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1. Full Text The clinical outcome of eribulin treatment in Japanese patients with advanced soft tissue sarcoma: a Tokai Musculoskeletal Oncology Consortium study
by Nakamura, Tomoki and Tsukushi, Satoshi and Asanuma, Kunihiro and Katagiri, Hirohisa and Ikuta, Kunihiro and Nagano, Akihito and Kozawa, Eiji and Yamada, Satoshi and Shido, Yoji and Yamada, Kenji and Kawanami, Katsuhisa and Ishimura, Daisuke and Sudo, Akihiro and Nishida, Yoshihiro
Clinical and Experimental Metastasis, ISSN 0262-0898, 2019, Volume 36, Issue 4, pp. 343 - 350
The efficacy and safety of eribulin in Japanese patients with advanced soft-tissue sarcomas (STS) have not been evaluated in a large-scale cohort study. Thus,... 
Soft tissue sarcoma | Efficacy | Eribulin | Overall survival | Progression-free survival | 1ST-LINE TREATMENT | THERAPY | PROGNOSTIC-FACTORS | PAZOPANIB | ONCOLOGY | DOXORUBICIN | Development and progression | Care and treatment | Metastasis | Sarcoma | Patient outcomes | Consortia | Tissue | Liposarcoma | Multivariate analysis | Survival | Patients | Tumors | Soft tissues | Metastases
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2. Full Text Feasibility and diagnostic performance of fractional flow reserve measurement derived from coronary computed tomography angiography in real clinical practice
by Kawaji, Tetsuma and Kawaji, Tetsuma and Shiomi, Hiroki and Shiomi, Hiroki and Morishita, Hiroshi and Morishita, Hiroshi and Morimoto, Takeshi and Morimoto, Takeshi and Taylor, Charles A and Taylor, Charles A and Kanao, Shotaro and Kanao, Shotaro and Koizumi, Koji and Koizumi, Koji and Kozawa, Satoshi and Kozawa, Satoshi and Morihiro, Kazuhisa and Morihiro, Kazuhisa and Watanabe, Hirotoshi and Watanabe, Hirotoshi and Tazaki, Junichi and Tazaki, Junichi and Imai, Masao and Imai, Masao and Saito, Naritatsu and Saito, Naritatsu and Shizuta, Satoshi and Shizuta, Satoshi and Ono, Koh and Ono, Koh and Togashi, Kaori and Togashi, Kaori and Kimura, Takeshi and Kimura, Takeshi
The International Journal of Cardiovascular Imaging, ISSN 1569-5794, 2/2017, Volume 33, Issue 2, pp. 271 - 281
Non-invasive fractional flow reserve measured by coronary computed tomography angiography (FFRCT) has demonstrated a high diagnostic accuracy for detecting... 
Medicine & Public Health | Coronary computed tomography angiography | Cardiology | Imaging / Radiology | Cardiac Imaging | Fractional flow reserve | Fractional flow reserve-computed tomography angiography | DESIGN | CARDIAC & CARDIOVASCULAR SYSTEMS | RATIONALE | GUIDELINES | STENOSES | CT ANGIOGRAPHY | NXT TRIAL | ACCURACY | Fractional flow reserve-computed tomography angiography | DE-FACTO | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | ARTERY-DISEASE | GUIDED PCI | Coronary Vessels - diagnostic imaging | Predictive Value of Tests | Prognosis | Prospective Studies | Area Under Curve | Coronary Vessels - physiopathology | Humans | Middle Aged | Vascular Calcification - diagnostic imaging | Male | Feasibility Studies | Cardiac Catheterization | Coronary Angiography - methods | Coronary Artery Disease - physiopathology | Vascular Calcification - physiopathology | Female | Radiographic Image Interpretation, Computer-Assisted | Severity of Illness Index | Reproducibility of Results | Cross-Sectional Studies | Computed Tomography Angiography | Myocardial Perfusion Imaging - methods | Coronary Artery Disease - diagnostic imaging | Fractional Flow Reserve, Myocardial | ROC Curve | Aged | Measurement | Medical colleges | CT imaging | Angiography | Cardiac patients | Rankings | Diagnosis | Coronary heart disease | Epidemiology | Cardiovascular agents
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3. Study of electron-beam and extreme-ultraviolet resist utilizing polarity change and radical crosslinking
by Enomoto, Satoshi and Kozawa, Takahiro
Journal of Vacuum Science and Technology B: Nanotechnology and Microelectronics, ISSN 2166-2746, 05/2018, Volume 36, Issue 3
Resists used for the fabrication of next-generation of semiconductor circuits must exhibit resolution better than 10 nm and sensitivity comparable to or better... 
