Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 09/2004, Volume 5, Issue 9, pp. 687 - 698
Our understanding of the movement of water through cell membranes has been greatly advanced by the discovery of a family of water-specific, membrane-channel...
INDUCED DOWN-REGULATION | COLLECTING DUCT | RAT-KIDNEY | LUNG FLUID TRANSPORT | INTRACELLULAR VESICLES | CO2 PERMEABILITY | NEPHROGENIC DIABETES-INSIPIDUS | WATER CHANNEL EXPRESSION | MOLECULAR-BASIS | BRAIN EDEMA | CELL BIOLOGY | Humans | Aquaporins - chemistry | Homeostasis | Phylogeny | Aquaporins - genetics | Tissue Distribution | Aquaporins - classification | Kidney - metabolism | Protein Isoforms - metabolism | Protein Isoforms - classification | Protein Isoforms - chemistry | Cell Membrane - metabolism | Astrocytes - cytology | Eye - metabolism | Eye - anatomy & histology | Water - metabolism | Aquaporins - metabolism | Kidney - anatomy & histology | Permeability | Respiratory System - anatomy & histology | Animals | Respiratory System - metabolism | Protein Conformation | Astrocytes - metabolism | Protein Isoforms - genetics
INDUCED DOWN-REGULATION | COLLECTING DUCT | RAT-KIDNEY | LUNG FLUID TRANSPORT | INTRACELLULAR VESICLES | CO2 PERMEABILITY | NEPHROGENIC DIABETES-INSIPIDUS | WATER CHANNEL EXPRESSION | MOLECULAR-BASIS | BRAIN EDEMA | CELL BIOLOGY | Humans | Aquaporins - chemistry | Homeostasis | Phylogeny | Aquaporins - genetics | Tissue Distribution | Aquaporins - classification | Kidney - metabolism | Protein Isoforms - metabolism | Protein Isoforms - classification | Protein Isoforms - chemistry | Cell Membrane - metabolism | Astrocytes - cytology | Eye - metabolism | Eye - anatomy & histology | Water - metabolism | Aquaporins - metabolism | Kidney - anatomy & histology | Permeability | Respiratory System - anatomy & histology | Animals | Respiratory System - metabolism | Protein Conformation | Astrocytes - metabolism | Protein Isoforms - genetics
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2014, Volume 89, Issue 4, pp. 880 - 887
Purpose Although palliative chemotherapy is the standard of care for patients with diagnoses of stage IV non-small cell lung cancer (NSCLC), patients with a...
Radiology | Hematology, Oncology and Palliative Medicine | ADRENAL METASTASES | SURVIVAL | RADICAL TREATMENT | PHASE-II-TRIAL | MANAGEMENT | PROGNOSTIC-FACTORS | BRAIN METASTASIS | ONCOLOGY | RESECTION | SURGICAL-TREATMENT | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | RADIATION-THERAPY | Bone Neoplasms - mortality | Bone Neoplasms - therapy | Lung Neoplasms - mortality | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Bone Neoplasms - secondary | Lung Neoplasms - pathology | Male | Carcinoma, Squamous Cell - diagnostic imaging | Adrenal Gland Neoplasms - mortality | Brain Neoplasms - secondary | Carcinoma, Non-Small-Cell Lung - secondary | Carcinoma, Squamous Cell - mortality | Adrenal Gland Neoplasms - secondary | Female | Retrospective Studies | Brain Neoplasms - mortality | Databases, Factual | Carcinoma, Non-Small-Cell Lung - pathology | Severity of Illness Index | Carcinoma, Squamous Cell - therapy | Lung Neoplasms - therapy | Carcinoma, Non-Small-Cell Lung - mortality | Radiography | Propensity Score | Carcinoma, Non-Small-Cell Lung - therapy | Analysis of Variance | Brain Neoplasms - therapy | Carcinoma, Squamous Cell - secondary | Lung Neoplasms - diagnostic imaging | Aged | Carcinoma, Non-Small-Cell Lung - diagnostic imaging | Neoplasm Staging | Adrenal Gland Neoplasms - therapy | Lung cancer, Small cell | Chemotherapy | Lung cancer, Non-small cell | Cancer | DIAGNOSIS | PATIENTS | NEOPLASMS | LUNGS | METASTASES | RADIOLOGY AND NUCLEAR MEDICINE | HISTOLOGY | CHEMOTHERAPY | HAZARDS
