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1. Full Text Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
by Mahajan, Anubha and Wessel, Jennifer and Willems, Sara M and Zhao, Wei and Robertson, Neil R and Chu, Audrey Y and Gan, Wei and Kitajima, Hidetoshi and Taliun, Daniel and Rayner, N. William and Guo, Xiuqing and Lu, Yingchang and Li, Man and Jensen, Richard A and Hu, Yao and Huo, Shaofeng and Lohman, Kurt K and Zhang, Weihua and Cook, James P and Prins, Bram Peter and Flannick, Jason and Grarup, Niels and Trubetskoy, Vassily Vladimirovich and Kravic, Jasmina and Kim, Young Jin and Rybin, Denis V and Yaghootkar, Hanieh and Mueller-Nurasyid, Martina and Meidtner, Karina and Li-Gao, Ruifang and Varga, Tibor V and Marten, Jonathan and Li, Jin and Smith, Albert Vernon and An, Ping and Ligthart, Symen and Gustafsson, Stefan and Malerba, Giovanni and Demirkan, Ayse and Tajes, Juan Fernandez and Steinthorsdottir, Valgerdur and Wuttke, Matthias and Lecoeur, Cecile and Preuss, Michael and Bielak, Lawrence F and Graff, Marielisa and Highland, Heather M and Justice, Anne E and Liu, Dajiang J and Marouli, Eirini and Peloso, Gina Marie and Warren, Helen R and Afaq, Saima and Afzal, Shoaib and Ahlqvist, Emma and Almgren, Peter and Amin, Najaf and Bang, Lia B and Bertoni, Alain G and Bombieri, Cristina and Bork-Jensen, Jette and Brandslund, Ivan and Brody, Jennifer A and Burtt, Noel P and Canouil, Mickael and Chen, Yii-Der Ida and Cho, Yoon Shin and Christensen, Cramer and Eastwood, Sophie V and Eckardt, Kai-Uwe and Fischer, Krista and Gambaro, Giovanni and Giedraitis, Vilmantas and Grove, Megan L and de Haan, Hugoline G and Hackinger, Sophie and Hai, Yang and Han, Sohee and Tybjaerg-Hansen, Anne and Hivert, Marie-France and Isomaa, Bo and Jager, Susanne and Jorgensen, Marit E and Jorgensen, Torben and Karajamaki, Annemari and Kim, Bong-Jo and Kim, Sung Soo and Koistinen, Heikki A and Kovacs, Peter and Kriebel, Jennifer and Kronenberg, Florian and Lall, Kristi and Lange, Leslie A and Lee, Jung-Jin and Lehne, Benjamin and Li, Huaixing and Lin, Keng-Hung and Linneberg, Allan and Liu, Ching-Ti and Liu, Jun and ... and MAGIC Consortium and ExomeBP Consortium and GIANT Consortium
Nature genetics, ISSN 1061-4036, 04/2018, Volume 50, Issue 4, pp. 559 - 571
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Diabetes Mellitus, Type 2 - classification | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Diabetes Mellitus, Type 2 - genetics | Humans | Male | Genome-Wide Association Study - statistics & numerical data | Genetic Variation | Diabetes Mellitus, Type 2 - physiopathology | Alleles | Female | Chromosome Mapping - statistics & numerical data | Whole Exome Sequencing - statistics & numerical data | Type 2 diabetes | Genome-wide association studies | Usage | Genetic aspects | Risk factors | Exome sequencing | Index Medicus
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2. Full Text High-throughput discovery of novel developmental phenotypes
by Dickinson, Mary E and Flenniken, Ann M and Ji, Xiao and Teboul, Lydia and Wong, Michael D and White, Jacqueline K and Meehan, Terrence F and Weninger, Wolfgang J and Westerberg, Henrik and Adissu, Hibret and Baker, Candice N and Bower, Lynette and Brown, James M and Brianna Caddle, L and Chiani, Francesco and Clary, Dave and Cleak, James and Daly, Mark J and Denegre, James M and Doe, Brendan and Dolan, Mary E and Edie, Sarah M and Fuchs, Helmut and Gailus-Durner, Valerie and Galli, Antonella and Gambadoro, Alessia and Gallegos, Juan and Guo, Shiying and Horner, Neil R and Hsu, Chih-wei and Johnson, Sara J and Kalaga, Sowmya and Keith, Lance