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index medicus (7) 7
humans (5) 5
animals (4) 4
human monoclonal-antibodies (4) 4
article (3) 3
phosphorylation (3) 3
plasma cells - immunology (3) 3
vaccines (3) 3
antibodies, monoclonal - immunology (2) 2
antibodies, neutralizing - immunology (2) 2
antibodies, viral - immunology (2) 2
b-lymphocytes - immunology (2) 2
biochemistry & molecular biology (2) 2
bone-marrow (2) 2
cell biology (2) 2
endothelial cells - drug effects (2) 2
endothelial cells - metabolism (2) 2
female (2) 2
hiv-1 vaccine (2) 2
immunology (2) 2
lipopolysaccharides - pharmacology (2) 2
lps (2) 2
medicine, research & experimental (2) 2
membrane proteins - metabolism (2) 2
nadh oxidase (2) 2
nadph oxidases - metabolism (2) 2
neutralizing antibodies (2) 2
oxygen (2) 2
physiology (2) 2
reactive oxygen species (2) 2
reactive oxygen species - metabolism (2) 2
research article (2) 2
rhesus macaques (2) 2
rodents (2) 2
saids vaccines - immunology (2) 2
simian acquired immunodeficiency syndrome - immunology (2) 2
simian immunodeficiency virus - immunology (2) 2
smooth-muscle-cells (2) 2
spotlight (2) 2
transcription factors (2) 2
viral envelope proteins - immunology (2) 2
virology (2) 2
1-methyl-3-isobutylxanthine - pharmacology (1) 1
actin-binding protein (1) 1
actins - metabolism (1) 1
activation (1) 1
active transport, cell nucleus (1) 1
adaptive immunity (1) 1
adenoviruses (1) 1
adjuvant activity (1) 1
adjuvants (1) 1
adjuvants, immunologic (1) 1
adolescent (1) 1
adult (1) 1
aids (1) 1
aids vaccine (1) 1
aids vaccines - immunology (1) 1
aids/hiv (1) 1
alpha (1) 1
analysis (1) 1
angiotensin-ii (1) 1
antibody responses (1) 1
antibody-dependent enhancement (1) 1
antigens (1) 1
antigens - immunology (1) 1
antigens, cd - metabolism (1) 1
antigens, viral - immunology (1) 1
antiretroviral therapy (1) 1
aorta (1) 1
aorta - metabolism (1) 1
aorta - physiology (1) 1
arntl transcription factors - deficiency (1) 1
arntl transcription factors - genetics (1) 1
arteries (1) 1
b cells (1) 1
b-cell depletion (1) 1
barrier dysfunction (1) 1
barrier enhancement (1) 1
barrier function (1) 1
benzoquinones - pharmacology (1) 1
biochemical research methods (1) 1
biology (1) 1
blood-pressure (1) 1
blotting, western (1) 1
bmal1 protein (1) 1
c-terminal region (1) 1
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calcium - metabolism (1) 1
camp response element binding protein binding protein (1) 1
capillary permeability - drug effects (1) 1
cardiovascular system (1) 1
carrier proteins - metabolism (1) 1
cbp/p300 (1) 1
cd4-positive t-lymphocytes - immunology (1) 1
cd4-positive t-lymphocytes - metabolism (1) 1
cell adhesion molecules - genetics (1) 1
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1. Full Text Circadian Clock Control of Nox4 and Reactive Oxygen Species in the Vasculature
by Anea, Ciprian B and Zhang, Maoxiang and Chen, Feng and Ali, M. Irfan and Hart, C. Michael M and Stepp, David W and Kovalenkov, Yevgeniy O and Merloiu, Ana-Maria and Pati, Paramita and Fulton, David and Rudic, R. Daniel
PLoS ONE, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, pp. e78626 - e78626
Recent studies have shown that circadian clock disruption is associated with pathological remodeling in the arterial structure and vascular stiffness.... 