Radiology | Hematology, Oncology and Palliative Medicine | ADRENAL METASTASES | SURVIVAL | RADICAL TREATMENT | PHASE-II-TRIAL | MANAGEMENT | PROGNOSTIC-FACTORS | BRAIN METASTASIS | ONCOLOGY | RESECTION | SURGICAL-TREATMENT | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | RADIATION-THERAPY | Bone Neoplasms - mortality | Bone Neoplasms - therapy | Lung Neoplasms - mortality | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Bone Neoplasms - secondary | Lung Neoplasms - pathology | Male | Carcinoma, Squamous Cell - diagnostic imaging | Adrenal Gland Neoplasms - mortality | Brain Neoplasms - secondary | Carcinoma, Non-Small-Cell Lung - secondary | Carcinoma, Squamous Cell - mortality | Adrenal Gland Neoplasms - secondary | Female | Retrospective Studies | Brain Neoplasms - mortality | Databases, Factual | Carcinoma, Non-Small-Cell Lung - pathology | Severity of Illness Index | Carcinoma, Squamous Cell - therapy | Lung Neoplasms - therapy | Carcinoma, Non-Small-Cell Lung - mortality | Radiography | Propensity Score | Carcinoma, Non-Small-Cell Lung - therapy | Analysis of Variance | Brain Neoplasms - therapy | Carcinoma, Squamous Cell - secondary | Lung Neoplasms - diagnostic imaging | Aged | Carcinoma, Non-Small-Cell Lung - diagnostic imaging | Neoplasm Staging | Adrenal Gland Neoplasms - therapy | Lung cancer, Small cell | Chemotherapy | Lung cancer, Non-small cell | Cancer | DIAGNOSIS | PATIENTS | NEOPLASMS | LUNGS | METASTASES | RADIOLOGY AND NUCLEAR MEDICINE | HISTOLOGY | CHEMOTHERAPY | HAZARDS
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, p. e94859
Purpose: To examine the frequency and potential of dose-volume predictors for chest wall (CW) toxicity (pain and/or rib fracture) for patients receiving lung...
IRRADIATION | MULTIDISCIPLINARY SCIENCES | PHASE-II | TOXICITY | RADIOTHERAPY | OUTCOMES | CANCER | Care and treatment | Fractures | Radiotherapy | Health aspects | Analysis | Radiation | Chest | Thoracic surgery | Dosimeters | Toxicity | Lung cancer | Oncology | Risk | Multivariate analysis | Cancer therapies | Medical schools | Optimization | Incidence | Biological effects | Pain | Dosimetry | Fractionation | Rib | Radiation therapy | Regression analysis | Patients | Hospitals | Lungs | Womens health | Tumors
IRRADIATION | MULTIDISCIPLINARY SCIENCES | PHASE-II | TOXICITY | RADIOTHERAPY | OUTCOMES | CANCER | Care and treatment | Fractures | Radiotherapy | Health aspects | Analysis | Radiation | Chest | Thoracic surgery | Dosimeters | Toxicity | Lung cancer | Oncology | Risk | Multivariate analysis | Cancer therapies | Medical schools | Optimization | Incidence | Biological effects | Pain | Dosimetry | Fractionation | Rib | Radiation therapy | Regression analysis | Patients | Hospitals | Lungs | Womens health | Tumors
Journal Article
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Full Text
Updated patterns of failure after multimodality therapy for malignant pleural mesothelioma
Journal of Thoracic and Cardiovascular Surgery, The, ISSN 0022-5223, 2015, Volume 149, Issue 5, pp. 1374 - 1381
Abstract Objective We have previously described patterns of failure after extrapleural pneumonectomy and multimodality therapy for malignant pleural...
