulatory - instrumentation | Kidney Failure, Chronic - therapy | Kidney Failure, Chronic - complications | Female | Aged | Blood Pressure - physiology | Renal Dialysis
Journal Article
Osteoarthritis and Cartilage, ISSN 1063-4584, 2009, Volume 17, Issue 10, pp. 1283 - 1287
Summary Objective Erosive osteoarthritis (OA) (EOA) is considered an aggressive form of primary OA that is defined radiographically by intra-articular erosions...
Rheumatology | Radiography | Erosive osteoarthritis | Synovitis | Erosions | Ultrasound | Tenosynovitis | SONOGRAPHY | RHEUMATOLOGY | PSORIATIC-ARTHRITIS | BONE EROSIONS | EARLY RHEUMATOID-ARTHRITIS | DISEASE | CONVENTIONAL RADIOGRAPHY | DOPPLER ULTRASOUND | ORTHOPEDICS | Synovial Membrane - diagnostic imaging | Humans | Middle Aged | Osteoarthritis - diagnostic imaging | Synovial Membrane - pathology | Male | Osteoarthritis - physiopathology | Finger Joint - pathology | Osteophyte - diagnostic imaging | Female | Aged | Inflammation - diagnostic imaging | Finger Joint - diagnostic imaging | Ultrasonography - methods | Ultrasonography - standards | Osteoarthritis
Rheumatology | Radiography | Erosive osteoarthritis | Synovitis | Erosions | Ultrasound | Tenosynovitis | SONOGRAPHY | RHEUMATOLOGY | PSORIATIC-ARTHRITIS | BONE EROSIONS | EARLY RHEUMATOID-ARTHRITIS | DISEASE | CONVENTIONAL RADIOGRAPHY | DOPPLER ULTRASOUND | ORTHOPEDICS | Synovial Membrane - diagnostic imaging | Humans | Middle Aged | Osteoarthritis - diagnostic imaging | Synovial Membrane - pathology | Male | Osteoarthritis - physiopathology | Finger Joint - pathology | Osteophyte - diagnostic imaging | Female | Aged | Inflammation - diagnostic imaging | Finger Joint - diagnostic imaging | Ultrasonography - methods | Ultrasonography - standards | Osteoarthritis
Journal Article
Journal of Hypertension, ISSN 0263-6352, 09/2017, Volume 35, p. e144
Journal Article
Clinical Rheumatology, ISSN 0770-3198, 4/2008, Volume 27, Issue 4, pp. 511 - 513
The objective of our study was to establish whether there is an association between rheumatoid arthritis with extra-articular manifestations (exRA) and...
Anti-cyclic citrullinated antibodies | Autoantibodies | Medicine & Public Health | Extra-articular manifestations | Rheumatoid arthritis | Rheumatology | Biomarkers | ANTIBODIES | RADIOLOGICAL PROGRESSION | DIAGNOSTIC-VALUE | biomarkers | DISEASE | RHEUMATOLOGY | extra-articular manifestations | INFLIXIMAB | anti-cyclic citrullinated antibodies | autoantibodies | rheumatoid arthritis | ASSOCIATION | Pulmonary Fibrosis - diagnosis | Rheumatoid Nodule - immunology | Prognosis | Rheumatoid Nodule - diagnosis | Autoantibodies - blood | Felty Syndrome - immunology | Humans | Middle Aged | Vasculitis - etiology | Sjogren's Syndrome - immunology | Raynaud Disease - etiology | Arthritis, Rheumatoid - complications | Vasculitis - immunology | Greece - ethnology | Retrospective Studies | Pulmonary Fibrosis - etiology | Rheumatoid Nodule - etiology | Sjogren's Syndrome - etiology | Felty Syndrome - etiology | Pulmonary Fibrosis - immunology | Peptides, Cyclic - immunology | Raynaud Disease - diagnosis | Rheumatoid Factor - immunology | Serositis - diagnosis | Vasculitis - diagnosis | Serositis - etiology | Sjogren's Syndrome - diagnosis | Arthritis, Rheumatoid - ethnology | Serositis - immunology | Aged | Raynaud Disease - immunology | Arthritis, Rheumatoid - immunology | Felty Syndrome - diagnosis | Autoimmunity | Rheumatoid factor | Immunoglobulins | Peptides | Rheumatism