OXIDATIVE STRESS | NAD(P)H OXIDASE | SUPEROXIDE | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | SMOOTH-MUSCLE-CELLS | ANGIOTENSIN-II | MICE | DYSFUNCTION | NADPH OXIDASES | BLOOD-PRESSURE | ARNTL Transcription Factors - genetics | Reactive Oxygen Species - metabolism | Humans | Gene Expression Regulation | NADPH Oxidases - metabolism | Aorta - metabolism | NADPH Oxidase 4 | Gene Knockout Techniques | Promoter Regions, Genetic - genetics | Hydrogen Peroxide - metabolism | ARNTL Transcription Factors - deficiency | Animals | Circadian Clocks | NADPH Oxidases - genetics | Mice | Aorta - physiology | Oxidases | Hydrogen peroxide | Genes | Superoxide | Genetic transcription | DNA binding proteins | Endothelium | Regulators | Reactive oxygen species | Transcription factors | Oscillations | Smooth muscle | Biology | NAD(P)H oxidase | Arteries | Proteins | Signal transduction | NOX4 gene | Toxicology | NOX4 protein | Rodents | Aorta | Physiology | Stiffness | Growth factors | Species | Hydrogen ion concentration | Circadian rhythms | Hypertension | Oxygen | Muscles | Pharmacology | Rhythms | Circadian rhythm | Gene expression | Endothelial cells | Signaling | Coronary vessels | BMAL1 protein | Disruption | Laboratory animals | Index Medicus
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2. Full Text B cell responses during secondary dengue virus infection are dominated by highly cross-reactive, memory-derived plasmablasts
by Priyamvada, Lalita and Cho, Alice and Onlamoon, Nattawat and Zheng, Nai-Ying and Huang, Min and Kovalenkov, Yevgeniy and Chokephaibulkit, Kulkanya and Angkasekwinai, Nasikarn and Pattanapanyasat, Kovit and Ahmed, Rafi and Wilson, Patrick C and Wrammert, Jens
Journal of Virology, ISSN 0022-538X, 06/2016, Volume 90, Issue 12, pp. 5574 - 5585
Dengue virus (DENV) infection results in the production of both type-specific and cross-neutralizing antibodies. While immunity to the infecting serotype is... 
ANTIBODY-DEPENDENT ENHANCEMENT | ORIGINAL ANTIGENIC SIN | IMMUNITY | NEUTRALIZING ANTIBODIES | RISK-FACTORS | VIROLOGY | SHOCK SYNDROME | HEMORRHAGIC-FEVER | DISEASE SEVERITY | IN-DEPTH ANALYSIS | HUMAN MONOCLONAL-ANTIBODIES | Antibody-Dependent Enhancement | Humans | Middle Aged | Serogroup | Male | Dengue - physiopathology | Dengue - virology | Cross Reactions | Young Adult | Antibodies, Neutralizing - immunology | B-Lymphocytes - immunology | Dengue Virus - immunology | Adolescent | Adult | Antibodies, Viral - immunology | Female | Immunologic Memory | Viral Envelope Proteins - immunology | Dengue - immunology | Antibodies, Monoclonal - immunology | Epitopes, B-Lymphocyte | Plasma Cells - immunology | Index Medicus
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3. Full Text Adjuvanting a simian immunodeficiency virus vaccine with toll-like receptor ligands encapsulated in nanoparticles induces persistent antibody responses and enhanced protection in trim5α restrictive macaques
by Kasturi, Sudhir Pai and Kozlowski, Pamela A and Nakaya, Helder I and Burger, Matheus C and Russo, Pedro and Pham, Mathew and Kovalenkov, Yevgeniy and Silveira, Eduardo L.V and Havenar-Daughton, Colin and Burton, Samantha L and Kilgore, Katie M and Johnson, Mathew J and Nabi, Rafiq and Legere, Traci and Sher, Zarpheen Jinnah and Chen, Xuemin and Amara, Rama R and Hunter, Eric and Bosinger, Steven E and Spearman, Paul and Crotty, Shane and Villinger, Francois and Derdeyn, Cynthia A and Wrammert, Jens and Pulendran, Bali
Journal of Virology, ISSN 0022-538X, 2017, Volume 91, Issue 4
Our previous work has shown that antigens adjuvanted with ligands specific for Toll-like receptor 4 (TLR4) and TLR7/8 encapsulated in poly(lactic-co-glycolic)... 
