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1. Full Text Radio Monitoring : Automated Systems and Their Components
by Rembovsky, Anatoly M and Ashikhmin, Alexander V and Kozmin, Vladimir A and Smolskiy, Sergey M
05/2018, Signals and communication technology, ISBN 9783319742762, 486
This book discusses the architecture of modern automated systems for spectrum monitoring including automation components: technical means for spectrum... 
Radio-Equipment and supplies | Radio-Monitoring receivers | Radio-Packet transmission
eBook
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2. Full Text Ligation of Left Atrial Appendage during Off-Pump Coronary Surgery
by Enginoev, Soslan and Koz'min, Dmitry and Magomedov, Gasan and Makeev, Sergey and Chernov, Igor and Ilov, Nikolay and Tarasov, Dmiry and Zhigalov, Konstantin and Weymann, Alexander
The Thoracic and Cardiovascular Surgeon, ISSN 0171-6425, 09/2019
Abstract Objective  The main purpose of this article is to evaluate an impact of epicardial ligation of the left atrial appendage (LAA) in patients with atrial... 
Original Cardiovascular
Journal Article
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3. Full Text Gold and Platinum Catalysis of Enyne Cycloisomerization
by Zhang, Liming and Sun, Jianwei and Kozmin, Sergey A
Advanced Synthesis & Catalysis, ISSN 1615-4150, 11/2006, Volume 348, Issue 16‐17, pp. 2271 - 2296
This account provides a comprehensive overview of the development of gold and platinum catalysis of the enyne cycloisomerization. The use of these soft,... 
gold | platinum | alkenes | CC bond formation | cyclization | alkynes | Gold | Alkenes | C-C bond formation | Cyclization | Platinum | Alkynes | SKELETAL REORGANIZATION | RAUTENSTRAUCH REARRANGEMENT | CHIRALITY TRANSFER | POLYFUNCTIONALIZED 1,6-ENYNES | CHEMISTRY, ORGANIC | PTCL2-CATALYZED CYCLOISOMERIZATIONS | TRANSITION-METALS | PTCL2-MEDIATED CYCLOISOMERIZATION | HIGHLY EFFICIENT | SELECTIVE SYNTHESIS | CHEMISTRY, APPLIED | PROPARGYLIC CARBOXYLATES
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4. Full Text Brønsted Acid-Promoted Cyclizations of Siloxyalkynes with Arenes and Alkenes
by Zhang, Liming and Kozmin, Sergey A
Journal of the American Chemical Society, ISSN 0002-7863, 08/2004, Volume 126, Issue 33, pp. 10204 - 10205
We have described the first Brønsted acid-mediated cyclizations of siloxyalkynes with simple arenes and alkenes to afford substituted tetralone and... 
Chemical bonds | Research | Siloxanes | Olefins
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5. Full Text Gold-Catalyzed Assembly of Heterobicyclic Systems
by Zhang, Liming and Kozmin, Sergey A
Journal of the American Chemical Society, ISSN 0002-7863, 05/2005, Volume 127, Issue 19, pp. 6962 - 6963
We have described an efficient gold-catalyzed double cyclization of 1,5-enynes to afford a range of heterobicyclic compounds, including... 
ALKENES | BENZANNULATION | CYCLIZATIONS | ARENES | CYCLOISOMERIZATION | ALKYNES | CHEMISTRY, MULTIDISCIPLINARY | ENYNES | Chemical reactions | Gold compounds | Research | Chemical properties | Nucleophiles
Journal Article
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6. Full Text Structure of Bistramide A−Actin Complex at a 1.35 Å Resolution
by Rizvi, Syed Alipayam and Tereshko, Valentina and Kossiakoff, Anthony A and Kozmin, Sergey A
Journal of the American Chemical Society, ISSN 0002-7863, 03/2006, Volume 128, Issue 12, pp. 3882 - 3883
Bistramide A is a highly potent antiproliferative marine natural product from Lissoclinum bistratum. We have previously established actin as the primary... 