Cardiothoracic Surgery | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | INDUCTION CHEMOTHERAPY | INTENSITY-MODULATED RADIOTHERAPY | SURGICAL-TREATMENT | PHASE-II TRIAL | DOSE HEMITHORACIC RADIATION | RESPIRATORY SYSTEM | EXTRAPLEURAL PNEUMONECTOMY | TRIMODALITY THERAPY | HYPERTHERMIC CISPLATIN | CLINICAL-OUTCOMES | Predictive Value of Tests | Pneumonectomy - mortality | Lung Neoplasms - mortality | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Mesothelioma - mortality | Tomography, X-Ray Computed | Positron-Emission Tomography | Multimodal Imaging | Mesothelioma - secondary | Lung Neoplasms - secondary | Time Factors | Treatment Failure | Boston - epidemiology | Adult | Female | Neoadjuvant Therapy | Registries | Retrospective Studies | Chemotherapy, Adjuvant | Radiotherapy, Adjuvant | Pleural Neoplasms - pathology | Radiotherapy Dosage | Pneumonectomy - adverse effects | Mesothelioma - therapy | Risk Factors | Kaplan-Meier Estimate | Neoplasm Recurrence, Local | Proportional Hazards Models | Lung Neoplasms - therapy | Pleural Neoplasms - mortality | Pleural Neoplasms - therapy | Disease Progression | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Mesothelioma | Care and treatment
Cardiothoracic Surgery | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | INDUCTION CHEMOTHERAPY | INTENSITY-MODULATED RADIOTHERAPY | SURGICAL-TREATMENT | PHASE-II TRIAL | DOSE HEMITHORACIC RADIATION | RESPIRATORY SYSTEM | EXTRAPLEURAL PNEUMONECTOMY | TRIMODALITY THERAPY | HYPERTHERMIC CISPLATIN | CLINICAL-OUTCOMES | Predictive Value of Tests | Pneumonectomy - mortality | Lung Neoplasms - mortality | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Mesothelioma - mortality | Tomography, X-Ray Computed | Positron-Emission Tomography | Multimodal Imaging | Mesothelioma - secondary | Lung Neoplasms - secondary | Time Factors | Treatment Failure | Boston - epidemiology | Adult | Female | Neoadjuvant Therapy | Registries | Retrospective Studies | Chemotherapy, Adjuvant | Radiotherapy, Adjuvant | Pleural Neoplasms - pathology | Radiotherapy Dosage | Pneumonectomy - adverse effects | Mesothelioma - therapy | Risk Factors | Kaplan-Meier Estimate | Neoplasm Recurrence, Local | Proportional Hazards Models | Lung Neoplasms - therapy | Pleural Neoplasms - mortality | Pleural Neoplasms - therapy | Disease Progression | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Mesothelioma | Care and treatment
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2015, Volume 112, Issue 30, pp. E4055 - E4064
The available evidence suggests that the lethality of glioblastoma is driven by small subpopulations of cells that self-renew and exhibit tumorigenicity. It...
Epigenomics | Glioblastoma | Neoplastic stem cells | INITIATING CELLS | CANCER-CELLS | GLIOMA | MULTIDISCIPLINARY SCIENCES | MOLECULAR-ORIGINS | TRANSCRIPTION | epigenomics | EMBRYONIC STEM | EGFR | STOCHASTIC GENE-EXPRESSION | glioblastoma | MODELS | neoplastic stem cells | HISTONE MODIFICATIONS | Neoplasms - metabolism | Neoplasm Transplantation | Epigenesis, Genetic | Humans | Mice, Inbred C57BL | Gene Expression Regulation, Neoplastic | Gene Silencing | Male | Gene Expression Profiling | Proto-Oncogene Proteins c-myc - metabolism | Brain Neoplasms - metabolism | Histone Demethylases - metabolism | Animals | Stochastic Processes | Cell Transformation, Neoplastic | Cell Line, Tumor | Glioblastoma - metabolism | Mice | Epigenetic inheritance | Genetic aspects | Observations | Genetic regulation | Gene expression | Glioblastoma multiforme | Biological Sciences | PNAS Plus
Epigenomics | Glioblastoma | Neoplastic stem cells | INITIATING CELLS | CANCER-CELLS | GLIOMA | MULTIDISCIPLINARY SCIENCES | MOLECULAR-ORIGINS | TRANSCRIPTION | epigenomics | EMBRYONIC STEM | EGFR | STOCHASTIC GENE-EXPRESSION | glioblastoma | MODELS | neoplastic stem cells | HISTONE MODIFICATIONS | Neoplasms - metabolism | Neoplasm Transplantation | Epigenesis, Genetic | Humans | Mice, Inbred C57BL | Gene Expression Regulation, Neoplastic | Gene Silencing | Male | Gene Expression Profiling | Proto-Oncogene Proteins c-myc - metabolism | Brain Neoplasms - metabolism | Histone Demethylases - metabolism | Animals | Stochastic Processes | Cell Transformation, Neoplastic | Cell Line, Tumor | Glioblastoma - metabolism | Mice | Epigenetic inheritance | Genetic aspects | Observations | Genetic regulation | Gene expression | Glioblastoma multiforme | Biological Sciences | PNAS Plus
Journal Article
Mathematische Annalen, ISSN 0025-5831, 12/2019, Volume 375, Issue 3, pp. 949 - 972
Consider the (Navier–) Stokes system on an exterior domain with moving boundary and Dirichlet boundary conditions. In 2003 Saal proved that the Stokes operator...