TLR ligands | SIV | Plasmablasts | Plasma cells | Rhesus macaques | Adjuvants | Antibody responses | Vaccine | HIV vaccines | plasmablasts | CELLULAR-IMMUNITY | plasma cells | VAGINAL SHIV CHALLENGE | vaccine | VIROLOGY | rhesus macaques | SYNERGISTICALLY TRIGGER | NONNEUTRALIZING ANTIBODIES | HUMORAL IMMUNITY | SIV CHALLENGES | HUMAN MONOCLONAL-ANTIBODIES | antibody responses | HIV-1 VACCINE | adjuvants | INNATE IMMUNITY | Simian Acquired Immunodeficiency Syndrome - metabolism | Simian Acquired Immunodeficiency Syndrome - mortality | Gene Expression Profiling | CD4-Positive T-Lymphocytes - immunology | Nanoparticles | Immunoglobulin G - immunology | Female | Immunization Schedule | Plasma Cells - metabolism | Simian Immunodeficiency Virus - immunology | SAIDS Vaccines - administration & dosage | Adjuvants, Immunologic | CD4-Positive T-Lymphocytes - metabolism | Toll-Like Receptor 4 - metabolism | Simian Acquired Immunodeficiency Syndrome - prevention & control | Antigens, Viral - immunology | Animals | Carrier Proteins - metabolism | SAIDS Vaccines - immunology | Simian Acquired Immunodeficiency Syndrome - immunology | Lymphocyte Count | Antibodies, Viral - immunology | Ligands | Viral Envelope Proteins - immunology | Cluster Analysis | Plasma Cells - immunology | Index Medicus
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4. Full Text Vaccine-induced plasmablast responses in rhesus macaques: Phenotypic characterization and a source for generating antigen-specific monoclonal antibodies
by Silveira, Eduardo L.V and Kasturi, Sudhir P and Kovalenkov, Yevgeniy and Rasheed, Ata Ur and Yeiser, Patryce and Jinnah, Zarpheen S and Legere, Traci H and Pulendran, Bali and Villinger, Francois and Wrammert, Jens
Journal of Immunological Methods, ISSN 0022-1759, 01/2015, Volume 416, pp. 69 - 83
Over 100 broadly neutralizing antibodies have been isolated from a minority of HIV infected patients, but the steps leading to the selection of plasma cells... 
Monoclonal antibodies | Macaque plasmablasts | Phenotype | Sorting | MULTIPLE-MYELOMA | VIRUS-INFECTION | NEUTRALIZING ANTIBODIES | BONE-MARROW | BIOCHEMICAL RESEARCH METHODS | ANTIRETROVIRAL THERAPY | IMMUNOLOGY | SINGLE-CELL | MEMORY B-CELLS | SECRETING CELLS | SIV INFECTION | HIV-1 VACCINE | AIDS Vaccines - immunology | Macaca mulatta - immunology | Vaccines - immunology | HIV - immunology | Cell Separation - methods | Enzyme-Linked Immunospot Assay - methods | HIV Infections - immunology | Macaca mulatta - virology | Antibodies, Neutralizing - immunology | Animals | B-Lymphocytes - immunology | SAIDS Vaccines - immunology | Simian Acquired Immunodeficiency Syndrome - immunology | Antigens - immunology | Models, Animal | Antibodies, Monoclonal - immunology | Immunologic Memory - immunology | Plasma Cells - immunology | Simian Immunodeficiency Virus - immunology | Antigens | Vaccines | B cells | Analysis | Index Medicus | phenotype | sorting | monoclonal antibodies
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5. Full Text Nitric oxide reduces NADPH oxidase 5 (Nox5) activity by reversible S-nitrosylation
by Qian, Jin and Chen, Feng and Kovalenkov, Yevgeniy and Pandey, Deepesh and Moseley, M. Arthur and Foster, Matthew W and Black, Stephen M and Venema, Richard C and Stepp, David W and Fulton, David J.R
Free Radical Biology and Medicine, ISSN 0891-5849, 05/2012, Volume 52, Issue 9, pp. 1806 - 1819
The NADPH oxidases (Noxs) are a family of transmembrane oxidoreductases that produce superoxide and other reactive oxygen species (ROS). Nox5 was the last of... 