C and Lanoue, Louise and Lawson, Thomas N and Lek, Monkol and Mark, Manuel and Marschall, Susan and Mason, Jeremy and McElwee, Melissa L and Newbigging, Susan and Nutter, Lauryl M.J and Peterson, Kevin A and Ramirez-Solis, Ramiro and Rowland, Douglas J and Ryder, Edward and Samocha, Kaitlin E and Seavitt, John R and Selloum, Mohammed and Szoke-Kovacs, Zsombor and Tamura, Masaru and Trainor, Amanda G and Tudose, Ilinca and Wakana, Shigeharu and Warren, Jonathan and Wendling, Olivia and West, David B and Wong, Leeyean and Yoshiki, Atsushi and MacArthur, Daniel G and Tocchini-Valentini, Glauco P and Gao, Xiang and Flicek, Paul and Bradley, Allan and Skarnes, William C and Justice, Monica J and Parkinson, Helen E and Moore, Mark and Wells, Sara and Braun, Robert E and Svenson, Karen L and Hrabe de Angelis, Martin and Herault, Yann and Mohun, Tim and Mallon, Ann-Marie and Mark Henkelman, R and Brown, Steve D.M and Adams, David J and Kent Lloyd, K.C and McKerlie, Colin and Beaudet, Arthur L and Bucan, Maja and Murray, Stephen A and McKay, Matthew and Urban, Barbara and Lund, Caroline and Froeter, Erin and LaCasse, Taylor and Mehalow, Adrienne and Gordon, Emily and Donahue, Leah Rae and Taft, Robert and Kutney, Peter and Dion, Stephanie and Goodwin, Leslie and Kales, Susan and Urban, Rachel and Palmer, Kristina and Pertuy, Fabien and Bitz, Deborah and ... and Int Mouse Phenotyping Consortium and The International Mouse Phenotyping Consortium
Nature (London), ISSN 0028-0836, 09/2016, Volume 537, Issue 7621, pp. 508 - 514
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genetic research | Phenotype | Research | High-throughput screening (Biochemical assaying) | Methods | Genotype & phenotype | Disease | Developmental biology | Genes | Genomes | Mutation | Embryos | Index Medicus | knockout | embryonic lethal | mouse | KOMP | IMPC | EUCOMM
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3. Full Text Defining the role of common variation in the genomic and biological architecture of adult human height
by Wood, Anew R and Esko, Tonu and Yang, Jian and Vedantam, Sailaja and Pers, Tune H and Gustafsson, Stefan and Chu, Auey Y and Estrada, Karol and Luan, Jian'an and Kutalik, Zoltán and Amin, Najaf and Buchkovich, Martin L and Croteau-Chonka, Damien C and Day, Felix R and Duan, Yanan and Fall, Tove and Fehrmann, Rudolf and Ferreira, Teresa and Jackson, Anne U and Karjalainen, Juha and Lo, Ken Sin and Locke, Adam E and Mägi, Reedik and Mihailov, Evelin and Porcu, Eleonora and Randall, Joshua C and Scherag, Ané and Vinkhuyzen, Anna A. E and Westra, Harm-Jan and Winkler, Thomas W and Workalemahu, Tsegaselassie and Zhao, Jing Hua and Absher, Devin and Albrecht, Eva and Anderson, Denise and Baron, Jeffrey and Beekman, Marian and Demirkan, Ayse and Ehret, Georg B and Feenstra, Bjarke and Feitosa, Mary F and Fischer, Krista and Fraser, Ross M and Goel, Anuj and Gong, Jian and Justice, Anne E and Kanoni, Stavroula and van der Velde, Nathalie and Hovingh, G. Kees and Kastelein, John J. P and PAGE Consortium and MIGen Consortium and LifeLines Cohort Study and Elect Med Records & Genom eMERGE C and Electronic Medical Records and Genomics (eMEMERGEGE) Consortium and PAGEGE Consortium and The MIGen Consortium and The PAGE Consortium and The Electronic Medical Records and Genomics (eMERGE) Consortium and The LifeLines Cohort Study and Göteborgs universitet and Gothenburg University and Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
Nature genetics, ISSN 1061-4036, 2014, Volume 46, Issue 11, pp. 1173 - 1186