PHOTOCHEMISTRY | NANOSCIENCE & NANOTECHNOLOGY | PHYSICS, APPLIED | BEHAVIOR | LITHOGRAPHY | ENGINEERING, ELECTRICAL & ELECTRONIC
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4. Full Text Extracorporeal cardiopulmonary resuscitation versus conventional cardiopulmonary resuscitation in adults with out-of-hospital cardiac arrest: A prospective observational study
by Sakamoto, Tetsuya and Morimura, Naoto and Nagao, Ken and Asai, Yasufumi and Yokota, Hiroyuki and Nara, Satoshi and Hase, Mamoru and Tahara, Yoshio and Atsumi, Takahiro and SAVE-J Study Grp and SAVE-J Study Group
Resuscitation, ISSN 0300-9572, 2014, Volume 85, Issue 6, pp. 762 - 768
Abstract Background A favorable neurological outcome is likely to be achieved in out-of-hospital cardiac arrest (OHCA) patients with ventricular fibrillation... 
Emergency | Percutaneous cardiopulmonary support | Out-of-hospital cardiac arrest | Advanced life support | Cardiopulmonary resuscitation | Extracorporeal cardiopulmonary resuscitation | Ventricular fibrillation | STATEMENT | HYPOTHERMIA | BYPASS | SOS-KANTO | GUIDELINES | INTERNATIONAL LIAISON COMMITTEE | PERCUTANEOUS CORONARY INTERVENTION | LIFE-SUPPORT | EMERGENCY MEDICINE | OUTCOMES | MEMBRANE-OXYGENATION | CRITICAL CARE MEDICINE | Out-of-Hospital Cardiac Arrest - therapy | Cardiopulmonary Resuscitation - methods | Extracorporeal Membrane Oxygenation | Prospective Studies | Humans | Middle Aged | Adult | Female | Male | Electrocardiography | Tachycardia | Adults | CPR (First aid) | Electrocardiogram | Cardiac arrest
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5. Full Text Effects of an organotin compound on radiation-induced reactions of extreme-ultraviolet resists utilizing polarity change and radical crosslinking
by Enomoto, Satoshi and Yoshino, Takumi and Machida, Kohei and Kozawa, Takahiro
Japanese Journal of Applied Physics, ISSN 0021-4922, 01/2019, Volume 58, Issue 1, p. 16504
Non-chemically amplified resists (non-CARS) are generally less sensitive to radiation than CARs due to the lack of an amplification mechanism. Recently, a... 
DYNAMICS | PHYSICS, APPLIED | LITHOGRAPHY | Radiation effects | Crosslinking | Attenuation coefficients | Amplification | Organic chemistry | Resists | Organotin compounds | Attenuation | Polarity | Cleavage | Cations | Sensitivity enhancement | Absorption cross sections
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6. Full Text Conversion of a Signal into Forces for Axon Outgrowth through Pak1-Mediated Shootin1 Phosphorylation
by Toriyama, Michinori and Kozawa, Satoshi and Sakumura, Yuichi and Inagaki, Naoyuki
Current Biology, ISSN 0960-9822, 03/2013, Volume 23, Issue 6, pp. 529 - 534
Soluble guidance cues can direct cellular protrusion and migration by modulating adhesion and cytoskeletal dynamics. Actin filaments (F-actins) polymerize at... 
CDC42 | ADHESION | CELL-MIGRATION | SUBSTRATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DYNAMICS | NEURONAL POLARITY | ACTIN-FILAMENTS | N-WASP | MYOSIN-II | GROWTH CONE | CELL BIOLOGY | Growth Cones - physiology | Phosphorylation | Tumor Suppressor Proteins - metabolism | Signal Transduction | Netrin-1 | Actins - metabolism | Cells, Cultured | Rats | Nerve Growth Factors - metabolism | p21-Activated Kinases - metabolism | Nerve Tissue Proteins - metabolism | Animals | Mass Spectrometry | Hippocampus - physiology | Hippocampus - growth & development | Muscle proteins | Myosin
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7. Full Text Incorporation of chemical amplification in dual insolubilization resists
by Enomoto, Satoshi and Yoshino, Takumi and Machida, Kohei and Kozawa, Takahiro
Japanese Journal of Applied Physics, ISSN 0021-4922, 2019, Volume 58, Issue 5, p. 56504
Acid diffusion in chemically amplified resists (CARs)-currently the standard resists for semiconductor device manufacturing-is a significant concern in the... 