Reactive oxygen species | Free radicals | Nox5 | Nitric oxide | NADPH oxidase | S-nitrosylation | ACTIVATION | SUPEROXIDE-PRODUCTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENERATES SUPEROXIDE | SYNTHASE | OXYGEN | NAD(P)H OXIDASE | ENDOTHELIAL-CELLS | DISEASE | ENDOCRINOLOGY & METABOLISM | SMOOTH-MUSCLE-CELLS | PEROXYNITRITE-MEDIATED OXIDATION | Cell Line | Phosphorylation | Reactive Oxygen Species - metabolism | Calcium - metabolism | Humans | NADPH Oxidases - metabolism | Cercopithecus aethiops | Nitric Oxide - physiology | NADPH Oxidase 5 | Blotting, Western | Animals | Nitroso Compounds - metabolism | Mass Spectrometry | Membrane Proteins - metabolism | Nitric Oxide Donors - pharmacology | COS Cells | Index Medicus | Reactive Oxygen Species
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6. Full Text Molecular mechanisms mediating protective effect of cAMP on lipopolysaccharide (LPS)‐induced human lung microvascular endothelial cells (HLMVEC) hyperpermeability
by Bogatcheva, Natalia V and Zemskova, Marina A and Kovalenkov, Yevgeniy and Poirier, Christophe and Verin, Alexander D
Journal of Cellular Physiology, ISSN 0021-9541, 12/2009, Volume 221, Issue 3, pp. 750 - 759
Up to date, the nature of the sepsis‐induced vascular leakage is understood only partially, which limits pharmacological approaches for its management. Here we... 
VASP | PHYSIOLOGY | PERMEABILITY | PHOSPHORYLATION | C-TERMINAL REGION | KINASE | ENDOTOXIN | BARRIER ENHANCEMENT | FILAMIN | SEPSIS | ACTIN-BINDING PROTEIN | CELL BIOLOGY | Endothelium, Vascular - cytology | RNA, Small Interfering - genetics | Cell Adhesion Molecules - genetics | Contractile Proteins - genetics | Cadherins - metabolism | Humans | Actins - metabolism | Capillary Permeability - drug effects | Endothelium, Vascular - drug effects | Lung - cytology | Phosphoproteins - metabolism | Antigens, CD - metabolism | Cyclic AMP - analogs & derivatives | Guanine Nucleotide Exchange Factors - metabolism | Membrane Proteins - metabolism | Microfilament Proteins - metabolism | Phosphorylation - drug effects | Contractile Proteins - metabolism | Cyclic AMP - metabolism | Microfilament Proteins - genetics | Cyclic AMP-Dependent Protein Kinases - metabolism | Colforsin - pharmacology | Endothelial Cells - metabolism | Endothelium, Vascular - physiopathology | Electric Impedance | Phosphoproteins - genetics | Cell Adhesion Molecules - metabolism | Guanine Nucleotide Exchange Factors - agonists | 1-Methyl-3-isobutylxanthine - pharmacology | Filamins | Cyclic AMP - pharmacology | Zonula Occludens-1 Protein | Endothelial Cells - cytology | Lipopolysaccharides - pharmacology | Endothelial Cells - drug effects | Index Medicus | filamin | Epac | barrier dysfunction | LPS | PKA
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7. Full Text Novel mechanism of attenuation of LPS-induced NF-κB activation by the heat shock protein 90 inhibitor, 17-N-allylamino-17-demethoxygeldanamycin, in human lung microvascular endothelial cells
by Thangjam, Gagan S and Dimitropoulou, Chistiana and Joshi, Atul D and Barabutis, Nektarios and Shaw, Mary C and Kovalenkov, Yevgeniy and Wallace, Chistopher M and Fulton, David J and Patel, Vijay and Catravas, John D
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 2014, Volume 50, Issue 5, pp. 942 - 952
Heat shock protein (hsp) 90 inhibition attenuates NF-kappa B activation and blocks inflammation. However, the precise mechanism of NF-kappa B regulation by... 