SKELETAL-MUSCLE FIBERS | BINDING | CHEMISTRY, MULTIDISCIPLINARY | POLYETHER | LISSOCLINUM-BISTRATUM | FILAMENT | Antimitotic agents | Amides | Chemical properties | Antineoplastic agents | Actin
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7. Ligation of Left Atrial Appendage during Off-Pump Coronary Surgery
by Enginoev, Soslan and Koz'min, Dmitry and Magomedov, Gasan and Makeev, Sergey and Chernov, Igor and Ilov, Nikolay and Tarasov, Dmiry and Zhigalov, Konstantin and Weymann, Alexander
The Thoracic and cardiovascular surgeon, 09/2019
The main purpose of this article is to evaluate an impact of epicardial ligation of the left atrial appendage (LAA) in patients with atrial fibrillation (AF)... 
Journal Article
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8. Full Text Rationally Simplified Bistramide Analog Reversibly Targets Actin Polymerization and Inhibits Cancer Progression in Vitro and in Vivo
by Rizvi, Syed Alipayam and Liu, Song and Chen, Zhonglei and Skau, Colleen and Pytynia, Matthew and Kovar, David R and Chmura, Steven J and Kozmin, Sergey A
Journal of the American Chemical Society, ISSN 0002-7863, 06/2010, Volume 132, Issue 21, pp. 7288 - 7290
We describe structure-based design and chemical synthesis of a simplified analog of bistramide A, which potently and reversibly binds monomeric actin with a K... 
FORMINS | COMPLEX | STEREOISOMER | CHEMISTRY, MULTIDISCIPLINARY | LISSOCLINUM-BISTRATUM | Neoplasms - metabolism | Antineoplastic Agents - chemical synthesis | Humans | Actins - metabolism | Antineoplastic Agents - chemistry | Xenograft Model Antitumor Assays | Acetamides - chemistry | Animals | Mice, Nude | Pyrans - chemistry | Drug Design | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Mice | Spiro Compounds - chemistry | Antimitotic agents | Actin | Analysis | Amides | Chemical properties | Structure | Antineoplastic agents | Protein binding
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9. Full Text Gold-Catalyzed Cycloisomerization of Siloxy Enynes to Cyclohexadienes
by Zhang, Liming and Kozmin, Sergey A
Journal of the American Chemical Society, ISSN 0002-7863, 09/2004, Volume 126, Issue 38, pp. 11806 - 11807
We have described the first Au-catalyzed cycloisomerization of 1-siloxy-5-en-1-ynes. The reaction is efficiently catalyzed by AuCl (1 mol %) to afford siloxy... 
SKELETAL REORGANIZATION | CYCLIZATIONS | ALKENE METATHESIS | COMPLEXES | PLATINUM | PTCL2-CATALYZED CYCLOISOMERIZATIONS | PTCL2 | ALKYNES | TRANSITION-METALS | EFFICIENT | CHEMISTRY, MULTIDISCIPLINARY
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10. Full Text Chemical “knockout” challenges the amphotericin B channel model
by Kozmin, Sergey A
Nature Chemical Biology, ISSN 1552-4450, 01/2008, Volume 4, Issue 1, pp. 19 - 20
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11. Full Text Siloxyalkyne–Alkene Metathesis: Rapid Access to Highly Functionalized Enones
by Schramm, Michael P and Reddy, D. Srinivasa and Kozmin, Sergey A
Angewandte Chemie International Edition, ISSN 1433-7851, 11/2001, Volume 40, Issue 22, pp. 4274 - 4277
Mechanistically intriguing participation of siloxyalkynes occurs in the intramolecular Ru‐catalyzed metathesis with terminal alkenes (see scheme;... 