PHYSICS, APPLIED | ACID | Amplification | Organic chemistry | Sensitivity | Electron beams | Acids | Resists | Crosslinking | Polarity | Catalysis | Automobiles | Dimerization
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8. Full Text Shootin1-cortactin interaction mediates signal-force transduction for axon outgrowth
by Kubo, Yusuke and Kubo, Yusuke and Baba, Kentarou and Baba, Kentarou and Toriyama, Michinori and Toriyama, Michinori and Minegishi, Takunori and Minegishi, Takunori and Sugiura, Tadao and Sugiura, Tadao and Kozawa, Satoshi and Kozawa, Satoshi and Ikeda, Kazushi and Ikeda, Kazushi and Inagaki, Naoyuki and Inagaki, Naoyuki
The Journal of cell biology, ISSN 0021-9525, 08/2015, Volume 210, Issue 4, pp. 663 - 676
Motile cells transduce environmental chemical signals into mechanical forces to achieve properly controlled migration. This signal-force transduction is... 
Growth Cones - physiology | Phosphorylation | Tumor Suppressor Proteins - metabolism | Netrin-1 | Actins - metabolism | Cercopithecus aethiops | Rats | Nerve Growth Factors - metabolism | Cortactin - metabolism | p21-Activated Kinases - metabolism | Nerve Tissue Proteins - metabolism | Animals | Protein Binding | Protein Processing, Post-Translational | COS Cells
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9. Full Text Low-dose chemotherapy with methotrexate and vinblastine for patients with desmoid tumors: relationship to CTNNB1 mutation status
by Nishida, Yoshihiro and Tsukushi, Satoshi and Urakawa, Hiroshi and Hamada, Shunsuke and Kozawa, Eiji and Ikuta, Kunihiro and Ando, Yuichi and Ishiguro, Naoki
International Journal of Clinical Oncology, ISSN 1341-9625, 12/2015, Volume 20, Issue 6, pp. 1211 - 1217
This study was conducted to determine the efficacy and safety of low-dose chemotherapy with methotrexate (MTX) and vinblastine (VBL) for patients with desmoid... 
Vinblastine | Medicine & Public Health | Oncology | Cancer Research | CTNNB1 | Methotrexate | Surgical Oncology | Desmoid tumor | SURGERY | PROGNOSTIC-FACTORS | EFFICACY | SEE POLICY | RADIATION-THERAPY | CHILDREN | PHASE-II TRIAL | ONCOLOGY | ADVANCED AGGRESSIVE FIBROMATOSIS | FRENCH SARCOMA GROUP | IMATINIB | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Thiazines - therapeutic use | Drug Administration Schedule | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Drug Resistance, Neoplasm | Male | Thiazoles - therapeutic use | Vinblastine - administration & dosage | Fibromatosis, Abdominal - drug therapy | beta Catenin - genetics | Young Adult | Retreatment | Cyclooxygenase 2 Inhibitors - therapeutic use | Adult | Female | Fibromatosis, Abdominal - genetics | Methotrexate - administration & dosage | Aged | Mutation | Child | Meloxicam | COX-2 inhibitors | Medical colleges | Care and treatment | Chemotherapy | Analysis | Dosage and administration | Genetic aspects | Health aspects | Tumors | Cancer | Index Medicus
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10. Full Text Multiple variations of the cerebral arteries associated with tetralogy of Fallot: a case report
by Uchino, Akira and Saito, Naoko and Kozawa, Eito and Masutani, Satoshi
Surgical and Radiologic Anatomy, ISSN 0930-1038, 10/2017, Volume 39, Issue 10, pp. 1161 - 1164
Tetralogy of Fallot (TOF) can be associated with vascular malformations or variations, especially of the aortic arch or supracardiac major venous systems. We... 