NF-κB | Human lung microvascular endothelial cells | Heat shock protein 90 inhibitor | CAMP response element binding protein binding protein | LPS | human lung microvascular endothelial cells | COMPLEX | cAMP response element binding protein binding protein | heat shock protein 90 inhibitor | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | BARRIER FUNCTION | CBP/P300 | ALPHA | INDUCTION | P65 | COACTIVATORS | CELL BIOLOGY | NF-kappa B | RESPIRATORY SYSTEM | INFLAMMATION | EXPRESSION | Phosphorylation | Humans | Microvessels - metabolism | NF-kappa B - metabolism | I-kappa B Proteins - metabolism | I-kappa B Proteins - genetics | Ubiquitination | HSP90 Heat-Shock Proteins - genetics | Lung - metabolism | Active Transport, Cell Nucleus | Promoter Regions, Genetic | NF-kappa B - antagonists & inhibitors | Histone Deacetylases - genetics | Endothelial Cells - metabolism | Cells, Cultured | Microvessels - drug effects | Histone Deacetylases - metabolism | Down-Regulation - drug effects | Lactams, Macrocyclic - pharmacology | Benzoquinones - pharmacology | Histones - genetics | NF-kappa B - genetics | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Lung - drug effects | Lipopolysaccharides - pharmacology | HSP90 Heat-Shock Proteins - metabolism | Histones - metabolism | Endothelial Cells - drug effects | Index Medicus | Original Research
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8. Full Text Articles of Significant Interest Selected from This Issue by the Editors
Journal of Virology, ISSN 0022-538X, 06/2016, Volume 90, Issue 12, pp. 5533 - 5533
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9. Full Text Novel Mechanism of Attenuation of LPS-Induced NF-kB Activation by the Heat Shock Protein 90 Inhibitor, 17-N-allylamino-17-demethoxygeldanamycin, in Human Lung Microvascular Endothelial Cells
by Gagan S Thangjam and Chistiana Dimitropoulou and Atul D Joshi and Nektarios Barabutis and Mary C Shaw and Yevgeniy Kovalenkov and Chistopher M Wallace and David J Fulton and Vijay Patel and John D Catravas
American Journal of Respiratory Cell and Molecular Biology (Online), 05/2014, Volume 50, Issue 5, pp. 942 - 942
Heat shock protein (hsp) 90 inhibition attenuates NF-... activation and blocks inflammation. However, the precise mechanism of NF-... regulation by hsp90 in... 
Cell culture | Transcription factors | Rodents | Adenoviruses | Heat shock proteins | RNA polymerase | Kinases | Deoxyribonucleic acid--DNA | Recruitment
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10. Full Text Abstracts of the HIV Research for Prevention Meeting, HIVR4P, 17-20 October, 2016, Chicago, USA
by Sullivan, Patrick and Yuan, Maoli and Coleman, John and Destefano, Joanne and Zhang, Xinsheng and Yates, Nicole and Barouch, Dan and Ackerman, Margaret and Decamp, Allan and Alter, Galit and Tomaras, Georgia and Tomaras, Georgia and Montefiori, David and Montefiori, David and Rasmussen, Beth and Morrow, Gavin and Koff, Wayne and Kashuba, Angela and Kashuba, Angela and Mascola, John and Picker, Louis and Kent, Stephen and Selhorst, Philippe and Masson, Lindi and Ngandu, Nobubelo and Rademeyer, Cecilia and Karim, Quarraisha Abdool and Kijak, Gustavo and Barouch, Dan and Rasheed, Ata Ur and Havenar-Daughton, Colin and Pham, Matthew and Kovalenkov, Yevgeniy and Gumber, Sanjeev and Johnson, Matthew and Wrammert, Jens and Villinger, Francois