Anti-cyclic citrullinated antibodies | Autoantibodies | Medicine & Public Health | Extra-articular manifestations | Rheumatoid arthritis | Rheumatology | Biomarkers | ANTIBODIES | RADIOLOGICAL PROGRESSION | DIAGNOSTIC-VALUE | biomarkers | DISEASE | RHEUMATOLOGY | extra-articular manifestations | INFLIXIMAB | anti-cyclic citrullinated antibodies | autoantibodies | rheumatoid arthritis | ASSOCIATION | Pulmonary Fibrosis - diagnosis | Rheumatoid Nodule - immunology | Prognosis | Rheumatoid Nodule - diagnosis | Autoantibodies - blood | Felty Syndrome - immunology | Humans | Middle Aged | Vasculitis - etiology | Sjogren's Syndrome - immunology | Raynaud Disease - etiology | Arthritis, Rheumatoid - complications | Vasculitis - immunology | Greece - ethnology | Retrospective Studies | Pulmonary Fibrosis - etiology | Rheumatoid Nodule - etiology | Sjogren's Syndrome - etiology | Felty Syndrome - etiology | Pulmonary Fibrosis - immunology | Peptides, Cyclic - immunology | Raynaud Disease - diagnosis | Rheumatoid Factor - immunology | Serositis - diagnosis | Vasculitis - diagnosis | Serositis - etiology | Sjogren's Syndrome - diagnosis | Arthritis, Rheumatoid - ethnology | Serositis - immunology | Aged | Raynaud Disease - immunology | Arthritis, Rheumatoid - immunology | Felty Syndrome - diagnosis | Autoimmunity | Rheumatoid factor | Immunoglobulins | Peptides | Rheumatism
Journal Article
Cilia, ISSN 2046-2530, 07/2015, Volume 4, Issue 1
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 06/2009, Volume 106, Issue 23, p. 9535
Journal Article
World Journal of Emergency Surgery, ISSN 1749-7922, 08/2011, Volume 6, Issue 1, pp. 28 - 28
Gas gangrene is a necrotic infection of soft tissue associated with high mortality, often necessitating amputation in order to control the infection. Herein we...
SURGERY | EMERGENCY MEDICINE | Care and treatment | Gas gangrene | Limb salvage | Diagnosis | Research | Health aspects | Risk factors | Irrigation | Substance abuse treatment | Pain | Antibiotics | Oxygen therapy | Skin & tissue grafts | Gangrene | Emergency medical care | Hospitalization | Manuscripts | Blood
SURGERY | EMERGENCY MEDICINE | Care and treatment | Gas gangrene | Limb salvage | Diagnosis | Research | Health aspects | Risk factors | Irrigation | Substance abuse treatment | Pain | Antibiotics | Oxygen therapy | Skin & tissue grafts | Gangrene | Emergency medical care | Hospitalization | Manuscripts | Blood
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 06/2009, Volume 106, Issue 23, pp. 9535 - 9535
Journal Article
Cilia, ISSN 2046-2530, 07/2015, Volume 4, Issue 1
Journal Article
Nonlinear Analysis: Hybrid Systems, ISSN 1751-570X, 2008, Volume 2, Issue 3, pp. 786 - 802
In this paper we study the parameter identification problem for a stochastic hybrid model of the production of the antibiotic subtilin by the bacterium . We...
Randomized optimization | Biochemical networks | Subtilin production | Parameter identification | Stochastic hybrid models | MATHEMATICS, APPLIED | AUTOMATION & CONTROL SYSTEMS
Randomized optimization | Biochemical networks | Subtilin production | Parameter identification | Stochastic hybrid models | MATHEMATICS, APPLIED | AUTOMATION & CONTROL SYSTEMS
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2008, Volume 105, Issue 34, p. 12295
DNA replication in eukaryotic cells initiates from hundreds of origins along their genomes, leading to complete duplication of genetic information before...
Eukaryotes | Genomics | Cell division | Stochastic models | Deoxyribonucleic acid--DNA
Eukaryotes | Genomics | Cell division | Stochastic models | Deoxyribonucleic acid--DNA
Journal Article
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Systematic exploration of the ciliary protein landscape by large-scale affinity proteomics
Cilia, ISSN 2046-2530, 07/2015, Volume 4, Issue 1, p. P89
Journal Article
Journal of Infection, ISSN 0163-4453, 2008, Volume 57, Issue 5, pp. 418 - 420
Journal Article
2007 IEEE/RSJ International Conference on Intelligent Robots and Systems, ISSN 2153-0858, 10/2007, pp. 827 - 832
An integrated system for a power-aware robotic-centric exploratory lunar mission is the subject of this article. The robots communicate with a base station...
Base stations | Power supplies | Photovoltaic cells | Laser mode locking | Moon | Optical network units | Mobile robots | Laser beams | Robotics and automation | Intelligent robots
Base stations | Power supplies | Photovoltaic cells | Laser mode locking | Moon | Optical network units | Mobile robots | Laser beams | Robotics and automation | Intelligent robots
Conference Proceeding
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