Tetralogy of Fallot | Persistent hypoglossal artery | Medicine & Public Health | Cerebral arterial variation | Surgery | Orthopedics | Internal carotid artery | Middle cerebral artery | Imaging / Radiology | Anatomy | Anterior cerebral artery | SURGERY | PERSISTENT | PRIMITIVE HYPOGLOSSAL ARTERY | ANATOMY & MORPHOLOGY | PULMONARY-ATRESIA | ARCH | ANGIOGRAPHY | ATRIAL SEPTAL-DEFECT | ANEURYSM | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Cerebral Arteries - abnormalities | Cerebral Arteries - diagnostic imaging | Humans | Abnormalities, Multiple | Magnetic Resonance Angiography | Female | Tomography, X-Ray Computed | Child | Cerebral Infarction - diagnostic imaging | Medical colleges | Cardiology | Arteries | Brain | Angiography | Aortic arch | Anastomosis | Aneurysms | Aorta | Anatomy & physiology | Veins & arteries
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11. Full Text (−)-Epigallocatechin gallate downregulates EGF receptor via phosphorylation at Ser1046/1047 by p38 MAPK in colon cancer cells
by Adachi, Seiji and Shimizu, Masahito and Shirakami, Yohei and Yamauchi, Junichi and Natsume, Hideo and Matsushima-Nishiwaki, Rie and To, Satoshi and Weinstein, I.Bernard and Moriwaki, Hisataka and Kozawa, Osamu
Carcinogenesis, ISSN 0143-3334, 9/2009, Volume 30, Issue 9, pp. 1544 - 1552
We previously reported that (−)-epigallocatechin gallate (EGCG) in green tea alters plasma membrane organization and causes internalization of epidermal growth... 
SIGNAL-TRANSDUCTION | INTERNALIZATION | ACTIVATED PROTEIN-KINASE | ONCOLOGY | TYROSINE KINASE | C-CBL | DESENSITIZATION | EPIDERMAL-GROWTH-FACTOR | STRESS | CYTOTOXICITY | FACTOR-ALPHA | Phosphorylation | Proto-Oncogene Proteins c-cbl - metabolism | p38 Mitogen-Activated Protein Kinases - physiology | Colonic Neoplasms - prevention & control | Down-Regulation | Humans | Imidazoles - pharmacology | Serine - metabolism | Colonic Neoplasms - metabolism | Receptor, Epidermal Growth Factor - metabolism | Colonic Neoplasms - pathology | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Catechin - analogs & derivatives | Pyridines - pharmacology | Catechin - pharmacology | Anticarcinogenic Agents - pharmacology | Index Medicus
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12. Full Text Real-time prediction of cell division timing in developing zebrafish embryo
by Kozawa, Satoshi and Akanuma, Takashi and Sato, Tetsuo and Sato, Yasuomi D and Ikeda, Kazushi and Sato, Thomas N
Scientific Reports, ISSN 2045-2322, 09/2016, Volume 6, Issue 1, p. 32962
Combination of live-imaging and live-manipulation of developing embryos in vivo provides a useful tool to study developmental processes. Identification and... 
SHAPE | MULTIDISCIPLINARY SCIENCES | Cell Line | Microscopy, Confocal | Animals | Cell Division | Bayes Theorem | Embryonic Development | Neural Stem Cells - cytology | Zebrafish - embryology | Decision making | Cell division | Neural stem cells | Zebrafish | Mathematics | Mathematical models | Embryos | Bayesian analysis
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13. Full Text Re-evaluating the functional landscape of the cardiovascular system during development
by Takada, Norio and Omae, Madoka and Sagawa, Fumihiko and Chi, Neil C and Endo, Satsuki and Kozawa, Satoshi and Sato, Thomas N
Biology Open, ISSN 2046-6390, 11/2017, Volume 6, Issue 11, pp. 1756 - 1770
The cardiovascular system facilitates body-wide distribution of oxygen, a vital process for the development and survival of virtually all vertebrates. However,... 
Cardiovascular system | Olfactory marker protein | Hypoxia | Retinol binding protein | Transcriptome | Body-wide landscape | EMBRYONIC-DEVELOPMENT | LIPID-METABOLISM | ZEBRAFISH | DIGESTIVE-SYSTEM | REGENERATION | VITAMIN-A | ENDOTHELIAL-CELLS | GROWTH | BIOLOGY | ANGIOCRINE SIGNALS | DIFFERENTIATION | Heart | Vertebrates | Zebrafish | Oxygen | Organs
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14. Full Text Pulse radiolysis of methacrylic acid ligand for zirconia nanoparticle resist
by Yamada, Teppei and Ishihara, Satoshi and Muroya, Yusa and Santillan, Julius Joseph and Yamashita, Shinichi and Itani, Toshiro and Kozawa, Takahiro
Japanese Journal of Applied Physics, ISSN 0021-4922, 03/2019, Volume 58, Issue 3, p. 36503
The trade-off relationships between resolution, line width roughness (LWR) and sensitivity is the most serious problem in the development of resist materials.... 