siloxyalkynes | homogeneous catalysis | metathesis | enones | synthetic methods | Siloxyalkynes | Synthetic methods | Enones | Homogeneous catalysis | Metathesis | REARRANGEMENT | ORGANIC-SYNTHESIS | COMPLEX | RING-CLOSING METATHESIS | CONSTRUCTION | ESTERS | DIENYNES | RUTHENIUM | OLEFIN METATHESIS | CHEMISTRY, MULTIDISCIPLINARY | CATALYZED ENYNE METATHESIS
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12. Full Text Synthesis of Streptolydigin, a Potent Bacterial RNA Polymerase Inhibitor
by Pronin, Sergey V and Kozmin, Sergey A
Journal of the American Chemical Society, ISSN 0002-7863, 10/2010, Volume 132, Issue 41, pp. 14394 - 14396
Streptolydigin is a highly potent, broad-spectrum antibiotic produced by Streptomyces lydicus, which inhibits bacterial RNA polymerase. We describe the first... 
ANTIBIOTICS | STRUCTURAL BASIS | MODE | TETRAMIC ACID SUBUNIT | TIRANDAMYCIN | (+/-)-TIRANDAMYCIN-A | TIRANDALYDIGIN | CHEMISTRY, MULTIDISCIPLINARY | Aminoglycosides - chemistry | DNA-Directed RNA Polymerases - antagonists & inhibitors | Streptomyces - chemistry | Aminoglycosides - chemical synthesis | Enzyme inhibitors | Antibiotics | Olefins | Analysis | Chemical properties | Ring formation (Chemistry) | Structure | RNA polymerases
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13. Full Text Chemical "knockout" challenges the amphotericin B channel model
by Kozmin, Sergey A
Nature Chemical Biology, ISSN 1552-4450, 01/2008, Volume 4, Issue 1, pp. 19 - 20
Charge pairing between neighboring amphotericin B molecules inserted into the membrane is believed to significantly stabilize supramolecular channel... 
MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | Antifungal Agents - pharmacology | Ion Channels - metabolism | Models, Chemical | Carboxylic Acids - chemistry | Amphotericin B - pharmacology | Antifungal Agents - chemistry | Lipid Bilayers - chemistry | Lipid Bilayers - metabolism | Amphotericin B - chemistry | Ion Channels - chemistry | Membranes | Biochemistry | Models | Cellular biology | Acids | Molecular biology
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14. Full Text Synthesis of an azide-tagged library of 2,3-dihydro-4-quinones
by Hajoong Lee and Suzuki, Masato and Jiayue Cui and Kozmin, Sergey A
Journal of Organic Chemistry, ISSN 0022-3263, 03/2010, Volume 75, Issue 5, p. 1756
Azides | Usage | Analysis | Quinone | Fluorescence | Chemical properties | Structure | Chromatography
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15. Creation and manipulation of common functional groups en route to a skeletally diverse chemical library
by Jiayue Cui and Jason Hao and Olesya A Ulanovskaya and Joseph Dundas and Jie Liang and Sergey A Kozmin
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 04/2011, Volume 108, Issue 17, p. 6763
We have developed an efficient strategy to a skeletally diverse chemical library, which entailed a sequence of enyne cycloisomerization, [4 + 2] cycloaddition,... 
Molecules | Glycoproteins | Organic chemicals | Chemical synthesis | Physical properties | Adenosine triphosphatase | Cells
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16. Full Text Label-assisted mass spectrometry for the acceleration of reaction discovery and optimization
by Cabrera-Pardo, Jaime R and Chai, David I and Liu, Song and Mrksich, Milan and Kozmin, Sergey A
Nature Chemistry, ISSN 1755-4330, 03/2013, Volume 5, Issue 5, pp. 423 - 427
The identification of new reactions expands our knowledge of chemical reactivity and enables new synthetic applications. Accelerating the pace of this... 