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetics, Population | European Continental Ancestry Group - genetics | Analysis of Variance | Oligonucleotide Array Sequence Analysis | Humans | Polymorphism, Single Nucleotide - genetics | Adult | Genetic Variation - genetics | Genome-Wide Association Study - methods | Body Height - genetics | Stature | Genome-wide association studies | Genetic variation | Genes | Genetic aspects | Research | Identification and classification | Studies | Genomes | Genealogy | Architecture | Statistics | Index Medicus | Medicinsk genetik | Medical Genetics | GENETIC-VARIATION | SNPS | MUTATIONS | COMPLEX TRAITS | HERITABILITY | complex traits | mutations | snps | genetic-variation | heritability
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4. Full Text Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy
by Kovacs, Gabor G and Ferrer, Isio and Grinberg, Lea T and Alafuzoff, Irina and Attems, Johannes and Budka, Herbert and Cairns, Nigel J and Crary, John F and Duyckaerts, Charles and Ghetti, Bernardino and Halliday, Glenda M and Ironside, James W and Love, Seth and Mackenzie, Ian R and Munoz, David G and Murray, Melissa E and Nelson, Peter T and Takahashi, Hitoshi and Trojanowski, John Q and Ansorge, Olaf and Arzberger, Thomas and Baborie, Atik and Beach, Thomas G and Bieniek, Kevin F and Bigio, Eileen H and Bodi, Istvan and Dugger, Brittany N and Feany, Mel and Gelpi, Ellen and Gentleman, Stephen M and Giaccone, Giorgio and Hatanpaa, Kimmo J and Heale, Richard and Hof, Patrick R and Hofer, Monika and Hortobagyi, Tibor and Jellinger, Kurt and Jicha, Gregory A and Ince, Paul and Kofler, Julia and Koevari, Enikoe and Kril, Jillian J and Mann, David M and Matej, Radoslav and McKee, Ann C and McLean, Catriona and Milenkovic, Ivan and Montine, Thomas J and Murayama, Shigeo and Lee, Edward B and Rahimi, Jasmin and Roiguez, Roberta D and Rozemuller, Annemieke and Schneider, Julie A and Schultz, Christian and Seeley, William and Seilhean, Danielle and Smith, Colin and Tagliavini, Fabrizio and Takao, Masaki and Thal, Dietmar Rudolf and Toledo, Jon B and Tolnay, Markus and Troncoso, Juan C and Vinters, Harry V and Weis, Serge and Wharton, Stephen B and White, Charles L., III and Wisniewski, Thomas and Woulfe, John M and Yamada, Masahito and Dickson, Dennis W
Acta neuropathologica, ISSN 0001-6322, 01/2016, Volume 131, Issue 1, pp. 87 - 102
Aging | Tau | ARTAG | Tau astrogliopathy | Pathology | Neurosciences | Medicine & Public Health | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Astrocytes - cytology | Brain - metabolism | Tauopathies - metabolism | Animals | Neuroglia - pathology | Humans | Brain - pathology | Tauopathies - pathology | tau Proteins - metabolism | Immunohistochemistry | Neurophysiology | Index Medicus | Envelliment cerebral | Astròcits | Neurodegenerative diseases | Malalties neurodegeneratives | Aging brain | Astrocytes
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5. Full Text Identification of rare sequence variation underlying heritable pulmonary arterial hypertension
by Graf, Stefan and Haimel, Matthias and Bleda, Marta and Hadinnapola, Charaka and Southgate, Laura and Li, Wei and Hodgson, Joshua and Liu, Bin and Salmon, Richard M and Southwood, Mark and Machado, Rajiv D and Martin, Jennifer M and Treacy, Carmen M and Yates, Katherine and Daugherty, Louise C and Shamardina, Olga and Whitehorn, Deborah and Holden, Simon and Aled, Micheala and Bogaard, Harm J and Church, Colin and Coghlan, Gerry and Condliffe, Robin and Corris, Paul A and Danesino, Cesare and Eyries, Melanie and Gall, Henning and Ghio, Stefano and Ghofrani, Hossein-Ardeschir and Gibbs, J. Simon R and Girerd, Barbara and Houweling, Arjan C and