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Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. SCI-51 - SCI-51
Abstract Lenalidomide is a derivative of thalidomide, a drug developed in the 1950s as a sedative and treatment for morning sickness that became infamous for... 
Journal Article
Nature, ISSN 0028-0836, 07/2015, Volume 523, Issue 7559, pp. 183 - 188
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 11/2018, Volume 379, Issue 19, pp. 1873 - 1874
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 11/2018, Volume 379, Issue 19, p. 1873
The article discusses the findings of a study by Minzel and colleagues, which revealed the effectiveness of inhibition of cassein kinase 1 alpha in patients... 
Cancer patients | Cellular signal transduction | Research | Health aspects
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 05/2019, Volume 10, Issue 1, pp. 2031 - 11
Mutations in the nucleophosmin 1 (NPM1) gene are considered founder mutations in the pathogenesis of acute myeloid leukemia (AML). To characterize the genetic... 
AML | DIAGNOSIS | STEM-CELLS | HEMATOPOIESIS | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | NORMAL CYTOGENETICS | PROGNOSTIC-SIGNIFICANCE | MINIMAL RESIDUAL DISEASE | YOUNGER ADULT PATIENTS | SOMATIC MUTATIONS | Myeloid leukemia | Pathogenesis | Leukemia | Mutation | Diagnosis | Ribonucleic acid--RNA | Acute myeloid leukemia | Gene sequencing
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 11/2018, Volume 77, Issue 11, pp. 1610 - 1618
BackgroundGlucocorticoid (GC) therapy is frequently used to treat rheumatoid arthritis due to potent anti-inflammatory actions of GCs. Direct actions of GCs on... 
fibroblasts | arthritis | corticosteroids | inflammation | RHEUMATOID-ARTHRITIS | INTERLEUKIN-1 | INHIBITION | THERAPY | ROLES | MACROPHAGES | DISEASE | RESISTANCE | DIMERIZATION | RHEUMATOLOGY | EXPRESSION | Receptors, Glucocorticoid - deficiency | Arthritis, Experimental - drug therapy | Glucocorticoids - therapeutic use | Receptors, Glucocorticoid - metabolism | Arthritis, Experimental - metabolism | Synoviocytes - drug effects | Arthritis, Experimental - pathology | Arthritis, Rheumatoid - metabolism | Synoviocytes - metabolism | Dexamethasone - pharmacology | Arthritis, Rheumatoid - drug therapy | Stromal Cells - drug effects | Anti-Inflammatory Agents - therapeutic use | Dimerization | Anti-Inflammatory Agents - pharmacology | Mice, Inbred C57BL | Stromal Cells - metabolism | Metabolism, Inborn Errors - metabolism | Transplantation Chimera | Arthritis, Rheumatoid - pathology | Gene Expression Regulation - drug effects | Dexamethasone - therapeutic use | Animals | Glucocorticoids - pharmacology | Mice, Inbred BALB C | Metabolism, Inborn Errors - pathology | Receptors, Glucocorticoid - physiology | Cytokines - biosynthesis | Flow cytometry | Dexamethasone | Cytokines | Glucocorticoids | Gene regulation | Liver | Inflammation | CD36 antigen | Kinases | Gene expression | Synoviocytes | Variance analysis | Axl protein | Hemopoiesis | Ankle | CD163 antigen | Gene flow | Rheumatoid arthritis | Stromal cells | Rodents | Collagen | Fibroblasts | Bone marrow | Macrophage inflammatory protein | 2311 | Basic and Translational Research | 1506
Journal Article
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 4045 - 4045
Abstract Introduction Recently, progress has been made in the treatment of patients with higher risk myelodysplastic syndromes (HR MDS) and acute myeloid... 
Journal Article
OncoImmunology, ISSN 2162-4011, 07/2014, Volume 3, Issue 7, p. e941742
Lenalidomide and its analogs, thalidomide and pomalidomide, specifically inhibit growth of mature B-cell lymphomas, including multiple myeloma, and induce... 
lenalidomide | thalidomide | pomalidomide | ubiquitin | Ubiquitin | Pomalidomide | Lenalidomide | Thalidomide | ONCOLOGY | UBIQUITIN LIGASE | IKAROS | LYMPHOMA | LEUKEMIA | IMMUNOLOGY | AIOLOS | T-CELLS
Journal Article
Haematologica, ISSN 0390-6078, 11/2017, Volume 102, Issue 12, pp. 2039 - 2047
In acute myeloid leukemia, there is growing evidence for splicing pattern deregulation, including differential expression of linear splice isoforms of the... 
ABUNDANT | BIOGENESIS | LANDSCAPE | TOLL-LIKE RECEPTORS | CLASSIFICATION | MUTATIONS | HEMATOLOGY | MICRORNA EXPRESSION | CANCER | Gene Expression | RNA Splicing | RNA - analysis | Humans | Nuclear Proteins - genetics | Case-Control Studies | Leukemia, Myeloid, Acute - genetics
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 07/2017, Volume 214, Issue 7, pp. 2121 - 2138
Journal Article