and Haynes, Barton and Haynes, Barton and Fox, Christopher and Reed, Steve and Vasilakos, John and Tomai, Mark and Crotty, Shane and Ahmed, Rafi and Pulendran, Bali and Fukazawa, Yoshinori and Lifson, Jeffrey and Lifson, Jeffrey and Moore, Penny and Chatora, Kumbirai and Skorochod, Elisabeth and Madidi, Ngonidzashe and Gomez, Anabel and Ncube, Getrude and Sundaram, Maaya and Kretschmer, Steve and Pauthner, Matthias and Briney, Bryan and Lee, Jeong Hyun and Saye-Francisco, Karen and Hsueh, Jessica and Ramos, Alejandra and Le, Khoa and Jones, Meaghan and Jardine, Joseph and Bastidas, Raiza and Sarkar, Anita and Liang, Chi-Hui and Wilson, Ian and Ward, Andrew and Zhu, Jiang and Poignard, Pascal and Burton, Dennis and Krebs, Shelly and Law, Wiliam and Gift, Syna and Chenine, Agnes and Rolland, Morgane and Moody, M. Anthony and Jarosinski, Marissa and Georgiev, Ivelin and Chuang, Gwo-Yu and Chuang, Gwo-Yu and Asokan, Mangaiarkarasi and Bailer, Robert T and Cale, Evan M and Louder, Mark and Kwong, Peter D and Polonis, Victoria and Tovanabutra, Sodsai and Robb, Merlin and Mascola, John R and Wibmer, Constantinos Kurt and Wibmer, Constantinos Kurt and Madzorera, Vimbai S and Doria-Rose, Nicole A and Morris, Lynn and Moore, Penny L and Anthony, Colin and ...
AIDS Research and Human Retroviruses, ISSN 0889-2229, 10/2016, Volume 32, Issue S1, pp. 1 - 409
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11. Full Text Robust memory responses against influenza vaccination in pemphigus patients previously treated with rituximab
by Cho, A and Bradley, B and Kauffman, R and Priyamvada, L and Kovalenkov, Y and Feldman, R and Wrammert, J
JCI INSIGHT, ISSN 2379-3708, 06/2017, Volume 2, Issue 12
Rituximab is a therapeutic anti-CD20 monoclonal antibody widely used to treat B cell lymphoma and autoimmune diseases, such as rheumatic arthritis, systemic... 
RHEUMATOID-ARTHRITIS | UNITED-STATES | MEDICINE, RESEARCH & EXPERIMENTAL | SYSTEMIC-LUPUS-ERYTHEMATOSUS | IMMUNE THROMBOCYTOPENIA | B-CELL DEPLETION | BONE-MARROW | LIVED PLASMA-CELLS | PERIPHERAL-BLOOD | HUMAN MONOCLONAL-ANTIBODIES | CLINICAL-RESPONSE
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12. Full Text Vaccine induction of antibodies and tissue-resident CD8+ T cells enhances protection against mucosal SHIV-infection in young macaques
by Petitdemange, Caroline and Kasturi, Sudhir Pai and Kozlowski, Pamela A and Nabi, Rafiq and Quarnstrom, Clare F and Reddy, Pradeep Babu Jagadeesh and Derdeyn, Cynthia A and Spicer, Lori M and Patel, Parin and Legere, Traci and Kovalenkov, Yevgeniy O and Labranche, Celia C and Villinger, François and Tomai, Mark and Vasilakos, John and Haynes, Barton and Kang, C Yong and Gibbs, James S and Yewdell, Jonathan W and Barouch, Dan and Wrammert, Jens and Montefiori, David and Hunter, Eric and Amara, Rama R and Masopust, David and Pulendran, Bali
JCI insight, ISSN 2379-3708, 02/2019, Volume 4, Issue 4
Antibodies and cytotoxic T cells represent 2 arms of host defense against pathogens. We hypothesized that vaccines that induce both high-magnitude CD8(+) T... 
AIDS/HIV | Adaptive immunity | Vaccines | AIDS vaccine | MEDICINE, RESEARCH & EXPERIMENTAL | RESPONSES | CHALLENGE | VIREMIA | HIV | EFFICACY | YELLOW-FEVER VACCINE | ADJUVANT ACTIVITY | RECTAL SECRETIONS | HUMAN MONOCLONAL-ANTIBODIES | RHESUS MACAQUES
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