35J65 | Mathematics, general | Mathematics | 76D05 | 35B40 | 35Q30
35J65 | Mathematics, general | Mathematics | 76D05 | 35B40 | 35Q30
Journal Article
Nature Communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, p. 5870
Close resemblance of murine and human trials is essential to achieve the best predictive value of animal-based translational cancer research. Kras-driven...
TRIAL | RESISTANCE | BODY RADIATION-THERAPY | EXPRESSION | MULTIDISCIPLINARY SCIENCES | BIOLOGY | Carcinoma, Non-Small-Cell Lung - radiotherapy | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Lung Neoplasms - metabolism | Radiation Tolerance | Lung Neoplasms - radiotherapy | Lung Neoplasms - pathology | Male | Tumor Suppressor Protein p53 - genetics | Adenoviridae - genetics | Female | Integrases - metabolism | Lentivirus - genetics | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | Proto-Oncogene Proteins p21(ras) - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Gene Expression | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Protein-Serine-Threonine Kinases - genetics | Tumor Suppressor Protein p53 - metabolism | Treatment Outcome | Radiation Dosage | Animals | Radiotherapy, Image-Guided - methods | Mice | Genetic Vectors | Integrases - genetics
TRIAL | RESISTANCE | BODY RADIATION-THERAPY | EXPRESSION | MULTIDISCIPLINARY SCIENCES | BIOLOGY | Carcinoma, Non-Small-Cell Lung - radiotherapy | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Lung Neoplasms - metabolism | Radiation Tolerance | Lung Neoplasms - radiotherapy | Lung Neoplasms - pathology | Male | Tumor Suppressor Protein p53 - genetics | Adenoviridae - genetics | Female | Integrases - metabolism | Lentivirus - genetics | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | Proto-Oncogene Proteins p21(ras) - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Gene Expression | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Protein-Serine-Threonine Kinases - genetics | Tumor Suppressor Protein p53 - metabolism | Treatment Outcome | Radiation Dosage | Animals | Radiotherapy, Image-Guided - methods | Mice | Genetic Vectors | Integrases - genetics
Journal Article
Cell Reports, ISSN 2211-1247, 06/2016, Volume 15, Issue 11, pp. 2488 - 2499
BRCA1/2 proteins function in homologous recombination (HR)-mediated DNA repair and cooperate with Fanconi anemia (FA) proteins to maintain genomic integrity...
GENOMIC INSTABILITY | MONOUBIQUITINATED FANCD2 | REPLICATION FORKS | FANCONI-ANEMIA PATHWAY | CROSS-LINK REPAIR | S PHASE | CTIP | DOUBLE-STRAND BREAKS | HOMOLOGOUS-RECOMBINATION | BRCA1 | CELL BIOLOGY | Genomic Instability | Cell Survival | DNA End-Joining Repair - genetics | Humans | Nuclear Proteins - metabolism | Up-Regulation - genetics | Mutation - genetics | Poly(ADP-ribose) Polymerases - metabolism | Ubiquitination | Animals | BRCA2 Protein - metabolism | Carrier Proteins - metabolism | Fanconi Anemia Complementation Group D2 Protein - metabolism | Neoplasms - genetics | Mice, Nude | BRCA1 Protein - metabolism | Cell Line, Tumor | DNA Replication - genetics | BRCA2 Protein - deficiency | DNA-Directed DNA Polymerase - metabolism | BRCA1 Protein - deficiency | Neoplasms - pathology
GENOMIC INSTABILITY | MONOUBIQUITINATED FANCD2 | REPLICATION FORKS | FANCONI-ANEMIA PATHWAY | CROSS-LINK REPAIR | S PHASE | CTIP | DOUBLE-STRAND BREAKS | HOMOLOGOUS-RECOMBINATION | BRCA1 | CELL BIOLOGY | Genomic Instability | Cell Survival | DNA End-Joining Repair - genetics | Humans | Nuclear Proteins - metabolism | Up-Regulation - genetics | Mutation - genetics | Poly(ADP-ribose) Polymerases - metabolism | Ubiquitination | Animals | BRCA2 Protein - metabolism | Carrier Proteins - metabolism | Fanconi Anemia Complementation Group D2 Protein - metabolism | Neoplasms - genetics | Mice, Nude | BRCA1 Protein - metabolism | Cell Line, Tumor | DNA Replication - genetics | BRCA2 Protein - deficiency | DNA-Directed DNA Polymerase - metabolism | BRCA1 Protein - deficiency | Neoplasms - pathology
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 05/2012, Volume 104, Issue 9, pp. 670 - 681
Background New tools are needed to predict outcomes of ovarian cancer patients treated with platinum-based chemotherapy. We hypothesized that a molecular score...