Howard, Luke and Humbert, Marc and Kiely, David G and Kovacs, Gabor and Ross, Robert V. MacKenzie and Moledina, Shahin and Montani, David and Newnham, Michael and Olschewski, Anea and Olschewski, Horst and Peacock, Anew J and Pepke-Zaba, Joanna and Prokopenko, Inga and Rhodes, Christopher J and Scelsi, Laura and Seeger, Werner and Soubrier, Florent and Stein, Dan F and Suntharalingam, Jay and Swietlik, Emilia M and Toshner, Mark R and van Heel, David A and Noordegraaf, Anton Vonk and Waisfisz, Quinten and Wharton, John and Wort, Stephen J and Ouwehand, Willem H and Soranzo, Nicole and Lawrie, Allan and Upton, Paul D and Wilkins, Martin R and Trembath, Richard C and Morrell, Nicholas W
Nature communications, ISSN 2041-1723, 04/2018, Volume 9, Issue 1, pp. 1416 - 16
a_open_article_in_open_journal | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Prognosis | Humans | Male | Familial Primary Pulmonary Hypertension - diagnosis | SOXF Transcription Factors - metabolism | Aquaporin 1 - metabolism | Case-Control Studies | Familial Primary Pulmonary Hypertension - metabolism | Membrane Transport Proteins - genetics | Base Sequence | HEK293 Cells | Adult | Female | Growth Differentiation Factors - genetics | Membrane Transport Proteins - metabolism | Familial Primary Pulmonary Hypertension - pathology | Genetic Predisposition to Disease | Bone Morphogenetic Protein Receptors, Type II - genetics | Signal Transduction | Gene Expression Regulation | Adenosine Triphosphatases - metabolism | Models, Molecular | Familial Primary Pulmonary Hypertension - genetics | Bone Morphogenetic Protein Receptors, Type II - metabolism | Membrane Transport Proteins - chemistry | Whole Genome Sequencing | Aquaporin 1 - chemistry | Aquaporin 1 - genetics | Growth Differentiation Factors - metabolism | Transforming Growth Factor beta - genetics | Adenosine Triphosphatases - chemistry | Adenosine Triphosphatases - genetics | Mutation | SOXF Transcription Factors - genetics | Transforming Growth Factor beta - metabolism | SOXF Transcription Factors - chemistry | Growth Differentiation Factors - chemistry | Hypertension | Bone morphogenetic protein receptor type II | Secretion | Transforming growth factor | Genes | Genomes | Heritability | Aquaporin 1 | Pulmonary hypertension | Gene sequencing | Index Medicus
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6. Full Text Relationship Between Residual Plasma Viremia and the Size of HIV Proviral DNA Reservoirs in Infected Individuals Receiving Effective Antiretroviral Therapy
by Tae-Wook Chun and Danielle Murray and J. Shawn Justement and Claire W. Hallahan and Susan Moir and Colin Kovacs and Anthony S. Fauci
The Journal of infectious diseases, ISSN 0022-1899, 7/2011, Volume 204, Issue 1, pp. 135 - 138
Polymerase chain reaction | Statistical median | HIV/AIDS | Antiretrovirals | HIV | RNA | Viremia | DNA | Stem cells | Blood plasma | Arts | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Infectious diseases | Viral diseases | Viral diseases of the lymphoid tissue and the blood. Aids | Biological and medical sciences | Medical sciences | Human viral diseases | Proviruses - isolation & purification | HIV Infections - virology | Humans | Middle Aged | Male | HIV - immunology | HIV - isolation & purification | Plasma - virology | Anti-HIV Agents - administration & dosage | Antiretroviral Therapy, Highly Active | CD4-Positive T-Lymphocytes - immunology | DNA, Viral - blood | HIV Infections - immunology | Adult | Female | HIV Infections - drug therapy | Aged | Index Medicus | Abridged Index Medicus | Major and Brief Reports
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