PHYSICS, APPLIED | SPECTRA | PHOTORESISTS | KINETICS | WATER | Metal oxides | Nanoparticles | Chemical industry | Radiation effects | Tradeoffs | Resists | Radiolysis | Methacrylic acid | Ligands | Zirconium dioxide
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15. Formation of Au nanoparticle arrays on hydrogel two-dimensional patterns based on poly(vinylpyrrolidone)
by Satoshi Tsukuda and Kazumasa Okamoto and Hiroki Yamamoto and Takahiro Kozawa and Takahisa Omata
Japanese Journal of Applied Physics, ISSN 0021-4922, 06/2017, Volume 56, Issue 6, p. 06GG06
In this study, we demonstrated the formation of Au nanoparticle (NP) arrays on two-dimensional gel patterns based on poly(vinylpyrrolidone) (PVP), which were... 
Nanoparticles | Gold | Ultraviolet radiation | Hydrogels | Electron beam lithography | Irradiation | Crosslinking | Arrays | Surface treatment | Photochemistry
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16. Full Text Eco-friendly electron beam lithography using water-developable resist material derived from biomass
by Takei, Satoshi and Oshima, Akihiro and Wakabayashi, Takanori and Kozawa, Takahiro and Tagawa, Seiichi
Applied Physics Letters, ISSN 0003-6951, 07/2012, Volume 101, Issue 3, p. 33106
We investigated the eco-friendly electron beam (EB) lithography using a high-sensitive negative type of water-developable resist material derived from biomass... 
PHYSICS, APPLIED | FABRICATION | Amplification | Electron beam lithography | Lithography | Materials handling | Resists | Images | Etching | Biomass
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17. Full Text The 14th Asia Pacific Conference on Disaster Medicine in Kobe, Japan: A Brief Overview and a Proposal
by Nakayama, Shinichi and Ukai, Takashi and Kozawa, Shuichi and Kawase, Tetsunori and Ishihara, Satoshi and Kai Kai, Soichiro and Kayano, Ryoma and Kai, Tatsuro
Prehospital and Disaster Medicine, ISSN 1049-023X, 05/2019, Volume 34, Issue s1, pp. s98 - s99
Introduction:The Asia Pacific Conference on Disaster Medicine (APCDM) started in 1988 in Osaka, Japan, and the 14th conference was held from October 16-182,... 
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18. Full Text Triglyceride deposit cardiomyovasculopathy: a rare cardiovascular disorder
by Li, M and Hirano, K and Ikeda, Y and Higashi, M and Hashimoto, C and Zhang, B and Kozawa, J and Sugimura, K and Miyauchi, H and Suzuki, A and Hara, Y and Takagi, A and Kobayashi, K and Futsukaichi, Y and Zaima, N and Yamaguchi, S and Shrestha, R and Nakamura, H and Kawaguchi, K and Sai, E and Hui, SP and Nakano, Y and Sawamura, A and Inaba, T and Sakata, Y and Yasui, Y and Nagasawa, Y and Kinugawa, S and Shimada, K and Yamada, S and Hao, H and Nakatani, D and Ide, T and Amano, T and Naito, H and Nagasaka, H and Japan TGCV Study Grp and Japan TGCV study group and on behalf of the Japan TGCV study group
ORPHANET JOURNAL OF RARE DISEASES, ISSN 1750-1172, 06/2019, Volume 14, Issue 1, pp. 134 - 9
Triglyceride deposit cardiomyovasculopathy (TGCV) is a phenotype primarily reported in patients carrying genetic mutations in PNPLA2 encoding adipose... 
AUTOMATED HEMATOLOGY ANALYZER | MEDICINE, RESEARCH & EXPERIMENTAL | GENETIC DEFICIENCY | CAPRIC ACID CONCENTRATIONS | CARDIOMYOPATHY | PHENOTYPE | MYOPATHY | LIPASE ACTIVITY | Adipose triglyceride lipase | LIPID STORAGE DISEASE | Rare disease | Atherosclerosis | GENETICS & HEREDITY | MUTATIONS | Triglyceride-deposit cardiomyovasculopathy | Triglyceride metabolism | PNPLA2 | Heart | Care and treatment | Usage | Gene mutations | Triglycerides | Transplantation | Research | Cardiovascular diseases | Coronary heart disease | Fatty acids | Phenotypes | Syngeneic grafts | Cardiomyopathy | Heart transplantation | Coronary artery | Cardiomyocytes | Cardiovascular disease | Lipids | Smooth muscle | Lipase | Metabolism | Kinases | Patients | Coronary artery disease | Genotype & phenotype | Coronary vessels | Scientific imaging | Mutation | Mass spectrometry | Heart diseases
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