SURVIVAL | INHIBITION | RECQ HELICASES | CLEAR-CELL | MICROARRAY | ONCOLOGY | ROLES | GENE-EXPRESSION PROFILES | SENSITIVITY PROTEIN MUS308 | HOMOLOGOUS RECOMBINATION | GENOME STABILITY | Predictive Value of Tests | Prognosis | Neoplasms, Glandular and Epithelial - chemistry | Area Under Curve | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Ovarian Neoplasms - pathology | DNA Repair - genetics | Ovarian Neoplasms - genetics | Neoplasms, Glandular and Epithelial - genetics | Adult | Female | Ovarian Neoplasms - drug therapy | DNA Repair - drug effects | Ovarian Neoplasms - chemistry | Biomarkers, Tumor - analysis | Kaplan-Meier Estimate | Proportional Hazards Models | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Carcinoma, Ovarian Epithelial | Aged | Platinum Compounds - administration & dosage | Neoplasm Staging | Care and treatment | Usage | Platinum compounds | Genetic aspects | Research | Gene expression | DNA repair | Health aspects | Ovarian cancer | Statistical analysis | DNA damage | Data processing | Genomes | Survival | Chemotherapy | DNA microarrays | Databases | Platinum | Models | Age | Atlases | Tumors
SURVIVAL | INHIBITION | RECQ HELICASES | CLEAR-CELL | MICROARRAY | ONCOLOGY | ROLES | GENE-EXPRESSION PROFILES | SENSITIVITY PROTEIN MUS308 | HOMOLOGOUS RECOMBINATION | GENOME STABILITY | Predictive Value of Tests | Prognosis | Neoplasms, Glandular and Epithelial - chemistry | Area Under Curve | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Ovarian Neoplasms - pathology | DNA Repair - genetics | Ovarian Neoplasms - genetics | Neoplasms, Glandular and Epithelial - genetics | Adult | Female | Ovarian Neoplasms - drug therapy | DNA Repair - drug effects | Ovarian Neoplasms - chemistry | Biomarkers, Tumor - analysis | Kaplan-Meier Estimate | Proportional Hazards Models | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Carcinoma, Ovarian Epithelial | Aged | Platinum Compounds - administration & dosage | Neoplasm Staging | Care and treatment | Usage | Platinum compounds | Genetic aspects | Research | Gene expression | DNA repair | Health aspects | Ovarian cancer | Statistical analysis | DNA damage | Data processing | Genomes | Survival | Chemotherapy | DNA microarrays | Databases | Platinum | Models | Age | Atlases | Tumors
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 5, p. e10767
Despite the critical role of Epidermal Growth Factor Receptor (EGFR) in glioblastoma pathogenesis [1,2], EGFR targeted therapies have achieved limited clinical...