SYSTEM | OLIGOSACCHARIDES | ACID-PROMOTED CYCLIZATIONS | CYCLOADDITIONS | STRATEGY | SILOXY ALKYNES | TRANSFER IONIZATION | SELECTION | CHEMISTRY, MULTIDISCIPLINARY | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods | Drug Discovery
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17. Full Text Spirofungin A: Stereoselective Synthesis and Inhibition of Isoleucyl‐tRNA Synthetase
by Marjanovic, Jasmina and Kozmin, Sergey A
Angewandte Chemie International Edition, ISSN 1433-7851, 11/2007, Volume 46, Issue 46, pp. 8854 - 8857
Lock it in: A temporary silicon‐based configurational lock (see scheme) has enabled an efficient and fully diastereoselective assembly of the spiroketal... 
natural products | spiroketals | stereocontrolled synthesis | metathesis | tRNA synthetase | Spiroketals | Stereocontrolled synthesis | Natural products | Metathesis | REVEROMYCIN-A | ACTIN | CROSS | EUKARYOTIC CELL-GROWTH | CHEMISTRY, MULTIDISCIPLINARY | BISTRAMIDE-A | Antineoplastic Agents - metabolism | Streptomyces - metabolism | Humans | Spiro Compounds - chemical synthesis | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Molecular Structure | Spiro Compounds - pharmacology | Isoleucine-tRNA Ligase - antagonists & inhibitors | Spiro Compounds - metabolism
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18. Full Text Emulating the Logic of Monoterpenoid Alkaloid Biogenesis to Access a Skeletally Diverse Chemical Library
by Liu, Song and Scotti, John S and Kozmin, Sergey A
The Journal of Organic Chemistry, ISSN 0022-3263, 09/2013, Volume 78, Issue 17, pp. 8645 - 8654
We have developed a synthetic strategy that mimics the diversity-generating power of monoterpenoid indole alkaloid biosynthesis. Our general approach goes... 
PHASE | ENZYME | PATHWAY | BIOSYNTHESIS | CHEMISTRY | CHEMISTRY, ORGANIC | DISCOVERY | MOLECULES | Small Molecule Libraries - chemistry | Models, Molecular | Monoterpenes - chemistry | Small Molecule Libraries - chemical synthesis | Alkaloids - chemical synthesis | Molecular Structure | Alkaloids - chemistry | Monoterpenes - chemical synthesis | Measurement | Alkaloids | Chemical reaction, Rate of | Analysis | Crystals | Chemical properties | Structure | Surface energy
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19. Full Text Silver-Promoted Benzannulations of Siloxy Alkynes with Pyridinium and Isoquinolinium Salts
by Cabrera-Pardo, Jaime R and Chai, David I and Kozmin, Sergey A
Advanced synthesis & catalysis, ISSN 1615-4150, 09/2013, Volume 355, Issue 13, pp. 2495 - 2498
We describe the development of efficient benzannulations of siloxy alkynes with pyridinium and isoquinolinium salts. Such reactions are successfully promoted... 
silver | cycloaddition | benzannulation | alkynes
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20. Full Text Identification of Fumarate Hydratase Inhibitors with Nutrient-Dependent Cytotoxicity
by Takeuchi, Toshifumi and Schumacker, Paul T and Kozmin, Sergey A
Journal of the American Chemical Society, ISSN 0002-7863, 01/2015, Volume 137, Issue 2, pp. 564 - 567
Development of cell-permeable small molecules that target enzymes involved in energy metabolism remains important yet challenging. We describe here the... 
TARGET | CELLS | TCA CYCLE | GLUCOSE | MITOCHONDRIA | LIBRARY | MUTATIONS | ENERGY-METABOLISM | CANCER | CHEMISTRY, MULTIDISCIPLINARY | REVEALS | Fumarate Hydratase - metabolism | High-Throughput Screening Assays | Enzyme Inhibitors - toxicity | Humans | Citric Acid Cycle - drug effects | Enzyme Inhibitors - pharmacology | Cell Line, Tumor | Glucose - metabolism | Fumarate Hydratase - antagonists & inhibitors | Drug Evaluation, Preclinical | Energy Metabolism - drug effects | Pharmacology | Structure | Analysis | Cancer cells | Communication
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