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Journal Article
Umeni, ISSN 0049-5123, 2015, Volume 63, Issue 6, pp. 485 - 491
Journal Article
PLoS Pathogens, ISSN 1553-7366, 08/2015, Volume 11, Issue 8, pp. e1005075 - e1005075
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2016, Volume 11, Issue 7, pp. e0159517 - e0159517
Background The nucleoside reverse transcriptase inhibitor (NRTI) 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA) in preclinical development exhibits improved... 
REVERSE-TRANSCRIPTASE INHIBITOR | POTENT ACTIVITY | TRANSMISSION | IMMUNODEFICIENCY-VIRUS-INFECTION | IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | T-CELL DEPLETION | ACTIVE ANTIRETROVIRAL THERAPY | IN-VIVO | CD4(+) | TYPE-1 INFECTION | Liver - virology | HIV-1 - pathogenicity | Liver - pathology | HIV Reverse Transcriptase - antagonists & inhibitors | Humans | Male | Reverse Transcriptase Inhibitors - administration & dosage | Thymus Gland - virology | Anti-HIV Agents - administration & dosage | HIV Infections - pathology | Liver - drug effects | Female | Bone Marrow - drug effects | Disease Models, Animal | Gastrointestinal Tract - virology | Virus Replication - drug effects | Bone Marrow - virology | Genes, Transgenic, Suicide | HIV-1 - drug effects | Reproductive Tract Infections - pathology | HIV Infections - virology | Deoxyadenosines - administration & dosage | Gastrointestinal Tract - drug effects | Thymus Gland - drug effects | Animals | Bone Marrow - pathology | Reproductive Tract Infections - virology | HIV Infections - drug therapy | Reproductive Tract Infections - drug therapy | Mice | CD4-Positive T-Lymphocytes - drug effects | Highly active antiretroviral therapy | Usage | Drug resistance | Health aspects | Analysis | RNA-directed DNA polymerase | Liver | Mucosa | Lung | Lymphocytes T | Infections | Lymph nodes | Thymus | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Antiretroviral agents | Nucleoside reverse transcriptase inhibitors | Animal tissues | Human immunodeficiency virus--HIV | Antiviral activity | Peripheral blood | Bone marrow | Drug therapy | Spleen | Antiretroviral drugs | Antiviral agents | Gastrointestinal tract | Lymphoid tissue | Ribonucleic acid--RNA | Deoxyadenosine | Antiretroviral therapy | CD4 antigen | Medicine | Depletion | Infectious diseases | Replication | Reproductive system | Laboratory animals | Index Medicus | RNA | Acquired immune deficiency syndrome | Ribonucleic acid | AIDS | HIV | Human immunodeficiency virus
Journal Article
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 4156 - 11
Non-adherence to medication is an important health care problem, especially in the treatment of chronic conditions. Injectable long-acting (LA) formulations of... 
AFRICAN WOMEN | TRANSMISSION | ANTIRETROVIRAL PROPHYLAXIS | HUMANIZED BLT MICE | MULTIDISCIPLINARY SCIENCES | INFECTION | DOLUTEGRAVIR | PREEXPOSURE PROPHYLAXIS | FORMULATION | FEMALE REPRODUCTIVE-TRACT | TENOFOVIR | HIV Infections - prevention & control | Virus Replication - drug effects | HIV-1 - drug effects | Virus Replication - genetics | HIV Infections - virology | Humans | Macaca mulatta | HIV-1 - genetics | Mice, SCID | Mice, Knockout | Anti-HIV Agents - administration & dosage | Tissue Distribution | Animals | HIV-1 - physiology | Time Factors | Anti-HIV Agents - pharmacokinetics | Heterocyclic Compounds, 3-Ring - administration & dosage | Heterocyclic Compounds, 3-Ring - therapeutic use | Anti-HIV Agents - therapeutic use | HIV Infections - drug therapy | Mice, Inbred NOD | Heterocyclic Compounds, 3-Ring - pharmacokinetics | Drug Delivery Systems - methods | Disease Models, Animal | Health care | Formulations | Medical research | Antiretroviral drugs | Antiviral agents | Animal models | Drug delivery systems | Viremia | Therapeutic applications | Liver | Clinical trials | Vagina | Drug delivery | Thymus | Prevention | Chronic conditions | Disease transmission | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Bone marrow | Primates | Mice | Mathematical models | Drug dosages | Index Medicus
Journal Article
Journal Article
Cell Metabolism, ISSN 1550-4131, 01/2015, Volume 21, Issue 1, pp. 81 - 94
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2016, Volume 126, Issue 3, pp. 892 - 904
The recently completed HIV prevention trials network study 052 is a landmark collaboration demonstrating that HIV transmission in discordant couples can be... 
MEDICINE, RESEARCH & EXPERIMENTAL | DENDRITIC CELLS | VAGINAL TRANSMISSION | HUMANIZED BLT MICE | ACTIVE ANTIRETROVIRAL THERAPY | IMMUNODEFICIENCY-VIRUS TYPE-1 | CD4(+) T-CELLS | PREEXPOSURE PROPHYLAXIS | SEXUAL TRANSMISSION | GENITAL-TRACT | RHESUS MACAQUES | Anti-HIV Agents - pharmacology | Cervix Uteri - secretion | HIV Infections - prevention & control | Coculture Techniques | Humans | Tenofovir - pharmacology | Vagina - immunology | RNA, Viral - blood | CD4-Positive T-Lymphocytes - immunology | Microbial Sensitivity Tests | Receptors, CCR5 - metabolism | HIV-1 - physiology | Female | HIV Infections - transmission | CD4-Positive T-Lymphocytes - virology | Cervix Uteri - virology | Vagina - secretion | HIV-1 - drug effects | HIV Infections - virology | Cells, Cultured | Mice, Transgenic | Mice, SCID | Animals | Virus Replication | CD8-Positive T-Lymphocytes - virology | Cervix Uteri - immunology | Vagina - virology | Mice, Inbred NOD | CD8-Positive T-Lymphocytes - immunology | Highly active antiretroviral therapy | Antiviral agents | T cells | HIV (Viruses) | Analysis | Reproductive organs, Female | Physiological aspects | Development and progression | HIV infection | Patient outcomes | Studies | Disease transmission | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Index Medicus | Abridged Index Medicus
Journal Article
Current Protocols in Immunology, ISSN 1934-3671, 04/2012, Volume Chapter 22, Issue 97, p. Unit 22F.10.1
Journal Article