GROWTH-FACTOR RECEPTOR | CELLS | REPAIR | ACTIVATION | REACTIVE OXYGEN | INSTABILITY | DNA-DAMAGE RESPONSE | MULTIDISCIPLINARY SCIENCES | INTEGRATED GENOMIC ANALYSIS | HUMAN CANCERS | MODULATION | Genomic Instability | Glioblastoma - enzymology | Reactive Oxygen Species - metabolism | Oxidative Stress | Humans | Radiation Tolerance | Gene Expression Regulation, Neoplastic | Treatment Outcome | DNA Repair - genetics | Poly(ADP-ribose) Polymerase Inhibitors | Glioblastoma - therapy | Receptor, Epidermal Growth Factor - metabolism | Glioblastoma - genetics | Survival Analysis | Cell Line, Tumor | DNA Damage | Enzyme Activation | Oxidative stress | Ionizing radiation | Epidermal growth factor | DNA damage | Genes | Gene expression | Health aspects | Glioblastoma multiforme | Sugars | Monosaccharides | Pathogenesis | Glioblastoma | Oncology | Genomes | Kinases | ADP | Cancer therapies | DNA repair | Base excision repair | Genomic instability | Ribose | Tumorigenesis | Inhibition | Repair | Deoxyribonucleic acid--DNA | Medical research | Stability | Epidermal growth factor receptors | Anemia | RNA-mediated interference | Addictions | Polymerase | Poly(ADP-ribose) Polymerase 1 | Overexpression | Addiction | Glioblastoma cells | Mutation | Tumors | Deoxyribonucleic acid | DNA
GROWTH-FACTOR RECEPTOR | CELLS | REPAIR | ACTIVATION | REACTIVE OXYGEN | INSTABILITY | DNA-DAMAGE RESPONSE | MULTIDISCIPLINARY SCIENCES | INTEGRATED GENOMIC ANALYSIS | HUMAN CANCERS | MODULATION | Genomic Instability | Glioblastoma - enzymology | Reactive Oxygen Species - metabolism | Oxidative Stress | Humans | Radiation Tolerance | Gene Expression Regulation, Neoplastic | Treatment Outcome | DNA Repair - genetics | Poly(ADP-ribose) Polymerase Inhibitors | Glioblastoma - therapy | Receptor, Epidermal Growth Factor - metabolism | Glioblastoma - genetics | Survival Analysis | Cell Line, Tumor | DNA Damage | Enzyme Activation | Oxidative stress | Ionizing radiation | Epidermal growth factor | DNA damage | Genes | Gene expression | Health aspects | Glioblastoma multiforme | Sugars | Monosaccharides | Pathogenesis | Glioblastoma | Oncology | Genomes | Kinases | ADP | Cancer therapies | DNA repair | Base excision repair | Genomic instability | Ribose | Tumorigenesis | Inhibition | Repair | Deoxyribonucleic acid--DNA | Medical research | Stability | Epidermal growth factor receptors | Anemia | RNA-mediated interference | Addictions | Polymerase | Poly(ADP-ribose) Polymerase 1 | Overexpression | Addiction | Glioblastoma cells | Mutation | Tumors | Deoxyribonucleic acid | DNA
Journal Article
Cell Stem Cell, ISSN 1934-5909, 05/2016, Volume 18, Issue 5, pp. 668 - 681
Fanconi anemia (FA) is an inherited DNA repair disorder characterized by progressive bone marrow failure (BMF) from hematopoietic stem and progenitor cell...
DNA End-Joining Repair - drug effects | Hematopoietic Stem Cells - drug effects | Cell Survival - drug effects | Mutagens - toxicity | Acetaldehyde - toxicity | Humans | Mice, Inbred C57BL | Hematopoietic Stem Cells - pathology | Down-Regulation - drug effects | Up-Regulation - drug effects | Animals | Signal Transduction - drug effects | Bone Marrow - pathology | Homologous Recombination - genetics | Transforming Growth Factor beta - antagonists & inhibitors | Fanconi Anemia - pathology | Mice | Stress, Physiological - drug effects | Transforming Growth Factor beta - metabolism
DNA End-Joining Repair - drug effects | Hematopoietic Stem Cells - drug effects | Cell Survival - drug effects | Mutagens - toxicity | Acetaldehyde - toxicity | Humans | Mice, Inbred C57BL | Hematopoietic Stem Cells - pathology | Down-Regulation - drug effects | Up-Regulation - drug effects | Animals | Signal Transduction - drug effects | Bone Marrow - pathology | Homologous Recombination - genetics | Transforming Growth Factor beta - antagonists & inhibitors | Fanconi Anemia - pathology | Mice | Stress, Physiological - drug effects | Transforming Growth Factor beta - metabolism
Journal Article
Lung Cancer, ISSN 0169-5002, 2016, Volume 102, pp. 1 - 8
Highlights • Early response assessment of chemoradiation can guide clinical-decision making. • Volume change after chemoradiation is associated with...
Hematology, Oncology and Palliative Medicine | Pulmonary/Respiratory | Rec
Hematology, Oncology and Palliative Medicine | Pulmonary/Respiratory | Rec